Introduction to Skin Syndrome

What is/are Skin Syndrome?

Skin Syndrome - Here, we announce the complete genome sequence of an exfoliative toxin-producing strain of Staphylococcus aureus sequence type 582 (ST582), isolated from a case of staphylococcal scalded-skin syndrome. ^[1] The main clinical manifestations of SS: the duration of the disease (months), skin count (points), the activity of the disease (points), the duration of skin syndrome (months) and the duration of vascular syndrome (months) showed statistically significant linear and non-linear correlation with seven MC parameters: the value of the arteriolo- to-venule ratio (AVR), five parameters characterizing the density of capillaries on the bulbar conjunctiva and the average diameter of capillaries. ^[2] As a result, an excessive activation of interferon synthesis occurs and a systemic inflammatory reaction develops with symptoms such as febrile fever, skin syndrome, represented by nodules and maculopapular rash, hepatosplenomegaly, lipodystrophy, amyotrophy, delayed physical development, as well as high laboratory activity. ^[3] The skin syndrome completely resolved. ^[4] The therapy effectiveness was assessed based on regression of skin syndrome clinical and gastrointestinal manifestations, intoxication syndrome and laboratory parameters (IgE, hemogram eosinophilia duration). ^[5]

superficial blistering skin

Objective: Staphylococcal scalded skin syndrome (SSSS) is a relatively rare superficial blistering skin disease caused by exfoliating toxins produced by Staphylococcus aureus. ^[1] Staphylococcal scalded skin syndrome (SSSS) describes a spectrum of superficial blistering skin disorders caused by the exfoliative toxins of Staphylococcus aureus  that originates from a focus of infection that may be a purulent conjunctivitis, otitis media, or occult nasopharyngeal infection. ^[2] Staphylococcal scalded skin syndrome (SSSS) describes a spectrum of superficial blistering skin disorders caused by the exfoliative toxins of Staphylococcus aureus that originates from a focus of infection that may be a purulent conjunctivitis, otitis media, or occult nasopharyngeal infection. ^[3]

Scalded Skin Syndrome

Optimal management of staphylococcal scalded skin syndrome (SSSS) has not been established. ^[1] Staphylococcal scalded skin syndrome presents with erythema and swelling that similarly favor the head and intertriginous sites with subsequent bullae formation. ^[2] Staphylococcal Scalded Skin Syndrome (SSSS) is as well called as Ritter von Ritterschein disease, Lyell disease, Ritter disease and staphylococcal necrolysis of the epidermis. ^[3] Staphylococcal-scalded skin syndrome (SSSS) is also known as Ritter's disease. ^[4] 02) and in staphylococcal scalded skin syndrome prevalence (OR 3. ^[5] Objective: Staphylococcal scalded skin syndrome (SSSS) is a relatively rare superficial blistering skin disease caused by exfoliating toxins produced by Staphylococcus aureus. ^[6] Background Staphylococcal Scalded Skin Syndrome (SSSS) is caused by a special type of Staphylococcus aureus (S. ^[7] Background: Staphylococcal Scalded Skin Syndrome (SSSS) is caused by a special type of Staphylococcus aureus (S. ^[8] Eight patients had clinical evidence of infection: one each with central port infection by methicillin-sensitive Staphylococcus aureus, recurrent streptococcal pharyngitis and recent otitis media, streptococcal pharyngitis demonstrated 8 months after biopsy, suspected streptococcal scalded skin syndrome, and viral gastroenteritis, and three with serologic evidence of Streptococcal infection but no identified site of infection. ^[9] Blisters and erosions in AEI are widespread; hence, initially, it is sometimes mistaken with epidermolysis bullosa, acrodermatitis enteropathica, and staphylococcal scalded skin syndrome. ^[10] Background Staphylococcal scalded skin syndrome (SSSS) is a skin disease characterized by blistering and desquamation caused by exfoliative toxins (ETs) of Staphylococcus aureus (S. ^[11] Staphylococcal scalded skin syndrome (SSSS) is characterized by superficial blistering of the skin caused by exfoliative toxins of Staphylococcus aureus. ^[12] Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. ^[13] It manifests itself as a mild form of staphylococcal scalded skin syndrome, being characterized by a scarlet fever exanthema (without blistering), fever and affection of the general condition, with progression to desquamation in large flaps. ^[14] BACKGROUND Controversy exists regarding the optimal antibiotic regimen for use in hospitalized children with staphylococcal scalded skin syndrome (SSSS). ^[15] The term staphylococcal scalded skin syndrome (SSSS) was separated from the toxic or allergic epidermal necrolysis by Lyell into the opposite anatomical aspect of these two entities: in scalded skin syndrome, Skin detachment is done by cleavage of the superficial part of the epidermis at the granular layer, while in toxic Lyell syndrome, the cleavage sits deeper at the level of the mucous body. ^[16] It progressed to a superficial widespread skin peeling and he was treated for a presumed diagnosis of staphylococcal-scalded skin syndrome with oral flucloxacillin, topical emollients and Dermol 500 to wash with. ^[17] Staphylococci producing exfoliative toxins are the causative agents of staphylococcal scalded skin syndrome (SSSS). ^[18] Staphylococcal scalded skin syndrome (SSSS) describes a spectrum of superficial blistering skin disorders caused by the exfoliative toxins of Staphylococcus aureus  that originates from a focus of infection that may be a purulent conjunctivitis, otitis media, or occult nasopharyngeal infection. ^[19] A biopsy showed a “pauci-inflammatory subcorneal blister compatible with staphylococcal scalded skin syndrome. ^[20] Staphylococcal scalded skin syndrome (SSSS) describes a spectrum of superficial blistering skin disorders caused by the exfoliative toxins of Staphylococcus aureus that originates from a focus of infection that may be a purulent conjunctivitis, otitis media, or occult nasopharyngeal infection. ^[21] Background Treatment of toxin-mediated diseases such as toxic shock syndrome (TSS) and Staphylococcus scalded skin syndrome (SSSS) typically includes adjunctive clindamycin to halt bacterial exotoxin production. ^[22] Staphylococcus aureus can cause exfoliative skin conditions, ranging from localized bullous impetigo (BI) to staphylococcal scalded skin syndrome (SSSS). ^[23] Key words: Infection; Severe skin injury; Staphylococcal scalded skin syndrome; Pseudomonas aeruginosa infection. ^[24] BACKGROUND In August of 2017, Infection Prevention was notified of a single case of Staphylococcus Scalded Skin Syndrome (SSSS) in the Level III Neonatal Intensive Care Unit (NICU), followed by few more cases (in September) of infants with localized blisters and severe exfoliation of the skin. ^[25] This case report describes the clinical course of a child who developed staphylococcal scalded skin syndrome (SSSS) after a burn injury. ^[26] Incompatible initial diagnoses included 4 measles cases, 1 staphylococcal scalded skin syndrome case, 1 cutaneous leishmaniasis case and 1 petechial rash case. ^[27] The skin may be the first clue to certain infections such as herpes simplex virus, syphilis, varicella, cytomegalovirus, fungal infections, and staphylococcal scalded skin syndrome, all of which require immediate testing and some of which may lead to severe sequelae. ^[28] These cases of erythrodermic PF may initially be misdiagnosed as psoriatic erythroderma or staphylococcal scalded skin syndrome (SSSS). ^[29] Purpose: We investigated the clinical features and epidemiology of staphylococcal scalded skin syndrome (SSSS) from year 2006 to 2015 in Changwon city, Korea. ^[30] Forty-two strains were positive for the sey gene, and the positive isolates were from patients with the skin diseases atopic dermatitis and impetigo/staphylococcal scalded skin syndrome (SSSS), with a detection rate of ∼17 to 22%. ^[31] &NA; A sharp increase in staphylococcal scalded skin syndrome (SSSS) cases has been recorded in our settings since 2015, with 31 cases having been documented during the period 2014–2017. ^[32] Background Staphylococcal scalded skin syndrome (SSSS) is a blistering and desquamative skin disease caused by the exfoliative toxins of Staphylococcus aureus. ^[33] Introduction: Staphylococcal scalded skin syndrome is blistering condition characterized by extensive desquamation and cleavage of the superficial layers of the epidermis which has been well characterized in neonates and children below the age of 6 years. ^[34] BACKGROUND The molecular epidemiology of Staphylococcus aureus strains causing staphylococcal scalded skin syndrome (SSSS) in the United States has not been described. ^[35] Background: Staphylococcal scalded skin syndrome (SSSS) is a rare condition, characterized by skin sputtering resulting from the action of exfoliative toxins (ET) produced by Staphylococcus aureus. ^[36] Staphylococcal scalded skin syndrome causes widespread skin denudation primarily in infants < 1 year old. ^[37] Local infections include staphylococcal and streptococcal infections, cellulitis, impetigo, pyoderma, necrotizing fasciitis, scalded skin syndrome (staphylococcal), Fournier gangrene, glanular necrosis, scrotal abscess and even peritonitis. ^[38] Staphylococcal scalded skin syndrome (SSSS) is a blistering skin condition caused by exfoliative toxin-producing strains of S. ^[39] Staphylococcal scalded skin syndrome (4S) is an exfoliative skin disease caused by Staphylococcus aureus toxins. ^[40] Objective To analyze the nursing intervention of staphylococcal scalded skin syndrome in children. ^[41] Akibatnya, istilah-istilah seperti ‘staphylococcal-induced toxic epidermal necrolysis’ dan ‘drug-induced scalded skin syndrome’ menang selama beberapa dekade, tetapi sekarang dipisahkan karena terapi dan prognosisnya berbeda. ^[42] Akibatnya, istilah-istilah seperti ‘staphylococcal-induced toxic epidermal necrolysis’ dan ‘drug-induced scalded skin syndrome’ menang selama beberapa dekade, tetapi sekarang dipisahkan karena terapi dan prognosisnya berbeda. ^[43] Staphylococcal scalded skin syndrome (SSSS) is a disease caused by certain toxigenic strains of Staphylococcus aureus. ^[44] Staphylococcal scalded skin syndrome [SSSS] or Ritter's disease is a vesiculating skin disease most commonly caused by Staphylococcus aureus, a gram positive commensal which asymptomatically colonizes the skin. ^[45] aureus toxins are divided into three categories; (i) superantigens (SAgs) that interfere with receptor function and cause toxic shock syndrome (TSS) or staphylococcal food poisoning (SFP), (ii) exfoliative toxins (ETs) that destroy epidermal barrier functions and cause staphylococcal scalded skin syndrome (SSSS), and (iii) cytotoxins that cause cell lysis. ^[46] This is a case of a three-year-old female who presented with significant dehydration in the setting of a desquamating skin rash diagnosed in our emergency department as staphylococcal scalded skin syndrome. ^[47] Staphylococcal scalded skin syndrome (SSSS) is a major exfoliating skin infection primarily seen in neonates and young children that can lead to serious morbidity. ^[48] Staphylococcal Scalded Skin Syndrome (SSSS) is caused by the exfoliative toxins (ETs) of Staphylococcus aureus. ^[49]

Sensitive Skin Syndrome

Sensitive skin syndrome was associated with normal skin barrier function but lower hydration in infants and children. ^[1] Sensitive skin syndrome has a neuropathic origin, which is why it is frequently associated with irritable bowel syndrome. ^[2] Sensitive skin Syndrome (SSS) is a complex global clinical phenomenon that is defined by the self-reported presence of different sensory perceptions, including tightness, stinging, burning, tingling, pain and pruritus and often without objective signs. ^[3] The assessment of sensitive skin syndrome, characterized by subjective unpleasant sensations, remains a challenge, since there is no international consensus on the best diagnostic tools. ^[4] Irritable bowel and sensitive skin syndromes are common painful conditions that are poorly understood, with alterations of the peripheral (and possibly central) nervous system that lead to a lowering of perception thresholds as the main pathophysiological mechanism. ^[5] Sensitive scalp, one of the most frequent complaints among sensitive skin syndrome, has been described as abnormal and unpleasant sensory reactions of the scalp to environmental stimulus. ^[6] Background: This community-based epidemiological study aimed to estimate the prevalence and risk factors of sensitive skin syndrome (SSS) using the validated Sensitive Scale-10 (SS-10) questionnaire in Hong Kong. ^[7] Introduction: Sensitive Skin Syndrome (SSS) is officially defined as a syndrome with unpleasant sensations like itching, pain, and numbness in response to stimuli that usually do not cause such sensations. ^[8] The AD and sensitive skin syndrome pathogenesis and their management are presented in the article. ^[9] In light of these recent advances, this review proposes to consider the putative role of epidermal keratinocytes in the generation of the unpleasant sensations characteristic of sensitive skin syndrome. ^[10] Sensitive skin syndrome (SSS) is a prevalent skin condition reported globally in most ethnic groups which may occur in any skin location. ^[11]

Peeling Skin Syndrome

Acral peeling skin syndrome (APSS) is a heterogenous group of genodermatoses, manifested by peeling of palmo-plantar skin, occasionally associated with erythema and epidermal thickening. ^[1] 337G > T (acral peeling skin syndrome) and VWF c. ^[2] Loss of TG function is associated with numerous orphan diseases that affect a relatively small number of individuals: loss of FXIIIa (transamidase‐activated form) crosslinking leads to defects in blood coagulation in FXIII deficiency; loss of TG1 and TG5 cross linking leads to defects in epidermal cornification in lamellar ichthyosis and acral peeling skin syndrome, respectively; loss of TG3 crosslinking in hair‐cuticle formation leads to uncombable hair syndrome; the predicted loss of TG6 crosslinking leads to spinocerebellar ataxia‐35; and loss of the structural erythrocyte membrane protein, protein 4. ^[3] Peeling skin syndrome is a heterogeneous group of rare disorders. ^[4] Peeling skin syndrome is a relatively rare clinical case with pathology of apparently normal skin that needs clinical details to reach accurate diagnoses. ^[5] Peeling skin syndrome  is a rare autosomal recessive disorder of cornification that starts either at birth or later in childhood, characterized by widespread painless peeling of the skin in superficial sheets. ^[6] The article analyzes the most significant genodermatoses associated with a high risk of allergic reactions that may occur in the practice of a dermatologist and pediatrician, such as ichthyosis and ichthyosiform dermatoses, Netherton syndrome and other ichthyosiform erythroderma, peeling skin syndrome, SAM syndrome, as well as congenital bullous epidermolysis. ^[7] Peeling skin syndrome (PSS) refers to a large group of disorders featuring detachment of the epidermal uppermost layers. ^[8]

Atopic Skin Syndrome

BACKGROUND Feline atopic skin syndrome (FASS) is a pruritic and inflammatory skin disease commonly encountered in cats. ^[1] CONCLUSION AND CLINICAL RELEVANCE In this review, there was good evidence for the efficacy of systemic glucocorticoids and ciclosporin, and limited evidence for the efficacy of topical glucocorticoids, oclacitinib and allergen-specific immunotherapy in feline atopic skin syndrome. ^[2] Among these disorders is feline atopic skin syndrome (FASS), in which hypersensitivity is typically associated with environmental allergens, although food allergy may coexist. ^[3] CONCLUSIONS AND CLINICAL IMPORTANCE The evidence reviewed was supportive of a role for immunoglobulin (Ig)E in the pathogenesis of both feline atopic skin syndrome (FASS) and asthma, albeit not strongly so. ^[4] Case series summary Two cats with feline atopic skin syndrome (FASS) were included in this case series. ^[5] OBJECTIVES The aim of this study was to assess the efficacy of a new therapeutic regimen of oclacitinib for the control of feline atopic skin syndrome (FASS) and to correlate plasma levels of this drug with clinical effects. ^[6] CONCLUSIONS AND CLINICAL IMPORTANCE The term "Feline Atopic Syndrome" (FAS) is proposed to encompass allergic diseases of the skin, gastrointestinal tract and respiratory tract, and "Feline atopic skin syndrome" (FASS) proposed to describe allergic skin disease associated with environmental allergies. ^[7]

Stiff Skin Syndrome

Stiff skin syndrome (SSS) is a rare, scleroderma‐like condition that is commonly characterised by stony hard skin and limited joint mobility, in the absence of visceral involvement or immunologic abnormalities. ^[1] Their rarest manifestations are considered – stiff skin syndrome – Stiffsyndrome and congenital fascial dystrophy. ^[2] In this case, in view of fibrotic arthropathy, a differential diagnosis was made with deep morphea and stiff skin syndrome. ^[3] A subset of missense mutations within TB4 cause stiff skin syndrome (SSS), a rare autosomal dominant form of scleroderma. ^[4]

Foot Skin Syndrome

The toxicity included hypertension, fatigue and hand-foot skin syndrome in grade1-2, which were controllable and well tolerated. ^[1] He additionally developed fatigue, hypertension, diarrhoea, hand-foot skin syndrome, abnormal serum apoliporotein A, decreased thyroxine and elevated thyroid stimulating hormone during treatment with catequentinib and developed abdominal pain and fatigue during treatment with rivoceranib for giant delayed pulmonary metastasis of osteosarcoma [routes and durations of treatments to reactions onsets not stated; not all outcomes stated]. ^[2] The most common grade 3/4 adverse events were hand-foot skin syndrome [three (13. ^[3]

Characteristic Skin Syndrome

The boy developed a characteristic skin syndrome, which was associated with the formation of skin blisters, mucosal erosions. ^[1] The disease had typical moderate course, aggravated with characteristic skin syndrome. ^[2]

Paraneoplastic Skin Syndrome

1,2 Malignant acanthosis nigricans is a rare paraneoplastic skin syndrome that presents with sudden onset of hyperpigmented velvety plaques, most commonly in intertriginous areas. ^[1] A paraneoplastic skin syndrome should be considered in persistent skin disease not responding to treatment and starting in middle-aged patients with B symptoms. ^[2]

Toasted Skin Syndrome

EAI, also known as “toasted skin syndrome” or “fire stains”, is a localized skin lesion, manifesting itself as reticular hyperpigmentation, dark erythema, epidermal atrophy, and telangiectasias (1). ^[1] Erythema ab igne, also known as toasted skin syndrome, is an acquired asymmetric hyperpigmented dermatosis that is caused by repeated exposure to moderate heat or infrared radiation. ^[2]