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Silico Analysis sentence examples within transcription factor binding
Via in silico analysis, we identified transcription factor binding sites that could potentially influence methylation-dependent gene transcription.
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The in silico analysis revealed that the rs968697 polymorphism in the promoter region of the HMGA2 gene could influence transcription factor binding, including ATF6, DBP, CDPCR3, DR3, NRSF, PAX8, PPARA, SZF11, TAXCREB and POLR2A.
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Silico Analysis sentence examples within cis acting regulatory
Several essential core cis-acting elements and numerous light-responsive cis-acting regulatory elements were identified in Ppd-D1b promoter by the in-silico analysis.
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In silico analysis showed that various development-associated, phytohormone-responsive, and stress-related cis-acting regulatory elements were enriched in the promoter regions of BnMYB-related genes.
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Silico Analysis sentence examples within basic leucine zipper
Initially, we performed an in silico analysis to identify potential transcription binding sites for the basic leucine zipper 62 transcription factor (bZIP62 TF) in the target branching related genes.
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Initially, we performed an in silico analysis to identify potential binding sites for the basic leucine zipper 62 transcription factor (AtbZIP62 TF) in the promoter of the target genes, and constructed their protein–protein interaction networks.
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Silico Analysis sentence examples within absorption distribution metabolism
In silico analysis of the major active chemical constituents (Oroxylin A, Baicalein and Chrysin) of OIE indicated that OIE has a favorable absorption, distribution, metabolism and excretion (ADME) profile.
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In addition, in silico analysis of these three biomolecules was performed to predict parameters of absorption, distribution, metabolism and excretion.
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Silico Analysis sentence examples within amino acid substitution
The R545H missense variant has been found at very low allelic frequency in public databases, and in silico analysis showed that this amino acid substitution is predicted to have a damaging role.
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With the help of in-silico analysis of a hypothetical R-protein (Hyp-R) in sesame, we tested the hypothesis that how amino acid substitution in the conserved P-loop motif can affect the interaction between ligand and NB-ARC domain.
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Silico Analysis sentence examples within silico analysis revealed
Silico Analysis sentence examples within silico analysis showed
In silico analysis showed that they grouped into 16 different sequence types and 17 serotypes; the serotypes most frequently identified were O116:H21 and O168:H8 (13% each).
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In silico analysis showed that the variant destabilizes the hydrophobic core and allosterically affects the enzyme activity.
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Silico Analysis sentence examples within silico analysis predicted
Silico Analysis sentence examples within silico analysis suggested
Silico Analysis sentence examples within silico analysis indicated
In silico analysis indicated pathogenic potentials and clinical interpretations of the detected variants.
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In silico analysis indicated that toll-like receptor (TLR)-9 was significantly overexpressed, and that miRNA (hsa-miR-30a-5p) was downregulated in sorafenib-resistant HCC cells, which modulated HCC cell proliferation, oxidative stress, and apoptosis.
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Silico Analysis sentence examples within silico analysis identified
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Silico Analysis sentence examples within silico analysis suggest
Transient transfections of Hmgcr-promoter mutants and in silico analysis suggest altered binding of Runx3 and Srebf1 across A-405G site.
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Finally, the in-silico analysis suggests that miR-30b-5p is predicted to target 62 genes involved in different signaling pathways involved in vascular remodeling.
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Silico Analysis sentence examples within silico analysis predict
An in-silico analysis predicts that members of this group harbor a highly conserved and structured Myb-DBD and a large portion of intrinsically disordered residues.
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In silico analysis predicts the mutated protein hinders the dimerization of SEPT6 coiled coils in both parallel and antiparallel arrangements, which could in turn impair filament formation.
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Silico Analysis sentence examples within silico analysis provide
This in silico analysis provides information about functional nucleotide variants that have an impact on the ACE2 protein structure and function and therefore susceptibility to SARS-CoV-2.
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Conclusions Overall, our in silico analysis provides a framework to identify novel and specific TSAs for the development of new CAR-T and antibody-based therapies in BC.
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Silico Analysis sentence examples within silico analysis followed
In face of the urgent demand for effective drugs to treat Covid-19, we have searched for candidate compounds using a drug repurposing approach based on in silico analysis followed by biological validation.
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In silico analysis followed by a yeast two-hybrid screen-identified ChiLCV-CP as the interacting partner of the ChiLCB-βC1 protein.
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Silico Analysis sentence examples within silico analysis demonstrated
In silico analysis demonstrated that the E142A and M279R mutations in NDUFAF5 protein significantly perturbed the normal conformation of the protein due to alterations in the hydrogen bonding patterns around the evolutionarily conserved catalytic domains, leading to its loss of function in the early stage of mitochondrial complex I assembly.
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Microarray and in silico analysis demonstrated that PBDE-47 can induce some epigenetic effects in M(LPS) THP-1 cells modulating the expression of a set of intracellular miRNAs involved in biological pathways regulating the expression of estrogen-mediated signaling and immune responses with particular reference to M1/M2 differentiation.
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Silico Analysis sentence examples within silico analysis show
Silico Analysis sentence examples within silico analysis indicate
Correspondingly, in silico analysis indicates that plasminogen is recruitable by the viral neuraminidase for proteolytic activation due to the loss of a strongly conserved N-glycosylation site at position 130.
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In silico analysis indicates that 340 has a higher binding affinity against Mpro than darunavir with ΔGbinding values of −43.
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Silico Analysis sentence examples within silico analysis support
Enzyme kinetics of two putative methemoglobin reductases with methemoglobins as substrates and in silico analysis support interaction between the hemoglobins and the two reduction partners as also observed in vitro.
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Previous reports and our in-silico analysis support the association of DCM phenotype and impaired tissue angiogenesis.
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Silico Analysis sentence examples within silico analysis also
Silico Analysis sentence examples within silico analysis tool
This variant is predicted to be deleterious by multiple in silico analysis tools, moreover the Arg87 amino acid nearly is invariant among eight species.
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We detected 11 variations having conflicting interpretations in databases and 30 novel variations, predicted as likely pathogenic via insilico analysis tools which further evaluations are needed.
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Silico Analysis sentence examples within silico analysis reveal
Silico Analysis sentence examples within silico analysis method
Materials & methods: Five different bioinformatics tools were used for predicting GPI-anchored proteins; we considered as GPI-anchored proteins those detected by at least two in silico analysis methods.
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This review focuses on the methods of discovery of food-derived DPP-IV inhibitory peptides, including fractionation and purification approaches, in silico analysis methods, in vivo studies, and the bioavailability of these food-derived peptides.
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Silico Analysis sentence examples within silico analysis demonstrate
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Silico Analysis sentence examples within silico analysis allowed
We conclude that, in silico analysis allowed for the identification of natural Leishmania epitopes in humans, and also STI41 and STI46 peptides could be epitopes that lead to a cellular immune response directed at parasite control.
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FINDINGS
In silico analysis allowed to design a "screening" assay for detection of mcr-1/2/6, mcr-3, mcr-4, mcr-5, mcr-7, mcr-8 and mcr-9/10 paired with an internal control assay to discount inhibition.
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Silico Analysis sentence examples within silico analysis presented
Silico Analysis sentence examples within silico analysis pipeline
We developed a new in silico analysis pipeline for the previously described primer-extension-mediated sequencing assay to comprehensively characterize CRISPR-Cas9-induced DSB repair outcomes in human or mouse cells.
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We developed a new in silico analysis pipeline for the previously described primer-extension-mediated sequencing assay to comprehensively characterize CRISPR–Cas9-induced DSB repair outcomes in human or mouse cells.
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Functional in silico analysis found that DNAMeFourLncSig-related mRNAs were mainly enriched in cell differentiation, tissue development and immune-related pathways.
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Binding of FA to the mouse 5-HT1A receptor was evaluated by in silico analysis.
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Previously in silico analysis of human PL scramblases, predicted the presence of an uncharacterized cholesterol-binding domain spanning partly in the transmembrane helix as well as in the adjacent extracellular coil.
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In silico analysis provided an explanation for E484K immune evasion.
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