Introduction to Sars Cov 2 Surveillance
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This will require coordinated global SARS-CoV-2 surveillance to link genotypes to phenotypes, potentially using the WHO’s global influenza surveillance program as a guide.
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Background To achieve higher effectiveness in population-based SARS-CoV-2 surveillance and to reliably predict the course of an outbreak, screening, and monitoring of infected individuals without major symptoms (about 40% of the population) will be necessary.
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SARS-CoV-2 surveillance is important to controlling widespread transmission and contains the disease in small peaks.
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Petersburg, Russia and combines them with other SARS-CoV-2 surveillance data.
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Conclusion
The incidence of SARS-CoV-2 was high among outpatients with a significant proportion of presymptomatic carriers, so it is necessary increasing testing and continue the SARS-CoV-2 surveillance with a better description of signs and symptoms; in this regard, were identified three symptomatic profiles that could help in the diagnose of COVID-19.
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This case shows the risk for introduction of SARS-CoV-2 variants from indirect flights and the need for continued SARS-CoV-2 surveillance.
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CONCLUSIONS
This study highlights that co-circulating respiratory viruses can distort SARS-CoV-2 surveillance.
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Our results lay the foundation for more extensive SARS-CoV-2 surveillance in Ghana and the West African sub-region, including deploying rapid antigen test kits in concert to determine the actual infection burden since antibody development lags infection.
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Our results provided molecular evidence for the source of COVID-19 outbreak in Beijing XFD, which highlights new targets for SARS-CoV-2 surveillance for the public health.
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Detecting and monitoring novel variants is essential in SARS-CoV-2 surveillance.
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Wastewater testing demonstrated the utility of school building-level SARS-CoV-2 surveillance.
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As the second wave reaches East Asia and the Pacific, it becomes more obvious that additional SARS-CoV-2 surveillance is needed to track recent shifts in the pandemic, rates of increase, and persistence.
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Methods
: We initiated SARS-CoV-2 surveillance in 18 secondary schools across six regions in September 2020.
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Wastewater-based epidemiology/wastewater surveillance has been a topic of significant interest over the last year due to its application in SARS-CoV-2 surveillance to track prevalence of COVID-19 in communities.
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Here we described our experience doing SARS-CoV-2 surveillance at Waorani communities from June to September 2020 on the Amazonia, showing that self isolation strategies failed to contain COVID-19 spread.
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Methods Public Health England initiated SARS-CoV-2 surveillance in 18 secondary schools across six regions in September 2020.
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Findings will inform the choice of the most effective, acceptable and affordable strategy for SARS-CoV-2 surveillance, with the most effective and cost-effective strategy becoming part of the local public health department’s current routine health surveillance activities.
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Materials and Methods We developed a sequencing and bioinformatics workflow for molecular epidemiological SARS-CoV-2 surveillance using excess clinical specimens collected under an institutional review board exempt protocol at Joint Base San Antonio, Lackland AFB.
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Conclusion: Overall, this simple direct RT-PCR approach can be utilized as a qualitative diagnostic tool for emergency SARS-CoV-2 surveillance in countries with limited resources and may help laboratories to continue testing and at greater frequency despite supply shortages, although with delay in cycle threshold value in comparison with indirect RT-PCR.
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Conclusions: This study highlights that co-circulating respiratory viruses can disrupt SARS-CoV-2 surveillance.
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Saliva can be a surrogate for SARS-CoV-2 surveillance, particularly in social settings such as hospitals.
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In a context of SARS-CoV-2 surveillance needed proper and fast assessment of epidemiological clusters from large amount of samples, the present manuscript proposes a workflow for identifying accurately the PANGOLIN lineages of SARS-CoV-2 samples and building of discriminant minimum spanning trees (MST) bypassing the usual time consuming phylogenomic inferences based on multiple sequence alignment (MSA) and substitution model.
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Interpretation: Our validation study encourages the use of local antibody tests for population-based SARS-CoV-2 surveillance and sets the reference for the seroprevalence correction.
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These limitations result in SARS-CoV-2 surveillance blackouts across several countries.
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As hospitals and public facilities apply varying degrees of restrictions and regulations, it is important to provide multiple methodological options to enable environmental SARS-CoV-2 surveillance under different conditions.
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This review article precisely provides the extensive scientific advancement and intensive look of basic principles and implementation of biosensors in SARS-CoV-2 surveillance, especially for human health.
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Wastewater-based epidemiology is a topic of significant interest over the last year due to the application of SARS-CoV-2 surveillance to track incidence rates of COVID-19 in communities.
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It becomes more obvious that additional SARS-CoV-2 surveillance is needed at the local level to track recent shifts in the pandemic, rates of increase, and persistence.
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Characterizing global genomic surveillance, sequencing coverage, the extent of publicly available genomic data coupled with traditional epidemiologic data can provide evidence to inform SARS-CoV-2 surveillance and control strategies.
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The SARS-CoV-2 surveillance program among migrants arriving to Sicily via the Mediterranean Sea, made by the combination of clinical examination and molecular testing, has been integrated by full-genome sequencing strains using the NGS technology from the last week of February.
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This study demonstrates that self-collected nasal-swab has shown to be a valid and well tolerated procedure to SARS-CoV-2 surveillance in a healthcare system.
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Simple group testing designs to improve SARS-CoV-2 surveillance in resource-constrained settings are identified using modeling and experimental data.
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Interpretation
In a large-scale SARS-CoV-2 surveillance programme in Madurai, India, we identified equal risk of asymptomatic infection among children, teenagers, and working-age adults, and increasing risk of infection and death associated with older age and comorbidities.
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Routine SARS-CoV-2 surveillance in the Western Cape region of South Africa (January-August 2021) found a reduced PCR amplification efficiency of the RdRp gene target of the Seegene, Allplex 2019-nCoV diagnostic assay when detecting the Delta variant.
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On April 23, 2020, FH implemented SARS-CoV-2 surveillance among all consecutive admissions not suspected of COVID-19, all patients scheduled for elective procedures and deliveries, and all asymptomatic patients with known exposures.
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All three assays were assessed using a panel of 1999 paired serum and oral fluids from children and adults participating in national primary school SARS-CoV-2 surveillance studies during and after the first and second pandemic wave in the UK.
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Detecting and monitoring novel variants is essential in SARS-CoV-2 surveillance.
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Methods Public Health England (PHE) invited secondary schools in six regions (East and West London, Hertfordshire, Derbyshire, Manchester and Birmingham) to participate in SARS-CoV-2 surveillance during the 2020/21 academic year.
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Wastewater based epidemiology (WBE) has been successfully applied for SARS-CoV-2 surveillance at the city and building levels.
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The aim of this work was to evaluate if rivers could be used for SARS-CoV-2 surveillance to support health authorities.
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These findings confirmed the effectiveness of SWBS for non-invasive and dynamic SARS-CoV-2 surveillance.
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We investigated whether repeated non-mandatory RT-PCR SARS-CoV-2 surveillance of NH staff and visitors reduces COVID-19 incidence rates in NH residents and allows to reduce visiting restrictions.
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Although many research groups have already reported SARS-CoV-2 surveillance in untreated wastewater, only few studies evaluated the implications of the pandemic on the use of chemicals by influent wastewater analysis.
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The high diversity of sequences observed over two months in Frankfurt am Main highlights the persisting need for continuous SARS-CoV-2 surveillance using full-genome sequencing, particularly in cities with international airport connections.
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The findings reported in this paper contributed to the field of wastewater-based epidemiology dealing with SARS-COV-2 surveillance for developing countries where proper sewage system is absent and highlighting some of the challenges associated with this approach in such settings.
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As the second wave reaches East Asia and the Pacific, it becomes more evident that additional SARS-CoV-2 surveillance is needed to track recent shifts, rates of increase, and persistence associated with the pandemic.
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Here, we propose a proof-of-concept pooling strategy for antigen testing that would significantly expand SARS-CoV-2 surveillance, especially for low-to-middle income countries, schools, and workplaces.
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This finding demonstrates the importance of real-time SARS-CoV-2 surveillance to better inform public health responses.
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Our findings highlight the need to maintain SARS-CoV-2 surveillance in these high-risk settings beyond the current COVID-19 mass vaccination campaign, and advocate for a booster vaccine dose prior to the next winter season.
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Conclusion
Our data suggest air sampling may be an important SARS-CoV-2 surveillance technique, especially for buildings with congregant living settings (dorms, correctional facilities, barracks).
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The results of the PHE Manchester SARS-CoV-2 surveillance during the first wave are presented.
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