Introduction to Salt Transporter

Sentence Examples

Discover more insights into Salt Transporter

Keywords frequently search together with Salt Transporter

Narrow sentence examples with built-in keyword filters

Salt Transporter sentence examples within apical sodium dependent

apical sodium dependent

Untreated NASH animals had significantly reduced biliary secretion of BA and increased fecal excretion of BA via decreased apical sodium-dependent bile salt transporter (Asbt)-mediated reabsorption.

Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis

apical sodium dependent

Reabsorption of conjugated bile salts in the ileum is mediated by the apical sodium-dependent bile salt transporter ASBT (ileum sodium-dependent bile salt transporter) [6].

Targeting the ileal bile salt transporter in the treatment of non-alcoholic fatty liver disease

More apical sodium dependent sentences More Sentences

Salt Transporter sentence examples within Bile Salt Transporter

Bile Salt Transporter

Untreated NASH animals had significantly reduced biliary secretion of BA and increased fecal excretion of BA via decreased apical sodium-dependent bile salt transporter (Asbt)-mediated reabsorption.

Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis

Bile Salt Transporter

Transporters of drug, heme, lipid, and nucleus were significantly increased, while bile acid and bile salt transporters were decreased (Supplementary Fig.

Pathological features of COVID-19-associated liver injury—a preliminary proteomics report based on clinical samples

More Bile Salt Transporter sentences More Sentences

More Salt Transporter sentence examples
10.3390/ijms22126468

Untreated NASH animals had significantly reduced biliary secretion of BA and increased fecal excretion of BA via decreased apical sodium-dependent bile salt transporter (Asbt)-mediated reabsorption.

Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis

More Salt Transporter sentence examples
10.1038/s41392-020-00406-1

Transporters of drug, heme, lipid, and nucleus were significantly increased, while bile acid and bile salt transporters were decreased (Supplementary Fig.

Pathological features of COVID-19-associated liver injury—a preliminary proteomics report based on clinical samples

More Salt Transporter sentence examples
10.1007/s12072-021-10134-5

Reabsorption of conjugated bile salts in the ileum is mediated by the apical sodium-dependent bile salt transporter ASBT (ileum sodium-dependent bile salt transporter) [6].

Targeting the ileal bile salt transporter in the treatment of non-alcoholic fatty liver disease

More Salt Transporter sentence examples
10.1016/j.biochi.2021.03.016

glutathione), through the bile salt transporter BSEP/ABCB11 and the organic anion transporter MRP2/ABCC2, respectively, are considered to be the major osmotic driving forces for water secretion into bile canaliculi mainly via aquaporin-8 (AQP8) channels.

Aquaporin gene transfer for hepatocellular cholestasis.

More Salt Transporter sentence examples
10.1124/jpet.120.000449

These novel fluorescent probes were able to block substrate transport in a concentration-dependent manner of NTCP, OATP1B1, OATP1B3, OATP2B1, BSEP, and intestinal apical sodium-dependent bile salt transporter (ASBT).

Characterization of Novel Fluorescent Bile Salt Derivatives for Studying Human Bile Salt and Organic Anion Transporters

More Salt Transporter sentence examples
10.1111/liv.14967

As bulevirtide binds the same receptor of bile salt transporter, an increase in total bile acid has been reported as the most frequent adverse event, which was usually transient and asymptomatic.

Bulevirtide for treatment of patients with HDV infection and compensated cirrhosis: A (huge?) step in the right direction

More Salt Transporter sentence examples
10.1021/acs.jcim.0c00950

Cholestatic liver injury is frequently associated with drug inhibition of bile salt transporters, such as the bile salt export pump (BSEP).

Machine Learning Models to Predict Inhibition of the Bile Salt Export Pump

More Salt Transporter sentence examples
10.1186/s12929-020-00706-2

Background The bile salt export pump (BSEP) is a pivotal apical/canalicular bile salt transporter in hepatocytes that drives the bile flow.

The ESCRT-III molecules regulate the apical targeting of bile salt export pump

More Salt Transporter sentence examples
10.1152/ajprenal.00142.2018

These effects are independent of changes in food intake and result from a coordinated downregulation of water channel aquaporin-2 (AQP2) and salt transporter (Na+-K+-Cl- cotransporter 2; NKCC2) in the collecting duct and medullary thick ascending limb, respectively.

Adenine acts in the kidney as a signaling factor and causes salt- and water-losing nephropathy: early mechanism of adenine-induced renal injury.

More Salt Transporter sentence examples
10.31661/jbpe.v9i1feb.616

The gene for PFIC1 has been mapped on a 19-cM region of 18q21-q22, and a gene defect in ATP8B1 can cause deregulations in bile salt transporters through decreased expression and/or activity of FXR.

In-silico Evaluation of Rare Codons and their Positions in the Structure of ATP8b1 Gene

More Salt Transporter sentence examples
10.1002/14651858.CD009841.pub3

BACKGROUND Cystic fibrosis (CF) is the commonest inherited life-shortening illness in white populations, caused by a mutation in the gene that codes for the cystic fibrosis transmembrane regulator protein (CFTR), which functions as a salt transporter.

Potentiators (specific therapies for class III and IV mutations) for cystic fibrosis.

More Salt Transporter sentence examples
10.1007/s00204-019-02582-8

This was accompanied by transcriptional deregulation of hepatic bile salt transporters like Abcb11 or Abcc1.

The pyrrolizidine alkaloid senecionine induces CYP-dependent destruction of sinusoidal endothelial cells and cholestasis in mice

More Salt Transporter sentence examples
10.14814/phy2.14280

With the knowledge that WNK proteins are Cl− sensors, and are a part of the WNK/SPAK/NCC signaling cascade which regulates the NCC, the main salt transporter in the distal nephron, we examined the effect of serum K+ on the ([Cl−]i) and, in turn its effect on the WNK4 signaling pathway in a “modified HEK 293T” cell line.

Modified HEK cells simulate DCT cells in their sensitivity and response to changes in extracellular K

More Salt Transporter sentence examples
10.1016/j.tiv.2019.01.003

In HEK293 cells overexpressing bile salt transporters, we observed that p-cresyl sulfate inhibited Na+-taurocholate cotransporting polypeptide (NTCP)-mediated uptake of taurocholic acid (TCA), whereas organic anion-transporting polypeptide 1B1 (OATP1B1)-mediated TCA uptake was increased.

Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity.

More Salt Transporter sentence examples
10.31661/JBPE.V9I1FEB.616

The gene for PFIC1 has been mapped on a 19-cM region of 18q21-q22, and a gene defect in ATP8B1 can cause deregulations in bile salt transporters through decreased expression and/or activity of FXR.

In-silico Evaluation of Rare Codons and their Positions in the Structure of ATP8b1 Gene.

Learn more from Salt Transporter

Keywords related to Salt

Keywords related to Transporter

Salt Transporter
Encyclopedia

What is/are Salt Transporter?

Salt Transporter - Untreated NASH animals had significantly reduced biliary secretion of BA and increased fecal excretion of BA via decreased apical sodium-dependent bile salt transporter (Asbt)-mediated reabsorption. [1] Transporters of drug, heme, lipid, and nucleus were significantly increased, while bile acid and bile salt transporters were decreased (Supplementary Fig. [2] Reabsorption of conjugated bile salts in the ileum is mediated by the apical sodium-dependent bile salt transporter ASBT (ileum sodium-dependent bile salt transporter) [6]. [3] glutathione), through the bile salt transporter BSEP/ABCB11 and the organic anion transporter MRP2/ABCC2, respectively, are considered to be the major osmotic driving forces for water secretion into bile canaliculi mainly via aquaporin-8 (AQP8) channels. [4] These novel fluorescent probes were able to block substrate transport in a concentration-dependent manner of NTCP, OATP1B1, OATP1B3, OATP2B1, BSEP, and intestinal apical sodium-dependent bile salt transporter (ASBT). [5] As bulevirtide binds the same receptor of bile salt transporter, an increase in total bile acid has been reported as the most frequent adverse event, which was usually transient and asymptomatic. [6] Cholestatic liver injury is frequently associated with drug inhibition of bile salt transporters, such as the bile salt export pump (BSEP). [7] Background The bile salt export pump (BSEP) is a pivotal apical/canalicular bile salt transporter in hepatocytes that drives the bile flow. [8] These effects are independent of changes in food intake and result from a coordinated downregulation of water channel aquaporin-2 (AQP2) and salt transporter (Na+-K+-Cl- cotransporter 2; NKCC2) in the collecting duct and medullary thick ascending limb, respectively. [9] The gene for PFIC1 has been mapped on a 19-cM region of 18q21-q22, and a gene defect in ATP8B1 can cause deregulations in bile salt transporters through decreased expression and/or activity of FXR. [10] BACKGROUND Cystic fibrosis (CF) is the commonest inherited life-shortening illness in white populations, caused by a mutation in the gene that codes for the cystic fibrosis transmembrane regulator protein (CFTR), which functions as a salt transporter. [11] This was accompanied by transcriptional deregulation of hepatic bile salt transporters like Abcb11 or Abcc1. [12] With the knowledge that WNK proteins are Cl− sensors, and are a part of the WNK/SPAK/NCC signaling cascade which regulates the NCC, the main salt transporter in the distal nephron, we examined the effect of serum K+ on the ([Cl−]i) and, in turn its effect on the WNK4 signaling pathway in a “modified HEK 293T” cell line. [13] In HEK293 cells overexpressing bile salt transporters, we observed that p-cresyl sulfate inhibited Na+-taurocholate cotransporting polypeptide (NTCP)-mediated uptake of taurocholic acid (TCA), whereas organic anion-transporting polypeptide 1B1 (OATP1B1)-mediated TCA uptake was increased. [14] The gene for PFIC1 has been mapped on a 19-cM region of 18q21-q22, and a gene defect in ATP8B1 can cause deregulations in bile salt transporters through decreased expression and/or activity of FXR. [15]

apical sodium dependent

Untreated NASH animals had significantly reduced biliary secretion of BA and increased fecal excretion of BA via decreased apical sodium-dependent bile salt transporter (Asbt)-mediated reabsorption. [1] Reabsorption of conjugated bile salts in the ileum is mediated by the apical sodium-dependent bile salt transporter ASBT (ileum sodium-dependent bile salt transporter) [6]. [2] These novel fluorescent probes were able to block substrate transport in a concentration-dependent manner of NTCP, OATP1B1, OATP1B3, OATP2B1, BSEP, and intestinal apical sodium-dependent bile salt transporter (ASBT). [3]

Bile Salt Transporter

Untreated NASH animals had significantly reduced biliary secretion of BA and increased fecal excretion of BA via decreased apical sodium-dependent bile salt transporter (Asbt)-mediated reabsorption. [1] Transporters of drug, heme, lipid, and nucleus were significantly increased, while bile acid and bile salt transporters were decreased (Supplementary Fig. [2] Reabsorption of conjugated bile salts in the ileum is mediated by the apical sodium-dependent bile salt transporter ASBT (ileum sodium-dependent bile salt transporter) [6]. [3] glutathione), through the bile salt transporter BSEP/ABCB11 and the organic anion transporter MRP2/ABCC2, respectively, are considered to be the major osmotic driving forces for water secretion into bile canaliculi mainly via aquaporin-8 (AQP8) channels. [4] These novel fluorescent probes were able to block substrate transport in a concentration-dependent manner of NTCP, OATP1B1, OATP1B3, OATP2B1, BSEP, and intestinal apical sodium-dependent bile salt transporter (ASBT). [5] As bulevirtide binds the same receptor of bile salt transporter, an increase in total bile acid has been reported as the most frequent adverse event, which was usually transient and asymptomatic. [6] Cholestatic liver injury is frequently associated with drug inhibition of bile salt transporters, such as the bile salt export pump (BSEP). [7] Background The bile salt export pump (BSEP) is a pivotal apical/canalicular bile salt transporter in hepatocytes that drives the bile flow. [8] The gene for PFIC1 has been mapped on a 19-cM region of 18q21-q22, and a gene defect in ATP8B1 can cause deregulations in bile salt transporters through decreased expression and/or activity of FXR. [9] This was accompanied by transcriptional deregulation of hepatic bile salt transporters like Abcb11 or Abcc1. [10] In HEK293 cells overexpressing bile salt transporters, we observed that p-cresyl sulfate inhibited Na+-taurocholate cotransporting polypeptide (NTCP)-mediated uptake of taurocholic acid (TCA), whereas organic anion-transporting polypeptide 1B1 (OATP1B1)-mediated TCA uptake was increased. [11] The gene for PFIC1 has been mapped on a 19-cM region of 18q21-q22, and a gene defect in ATP8B1 can cause deregulations in bile salt transporters through decreased expression and/or activity of FXR. [12]