Introduction to Rhupus Syndrome

What is/are Rhupus Syndrome?

Rhupus Syndrome - Rhupus syndrome is a rare and incompletely described autoimmune entity in which the same patient sequentially develops symptoms both of Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE). ^[1] Rhupus syndrome was diagnosed. ^[2] Rhupus syndrome: Assessment of its prevalence and its clinical and instrumental characteristics in a prospective cohort of 103 SLE patients. ^[3] Rhupus syndrome is a clinical condition characterized by a combination of the clinical and immunologic features of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) (1). ^[4] Such condition defines the Rhupus syndrome, which is a rare overlapping syndrome. ^[5] Organ involvement in Rhupus syndrome is relatively rare. ^[6] Rhupus syndrome is a rare clinical condition, characterized by overlap of SLE and RA. ^[7] However, to date, no consensus exists on how to define the rhupus syndrome. ^[8] Rhupus syndrome, a rare entity, is the co-existence of systemic lupus erythematosus (SLE) with rheumatoid arthritis (RA). ^[9] Interstitial lung disease (ILD) is seen in 17% of patients with Rhupus syndrome. ^[10] To the Editor,Occasionally, we encounter patients who develop overlapping features of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), which is termed as ‘rhupus syndrome’ [1]. ^[11] In less than 15% of patients, joints may be more severely affected by deforming (Jaccoud's arthropathy) and/or erosive arthropathy (Rhupus syndrome). ^[12]