Introduction to Review Current

Finally, we review current trends and suggest future research directions based on the existing challenges.

Method:  We review current research on open innovation in general and especially in the Brazilian setting to develop a framework for studying this phenomenon and to suggest future research directions.

We aim to review current knowledge of the JAK/STAT signaling pathway and its role in immune-mediated skin diseases.

We aim to review current knowledge of the JAK/STAT signaling pathway and its role in immune-mediated skin diseases.

No review currently exists to establish the variety of technologies and their uses in undergraduate medical education when patients and/or carers are involved.

In this paper, we review current literature and propose some ideas that can help incorporate oncology, and specifically radiation oncology, into undergraduate medical education.

Aim: To review current literature and standard practices in various techniques of sentinel node biopsy for staging theaxilla for treating early breast cancer The purpose is to provide evidence based recommendation as guidanceplatform for optimal true sentinel node retrieval irrespective of surgeon expertise Background: Axillary conservationis the way forward after game changing trials like ACOSOG Z0011, surrogate trials like IBCSG,AMAROS,ALMANAC, ongoing POSNOC, and newbie ATNEC have progressively or plan to decrease the need tounnecessarily fiddle with the axilla thereby increasing the chances of arm related and other morbidities Axillarysentinel node biopsy entails retrieval of first draining lymph node in the breast-axilla pathway to plan treatment inbreast cancer by appropriate staging of axilla Current standard is the utilisation of double agent technique withradioactive isotope and blue dye injection to decrease false negative rates for true sentinel node retrieval Noveltechniques like magnetic and infrared tracing are still being investigated for validation Method: PMC, Medline,EMBASE, PubMed and Cochrane library searched for clinical trials, randomised trials, systematic reviews and meta-analysis on techniques of axillary sentinel node biopsy in early breast cancer This covered the last 25 yearsliterature on the topic Results: The search yielded 197 publications which were subjected to a meticulous reviewand narrowed to a select pertinent body of evidence to extrapolate suggested guidance rationally, the bibliography of which is provided at the end Conclusion: Single agent preferably radioisotope for lymphatic mapping isrecommended in palpable and good biology tumours Use of single agent blue dye can be standardised in axillary tail tumours It is also recommended as being effective when isotope mapping is logistically not feasible or duringpandemics like COVID 19 where looming infrastructure challenges are prevalent Dual agent technique should beconsidered in previously treated breast and axilla, neoadjuvant chemotherapy cohort, bad tumour biology, high BMIand macromastia groups for true nodal retrieval Optimal number of nodes taken out should not be more than three(n=3) Lower axillary sampling of not more than 3 nodes is recommended for troubleshooting with any localisingagent technique Triple site injection at peri-tumoural, subcutaneous and sub areolar regions and larger volume ofblue dye agent injection of up to 8mls increases the localisation success in the dual technique group for lymphaticmapping Magnetic tracing can be used as an adjunct to either single agent radioactive isotope or blue dye (RI/BD)technique when there is failure to localise the sentinel node.

Purpose of review Current standard for HER2+ early breast cancer patients includes chemotherapy and trastuzumab for 1 year.

We review current dietary recommendations for fat intake by CKD patients and suggest potential nutritional interventions by emphasizing dietary lipids that might improve the blood lipid profile and reduce cardiovascular risk in CKD.

We review current strategies that target MDSC-mediated immunosuppression to enhance NK cell cytotoxic antitumor activity.

To review current US, as well as international, guidelines for anticoagulant reversal agents in patients on VKAs or DOACs presenting with GI bleeding prior to endoscopy, guideline-based management of coagulation defects, timing of endoscopy, and recommendations for resumption of anticoagulant therapy following hemostasis.

Purpose: To review current literature on texting as a sustainable intervention of case management in the outpatient setting.

Here, we systematically review current points involved in regulatory mechanisms and the multidimensional roles of pyroptosis in several metabolic diseases and the tumor microenvironment.

DATA SOURCES The Preferred Reporting Items for Systematic Reviews and Meta-analyses was used to systematically review current literature in a single database from 2009 to the date of search (July 2019).

We also review current state-of-the-art biology, histopathology, computation, and genomics in the setting of the stroma.

Last, we also review current and potential new therapeutic strategies based on immunomodulation.

We summarize and critically review current knowledge on the molecular aspects of cell-death regulation during animal coronaviruses infection and the viral–host interactions to this process.

Purpose The purpose of this study is to critically review current studies on job crafting to identify contextual factors related to employees’ job crafting and to integrate the findings to help organizations improve employees’ job crafting.

In this article we briefly review current influenza vaccines, address safety concerns and the need for newer influenza vaccines of higher efficacy, and discuss efforts to create broadly protective, universal influenza vaccines.

We report two cases of this extremely rare association of cholinergic urticaria and acquired generalized hypohidrosis, and briefly review current knowledge with regard to classification, ethiopathogenesis and therapeutic options.

Based on the results of the survey and ongoing discussions among medical students, residents, and faculty leaders, the authors review current recruitment efforts and new ideas.

The authors review current literature to help guide surgeon decision making when utilizing navigation.

Here we comprehensively review current knowledge on B cell mechanisms in immune mediated liver diseases, exploring disease pathogenesis, B cell therapies, and novel treatment targets.

Here we comprehensively review current and potential applications of endophytes in the agricultural, pharmaceutical, and industrial sectors.

Here I review current structure–function information on the viral spike proteins and the membrane fusion process to provide plausible explanations for these observations.

To illustrate the contribution of protein nanomechanics to biological function, I review current knowledge on the mechanobiology of selected muscle and cell adhesion proteins including titin, talin, and bacterial pilins.

OBJECTIVES To evaluate by systematic review current measures employed for screening for PAH.

Thus, in order to search for potential cold-tolerance biomarkers in fish at a post-transcriptional level, the aim of this work is to systematic review current literature on miRNAs related to low temperature in teleost fish and answer the question: are there any miRNAs related to key mechanisms of cold-tolerance in fish? Through a systematic search in 3 different databases, a total of 418 studies were initially identified.

In this statement, we first review current evidence on allergic reactions to vaccines and the potential risk factors that have been identified.

We first review current knowledge on PAOs, with a focus on bacteria, in terms of their phylogenetic identities, metabolic pathways and detection methods.

Objectives Review current evidence, therapeutic context, and possible mechanisms of action of different types of psychedelics in the treatment of PTSD.

Objective Review current evidence and knowledge concerning diagnosis, risk factors, disease evolution and treatment options of CPFE.

We summarize and critically review current knowledge on the molecular aspects of cell-death regulation during animal coronaviruses infection and the viral–host interactions to this process.

In this study, we review current knowledge of cross-talk among the endosperm, embryo, and seed coat during seed development, and highlight recent advances in this field.

Here, we review current literature on the role of climate change in the emergence of fungal diseases.

This commentary aims to review current literature on the cancellation of elective surgeries in response to the COVID-19 pandemic, summarize recommendations from several perioperative guidelines, and discuss key considerations for the resumption of elective surgeries in the post-pandemic world.

Herein we review current evidence on bimekizumab and sonelokimab.

OBJECTIVE This works aims to review current evidence regarding the pathological mechanisms leading from dysbiosis to schizophrenia and in particular the deficit syndrome in schizophrenia.

Here, we review current research on the microbiota and cancer development, and describe knowledge gaps in the study of radiotherapy and the microbiota.

Next, we review current research on semi-supervised, active, and transfer learning, and on differentiable computing methods such as deep learning.

To review current understanding of the prevalence, clinical features, outcome measures and recent therapeutic trials in axial psoriatic arthritis (axPsA).

Here we review current understanding of how SCFAs impact on human and animal physiology and discuss the potential applications of SCFAs in the prevention and treatment of human diseases.

Here, we briefly review current approaches and data and map an innovative patient-specific strategy to forecast drug resistance targets that centers on parallel (or redundant) proliferation pathways in specialized cells.

Here, we review current approaches to defining and monitoring gut microbiome health, and outline directions for developing targeted ecological therapeutics.

We review current progress in SMA therapeutics, clinical trials, shortcomings of current treatments, and implications for the treatment of other neurogenetic diseases.

Here we review current progress in unravelling heterogeneity in hPSC-cardiac cultures and in the identification of surface markers suitable for defining cardiac identity, subtype specificity, and maturation states.

Purpose The purpose of this paper is to review current practice in sharing and mining medical data revealing benefits, costs and ethical issues.

In this article, we review current practices in prehospital resuscitation and the studies that have informed these practices.

Here, we review current concepts regarding the specific subtypes of Cav channels expressed in the retina, their intrinsic properties and forms of modulation, and how their dysregulation could lead to retinal disease.

We will review current concepts regarding bioenergetic decline in heart failure (HF).

In this article, we outline the technical steps involved in radiomics and radiogenomics analyses with the use of artificial intelligence methods and review current applications in adult and pediatric neuro-oncology.

The authors in this paper review current applications of AI in clinical medicine and discuss the most likely future contributions that AI will provide to the healthcare industry.

Purpose The purpose of this study is to critically review current studies on job crafting to identify contextual factors related to employees’ job crafting and to integrate the findings to help organizations improve employees’ job crafting.

We review current studies in both the metastatic and neoadjuvant/adjuvant setting and present the available evidence of benefit and toxicity for these novel agents.

In the present study, we try to review current data about nutrition management of cancer patients within this pandemic, and nutritional prevention tools, in order to understand the outcomes of infected cancer patients and to avoid complications that can be associated with nutritional deficiencies.

Additionally, we review current data regarding biliary complications following radioembolization in patients with prior biliary intervention.

We review current strategies that target MDSC-mediated immunosuppression to enhance NK cell cytotoxic antitumor activity.

Given the central role for radiotherapy for many pediatric CNS tumors, we review current strategies that combine radiation with targeted therapies or immunotherapies.

This perspective article will review current recommendations and evidence-based interventions to evaluate missed opportunities for HIV prevention in US perinatal care settings.

The objective of this work is to review current recommendations and legislative documents on the use of out-of-field shielding in X-ray imaging, including those from national authorities and from international and national organisations and professional bodies.

Purpose of review This article will review current guidelines regarding surgical protocols for elective and nonelective surgeries during the severe acute respiratory syndrome coronavirus 2 pandemic.

This article aims to review current guidelines and recommendations, and to provide user friendly management strategies for the general physician.

Here, we review current methods used to assess impacts of prenatal environmental exposures on mammalian ovary development and female reproductive function.

Purpose of review Current methods to assess genetic risk of familial hypercholesterolemia and coronary artery disease (CAD) focus on testing monogenic mutations in well known genes.

In this article, we describe a case of poisoning with verapamil mixed with ethanol and review current treatment options.

In the present article, we review current treatment options and future trends in stage IIIA-N2 NSCLC.

This paper serves as a base to review current advances in pelletization of microalgae with fungi for the co-cultivation process.

The purpose of the study is to disclose the content of the concepts of “A Man Playing”, “A Machine Playing”, “Posthumanism” and “Essentiocognitivism”; review current advances in artificial intelligence and neural networks.

We focus on three main sections: review recent clinical results for locomotor restoration in complete SCI; discuss the contemporary understanding of electrical neuromodulation and signal transduction pathways involved in spinal locomotor networks; review current challenges of motor system modulation and future directions towards integrative neurorestoration.

Although feasibility investigations can advance evidence-based practice in psychology and education, we review current challenges for researchers to consider when incorporating a feasibility protocol into their intervention research agenda.

We review current clinical knowledge on the diagnosis and management of PUK.

Here, we provide an overview of recent developments in the field of oligonucleotide therapeutics in oncology, review current clinical trials, and discuss associated challenges.

Here, we review current efforts to use animal models for the identification of molecules, cell types, and circuits relevant to OCD pathophysiology.

We review current efforts to detect and classify them, and finally begin building a vocabulary to effectively discuss negative objects.

We also review current state-of-the-art biology, histopathology, computation, and genomics in the setting of the stroma.

We aim to provide context and explanation of the models, review current state-of-the-art literature, and identify open questions and promising future directions.

Lastly, we review current preclinical studies and discuss the clinical implications for developing let-7-based replacement strategies as potential cancer therapeutics that can be delivered through different platforms to target CSCs and reduce/overcome treatment resistance when applied alone or in combination with current chemo/radiation or molecularly targeted therapies.

Thus, we review current preclinical and clinical evidence regarding the efficacy of CBD in terms of positive, negative and cognitive symptoms treatment, safety profile, and molecular targets.

We review current uses of Global Positioning System technology and digital biosensors in the NFL and discuss the future role of this technology in injury prevention.

1,24-31 These publications typically review current uses of otolaryngology in our specialty and a majority.

The purpose of this article is to review current standard practice, expert opinions and outcomes in the management of esophageal perforations and postoperative leaks.

We also review current standards of care for multiple myeloma and provide a three and five-year overall survival prediction matrix.

We review current information concerning the global health issue of COVID-19 including promising approved drugs, e.

We review current information available on the regulatory approach to Clinical Trials and Machine Learning.

In this chapter, we describe the ultrasound findings of normally aerated and injured lungs, review current available evidence for the most common lung pathologies, and suggest an intuitive framework and cognitive aid for a structured diagnostic approach to LUS.

Here, we review current available knowledge regarding NET and the related NETosis process in cancer patients, with an emphasis on pre-clinical and clinical data fostering the identification and validation of biomarkers of NET with a predictive/prognostic role in cancer patients treated with immunotherapy agents.

The authors will review current trends, and future applications of transdermal technologies, with specific focus on providing a comprehensive understanding of transdermal drug delivery systems and enhancement strategies.

Finally, we review current trends and suggest future research directions based on the existing challenges.

Review current management against international guidelines for SFBO and IFB.

We also review current management practices highlighting recent developments and future prospects for its control.

This study aimed to (1) assess maternal dietary patterns in India; (2) examine enablers and barriers in adopting recommended diets; (3) review current policy and program strategies to improve dietary intakes.

Purpose The purpose of this article is to review current policies and research in the field of speech-language pathology in regard to targeting gender-neutral pronouns in language therapy and propose further research on the topic.

Considering the introduction of a dimensional PD model with ICD-11, we review current findings related to various forms of childhood trauma, and PDs, operationalized in the form of personality functioning and maladaptive traits.

In this article we review current findings of the role of the innate immune system in contributing to cancer treatment pain at the distal endings of peripheral nerve, in the nerve trunk, in the dorsal root ganglion and in the spinal dorsal horn.

Herein, we review current therapies for glioblastoma, the role of CCR5 in other cancers, and the potential role for CCR5 inhibitors in the treatment of glioblastoma.

Purpose of review Current therapies for autoimmune disorders often employ broad suppression of the immune system.

We review current methodology and state of the art in the field of fluorescence imaging to study intestinal barrier transport of peptides, and provide a comprehensive overview of the imaging-compatible in vitro, ex vivo, and in vivo platforms that currently are being developed to accelerate this emerging field of research.

Here, we review current methodologies, explore persistent challenges, and discuss the outlook for isobaric tag‐based quantitative phosphoproteomic analysis.

To review current US, as well as international, guidelines for anticoagulant reversal agents in patients on VKAs or DOACs presenting with GI bleeding prior to endoscopy, guideline-based management of coagulation defects, timing of endoscopy, and recommendations for resumption of anticoagulant therapy following hemostasis.

Purpose of review To review current US literature and describe the extent, source, and impact of disparities that exist among Black, Indigenous, and people of color (BIPOC) in surgical route and outcomes for hysterectomy, myomectomy, and endometriosis surgery.