Introduction to Regulating Trophoblast

What is/are Regulating Trophoblast?

Regulating Trophoblast - Objective Vascular endothelial growth factor (VEGF) plays a critical role in regulating trophoblast cell invasion and proliferation, involved in a variety of pregnancy complications, such as spontaneous abortion and pre-eclampsia. ^[1] However, the role of INO80 in regulating trophoblast cells and recurrent miscarriage (RM) remains elusive. ^[2] However, the roles of galectin-14 in regulating trophoblasts and in the pathogenesis of pregnancy complication have never been investigated. ^[3] Finally, both endogenous expression patterns and BAP1 overexpression experiments in human trophoblast stem cells suggest that the molecular function of BAP1 in regulating trophoblast differentiation and EMT progression is conserved in mice and humans. ^[4] Taken together, these findings indicate the important role of M2 macrophages in regulating trophoblasts EMT, migration and invasion, contributing to a new insight in concerning the crosstalk between macrophages and trophoblasts in the establishment and maintenance of normal pregnancy. ^[5] Significance Several techniques have identified ELF3 as particularly important in regulating trophoblast-specific HLA-C expression. ^[6] Endometrial extracellular vesicles are essential in regulating trophoblasts’ function. ^[7] Macrophages are the second-largest leukocytes at the maternal-fetal interface, which has been demonstrated to play essential roles in remodeling spiral arteries, maintaining maternal-fetal immune tolerance, and regulating trophoblast’s biological behaviors. ^[8] Taken together, our results suggest that SEC5 might be involved in regulating trophoblast cell migration and invasion through the integrin/Ca2+ signal pathway to induce cytoskeletal rearrangement. ^[9] Collectively, these results indicated that NUR77 may play a key role in regulating trophoblast invasion at early pregnancy. ^[10] This study aims to explore the functional role and the mechanisms of cryptochrome 2 (CRY2), a fundamental component of the circadian clock, in regulating trophoblast migration and invasion. ^[11] Galectins contribute to placentation by regulating trophoblast development, migration, and invasion during early pregnancy. ^[12] Studies by our group have previously identified that NOTCH1 plays a positive role in regulating trophoblast functions. ^[13] CONCLUSION ROR1 might be involved in the development of PE through regulating trophoblast viability, migration, and invasion by PI3K/AKT/mTOR signaling pathway. ^[14] This study aimed to explore the role of the H19/let-7/ITGB3 axis in regulating trophoblastic spheroid adhesion and in vitro invasion ability using the HTR-8/SVneo cell line and to investigate the expression levels of lncRNA H19 and ITGB3 in human products of conception. ^[15] The molecular mechanisms regulating trophoblast mitochondrial oxidative phosphorylation are largely unknown. ^[16] Human decidual stromal cells play a key role in regulating trophoblast invasion. ^[17] In this study, we aimed to investigate the potential role and underlying mechanism of miR-454 in regulating trophoblast cell proliferation and invasion in vitro. ^[18]

regulating trophoblast cell

Objective Vascular endothelial growth factor (VEGF) plays a critical role in regulating trophoblast cell invasion and proliferation, involved in a variety of pregnancy complications, such as spontaneous abortion and pre-eclampsia. ^[1] However, the role of INO80 in regulating trophoblast cells and recurrent miscarriage (RM) remains elusive. ^[2] Taken together, our results suggest that SEC5 might be involved in regulating trophoblast cell migration and invasion through the integrin/Ca2+ signal pathway to induce cytoskeletal rearrangement. ^[3] In this study, we aimed to investigate the potential role and underlying mechanism of miR-454 in regulating trophoblast cell proliferation and invasion in vitro. ^[4]

regulating trophoblast invasion

Collectively, these results indicated that NUR77 may play a key role in regulating trophoblast invasion at early pregnancy. ^[1] Human decidual stromal cells play a key role in regulating trophoblast invasion. ^[2]