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Refractory Recurrent sentence examples within neck squamous cell

neck squamous cell

Key Points Question Is nivolumab or pembrolizumab more cost-effective for treatment of US patients with platinum-refractory recurrent or metastatic head and neck squamous cell carcinoma? Findings In this cost-effectiveness analysis that included 487 patients, when the willingness-to-pay threshold was $100 000 per quality-adjusted life-year, for patients weighing less than 72 kg, nivolumab (3 mg/kg administered biweekly) was considered cost-effective; otherwise, pembrolizumab was preferable.

Nivolumab vs Pembrolizumab for Treatment of US Patients With Platinum-Refractory Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

neck squamous cell

Anti-programmed cell death protein 1 (PD-1) agents have become the standard of care for platinum-refractory recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) and are currently being evaluated in various disease settings.

Immune biomarkers of response to immune-checkpoint inhibitors in head and neck squamous cell carcinoma

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Refractory Recurrent sentence examples within metastatic squamous cell

metastatic squamous cell

In the Phase‐III clinical trial, CheckMate 141, nivolumab significantly improved survival versus standard of care in patients with platinum‐refractory recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN).

Pooled analysis of nivolumab treatment in patients with recurrent/metastatic squamous cell carcinoma of the head and neck in the United States and Germany

metastatic squamous cell

ObjectivesIn the CheckMate 141 trial (NCT02105636), nivolumab demonstrated survival, health-related quality of life, and healthcare resource utilization benefits vs single-agent therapy of investigator’s choice (IC) (methotrexate, docetaxel or cetuximab) in patients with platinum-refractory recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN).

A Q-TWiST Analysis Comparing Nivolumab and Therapy of Investigator’s Choice in Patients with Recurrent/Metastatic Platinum-Refractory Squamous Cell Carcinoma of the Head and Neck

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Refractory Recurrent sentence examples within refractory recurrent clostridial

refractory recurrent clostridial

Background Fecal microbiota transplantation (FMT) is now approved for the treatment of refractory recurrent clostridial colitis, but a number of studies are ongoing in inflammatory bowel diseases, i.

Long-term impact of fecal transplantation in healthy volunteers

refractory recurrent clostridial

BackgroundFecal microbiota transplantation (FMT) has been recently approved by FDA for the treatment of refractory recurrent clostridial colitis (rCDI).

Long-term impact of fecal transplantation in healthy volunteers

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10.1186/s13048-021-00790-4

Conclusions In platinum-sensitive recurrent ovarian cancer, PLD plus carbo was more effective than PAC plus carbo, while in platinum-resistant or -refractory recurrent ovarian cancer, PLD exhibited similar survival to other monotherapies.

The impact of Pegylated liposomal doxorubicin in recurrent ovarian cancer: an updated meta-analysis of randomized clinical trials

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10.3390/microorganisms9040684

Here, we describe the outcome of the infusion of in vitro expanded CMV-reactive T-cells, taken from a healthy CMV-seropositive donor, in a liver-transplanted recipient with a refractory recurrent CMV.

Successful Use of Heterologous CMV-Reactive T Lymphocyte to Treat Severe Refractory Cytomegalovirus (CMV) Infection in a Liver Transplanted Patient: Correlation of the Host Antiviral Immune Reconstitution with CMV Viral Load and CMV miRNome

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10.2147/OTT.S309661

We report on a patient with chemotherapy-refractory recurrent VCCC, who was found to have high tumor programmed death-ligand 1 (PD-L1) combined positive score (CPS), and subsequently experienced a durable partial response (PR), after treatment with off-label fifth-line pembrolizumab.

PD-L1 Expressing Recurrent Clear Cell Carcinoma of the Vulva with Durable Partial Response to Pembrolizumab: A Case Report

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10.1002/ccd.29444

• VBT is a good clinical option for patients with refractory recurrent ISR in the DES era.

Intravascular brachytherapy is a good clinical option for refractory in‐stent restenosis

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10.4103/jpgm.JPGM_1165_20

We report a case of 72-year-old male, with chronic alcohol abuse, presenting with atypical features like refractory recurrent secondary generalized seizures and behavioral disturbances with increased irritability, initially mistreated as alcohol withdrawal.

Unusual presentation of an insulinoma in an elderly male patient

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10.1136/heartjnl-2021-319282

Current guidelines unfortunately reflect this inertia, as there is relative paucity of additional therapies for patients with refractory recurrent pericarditis Cardiovascular Imaging, Cleveland Clinic, Cleveland, Ohio, USA.

Anti-interleukin-1 for recurrent pericarditis; maybe a fix (but prior studies do not really mix)

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10.1016/j.tjog.2019.07.007

OBJECTIVE To evaluate the effectiveness of etanercept in the treatment of refractory recurrent spontaneous abortion with innate immune disorders.

A randomized controlled trial of etanercept in the treatment of refractory recurrent spontaneous abortion with innate immune disorders.

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10.1200/JCO.2019.37.15_SUPPL.6073

6073Background: Nivo, which inhibits the programmed death-1 (PD-1) receptor, improved survival for pts with platinum-refractory recurrent/metastatic HNSCC.

Safety and disease control achieved with the addition of nivolumab (Nivo) to chemoradiotherapy (CRT) for intermediate (IR) and high-risk (HR) local-regionally advanced head and neck squamous cell carcinoma (HNSCC): RTOG Foundation 3504.

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10.1038/s41571-019-0227-z

Anti-programmed cell death 1 (PD-1) therapies, currently approved for platinum-refractory recurrent and/or metastatic HNSCC, offer the prospect of long-term remissions with fewer toxicities than traditional cytotoxic chemotherapy for a minority of patients, and are expected to advance to earlier lines of therapy.

The changing therapeutic landscape of head and neck cancer

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10.1200/JCO.2019.37.15_SUPPL.E17502

e17502Background: To evaluate the efficacy and safety of apatinib in treating patients with platinum-resistant or platinum-refractory recurrent or metastatic nasopharyngeal carcinoma.

Apatinib in treating patients with platinum-resistant or platinum-refractory recurrent or metastatic nasopharyngeal carcinoma.

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10.1101/671644

Background Fecal microbiota transplantation (FMT) is now approved for the treatment of refractory recurrent clostridial colitis, but a number of studies are ongoing in inflammatory bowel diseases, i.

Long-term impact of fecal transplantation in healthy volunteers

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10.1016/j.juro.2018.10.004

In this study we assessed the effectiveness, safety and feasibility of prophylactic treatment with intravesical gentamicin in patients with refractory recurrent urinary tract infections caused by multidrug resistant microorganisms.

Intravesical Gentamicin Treatment for Recurrent Urinary Tract Infections Caused by Multidrug Resistant Bacteria

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10.4103/RCM.RCM_4_19

Background: Refractory recurrent ventricular tachycardia is a difficult therapeutic problem.

Clinical results of combined amiodarone and mexiletine therapy in refractory ventricular tachycardias

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10.1016/j.vgie.2019.04.010

Some subgroups of patients show refractory recurrent bleeding despite standard endoscopic therapy.

Alternative approach to hemostatic particle spraying for treatment of GI bleeding by the use of cross-platform devices

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10.3390/ijms20215399

Nearly 10 years after the approval of cetuximab, anti-PD1/PD-L1 checkpoint inhibitors are the first drugs that have shown any survival benefit for the treatment on platinum-refractory recurrent/metastatic (R/M) HNSCC.

Immunotherapies and Future Combination Strategies for Head and Neck Squamous Cell Carcinoma

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10.3760/CMA.J.ISSN.1674-4756.2019.20.024

Objective To investigate the efficacy of thalidomide combined with DICE scheme in the treatment of refractory recurrent non-hodgkin lymphoma patients and the occurrence of toxic and side effects.

Clinical observation of thalidomide combined with DICE scheme in the treatment of refractory recurrent non-Hodgkin lymphoma

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10.1186/s12866-019-1689-y

BackgroundFecal microbiota transplantation (FMT) has been recently approved by FDA for the treatment of refractory recurrent clostridial colitis (rCDI).

Long-term impact of fecal transplantation in healthy volunteers

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10.1634/theoncologist.2019-0230

A patient with platinum-refractory recurrent oral cavity HNSCC underwent comprehensive genomic profiling (CGP) that identified an activating MET mutation (R1004).

MET Genomic Alterations in Head and Neck Squamous Cell Carcinoma (HNSCC): Rapid Response to Crizotinib in a Patient with HNSCC with a Novel MET R1004G Mutation.

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10.14740/JMC.V10I5.3282

We report a successful first birth case from a patient with refractory recurrent implantation failure (RIF) by using endometrial receptivity array (ERA) test in Japan.

The Reproductive Outcomes for the Infertile Patients With Recurrent Implantation Failures May Be Improved by Endometrial Receptivity Array Test

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10.1016/j.jcpa.2018.11.002

Long half-life SST analogues are now recommended for the systemic treatment of unresectable or radiation-refractory recurrent human meningiomas.

Somatostatin Receptor 2 Expression in Canine Meningioma.

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10.1093/annonc/mdz252.037

Background To evaluate the efficacy and safety of apatinib in treating patients with platinum-resistant or platinum-refractory recurrent or metastatic nasopharyngeal carcinoma.

Apatinib in treating patients with platinum-resistant or platinum-refractory recurrent or metastatic nasopharyngeal carcinoma

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10.1097/MD.0000000000017572

The prognosis of refractory recurrent RMS is extremely poor, and the 5-year survival rate is less than 20%.

CD56–chimeric antigen receptor T-cell therapy for refractory/recurrent rhabdomyosarcoma

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Refractory Recurrent
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What is/are Refractory Recurrent?

Refractory Recurrent - Conclusions In platinum-sensitive recurrent ovarian cancer, PLD plus carbo was more effective than PAC plus carbo, while in platinum-resistant or -refractory recurrent ovarian cancer, PLD exhibited similar survival to other monotherapies. [1] Here, we describe the outcome of the infusion of in vitro expanded CMV-reactive T-cells, taken from a healthy CMV-seropositive donor, in a liver-transplanted recipient with a refractory recurrent CMV. [2] We report on a patient with chemotherapy-refractory recurrent VCCC, who was found to have high tumor programmed death-ligand 1 (PD-L1) combined positive score (CPS), and subsequently experienced a durable partial response (PR), after treatment with off-label fifth-line pembrolizumab. [3] • VBT is a good clinical option for patients with refractory recurrent ISR in the DES era. [4] We report a case of 72-year-old male, with chronic alcohol abuse, presenting with atypical features like refractory recurrent secondary generalized seizures and behavioral disturbances with increased irritability, initially mistreated as alcohol withdrawal. [5] Current guidelines unfortunately reflect this inertia, as there is relative paucity of additional therapies for patients with refractory recurrent pericarditis Cardiovascular Imaging, Cleveland Clinic, Cleveland, Ohio, USA. [6] OBJECTIVE To evaluate the effectiveness of etanercept in the treatment of refractory recurrent spontaneous abortion with innate immune disorders. [7] 6073Background: Nivo, which inhibits the programmed death-1 (PD-1) receptor, improved survival for pts with platinum-refractory recurrent/metastatic HNSCC. [8] Anti-programmed cell death 1 (PD-1) therapies, currently approved for platinum-refractory recurrent and/or metastatic HNSCC, offer the prospect of long-term remissions with fewer toxicities than traditional cytotoxic chemotherapy for a minority of patients, and are expected to advance to earlier lines of therapy. [9] e17502Background: To evaluate the efficacy and safety of apatinib in treating patients with platinum-resistant or platinum-refractory recurrent or metastatic nasopharyngeal carcinoma. [10] Background Fecal microbiota transplantation (FMT) is now approved for the treatment of refractory recurrent clostridial colitis, but a number of studies are ongoing in inflammatory bowel diseases, i. [11] In this study we assessed the effectiveness, safety and feasibility of prophylactic treatment with intravesical gentamicin in patients with refractory recurrent urinary tract infections caused by multidrug resistant microorganisms. [12] Background: Refractory recurrent ventricular tachycardia is a difficult therapeutic problem. [13] Some subgroups of patients show refractory recurrent bleeding despite standard endoscopic therapy. [14] Nearly 10 years after the approval of cetuximab, anti-PD1/PD-L1 checkpoint inhibitors are the first drugs that have shown any survival benefit for the treatment on platinum-refractory recurrent/metastatic (R/M) HNSCC. [15] Objective To investigate the efficacy of thalidomide combined with DICE scheme in the treatment of refractory recurrent non-hodgkin lymphoma patients and the occurrence of toxic and side effects. [16] BackgroundFecal microbiota transplantation (FMT) has been recently approved by FDA for the treatment of refractory recurrent clostridial colitis (rCDI). [17] A patient with platinum-refractory recurrent oral cavity HNSCC underwent comprehensive genomic profiling (CGP) that identified an activating MET mutation (R1004). [18] We report a successful first birth case from a patient with refractory recurrent implantation failure (RIF) by using endometrial receptivity array (ERA) test in Japan. [19] Long half-life SST analogues are now recommended for the systemic treatment of unresectable or radiation-refractory recurrent human meningiomas. [20] Background To evaluate the efficacy and safety of apatinib in treating patients with platinum-resistant or platinum-refractory recurrent or metastatic nasopharyngeal carcinoma. [21] The prognosis of refractory recurrent RMS is extremely poor, and the 5-year survival rate is less than 20%. [22]

neck squamous cell

Key Points Question Is nivolumab or pembrolizumab more cost-effective for treatment of US patients with platinum-refractory recurrent or metastatic head and neck squamous cell carcinoma? Findings In this cost-effectiveness analysis that included 487 patients, when the willingness-to-pay threshold was $100 000 per quality-adjusted life-year, for patients weighing less than 72 kg, nivolumab (3 mg/kg administered biweekly) was considered cost-effective; otherwise, pembrolizumab was preferable. [1] Anti-programmed cell death protein 1 (PD-1) agents have become the standard of care for platinum-refractory recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) and are currently being evaluated in various disease settings. [2] 68Background: Nivolumab improved overall survival (OS) in the treatment of platinum-refractory recurrent and metastatic head and neck squamous cell carcinoma (R/M HNSCC) in a phase III clinical tri. [3]

metastatic squamous cell

In the Phase‐III clinical trial, CheckMate 141, nivolumab significantly improved survival versus standard of care in patients with platinum‐refractory recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN). [1] ObjectivesIn the CheckMate 141 trial (NCT02105636), nivolumab demonstrated survival, health-related quality of life, and healthcare resource utilization benefits vs single-agent therapy of investigator’s choice (IC) (methotrexate, docetaxel or cetuximab) in patients with platinum-refractory recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN). [2] Background Nivolumab, approved in Japan for platinum-refractory recurrent/metastatic squamous cell carcinoma of the head and neck (RM-SCCHN) in 2017, is of uncertain cost-effectiveness. [3]

refractory recurrent clostridial

Background Fecal microbiota transplantation (FMT) is now approved for the treatment of refractory recurrent clostridial colitis, but a number of studies are ongoing in inflammatory bowel diseases, i. [1] BackgroundFecal microbiota transplantation (FMT) has been recently approved by FDA for the treatment of refractory recurrent clostridial colitis (rCDI). [2]