Introduction to Refractory Constipation

Methods A total of 169 patients with refractory constipation with a mean age of 67 years were studied.

Background Patients with chronic refractory constipation show colon dysmotility, including impaired coordination of descending colon-sigmoid colon-rectum-anal sphincter motor functions; this may involve slow colonic transit and colo-anal dyssynergia.

Among 169 patients with refractory constipation, 79 (46.

Surgical treatment of constipation is reserved for cases of refractory constipation, with delayed intestinal transit.

Chronic refractory constipation (CRC) is defined as children who are unable to pass stools in spite of being on maximum laxative therapy and require daily rectal stimulation in the form of enemas or suppositories to pass stools for >3 months.

In this prospective study, patients presenting refractory constipation highly suggestive of HD underwent hydrocolonic sonography with retrograde infusion of saline into the colon.

Mashininigan might be an alternative option to improve refractory constipation in patients with cardiac amyloidosis.

Specific heart rate variability (HRV) parameters were used to assess general orthostatic autonomic reactivity, and autonomic functioning during high resolution colonic manometry, in 14 patients with chronic refractory constipation considered for surgery.

INTRODUCTION Antegrade continence enemas have transformed treatment and improved the quality of life in children with neuropathic bowel, refractory constipation and fecal incontinence.

Most common presentation includes abdominal distention, refractory constipation, and bowel obstruction like many other colorectal conditions.

ConclusionsOur results agree with current studies which describe around a 30% response of SNS for refractory constipation.

Most of the patients had refractory constipation.

However, refractory constipation may persist despite the addition of a second agent.

003), refractory constipation (P<0.

Targeting treatments for the dysbiosis of constipation by probiotics, prebiotics, synbiotics, antibiotics, and FMT may be a new option, especially for refractory constipation to conventional therapies.

Percutaneous endoscopic cecostomy (PEC) is an uncommonly used rescue approach for refractory constipation and/or pseudoobstruction.

The technique is (with minor adjustments) also useful for other conditions such as gastric emptying disorders and refractory constipation.

Approximately 5 years after the incident, she began having issues of refractory constipation.

, systemic opioids causing refractory constipation, nausea, vomiting, or sedation).