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H2O2-induced oxidative stress increases the levels of reactive oxygen species and reduces membrane potential in hMSCs, leading to mitochondrial dysfunction and cell death.
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Whole-cell electrophysiological recording indicates that blue-light reduces membrane potential of lateral habenula neurons.
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Bituminous clays in produced water are heavily charged and interact with the charged surfaces of ceramic membranes in a way that reduces membrane performance.
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The findings indicate that (a) N-chlorination reduces membrane polarity and ion permeability, while C-chlorination has an opposite effect; (b) chlorination in acidic conditions must involve other reactions, such as direct ring chlorination, in addition to N-chlorination and Orton rearrangement; and (c) the ultimate chemical transformations (C-chlorination or amide bond scission) result in an irreversible increase in membrane polarity and loss of ion rejection.
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7-Ketocholesterol, which weakens ψd and reduces membrane-perpendicular dipole–dipole repulsion, causes a discrete second peak on the high-temperature side of the main transition, whereas 6-ketocholestanol, which strengthens ψd and increases membrane-perpendicular dipole–dipole repulsion, merely produces a shoulder.
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1 and reduces membrane expression.
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H2O2-induced oxidative stress increases the levels of reactive oxygen species and reduces membrane potential in hMSCs, leading to mitochondrial dysfunction and cell death.
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In the yeast Saccharomyces cerevisiae, a downward shift in temperature from an optimal reduces membrane fluidity, which triggers a lipid remodeling of the plasma membrane.
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Here, we reveal that the APAP metabolite NAPQI, but neither the parent compound nor the metabolite AM404, reduces membrane excitability in rat dorsal root ganglion (DRG) and spinal dorsal horn (SDH) neurons.
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Pharmacological inhibition of HDAC6 in primary human CF bronchial epithelial cells also reduces membrane cholesterol levels.
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Notably, a top drop-out hit was glutathione peroxidase 4 (GPX4), an essential antioxidant enzyme that reduces membrane phospholipid hydroperoxides to prevent a form of non-apoptotic cell death known as ferroptosis.
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Healthy RBCs were rigidified by treatment with lysolecithine (LPC), diamide or nystatine associated with hyperosmolar solutions (OSMO), which reduces membrane surface area, decreases membrane elasticity or promotes cell dehydration, respectively.
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Biofouling is a severe problem in membrane systems which hampers their broad applications because it requires regular chemical cleaning, reduces membrane life, and also decreases product quality.
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Whole-cell electrophysiological recording indicates that blue-light reduces membrane potential of lateral habenula neurons.
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