Introduction to Randomized Prospective

This open label, non-randomized prospective safety and feasibility study was investigator initiated.

A pilot open-label non-randomized prospective study with the inclusion of 6 patients with HCV-LP.

Multi-centered, randomized prospective study with larger sample size should be conducted.

Multi-centered, randomized prospective study with larger sample size should be conducted.

Thirty-nine patients with MS were assigned within a randomized prospective longitudinal pilot study to (1) a routine clinical rehabilitation program, (2) a routine clinical rehabilitation program + normoxic endurance training and (3) a routine clinical rehabilitation program + hypoxic endurance training for 14 days.

Future randomized prospective studies must confirm these indicative results.

Future randomized prospective studies are needed to fully assess the possible role for iOCT in ERM surgery and evaluate the potential impact of non-foveal ERM persistence/recurrence in comparison to conventional surgery.

STUDY DESIGN The RECOPANC trial was a multicenter randomized prospective trial of patients undergoing pancreatoduodenectomy.

Hodin and Pawlik, As pediatric surgeons with an interest in biliary diseases, we eagerly read the article by Gao and colleagues titled “A Multicenter Randomized Prospective Study of Early Cholecystectomy for Pediatric Patients with Biliary Colic”.

Moreover, well-designed randomized prospective trials for better evidence are required.

These results need to be validated in a well-designed randomized prospective trial.

Methods A blinded randomized prospective trial conducted at Orthopaedic department of a tertiary institute in India from Feb 2019 to June 2019.

Methods: One Hundred adults undergoing kidney transplantations were enrolled in a double-blinded randomized prospective clinical trial.

Large randomized prospective studies have shown prognostic benefit in patients with heart and/or renal insufficiency regarding cardiovascular and general endpoints - even in absence of type 2 diabetes mellitus.

Recently, several large randomized prospective trials have been published, and there are ongoing randomized trials for resectable BTC.

Larger Randomized prospective studies alone or in combination with steroids are needed to confirm our results.

These observations require further confirmation in larger randomized prospective clinical trials.

Methods This two-arm open-label randomized prospective study was conducted from April 1, 2019 to March 30, 2020 in a tertiary care hospital at Pakistan.

Study Design: In this open-label randomized prospective controlled study, 60 unexplained infertility patients enrolled for in vitro fertilization treatment were randomized by a computer-based number generator for acupuncture performance and no-treatment.

BACKGROUND: In the present randomized prospective study, 2 different surgical techniques of plantar fasciitis surgery were compared.

The effect of doxycycline in COPD is hereby assessed in the present randomized prospective study.

This is a hospital based non randomized prospective interventional study.

Methods: Total 351 patients were enrolled in this observation non randomized prospective cohort.

Five trials were uncontrolled prospective studies (215 patients, 14% of total), nine were retrospective studies (1266 patients, 82,6% of total), and one randomized prospective clinical trial (RCT) (50 patients, 3,32% of total).

All studies were retrospective, except for one randomized prospective study.

[4,5] Interestingly, ophthalmology provided the first randomized prospective clinical trial to try and determine the treatment for diabetic retinopathy.

On the other hand, it is one of the first randomized prospective pilot trial that compared the efficiency of performing two consecutive ovarian stimulation in different menstrual cycles with the DuoStim strategy.

A controlled randomized prospective study was conducted on the basis of a private rehabilitation center «Ezramed-Clinic» in Omsk in the period from February 2019 to December 2019.

This was a placebo-controlled randomized prospective study.

Large-scale randomized prospective studies are needed to further support the application of minimally invasive surgery.

Further, large scale randomized prospective studies are warranted to investigate the role of thiamine supplementation in critically ill patients.

Materials and Methods: A randomized prospective study has been conducted from November 2018 to November 2020 on 30 patients with CRC were randomized to the total laparoscopic colectomy (TLC) group (15 patients) or laparoscopic-planned conversion colectomy LPCC group (15 patients).

The purpose of this randomized prospective study was to evaluate the 7-year outcome of patients with immediate and early loaded single-tooth restorations supported by implants with plasma-sprayed, partially HA-coated surfaces.

One reason for the slow adoption of MIS has been the lack of randomized prospective trials comparing the conventional sternotomy approach with MIS.

CONCLUSION Randomized prospective trials are needed to standardize treatment in MZL.

Methods A randomized prospective clinical trial has been set up to answer the research hypothesis.

In any case, no randomized Prospective clinical examinations have explored this specific inquiry.

A non-randomized prospective controlled clinical trial was conducted.

Randomized prospective controlled trials that investigated the effects on cardiovascular events in CKD patients that were published in English from 2010 to 2020 were included.

PATIENTS AND METHODS This is a randomized prospective comparative study of 150 patients diagnosed with H.

Patient and methods: this a randomized Prospective comparative study has done Al-Azhar university hospitals (Al-Hussein and Sayed Galal), where fifty-one patients have been diagnosed to have plantar fasciitis were included and allocated into one of three groups (17 patients in each group) to receive an ultrasound-guided injection of corticosteroid (control group), platelet-rich plasma (PRP) or Ozone O2-O3.

Design This non-randomized prospective cohort trial evaluated patients undergoing elective cesarean section during the reopening phase of the Covid-19 pandemic in New York State at two large volume Labor and Delivery Units.

Patients and methods: This randomized prospective cohort study was conducted on 300 pregnant women from the second trimester with IDA who were enrolled and randomly separated on 2 groups; ferrous sulphate group: 150 pregnant women received 150 mg of dried ferrous sulphate capsules.

Twenty patients aged 60 or older undergoing on-pump coronary artery bypass graft (CABG) surgery or combined CABG/valve surgeries were enrolled in this non-randomized prospective observational feasibility trial, wherein we developed MMGA specifically for cardiac surgeries.

Material and Methods: The present study is a non-randomized prospective observational study, conducted in the department of neurosurgery, Bangur Institute of Neurosciences (B.

Settings and design In this randomized prospective interventional study, we recruited 24 patients with COPD from the Chest Department, Alexandria Main University Hospital, having homogenous or heterogonous emphysema and complaining of severe symptoms despite optimized medical treatment, and they were divided into group I, including 12 patients subjected to BLVRS using silver nitrate, and group II, including 12 patients subjected to BLVRS using histoacryl.

This is a hospital based non randomized prospective interventional study.

Methods A randomized prospective pilot trial was performed including patients with brain metastasis or bone metastasis of solid tumors.

A randomized prospective pilot study was performed in 15 patients (9 men, 6 women) with 15 teeth vital pulpectomy.

Methods: In a randomized prospective design, hypothyroid patients taking levothyroxine were randomized to receive instructions to take levothyroxine at one of the following 3 times during Ramadan: (group 1) at dusk 30-min before Iftar meal, (group 2) 3 or more hours after Iftar meal, or (group 3) at dawn 30-min before Suhur meal.

Thirty-six percent of the articles had a nonrandomized prospective design, followed by cross-sectional studies (26%) and randomized prospective studies (18%).

Methods: A total of 100 ASA I-II adult patients between 18 and 60 years of age with no psychiatric, cardiovascular, or metabolic disorders, who were operated under general anesthesia for various reasons at Firat University Hospital between June and November 2013 were included in this randomized prospective case-control study.

SUBJECTS/ METHODS In this non-randomized prospective case-controlled study, 28 subjects recruited; 14 with ET for at least 5 years and 14 without ET.

Clinical efficacy of intradiscally injected celecoxib (CXB)-loaded polyesteramide microspheres (PEAMs) was studied in a randomized prospective double-blinded placebo controlled veterinary study.

Methods: Randomized prospective double-blind placebo-controlled trial with 28 day and 60 day endpoints.

Design: Single center two-armed cluster randomized prospective crossover pilot study.

To evaluate HFNC for acute childhood asthma, we designed a randomized prospective crossover trial.

PURPOSE/OBJECTIVE(S) In the absence of randomized prospective data, the role of postoperative radiotherapy (PORT) for localized Merkel cell carcinoma (MCC) is controversial with varying practice patterns.

Objective High grade and non-endometrioid endometrial cancers carry a poor prognosis, and the lack of randomized prospective data has led to a wide range of practice regarding adjuvant therapy.

In this study, we hypothesized that the Nintendo Ring Fit Adventure (RFA) exergame would be effective for patients with chronic low back pain, and we conducted a randomized prospective longitudinal study.

Thirty-nine patients with MS were assigned within a randomized prospective longitudinal pilot study to (1) a routine clinical rehabilitation program, (2) a routine clinical rehabilitation program + normoxic endurance training and (3) a routine clinical rehabilitation program + hypoxic endurance training for 14 days.

DESIGN A randomized prospective multicenter study with a blinded evaluator.

The PROTECT trial is a nonrandomized prospective multicenter phase-II-trial comparing clinical outcomes after IMPT or IMRT/VMAT in LACC.

We enrolled 30 patients with solid tumor cancers into a non-randomized prospective intervention trial (NCT02627079): 15 had completed treatment in the past year and 15 under active treatment.

Methods and Results:This non-randomized prospective intervention study involved 136 patients (non-OCR group, n=66; OCR group, n=70), 55 of whom were aged ≥75 years (non-OCR group, n=29; OCR group, n=26).