Introduction to Randomized Interventional

Further work, including large observational or randomized interventional studies, is needed to develop a better understanding of the effect of BP lowering on ICP in acute ICH, which will assist the development of more effective management strategies.

Background: This randomized interventional study evaluated the impact of a 1-day experiential communication skills training on neonatologists' performance in doctor-parents-communication.

Patients and methods Retrospective comparative nonrandomized interventional case series including consecutive patients who underwent PPV with or without encircling band and SO tamponade for RRD associated with buphthalmos.

A total of 843 studies were captured by the initial search and 96 were included in the final review (25 randomized controlled trials, 37 observational studies, and 34 non-randomized interventional studies).

DESIGN Nonrandomized interventional comparison study.

We will exclude all randomized and non-randomized interventional studies.

SETTINGS AND DESIGN: A prospective, double-blinded, randomized interventional study.

Methods: A therapeutic, prospective, randomized interventional study was carried out.

It was conducted an open-label prospective nonrandomized interventional study in which we have enrolled a total number of 111 patients diagnosed with prostate cancer that underwent radical prostatectomy.

METHODS In a prospective, multicenter, stepped-wedge cluster randomized interventional study in nine academic and non-academic hospitals in the Netherlands, we studied the impact of adding standardized postoperative anesthesia visits on day one and three to routine use of MEWS in 5473 patients undergoing elective non-cardiac surgery.

To understand whether early ART affects HIV-1 persistence in vivo, we performed single-cell ECCITE-seq and profiled 89,279 CD4+ T cells in paired samples during viremia and after immediate versus delayed ART in six people in the randomized interventional Sabes study.

Methods: The hospital-based prospective randomized interventional study was done where a total of 60 patients of Cw were divided into two groups of 30 patients each: Group A received 0.

This prospective, nonrandomized interventional cohort study was conducted in infants aged 0-12 months with congenital CLP.

Moreover, despite the fact that the analysis of the Scleroderma Lung Studies I and II was not included in the MA as a non-randomized interventional study, albeit being published in the year 2017 [8], both Ma et al.

Methods: This randomized interventional study was conducted with parallel groups on 90 pregnant women referring to Urmia Health centers in 2018-2019.

Research design and Methods: This prospective open-label randomized interventional study was conducted among newly diagnosed prediabetes in selected districts of Kerala and Tamil Nadu in South India.

PURPOSE This is a retrospective, single-center, non randomized interventional real life study, investigating the correlation between variability of central retinal thickness (CRT) and functional outcomes during 2 years of anti-VEGF therapy in patients treated for neovascular age related macular degeneration (nAMD).

Materials and Methods We conducted a prospective randomized interventional study of 18 months’ duration, with 30 patients.

In order to assess the short-term efficacy of basic life support simulation, in addition to the institutional training, a prospective single-blinded randomized interventional study was performed.

A non-randomized interventional trial without control study was conducted in the Rural field practice area of Department of Community Medicine, S.

0 tool for randomized controlled trials, Risk of Bias In Non-Randomized Studies - of Interventions (ROBINS-I) tool for non-randomized interventional studies, and Joanna Briggs Institute Critical Appraisal tools (JBI) for cohort studies.

However, future randomized interventional trials are required to confirm these findings.

Methods: Prospective randomized interventional study.

Methods This single-blind, placebo-controlled randomized interventional study was conducted in the Internal Medicine Department of a tertiary care hospital in Pakistan from March 2018 to July 2020.

The included studies consisted of case reports/series and non-randomized interventional studies, with knee osteoarthritis and adhesive capsulitis of the shoulder as the most frequent conditions.

Thus, randomized interventional studies are necessary to advance causal inferences and, if causality is confirmed, to provide hope that an etiological treatment for a distinct subgroup of individuals at an increased risk for suicide could emerge.

Design This was a prospective nonrandomized interventional clinical study.

Patients and methods A prospective randomized interventional study was performed at Al-Zahraa Hospital, during the period from April 2017 to December 2018.

Patients and methods A prospective comparative nonrandomized interventional study was conducted on patients attending the Outpatient Clinic of the Ophthalmology Department in Al Azhar University Hospital (Damietta branch) during the period from April 2018 to August 2019.

MATERIAL AND METHODS A prospective randomized interventional open-label endpoint-controlled study was conducted in an academic tertiary care hospital.

We performed a prospective non-randomized interventional study to learn about the effects of a subthreshold laser treatment (Topcon Endpoint Management™, Topcon Healthcare Inc.

Method: A randomized interventional study was done at the Cardiology Clinic of LAUTECH Teaching Hospital, Ogbomoso, Nigeria.

A nonrandomized interventional study was conducted from January 2017 to February 2020 in Shanghai, China.

METHODS This is a retrospective, consecutive, comparative, non-randomized interventional study.

A prospective controlled cohort non-randomized interventional study was conducted: within the years 2014 to 2020, there were examined 546 women with genital malignancies, divided into 2 groups: group I – 155 cancer patients with former thrombosis, group II – 391 women with female genital cancer without former thrombotic complications.

The prospective open non-randomized interventional study (Siena Eye-Cross Study 2) included 156 eyes of 112 patients with early progressive KC undergoing the Epi-Off 9 mW/5.

Methods: This study is a single-blinded randomized interventional or clinical trial study conducted on 90 elderly people under the coverage of two large health centers during 2019 - 2020 in Shiraz, Iran.

However, in our short term randomized interventional study Posterior Cruciate substitution Total Knee Arthroplasty had a marginally better outcome than the posterior Cruciate retaining in terms of range of motion but it needs a long-term analysis.

Methods This is a retrospective analysis of an IRB approved prospective, non-randomized interventional experience at a single institution with two DP systems.

Settings and design This was a prospective randomized interventional study.

A prospective, non-randomized interventional trial was conducted.

Study Design: A prospective non-randomized interventional case series.

MATERIAL AND METHODS In a prospective randomized interventional study, 10 healthy Holstein-Friesian calves (age range 3-6 month) were sedated with either xylazine (0.

To address this issue, a randomized interventional study was carried out in a pediatric tertiary hospital to qualify and quantify the potential beneficial effect of pyridoxine in attenuating the neuropsychiatric side effects of levetiracetam in children.

Patients and methods: It is a prospective non-randomized interventional study.

A total of 18 studies were included in the review: 9 RCTs and 9 non-randomized interventional/observational studies.

Conclusion We intend to use the data obtained from this pilot study to develop a larger, randomized interventional trial evaluating the effects of an intense multimodal rehabilitation program in improving long-term patient outcomes (including patient and graft survival) in cardiothoracic transplant recipients and as well as hospital length of stay and rate of early re-admission.

STUDY DESIGN Single-blind randomized interventional clinical trial.

METHODS A non-randomized interventional study was performed among eyes with super-refractory DME refractory to anti-VEGF therapy.

Introduction: This is a prospective nonrandomized interventional clinical trial conducted to measure and verify the intended versus the achieved LASIK flap side-cut angle in two groups of patients, Femtosecond laser-assisted in-situ keratomileusis (FS-LASIK) using Wavelight FS200 (Alcon Laboratories Inc.

The only pilot, randomized interventional study based on 50 patients undergoing surgery did not find a difference in outcomes on the basis of the use of SstO2 monitoring.

MethodsA prospective randomized interventional clinical study included patients with DME attending Al Hadi Clinic, Kuwait, during the period from May 2017 to December 2018.

A prospective randomized interventional study was conducted on airway stenting.

METHODS As a prospective randomized interventional trial, 36 eyes from 36 patients after OAG surgery were collected and divided randomly into conbercept and 5-FU groups.

METHODS In this Institutional Review Board approved nonrandomized interventional trial first year medical students performed our previously described dowel and straw ultrasound guidance targeting tasks as a pretest.

Methods: This secondary study used baseline data of a randomized interventional trial implemented in Jiangsu, China.

This non-randomized interventional pragmatic clinical trial aimed to explore whether consolidative allogeneic hematopoietic stem cell transplantation (allo-HSCT) could improve the long-term prognosis of the minimal residual disease-negative complete remission (MRD- CR) patients after CAR-T therapy.

This open-label non-randomized interventional study involved obese (BMI ≥ 25–35 kg/m2) and non-obese (BMI 18.

DESIGN Single-center prospective randomized interventional case-controlled trial.

Methods: This prospective non-randomized interventional study was conducted on adult mechanically ventilated patients admitted to the intensive care unit (ICU) within 24 hours from the diagnosis of septic shock and receiving Nor-epinephrine.

MethodsA prospective open label, parallel, non-randomized interventional trial was conducted in patients with Hepatitis-C on maintenance hemodialysis.

Methodology:  This study was done as a part of the non-randomized interventional study to assess the Effectiveness of Intervention by Accredited Social Health Activists (ASHAs) in the control of hypertension and diabetes in a rural population of Kolar District, Karnataka.

Although randomized interventional studies are difficult to perform in this setting, a variety of data suggest that factors such as maternal nutrition and stress result in adaptive changes in the fetus, affect fetal growth and development, and influence the risk of disease in later life.

This non‐randomized interventional pragmatic clinical trial had a particular aim.

Materials and Methods: A prospective randomized interventional study was conducted with patients with DUB.

The study was designed as a non‐randomized interventional study.

This cluster randomized interventional trial included 187 second‐year medical students.

METHODOLOGY AND RESULTS The present study was a nonrandomized interventional study conducted among visually impaired school children.

Further randomized interventional trials are needed to investigate which drug combinations are most appropriate according to patient CV risk stratification, in order to improve their CV outcomes.

Methods: This prospective non-randomized interventional study included injected and fellow eyes of 12 patients with DME and of 16 patients with RVO treated with intravitreal Ozurdex®.

Methods: We systematically searched the literature to identify randomized controlled trials, non-randomized interventional studies, or observational studies of multidisciplinary CKD clinics defined by an outpatient setting where two or more allied health members (with or without a nephrologist) provided longitudinal care to 50 or more adult or pediatric patients with CKD.

Methods: A prospective randomized interventional study was carried out among 120 patients of moderate to severe acne vulgaris.

5) with varying cognitive abilities (normal = 28, mild impairment = 17, moderate impairment = 12, severe impairment = 3, unknown cognitive score = 6), and/or physical impairments, entered a multi-site non-randomized interventional study in Toronto, Canada.

METHODS In a prospective, randomized interventional pilot trial, 30 patients received either hydrocortisone (100 mg over 10 min) or placebo (saline control) before surgery.