Introduction to Randomised Trial
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Randomised Trial sentence examples within stepped wedge cluster
Randomised Trial sentence examples within double blind placebo
METHODS
In this double-blind, placebo-controlled randomised trial, children were randomly assigned (1:1) to receive a 5-day course of azithromycin (oral suspension 10 mg/kg on day 1, followed by 5mg/kg per day on days 2-5) or identically appearing and tasting placebo at discharge from four hospitals in western Kenya.
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Randomised Trial sentence examples within multicentre double blind
Methods
This investigator-initiated, multicentre, double-blind, randomised trial was done at seven hospitals in the USA.
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METHODS
DAPA-CKD was a multicentre, double-blind, placebo-controlled, randomised trial done at 386 sites in 21 countries.
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Randomised Trial sentence examples within open label multicentre
Pembrolizumab was evaluated in a phase III, open-label, multicentre, randomised trial versus standard of care (SOC: FOLFOX6/FOLFIRI alone or in combination with bevacizumab/cetuximab) as first-line treatment of locally confirmed mismatch repair-deficient or microsatellite instability-high stage IV CRC.
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We did a phase 3, open-label, multicentre, randomised trial at 35 hospitals in France.
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Randomised Trial sentence examples within open label phase
Randomised Trial sentence examples within interrupted time series
SELECTION CRITERIA: For the primary objective, we included individual and cluster-randomised trials; cross-over and stepped-wedge study designs; controlled before-after studies, provided they have at least two intervention sites and two control sites; and interrupted time series studies.
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Selection criteria Randomised trials, non‐randomised trials, interrupted time series (ITS) studies, and controlled before‐after (CBA) studies conducted in any population or setting that assessed one or more of the following interventions that governments use to regulate private health insurance: legislation and licensing, monitoring, auditing, and intelligence.
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Randomised Trial sentence examples within multicentre open label
Design: Prospective, multicentre, open-label, multi-arm, adaptive Platform Randomised Trial of Treatments in the Community for Epidemic and Pandemic Illnesses (PRINCIPLE).
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Alam N, Oskam E, Stassen PM, et al; PHANTASi Trial Investigators and the ORCA (Onderzoeks Consortium Acute Geneeskunde) Research Consortium the Netherlands: Prehospital antibiotics in the ambulance for sepsis: A multicentre, open label, randomised trial.
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Randomised Trial sentence examples within coronary artery disease
In this issue of Heart, Tijssen and colleagues evaluated weight change from baseline to 12month followup in the subgroup of overweight patients (BMI ≥27 kg/m) with coronary artery disease in the Randomised Evaluation of Secondary Prevention by Outpatient Nurse SpEcialists-2 (RESPONSE-2) multicentre randomised trial.
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METHODS AND RESULTS
From inception through November 2020, MEDLINE, EMBASE, Google Scholar, and other databases were searched for randomised trials comparing revascularisation against medical therapy alone in clinically stable coronary artery disease patients.
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Randomised Trial sentence examples within also searched clinical
We also searched clinical trials databases and the reference lists of retrieved articles for randomised controlled trials (RCTs) and quasi-randomised trials.
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We also searched clinical trials databases and the reference lists of retrieved articles for randomised controlled trials (RCTs) and quasi-randomised trials.
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Randomised Trial sentence examples within two arm parallel
A two-arm, parallel-group, randomised trial with pragmatic features and three post-baseline evaluations (8 weeks, 12 weeks, 24 months) was conducted with 206 gamblers (106 unguided; 101 guided).
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Methods The PRESIDE study is designed as a two-arm, parallel-group randomised trial with a waiting list control.
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Randomised Trial sentence examples within arm parallel group
Methods This ten-centre, three-arm, parallel-group, single-blind, pragmatic, individually randomised trial screened ED attenders aged between 14 and 17 years for alcohol consumption.
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An interim analysis of a three-arm, parallel group randomised trial with participants (n = 655) randomly allocated to; 1) real-time video counselling; 2) telephone counselling; or 3) written materials only (minimal intervention control).
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Randomised Trial sentence examples within hospital cardiac arrest
AIMS
We recently reported early outcomes in patients enrolled in a randomised trial of adrenaline in out-of-hospital cardiac arrest: the PARAMEDIC2 (Prehospital Assessment of the Role of Adrenaline: Measuring the Effectiveness of Drug Administration in Cardiac Arrest) trial.
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Questions explored in-hospital cardiac arrest frequency, grade and specialty of those attending, proportion of patients receiving advanced airway management, airway strategies immediately available, and views on a randomised trial of airway management strategies during in-hospital cardiac arrest.
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Randomised Trial sentence examples within # # #
### Topic: treatment
#### Rating: game changer
In March 2020, the WHO recommended randomised trials into potential treatments for COVID-19.
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Randomised Trial sentence examples within Cluster Randomised Trial
Randomised Trial sentence examples within Prospective Randomised Trial
Randomised Trial sentence examples within Controlled Randomised Trial
METHODS
In this double-blind, placebo-controlled randomised trial, children were randomly assigned (1:1) to receive a 5-day course of azithromycin (oral suspension 10 mg/kg on day 1, followed by 5mg/kg per day on days 2-5) or identically appearing and tasting placebo at discharge from four hospitals in western Kenya.
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Randomised Trial sentence examples within Multicentre Randomised Trial
BACKGROUND
A multicentre randomised trial demonstrated improved outcomes for intensive care unit (ICU) patients using early, goal-directed mobility implemented by nurses.
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Methods ACST-2 is an international multicentre randomised trial of CAS versus CEA among asymptomatic patients with severe stenosis thought to require intervention, interpreted with all other relevant trials.
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Randomised Trial sentence examples within Pragmatic Randomised Trial
Interpretation Using data from a pragmatic randomised trial, one-off Cytosponge-TFF3 screen is cost-effective relative to usual care for patients with gastro-esophageal reflux disease, despite relatively low uptake and an older population in this trial setting than previously modelled.
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Randomised Trial sentence examples within Group Randomised Trial
There were five descriptive, non-comparative case series; two nonblinded parallel group randomised control trials; one blinded, placebo-controlled parallel group randomised trial and one prospective, randomised crossover trial
Strength of evidence
Weak
Outcomes reported
The current recommended oral dose of meloxicam in rabbits of 0.
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METHODS
COMIC is a multicentred, parallel-group randomised trial performed in Canada, Saudi Arabia, and Poland.
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Randomised Trial sentence examples within Large Randomised Trial
Randomised Trial sentence examples within Designed Randomised Trial
Randomised Trial sentence examples within Quality Randomised Trial
Most add-ons are not supported by good quality randomised trial evidence of efficacy, with some proven to be ineffective.
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High-quality randomised trials have provided evidence that nutritional therapy can reduce morbidity and other complications associated with malnutrition in some patients.
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Randomised Trial sentence examples within 3 Randomised Trial
recently reported interim data from the phase 3 randomised trial (KEYNOTE-426) that showed that the combination of pembrolizumab, an anti-PD-1 antibody and axitinib, a VEGFR inhibitor, appears to be superior to the traditional agent, sunitinib.
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The COV[ndash]BARRIER study overall trial results plus these COV[ndash]BARRIER addendum study data in mechanically ventilated and ECMO patients provide important information in context of other large, phase 3 randomised trials in participants with invasive mechanical ventilation at baseline.
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Randomised Trial sentence examples within Ongoing Randomised Trial
In asymptomatic patients, there may be a small increase in the risk of stroke or death within 30 days of treatment with CAS compared to CEA, but the currently available evidence is insufficient and further data from ongoing randomised trials are needed.
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Methods: As part of an ongoing randomised trial of CBD support in Stockholm, Sweden, semi-structured individual interviews were conducted with nine of the 35 participating CBDs.
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Randomised Trial sentence examples within Included Randomised Trial
We included randomised trials and cohort studies comparing HFNT with low-flow oxygen (LFO) or NIV.
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Evaluation of the effectiveness of contact investigation included randomised trials, while the yield of contact investigation (co-prevalent and incident TB and LTBI) was assessed in non-randomised studies.
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Randomised Trial sentence examples within Five Randomised Trial
Randomised Trial sentence examples within Scale Randomised Trial
Further studies in large-scale randomised trials are needed to confirm the beneficial effects of the metabolic drugs in cardiovascular medicine.
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Conclusion
This review reports the multitude of physical and psychological stressors that patients with ESRD face, highlights the positive role renal social workers can play in improving the psychosocial stressors in this patient group and the need for large-scale randomised trials to understand the role of renal social workers as part of a multidisciplinary care.
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Randomised Trial sentence examples within Centre Randomised Trial
This feasibility study met its pre-determined progression criteria; an application will therefore be prepared and submitted for funding for a fully-powered multi-centre randomised trial.
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Methods: The Objective Randomised Blinded Investigation with optimal medical Therapy of Angioplasty in stable angina (ORBITA) trial was the first blinded, multi-centre randomised trial of PCI vs.
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Randomised Trial sentence examples within One Randomised Trial
Study designs and methods were not always clearly described, but 74 (93%) were quantitative (including one randomised trial), five (6%) were mixed-methods, and one was qualitative.
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The eligible research varied widely in design, scope, reported outcomes and overall quality, with one randomised trial, two quasi-experimental studies, two longitudinal follow up studies, three systematic reviews and one observational study.
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Randomised Trial sentence examples within Individually Randomised Trial
METHODS
We did a participant-masked and observer-masked individually randomised trial in Lalitpur, Nepal, in which 20 019 children aged 9 months to younger than 16 years were randomly assigned in a 1:1 ratio to receive a single dose of TCV (Typbar TCV, Bharat Biotech International, India) or capsular group A meningococcal conjugate vaccine (MenA).
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We did a two-arm, individually randomised trial in 18 secondary state-funded schools across the Greater London area of the UK.
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Randomised Trial sentence examples within First Randomised Trial
Did the first randomised trial of faecal microbiotal transplantation in psoriatic arthritis have a negative outcome due to the paradoxical triggering of a reactive type arthritis disease flare? We read with great interest the report by Kragsnaes et al on faecal microbiota transplantation (FMT) in active psoriatic arthritis (PsA).