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10.1017/neu.2021.34

METHOD The study was designed as a double-blind randomised dose-response study of CGMP (with added leucine and tryptophan) in 15 healthy men, receiving 3 different doses of CGMP with an interval of at least 14 days.

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10.1136/bmjopen-2019-029348

Phase I is a non-randomised dose-escalation study using a Bayesian optimal interval design in which up to 16 patients will be enrolled to evaluate the safest and most efficacious dose for stabilising cholesterol levels.

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10.1136/ANNRHEUMDIS-2019-EULAR.3985

There is a need for randomised dose-reduction studies in axSpA and further research to understand the factors that lead to dose-reversion.

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Randomised Dose

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Mar 25, 2023

What is/are Randomised Dose?

Randomised Dose - METHOD The study was designed as a double-blind randomised dose-response study of CGMP (with added leucine and tryptophan) in 15 healthy men, receiving 3 different doses of CGMP with an interval of at least 14 days. ^[1] Phase I is a non-randomised dose-escalation study using a Bayesian optimal interval design in which up to 16 patients will be enrolled to evaluate the safest and most efficacious dose for stabilising cholesterol levels. ^[2] There is a need for randomised dose-reduction studies in axSpA and further research to understand the factors that lead to dose-reversion. ^[3]