Prognosis and long-term survival of HCC remain unsatisfactory, even after radical resection, and many non-invasive predictors have been explored for post-operative patients.
The inclusion criteria were as follows: (1) patients who underwent radical resection of gastric cancer plus D2 lymph node dissection and were confirmed as gastric adenocarcinoma by postoperative pathology and received immunohistochemical examination of neuroendocrine markers Syn and/or CgA; (2) patients aged 20 to 75 years with normal organ function; (3) patients who did not receive neoadjuvant chemotherapy or radiotherapy before operation; (4) patients with postoperative pathological stage I to III according to the 8th edition of tumor staging system of American Joint Committee on Cancer (AJCC); and (5) patients who completed adjuvant chemotherapy according to the postoperative pathological stage.
Background
This study aimed to identify potential biomarkers associated with locoregional recurrence in patients with esophageal squamous cell carcinoma (ESCC) after radical resection.
Background Although previous studies have discussed whether the minimally invasive esophagectomy (MIE) is superior to open surgery, the data concerning esophageal squamous cell carcinoma (ESCC) patients underwent neoadjuvant treatment followed by radical resection is limited.
For locally advanced rectal cancer patients, introducing neoadjuvant concurrent chemoradiotherapy (CCRT) before radical resection allows tumor downstaging and increases the rate of anus retention.
ConclusionsThe expression of KLK7 in patients with pancreatic ductal adenocarcinoma increased obviously, and it is directly related to the poor prognosis of patients after radical resection of pancreatic cancer.
CASE SUMMARY We report a case of successful radical resection with PD after neoadjuvant S-1 plus oxaliplatin (SOX) and trastuzumab in a patient (66-year-old male) with advanced gastric cancer invading the pancreatic head.
The study aimed to evaluate the effect of forced-air warming blanket combined with conventional thermal insulation measures on inadvertent perioperative hypothermia (IPH) in elderly patients undergoing laparoscopic radical resection of colorectal cancer.
Objective: To observe the efficacy and safety of S(+)-ketamine combined with sufentanil for patient-controlled intravenous analgesia (PCIA) in elderly patients undergoing laparoscopic radical resection of rectal cancer and explore its impact on patients' early recovery.
Transanal total mesorectal excision (taTME) is a novel radical resection technique that may address the unsatisfactory functional and oncological outcomes of medium‐low rectal cancers.
3% of patients received surgical intervention and both partial and radical resection were associated with significantly improved overall survival (P<0.
7% of patients received surgical intervention and both partial and radical resection were associated with significantly improved overall survival (P<0.
A large number of studies have demonstrated that GC patients are characterized by higher morbidity, metastasis rates, and mortality and lower early diagnosis rates, radical resection rates, and 5-year survival rates.
To investigate the role of indocyanine green (ICG) lymphangiography in the reduction of chyle fistula formation after radical resection of right colon cancer.
Objective
To compare and analyze the clinical effect of two kind of approaches: caudal approach and central approach in laparoscopic radical resection of right colon cancer.
Objective Platelet–lymphocyte ratio (PLR)’s effects on recurrence-free survival (RFS) and overall survival (OS) were evaluated in individuals undergoing radical resection for advanced hypopharyngeal squamous cell carcinoma (HSCC).
Background There are no standard therapeutic strategies for local lymph node (LN) recurrence after radical resection of oesophageal squamous cell carcinoma (ESCC), and prognostic risk factors remain controversial.
Background We compared the advantages and disadvantages of modified triangular anastomosis and tubular anastomosis for digestive tract reconstruction in patients undergoing laparoscopic-assisted radical resection of right colon cancer.
Methods
the retrospective cohort data was derived from the First Affiliated Hospital of Zhengzhou University from January 2014 to December 2018 on 496 patients who underwent radical resection of HCC with staging I-II.
The inclusion criteria were as follows: (1) patients who underwent radical resection of gastric cancer plus D2 lymph node dissection and were confirmed as gastric adenocarcinoma by postoperative pathology and received immunohistochemical examination of neuroendocrine markers Syn and/or CgA; (2) patients aged 20 to 75 years with normal organ function; (3) patients who did not receive neoadjuvant chemotherapy or radiotherapy before operation; (4) patients with postoperative pathological stage I to III according to the 8th edition of tumor staging system of American Joint Committee on Cancer (AJCC); and (5) patients who completed adjuvant chemotherapy according to the postoperative pathological stage.
Background Although laparoscopic radical resection (LLR) has long been contraindicated in gallbladder cancer (GBC), recent studies have demonstrated laparoscopic surgery did not adversely affect the perioperative and survival outcomes of GBC patients.
Objective: To explore the surgical method and the clinical efficacy of complete retroperitoneal laparoscopic radical resection of upper tract urothelial carcinoma (UTUC).
Methods NSCLC patients undergoing radical resection and subsequent adjuvant chemotherapy from 2013 to 2017 at Sun Yat-sen University Cancer Center were retrospectively reviewed.
147; prospective multi-center observational study), patients with cT3 rectal cancer <12 cm from the anal verge with a negative (>1 mm) MRI-assessed CRM undergoing radical resection from 2006 to 2008 were selected.
Methods This retrospective cohort study enrolled stage I to III rectal cancer patients without preoperative therapy (N = 1,022) who received radical resection of rectal cancer from 2 hospitals in China.
Following radical resection of the lung cancer, noncaseating granulomas were observed in both lung tissues and lymph nodes, which resulted in a diagnosis of echinoderm microtubule-associated protein-like 4-ALK positive NSCLC accompanied with sarcoidosis.
The patient then underwent thoracoscopic radical resection of the right upper lung cancer under general anesthesia and recovered uneventfully after surgery.
He underwent a thoracoscopic radical resection followed by four cycles of adjuvant chemotherapy but relapsed 2 months after completing the chemotherapy.
The aim of this study is to determine whether adjuvant radiotherapy can improve survival of locally advanced EGJ adenocarcinoma after D2 radical resection.
Methods and materials Data from 785 patients with gastric adenocarcinoma who had undergone D1/D2 radical resection and adjuvant chemotherapy were collected, the site of first progression was determined, and the relationship between the rate of local recurrence and clinicopathologic features was analyzed.
After radical resection of the left renal tumor, postoperative pathology confirmed complete tumor remission and tumor-like xanthogranulomatous pyelonephritis.
Inclusion criteria: (1) Standard neoadjuvant therapy before operation; (2) Laparoscopic rectal cancer radical resection was performed; (3) During the operation, the protective enterostomy was performed including transverse colostomy and ileostomy; (4) The patients were followed up regularly; (5) Clinical data was complete.
All patients had undergone radical resection for primary CRC and administered with standard systemic therapy regimens (seven for the first line and 10 for the second line).
Some advanced tumors may require radical resections; however, extensive, high-risk surgery may be justified by the indolent biology of the disease and the likelihood of cure.
For locally advanced gastric NEC, it has not been reported whether neoadjuvant chemotherapy or neoadjuvant chemoradiotherapy could reduce tumor stage and improve radical resection rate.
It is in these patients that perioperative chemotherapy has helped improve radical resection rates control preoperative micrometastases and improve survival.
We investigated the analgesic effects of US-guided posterior TAPB with RSB on postoperative pain following laparoscopy-assisted radical resection of early-stage rectal cancer.
Objective: To examine the safety and effectiveness of a novel stent assisted intestinal bypass for preventing anastomotic leakage in laparoscopic assisted radical resection of rectal cancer.
En-bloc radical resection of the gallbladder cancer, including partial colectomy and hepatectomy with regional node dissection, followed by colocolostomy and Roux-en-Y choledochojejunostomy, was successfully performed.
En-bloc radical resection of the gallbladder cancer, including partial colonectomy and hepatectomy with regional node dissection, followed by colocolostomy and Roux-en-Y choledochojejunostomy, was successfully performed Pathology analysis indicated an adenosquamous carcinoma with positive adenocarcinoma marker (CK7, CK19) and squamous carcinoma markers (CK5/6, P63).
Methods: The data of 135 patients with IHCC who were admitted to the Department of Hepatopancreatobiliary Surgery,Second Affiliated Hospital of Zhejiang University School of Medicine from November 2011 to November 2020 after discussion by a multidisciplinary team and planned to undergo radical resection were analyzed retrospectively.
Establishing the diagnosis is fundamentally based on the characteristic pathological and immunohistochemical studies, for the only available cure modality by complete radical resection to be promptly offered.
The observation group was treated with TAC scheme, neoadjuvant chemotherapy combined with modified radical resection, and continuously treated with the same scheme after operation until the end of the course of treatment.
Material and methods Sample collection and tissue culture in vitro In our study, the HCC tissue group, the adjacent noncancerous tissue (AN) group, and the distal noncancerous tissue (DN) group were obtained from 2 primary HCC patients who were diagnosed with HCC by post-operative pathological examinations and subjected to standard radical resection.
Lessons: Radiological imaging studies are insufficient for the differential diagnosis of abdominal mass from other diseases, whereas surgery is the only radical treatment method, and the preferred surgical method is still active radical resection of the tumor.
Therefore, preoperative and intraoperative identification of suspicious malignant cases, active radical resection of the lesions and comprehensive medical treatment have important implications for the prognosis of patients.
These tumors are typically extensive and infiltrative at the time of presentation, requiring radical resection to achieve margins and obtain local tumor control.
Development of tumor-targeting strategies for FGS can improve the chance of achieving radical resection of tumors with clear surgical margins and inclusion of occult foci of disease.
The goal of rectal cancer treatment should be to better protect organ function and improve patients' quality of life on the basis of ensuring radical resection.
1 The surgical approach should be tailored to the clinical and anatomic findings to achieve radical resection, preferably total removal of the content and the capsule to prevent recurrences.
For locally advanced gastric NEC, it has not been reported whether neoadjuvant chemotherapy or neoadjuvant chemoradiotherapy could reduce tumor stage and improve radical resection rate.
It is in these patients that perioperative chemotherapy has helped improve radical resection rates control preoperative micrometastases and improve survival.
RE cases were divided according to different treatment methods into a radical resection group (Group A, 31 cases), a non-radical resection group (Group B, 37 cases), and a non-surgical group (Group C, 53 cases).
He underwent a thoracoscopic radical resection followed by four cycles of adjuvant chemotherapy but relapsed 2 months after completing the chemotherapy.
Radical Resection -
The adjuvant treatment, either chemotherapy or radiotherapy, can be considered when radical resection could not be achieved and if reoperation for a recurrence is not applicable.[1]We presented here a case of locally advanced minor salivary gland cancer that was treated by radical resection, reconstruction, and adjuvant radiation therapy at Vietnam National Cancer Hospital and had promising outcomes.[2]Patient concerns: Two lung adenocarcinoma patients with EGFR mutations who recurred after radical resection transformed into SCLC under treatment with the sequential first- and third-generation EGFR-TKIs.[3]The aim of the study is to evaluate the utility of the free flap reconstruction of the defects resulting from radical resection of these tumors in a single institution.[4]As the majority of patients experiences locoregional relapse and/or distant metastasis even after radical resection of esophageal cancer, many efforts have been made and are ongoing to identify the optimal multimodality treatment strategy.[5]The comprehensive treatment method consists of radical resection combined with postoperative radiotherapy and chemotherapy.[6]These strategies include accurate staging, excellent surgical technique, artery-first approaches to dissection, radical resections including arterial and multi-visceral resections, stereotactic radiation therapy and dose-escalation techniques, irreversible electroporation, and neoadjuvant chemotherapy with or without radiotherapy therapy.[7]Multivisceral (allo-) transplantation should be considered when radical resection of a benign tumor is likely to compromise portal flow and possibly precipitate acute liver failure, but it may be associated with a long waitlist time and tumor progression.[8]There was significant improvement in radical resection (R0) of metastases (OR 1.[9]Considering clinicopathological features and recurrence patterns, a systematic treatment plan, including radical resection and adjuvant treatment, should be established for hepatic-side GBC.[10]He had a medical history of radical resection for prostate cancer.[11]CONCLUSIONS
The present series shows that a radical resection of HPC can be achieved under the difficult anatomical conditions of skull base surgery.[12]In this study, we aimed to analyze the frequency of and risk factors for lymph node metastasis proven by histopathologic examination after radical resection.[13]Radical resection is paramount for curative oncological surgery.[14]
Conclusions: The FFOCF, in reconstruction surgery of advanced oral cavity carcinoma permits more radical resection of tumour with good functional as well aesthetic outcome.
[15]METHODS
Consecutive patients with LARC who received nCRT followed by radical resection between 2011 and 2016 were identified.[16]The ongoing INFINITY proof-of-concept study may provide evidence on immunotherapy and the potential omission of surgery in localized/locally advanced GC/GEJC patients selected for dMMR/MSI-high status eligible for radical resection.[17]Radical resection may improve the OS and CCS of glioblastoma patients aged ≥ 75 years and decrease early mortality.[18]CONCLUSIONS
The new T-stage classification system described herein can better differentiate prognostic outcomes after radical resection in patients with ampullary carcinoma by incorporating tumor size and depth of tumor infiltration.[19]Radical resection with or without adjuvant chemotherapy is a common option for stage II and III colorectal cancer.[20]Endoscopic ultrasonography-guided histological verification using biopsy and examining the drugs after organ-sparing and radical resection interventions was obtained in all 101 patients (100%) with pancreatic adenocarcinoma, and in 32 (61.[21]Methods The clinical data of 84 patients suffered from urinary retention after radical resection of cervical cancer (December 2018–December 2019) in the oncology department of Jinan Municipal Hospital of Traditional Chinese Medicine were selected for retrospective analysis.[22]Thus, it is imperative to consider both the technical resectability of liver lesions along with the underlying tumor biology in order to weigh the benefit of radical resection for CRLM.[23]Purpose: Five-aminolevulinic acid (5-ALA) is widely used as an intraoperative fluorescent probe for radical resection of high-grade glioma, and thus aids in extending progression-free survival of patients.[24]CONCLUSIONS
Radical resection with wide safety margins of normal tissues including neck dissection is the mainstay of treatment modality.[25]The laparoscopic-assisted pull-through procedure with radical resection from the distal rectum to the most proximal margin of the diseased skip segment is safe and effective in treating patients with SSHD.[26]LFT has a potential to play an essential role to prevent postoperative wound problem and lymphedema recurrence after radical resection of fibrotic tissue.[27]Two months before the admission, he underwent a radical resection for cancer of the left colon due to progressive abdominal distension and abdominal pain for 1 month.[28]Conclusion: Change in skeletal muscle mass during adjuvant chemotherapy can be incorporated into predictive prognostic nomograms for RFS and OS in GC patients after radical resection.[29]The objective of this study was to investigate the significance of RDW in patients with intrahepatic cholangiocarcinoma (ICC) after radical resection.[30]Summary Background The long-term effects of radical resection on quality of life may influence the treatment selection.[31]CONCLUSION
For select distal tibial sarcomas, after neoadjuvant chemotherapy pretreatment and radical resection, reconstruction using an endoprosthesis as a radical surgery provides an option was associated with a low rate of short-term local complications and relatively good early function.[32]In this edition of the Journal, Aphram and colleagues present their approach to radical resection and reconstruction of the aortic root, aortomitral continuity, and both valves in a challenging case of double prosthetic valve endocarditis.[33]Many kinds of complex laparoscopic procedures can be routinely performed at present, but radical resection of hilar cholangiocarcinoma (HC) by laparoscopy is still highly contentious.[34]After a multidisciplinary discussion, a radical resection of the abdominal wall tumor, total annex-hysterectomy, and bilateral iliac and inguinal lymphadenectomy was performed.[35]Conclusions The nomogram may be used to predict the prognosis of radical resection for adenocarcinoma of the pancreatic head.[36]A total of 1,021 patients diagnosed with lung cancer that was unsuitable for radical resection or radiation were enrolled and followed up for two years.[37]Results: Between April, 2015, and July, 2020, 140 patients were enrolled, and 54 patients withdrew due to colon obstruction (16), perforation (1), disease progression (22), death (1), radical resection (3), or other reasons (11).[38]Radical resection is inevitable for adequate curative therapy of AE and provides clear margins.[39]The purpose of our study was to compare the oncologic outcomes between local excision and radical resection in ypT0-1 patients and verify the oncologic safety of local excision.[40]PURPOSE
To estimate the prognostic value of preoperative combi-elastography for early recurrence (ER) of hepatocellular carcinoma (HCC) after radical resection.[41]For treatment, radical resection was performed in 57.[42]Radical resection was performed
in 50% patients, whereas 47% patients underwent a subtotal resection.[43]In the valuable study, they concluded that primary cystic duct carcinoma (CDC) is a locally advanced disease with aggressive characteristics pathologically, and radical resection are recommended for these patients.[44]Background: 5-Fluoruracil based adjuvant chemotherapy after radical resection is recommended for stage IIcolon cancer patients with high risk of recurrence.[45]She received S-1 monotherapy for 6 months, and no recurrence has been detected at 1 year after radical resection.[46]Condition after non-adjuvant PCT and radical resection of the right breast.[47]Radical resection is the gold standard of treatment in most cases of colorectal cancer, with a high rate of postoperative complications.[48]RESULTS
Radical resection (RR) was defined as either gross total resection (GTR) or near total resection NTR (90-100% of the tumor).[49]False endoscopic diagnosis and subsequent treatment may lead to non-radical resection and metastases.[50]
The inclusion criteria were as follows: (1) patients who underwent radical resection of gastric cancer plus D2 lymph node dissection and were confirmed as gastric adenocarcinoma by postoperative pathology and received immunohistochemical examination of neuroendocrine markers Syn and/or CgA; (2) patients aged 20 to 75 years with normal organ function; (3) patients who did not receive neoadjuvant chemotherapy or radiotherapy before operation; (4) patients with postoperative pathological stage I to III according to the 8th edition of tumor staging system of American Joint Committee on Cancer (AJCC); and (5) patients who completed adjuvant chemotherapy according to the postoperative pathological stage.[1]Background Systematic lymph node dissection is an important part of radical resection for lung cancer.[2]A total of 374 cIA lung adenocarcinoma patients who had undergone thoracoscopic radical resection with Systematic mediastinal lymph node dissection (SMLD) in the Department of Thoracic Surgery of the Affiliated Hospital of Qingdao University between January 2018 to January 2020 were retrospectively reviewed.[3]All patients underwent an anatomical radical resection and mediastinal lymph node dissection.[4]At present, the Da Vinci Robot System can be used for almost any intracavitary urology surgery, including adrenal surgery, kidney surgery (radical nephrectomy, live donor nephrectomy, and partial nephrectomy), ureteropelvic surgery (pyeloplasty, radical resection of ureteral cancer), bladder surgery (radical cystectomy, partial cystectomy), prostate surgery (radical prostatectomy, simple prostatectomy), abdominal and pelvic lymph node dissection, etc.[5]The patient underwent radical resection and lymph node dissection, which revealed positive margins and ten of forty-six positive lymph nodes.[6]We performed radical resection of the right axilla, including the scar, and axillary lymph node dissection.[7]The secondary observational outcomes were duration of needle biopsy, operation duration, volume of intraoperative hemorrhage, rate of postoperative wound infection, rate of abdominal cavity infection, length of stay, and number and positivity of lymph node dissections after laparoscopic radical resection of colon cancer.[8]After diagnosis of a pleural metastasized TC mixed with SP, radical resection and systemic lymph node dissection were performed.[9]
CASE SUMMARY We report a case of successful radical resection with PD after neoadjuvant S-1 plus oxaliplatin (SOX) and trastuzumab in a patient (66-year-old male) with advanced gastric cancer invading the pancreatic head.[1]In this case report, a 73-year-old male patient received radical resection for rectal carcinoma in January 2010.[2]CASE SUMMARY A 73-year-old male had undergone extended radical resection for rectosigmoid cancer.[3]A 35-year-old male with a history of radical resection done for SCC of the buccal mucosa followed by postoperative chemoradiotherapy presented with complaints of headache and convulsions accompanied by severe low backache and left lower limb radiculopathy with no motor or sensory deficit.[4]
A large number of studies have demonstrated that GC patients are characterized by higher morbidity, metastasis rates, and mortality and lower early diagnosis rates, radical resection rates, and 5-year survival rates.[1]Radical resection of colorectal liver metastases (CRLM) offers the