Introduction to Polymeric Nanoparticles
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Polymeric Nanoparticles sentence examples within drug delivery system
Polymeric nanoparticles were found to be an effective drug delivery system to improve the bioavailability of drugs by increasing their solubility and circulation half-life in comparison with pure cefixime.
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The use of drug delivery systems based on nanoparticles as liposomes, dendrimers, cationic nanoemulsions, polymeric nanoparticles pointing out the advantages of the proposed nanomedicines to target this ocular disease.
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Polymeric Nanoparticles sentence examples within lipid nanoparticles nanostructured
Recently, nanoformulations that include nanovesicles, solid-lipid nanoparticles, nanostructured lipid carriers, nanoemulsions, and polymeric nanoparticles have shown promising outcomes in improving the efficacy and bioavailability of vitamin E.
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More specifically, nanocarotenoids were prepared from both carotenoid extracts and standards by employing various preparation techniques to yield different nanostructures including nanoemulsions, nanoliposomes, polymeric/biopolymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid nanoparticles, supercritical fluid-based nanoparticles and metal/metal oxide nanoparticles.
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Polymeric Nanoparticles sentence examples within liposomes solid lipid
Liposomes, solid-lipid nanoparticles, dendrimers, polymeric nanoparticles, mesoporous silica nanoparticles, inorganic nanoparticles, nanotubes, quantum dots, and nanofibers are nanocarriers that are proved too smart nano-based drug delivery system.
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These include micelles, emulsions, liposomes, solid lipid nanoparticles, polymeric nanoparticles, microspheres, dendrimers, and solid dispersions.
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Polymeric Nanoparticles sentence examples within targeted drug delivery
Polymeric Nanoparticles sentence examples within polylactic co glycolic
The aim of this work was to develop polymeric nanoparticles (NPs) of poly(lactic-co-glycolic acid) (PLGA) and polyethylene glycol (PEG) loaded with CFZ and functionalized with a transferrin receptor (TfR)-binding peptide, aiming brain drug delivery for CNS-TB treatment by the intravenous route.
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In order to boost anticancer efficacy of indocyanine green (ICG)-mediated photothermal therapy (PTT) by promoting intracellular ICG delivery, the ICG-carrying hybrid polymeric nanoparticles were fabricated in this study by co-assembly of hydrophobic poly(lactic-co-glycolic acid) (PLGA) segments, ICG molecules, amphiphilic tocopheryl polyethylene glycol succinate (TPGS) and pH-responsive methoxy poly(ethylene glycol)-benzoic imine-1-octadecanamine (mPEG-b-C18) segments in aqueous solution.
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Polymeric Nanoparticles sentence examples within polyethylene glycol b
In brief, a small interfering RNA targeting SIRPα (siSIRPα) and a STING agonist (cGAMP) were co-delivered into APCs by the encapsulation into poly(ethylene glycol)-b-poly(lactide-co-glycolide)-based polymeric nanoparticles (NPsiSIRPα/cGAMP).
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In this study, integrin-mediated targeting and near-infrared fluorescence (NIRF) traceable polyethylene glycol-b-poly(lactic-co-glycolic acid) (PEG-PLGA)-based polymeric nanoparticles (NPs) were prepared to investigate the effects of paclitaxel (PTX) and curcumin (CUR) combination therapy on breast cancer.
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Polymeric Nanoparticles sentence examples within nanostructured lipid carrier
This results in the emergence of numerous novel nanomaterials and its composite products into the market such as liposome, polymeric nanoparticles, dendrimers, and nanostructured lipid carrier.
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In this paper, we give an overview of the most recent developments of different nanosystems including nanocrystals/nanosuspensions, solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), polymeric nanoparticles (PNPs), self-nanoemulsifying drug delivery systems (SNEDDSs), nanoemulsions, liposomes, niosomes, micelles, mesoporous silica nanoparticles (MSNs), dendrimers and cyclodextrin (CD)-based nanosponges currently investigated as the absorption enhancement strategy for the oral route.
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Polymeric Nanoparticles sentence examples within superparamagnetic iron oxide
Nanoscale platforms is including polymeric nanoparticles, polymeric nanoconjugates, carbon nanotubes, peptides and proteins, superparamagnetic iron oxide nanoparticles, endohedral metallofullerene nanoparticles, fullerenes, nanodiamonds, micelles, and dendrimers.
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Magnetic polymeric nanoparticles (MPNPs), a cluster of magnetic nanoparticles (MNPs) or superparamagnetic iron oxide nanoparticles embedded into a poly(styrene27-b-acrylic acid120) P(S27-b-AA120) p.
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Polymeric Nanoparticles sentence examples within epidermal growth factor
Methods Nanotechnological procedures were applied to entrap cisplatin at high efficacy into polymeric nanoparticles (PNPs) that were conjugated on their surface with the epidermal growth factor receptor (EGFR) selective and cell-internalizing CL4 aptamer to improve targeted therapy.
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Methods: Nanotechnological procedures were applied to entrap cisplatin at high efficacy into polymeric nanoparticles (PNPs) that were conjugated on their surface with the epidermal growth factor receptor (EGFR) selective and cell-internalizing CL4 aptamer to improve targeted therapy.
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Polymeric Nanoparticles sentence examples within carbon nanotubes quantum
Nanomaterials such as gold nanoparticles, carbon nanotubes, quantum dots, lipids, and polymeric nanoparticles represent novel sources to target CVDs.
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In this chapter, the most important and recent progress in the encapsulation of anticancer medicines is examined: methods of preparation of distinct nanoparticles (inorganic nanoparticles, dendrimers, biopolymeric nanoparticles, polymeric micelles, liposomes, polymersomes, carbon nanotubes, quantum dots, and hybrid nanoparticles), drug loading and drug release mechanisms.
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Polymeric Nanoparticles sentence examples within co glycolic acid
Methods: The acyclovir containing Poly Lactic- Co-Glycolic Acid based polymeric nanoparticles were prepared by using nanoprecipitation technique and the optimized formulation was evaluated for particle size, encapsulation efficiency, in vitro release study, Differential Scanning Calorimetry, X-Ray Diffraction, Scanning Electron Microscopy, redispersibility, swelling index, ex vivo study and stability studies.
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To address these aforementioned clinically significant issues, we report dual functioning DADS loaded polymeric nanoparticles composed of a combination of Eudragit S100 (ES100) as a pH-sensitive polymer for targeted delivery to colon and poly (lactic-co-glycolic acid) (PLGA) as a biodegradable polymer for sustained release of DADS along with their physicochemical characteristics.
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Polymeric Nanoparticles sentence examples within Loaded Polymeric Nanoparticles
This study aims to evaluate the antitumoral effect of PHT-427-loaded polymeric nanoparticles based on α-tocopheryl succinate (α-TOS).
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Present study is designed to fabricate APO loaded polymeric nanoparticles (APO-NPs) to enhance its therapeutic efficacy and sustainability in the biological system.
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Polymeric Nanoparticles sentence examples within Biodegradable Polymeric Nanoparticles
Biodegradable polymeric nanoparticles perform to be a favorable environment-responsive controlled drug release system.
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Overall, our results indicated porphyrin-doped biodegradable polymeric nanoparticles act as effective phototherapeutic agents against a broad range of cancer cell lines and microbes upon activation by the low-cost LED light.
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Polymeric Nanoparticles sentence examples within Fluorescent Polymeric Nanoparticles
We have developed fluorescent polymeric nanoparticles loaded with temperature-sensitive units (as rhodamine B) and internal reference units (as coumarin) for imaging and ratiometric sensing of the cellular temperature in the physiological range.
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Under the synergistic action of difunctional segments, PEN was endowed with the assembled fluorescent polymeric nanoparticles (FPNs) though the coordination effect between metal ions and carboxyl group with much higher emission efficiently.
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Polymeric Nanoparticles sentence examples within Targeted Polymeric Nanoparticles
In this report, we present for the first time, a full spectrum characterization of transferrin receptor 1 (TfR1)-targeted polymeric nanoparticles (abbreviated, P2Ns-GA) that do not compete with endogenous transferrin, and serve as a versatile platform for oral drug delivery.
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Collagen-IV-targeted polymeric nanoparticles, loaded with the ANXA1 biomimetic peptide Ac2-26 (Ac2-26-NPs), were synthesized and administered perioperatively during colitis induction.
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Polymeric Nanoparticles sentence examples within Spherical Polymeric Nanoparticles
The hydrophilic nanocomposite membranes were composed of spherical polymeric nanoparticles (NPs) synthesized through polymerization-induced self-assembly (PISA) with iron oxide NPs coated with quaternized poly(2-dimethylamino)ethyl methacrylate.
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Due to the poor solubility of curcumin in biological fluids, we used spherical polymeric nanoparticles as carriers (SPN-curc) to optimize its uptake by MSCs.
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Polymeric Nanoparticles sentence examples within Prepared Polymeric Nanoparticles
The effect of the functionalisation in the micelle’s physical properties was elucidated, and the antibacterial and antibiofilm activities were assessed for the prepared polymeric nanoparticles against Pseudomonas spp.
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The Scanning Electron Microscope (SEM) was used to determine the shape and size of the prepared polymeric nanoparticles and the average nanoparticle size counted by the Image-J program.
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Polymeric Nanoparticles sentence examples within Assembled Polymeric Nanoparticles
Because hydrophobic parts of the polymer can interact with hydrophobic parts of the TCA, the TCA was encapsulated into the self-assembled polymeric nanoparticles.
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This paper highlights the potential benefits of using self-assembled polymeric nanoparticles of various shapes to enhance drug uptake.
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Polymeric Nanoparticles sentence examples within Magnetic Polymeric Nanoparticles
Magnetic polymeric nanoparticles (MPNPs), a cluster of magnetic nanoparticles (MNPs) or superparamagnetic iron oxide nanoparticles embedded into a poly(styrene27-b-acrylic acid120) P(S27-b-AA120) p.
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Moreover, curcumin (Cur), a potential agent for GBM treatment, was loaded into the magnetic polymeric nanoparticles (m-PNPs) with a loading capacity of 8% (w/w, Cur/NPs) and a mean diameter of Cur-loaded m-PNPs (Cur-m-PNPs) was 142±70 nm.
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Polymeric Nanoparticles sentence examples within Novel Polymeric Nanoparticles
OBJECTIVE
To investigate the effect of novel polymeric nanoparticles (NPs) doped with melatonin (ML) on nano-hardness, crystallinity and ultrastructure of the formed hydroxyapatite after endodontic treatment.
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OBJECTIVES
To investigate the effectiveness of novel polymeric nanoparticles (NPs) doped with melatonin (ML) in reducing dentin permeability and facilitating dentin remineralization after endodontic treatment.
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Polymeric Nanoparticles sentence examples within Responsive Polymeric Nanoparticles
Polymeric Nanoparticles sentence examples within Stable Polymeric Nanoparticles
Introduction: Dendrimers are highly branched, stable polymeric nanoparticles with functional groups capable of binding other molecules and may increase delivery of chemicals into skin.
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In this paper, highly stable polymeric nanoparticles were fabricated via a coordination strategy between Cu(II) and carboxylic groups in poly(ethylene glycol)- b-poly(ester-carbonate) (PEC) for efficient loading of Cu(DDC)2, which was generated by the in situ reaction of DSF and Cu(II).
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Polymeric Nanoparticles sentence examples within Conjugated Polymeric Nanoparticles
A fluorescent sensor array-based electronic tongue consisting of 6 soluble conjugated polymeric nanoparticles (SCPNs) embedded in waterborne polyurethane was developed for 9 tea discrimination.
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In the present study, ApoE3 conjugated polymeric nanoparticles derived from di-block copolymer methoxy poly(ethyleneglycol)-polycaprolactone (mPEG-PCL) have been used to boost the delivery of donepezil to the brain.
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Polymeric Nanoparticles sentence examples within Functional Polymeric Nanoparticles
This work reports on itraconazole (ITZ) encapsulated into functional polymeric nanoparticles for their targeted and controlled release into macrophages to fight intracellular infections.
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The relatively high concentration and potential scalability makes it a promising technique for industrial production and practical applications of functional polymeric nanoparticles.
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Polymeric Nanoparticles sentence examples within Shell Polymeric Nanoparticles
Core-shell polymeric nanoparticles, bacterial cellulose/chitosan membranes, and biocomposites were independently loaded with silver sulfadiazine, a well-known sulfonamide antibacterial agent used in the therapy of mild-to-moderate infections for sensitive organisms.
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Herein, we propose a novel type of biodegradable antiangiogenic core-shell polymeric nanoparticles (NPs) for the delivery of poorly water-soluble chemotherapeutics.
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Polymeric Nanoparticles sentence examples within Containing Polymeric Nanoparticles
Polymeric Nanoparticles sentence examples within Functionalized Polymeric Nanoparticles
This limitation is bypassed by apolipoprotein E (ApoE)‐functionalized polymeric nanoparticles (NPs) that are able to transport drugs (e.
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The nanotechnology approaches like functionalized polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carrier, nanoemulsion, liposomes, transferosomes, and carbon nanotubes which have been recently evaluated for treatment or detection of bacterial meningitis have been focused.
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Polymeric Nanoparticles sentence examples within Form Polymeric Nanoparticles
Sulfobutyl ether derivative of β-cyclodextrin, cross-linked in the presence of antibacterial drug moxifloxacin, forms polymeric nanoparticles (50–150 nm in diameter), with highly efficient (up to 85%) encapsulation of the drug.
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Both PTH and ACR were covalently attached to amphiphilic polymers that are designed to form polymeric nanoparticles with hydrodynamic diameter DH ranging between 5 and 11 nm in aqueous solution.
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Polymeric Nanoparticles sentence examples within Shaped Polymeric Nanoparticles
Polymeric Nanoparticles sentence examples within Biocompatible Polymeric Nanoparticles
Biocompatible polymeric nanoparticles, liposomes and hybrid nanosystems have been thoroughly discussed.
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