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Phase Trial sentence examples within Early Phase Trial



Opções Contemporâneas de Rastreio da Cardiotoxicidade Relacionada a Tratamentos Oncológicos



Trends in Clinical Benefits and Costs of Novel Therapeutics in AML: at What Price Does Progress Come?


Phase Trial sentence examples within Late Phase Trial



Choosing primary endpoints for clinical trials of health care interventions



Cardioplegia practice in paediatric cardiac surgery: a UK & Ireland survey


Phase Trial sentence examples within Later Phase Trial



A third trial oversight committee: Functions, benefits and issues



Novel tyrosine kinase inhibitors for patients with inadequate response in chronic myeloid leukemia



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Phase Trial sentence examples within Clinical Phase Trial



Natural Bioactive Cyclic Peptides and Peptidomimetics



[Efficacy of Hedgehog inhibitors in acute myeloid leukemia and establishment of valid biomarkers].


Phase Trial sentence examples within phase trial result



Treatment strategy for patients with platinum-sensitive ovarian cancer using PARP inhibitors



PARP inhibitors for BRCA wild type ovarian cancer; gene alterations, homologous recombination deficiency and combination therapy.


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Endpoints and patient stratification in clinical trials for alcoholic hepatitis.



Delayed immune-related adverse events in assessment for dose-limiting toxicity in early phase immunotherapy trials.


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10.1016/s0735-1097(19)33219-x

PERICARDIAL EFFUSION WITH TAMPONADE PHYSIOLOGY AS AN IMMUNE-RELATED ADVERSE EVENT SECONDARY TO NIVOLUMAB


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10.32635/2176-9745.rbc.2019v65n3.388

Opções Contemporâneas de Rastreio da Cardiotoxicidade Relacionada a Tratamentos Oncológicos


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10.1016/S1470-2045(19)30691-6

Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials.


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10.1177/1740774519890146

Designing and evaluating dose-escalation studies made easy: The MoDEsT web app


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10.1007/s11899-019-00510-2

Trends in Clinical Benefits and Costs of Novel Therapeutics in AML: at What Price Does Progress Come?


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10.1093/annonc/mdz426.009

Incorporation of correlative studies in ovarian cancers in the era of precision medicine: Assessment of accountability and utility


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10.1158/1535-7163.TARG-19-A080

Abstract A080: Olaparib and the ATR inhibitor AZD6738 in relapsed, refractory cancer patients with homologous recombination (HR) repair mutations – OLAPCO



Maintaining a fit T‐cell compartment: lymphoma treatment sequencing in the era of chimeric antigen receptor T‐cell therapies


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10.1177/1740774519881619

A third trial oversight committee: Functions, benefits and issues


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10.1016/j.conctc.2019.100461

2D (2 Dimensional) TEQR design for Determining the optimal Dose for safety and efficacy


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10.1016/j.conctc.2019.100486

Choosing primary endpoints for clinical trials of health care interventions


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10.3390/ijms20215344

Autosomal Dominant Retinitis Pigmentosa Due to Class B Rhodopsin Mutations: An Objective Outcome for Future Treatment Trials


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10.1080/00207454.2018.1481066

Sativex® as add-on therapy vs. further optimized first-line ANTispastics (SAVANT) in resistant multiple sclerosis spasticity: a double-blind, placebo-controlled randomised clinical trial


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10.1016/j.vaccine.2019.04.056

Simian adenovirus vector production for early-phase clinical trials: A simple method applicable to multiple serotypes and using entirely disposable product-contact components


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10.1136/archdischild-2018-315237

Parents’ and children’s comprehension and decision in a paediatric early phase oncology trial: a prospective study


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10.1016/J.EUO.2019.01.002

Effect of Immunotherapy on Local Treatment of Genitourinary Malignancies.


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10.1093/annonc/mdz336

Treatment strategy for patients with platinum-sensitive ovarian cancer using PARP inhibitors


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10.1177/1740774519890145

Adaptive dose-finding based on safety and feasibility in early-phase clinical trials of adoptive cell immunotherapy


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10.4103/ijmpo.ijmpo_87_18

Selective cyclin-dependent kinase 4/6 inhibitors as anticancer drugs: Moving beyond hormone receptor-positive breast cancer


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10.3389/fpsyt.2019.00846

A Proof-of-Mechanism Study to Test Effects of the NMDA Receptor Antagonist Lanicemine on Behavioral Sensitization in Individuals With Symptoms of PTSD


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10.1186/s12967-019-02154-5

A few ethical issues in translational research for gene and cell therapy


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10.1182/bloodadvances.2018026211

Inotuzumab: from preclinical development to success in B-cell acute lymphoblastic leukemia.


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10.21037/cco.2019.05.02

The value of networks in driving phase I trials: the Peter MacCallum Cancer Centre experience.



Spotlight on itolizumab in the treatment of psoriasis – current perspectives from India


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10.1177/0267659118794343

Cardioplegia practice in paediatric cardiac surgery: a UK & Ireland survey


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10.1016/j.ejca.2019.08.002

Clinical efficacy of the optimal biological dose in early-phase trials of anti-cancer targeted therapies.


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10.1016/j.ymthe.2019.05.015

Effect of Cryopreservation on Autologous Chimeric Antigen Receptor T Cell Characteristics.


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10.1109/ICORT46471.2019.9069655

Artillery Gun Recoil Measurement Using High-Speed Imaging and Image Processing Technique


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10.1007/s10637-019-00879-0

Factors affecting symptom presentation in an early-phase clinical trials clinic patient population


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10.1080/21645515.2019.1688040

Prevalent levels of RSV serum neutralizing antibodies in healthy adults outside the RSV-season


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10.1016/j.hlc.2019.04.014

Status of PCSK9 Monoclonal Antibodies in Australia.


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10.1186/s13045-019-0733-6

Ataxia telangiectasia and Rad3-related inhibitors and cancer therapy: where we stand


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10.1016/S1470-2045(19)30151-2

Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial.


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10.1016/j.eururo.2018.07.027

Systematic Review of Systemic Therapies and Therapeutic Combinations with Local Treatments for High-risk Localized Prostate Cancer.


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10.1016/j.vaccine.2019.09.048

Barriers and motivations for participation in preventive vaccine clinical trials: Experience of 5 clinical research sites.


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10.1016/j.jhep.2018.11.005

Endpoints and patient stratification in clinical trials for alcoholic hepatitis.


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10.1093/icvts/ivy199

Cardioplegia in paediatric cardiac surgery: a systematic review of randomized controlled trials.


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10.1590/15174522-02105004

Shaping stem cell therapies in Argentina: regulation, risk management and innovation policies


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10.1007/s12072-019-09935-6

End-points for drug treatment in NASH


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10.1177/1740774519840268

Adverse publicity of serious side effects to healthy volunteers has limited effect on willingness-to-participate in clinical trials



A Comparative Study of Longitudinal Toxicities of Cytotoxic Drugs, Molecularly Targeted Agents, Immunomodulatory Drugs, and Cancer Vaccines


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10.1186/s12905-019-0804-4

Female perspectives on male involvement in a human-papillomavirus-based cervical cancer-screening program in western Kenya


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10.1007/s11864-019-0607-8

Targeted Therapy and Immunotherapy for Melanoma in Japan


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10.3748/wjg.v25.i24.2977

Immunotherapy for hepatocellular carcinoma: Current and future


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10.1007/978-1-4939-8938-6_8

Alloanergization Method for Inducing Allospecific Hyporesponsiveness in PBMC Exposed to Allostimulation In Vitro in the Context of Costimulatory Molecule Blockade.



Real-World Outcomes of an Automated Physician Support System for Genome-Driven Oncology


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10.1093/annonc/mdz244.057

Participation of women in phase I oncology clinical trials


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10.1093/jpepsy/jsy083

Commentary: Methods and Designs for T1 Translation in Pediatric Psychology


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10.1007/s00262-019-02442-5

Tailoring early-phase clinical trial design to address multiple research objectives


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10.1177/0962280219831038

A latent variable model for improving inference in trials assessing the effect of dose on toxicity and composite efficacy endpoints



Spotlight on fevipiprant and its potential in the treatment of asthma: evidence to date



BCMA CAR T cells: the winding path to success.


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10.1093/neuonc/noy176

Disparities along the glioblastoma clinical trials landscape


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10.1097/MOH.0000000000000489

Novel tyrosine kinase inhibitors for patients with inadequate response in chronic myeloid leukemia



Winning the RACE: Expanding pediatric cancer drug approvals


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10.3389/fonc.2019.00396

Review of PD-1/PD-L1 Inhibitors in Metastatic dMMR/MSI-H Colorectal Cancer


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10.1038/s41390-019-0673-4

When is a potential new neuroprotective treatment ready for translation?


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10.1038/s41591-019-0380-z

Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study


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10.1200/JGO.19.00156

Audit of Cancer Clinical Trials in India


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10.1200/JCO.2019.37.15_SUPPL.1066

Efficacy and safety of anti-PD-1 antibody SHR-1210 combined with apatinib in patients with advanced triple-negative breast cancer.



Now We Are 40 – 10 More Years of MOGA


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10.21037/cco.2019.06.05

Challenges and insights of early oncology drug development in the Asia-Pacific region: introduction of phase I oncology clinical trial center and experience sharing for early clinical trials in Seoul National University Hospital, Korea.


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10.3389/fpsyg.2019.02027

Effects of Ego-Depletion and State Anxiety on Performance Changes in Dart-Throwing Tasks: A Latent Curve Model Approach Reporting Trial Data for Human Participants


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10.1007/978-4-431-55585-8_1

Early-Phase Cancer Clinical Trials


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10.3389/fonc.2019.00180

Radiopharmaceuticals for Relapsed or Refractory Ovarian Cancers


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10.3390/cells8080860

Clinical Development of PARP Inhibitors in Treating Metastatic Castration-Resistant Prostate Cancer


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10.1371/journal.pone.0222117

Associations between industry involvement and study characteristics at the time of trial registration in biomedical research


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10.1097/JU.0000000000000297

Emerging Immunotherapy Options for BCG-unresponsive Non-muscle-invasive Bladder Cancer.


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10.3390/proceedings2019040010

Epibrassinolide Promotes the Apoptotic Potential of Gemcitabine in Pancreatic Cancer Cells



Clinical outcomes and survival of patients with myeloma and lymphoma enrolled into phase I clinical trials


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10.1002/bimj.201800250

A multistate model for early decision-making in oncology.


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10.3760/CMA.J.ISSN.0412-4030.2019.08.001

0.03%他克莫司软膏长期间歇维持治疗儿童特应性皮炎的多中心随机对照临床研究


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10.1016/S0140-6736(18)31999-8

Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study



Dose individualization and variable selection by using the Bayesian lasso in early phase dose finding trials



PARP inhibitors for BRCA wild type ovarian cancer; gene alterations, homologous recombination deficiency and combination therapy.


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10.1016/j.pharmthera.2018.09.008

Targeting Programmed Cell Death ‐1 (PD‐1) and Ligand (PD‐L1): A new era in cancer active immunotherapy



Early Weight Loss in Behavioral Treatment Predicts Later Rate of Weight Loss and Response to Pharmacotherapy.


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10.1200/JCO.2019.37.15_SUPPL.11018

Precision oncology in sarcoma drug development: Impact of genomic matching on response, clinical benefit, and survival in sarcoma patients on phase 1 trials.


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10.1212/WNL.0000000000007257

Winners, losers, and controls


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10.1016/B978-0-444-64185-4.00009-5

Natural Bioactive Cyclic Peptides and Peptidomimetics


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10.1212/WNL.0000000000007269

Pooled analysis suggests benefit of catheter-based hematoma removal for intracerebral hemorrhage



miRDRN—miRNA disease regulatory network: a tool for exploring disease and tissue-specific microRNA regulatory networks


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10.1038/s41581-019-0112-0

The genetic changes of Wilms tumour


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10.1038/s41571-019-0263-8

New targeted agents for urothelial carcinoma


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10.1016/j.clml.2018.12.009

Phase II Trial of MEK Inhibitor Binimetinib (MEK162) in RAS‐mutant Acute Myeloid Leukemia


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10.1016/j.jtho.2019.03.020

Safety and Efficacy of Crizotinib in Patients With Advanced or Metastatic ROS1-Rearranged Lung Cancer (EUCROSS): A European Phase II Clinical Trial.


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10.1182/blood.2018882555

Efficacy of venetoclax in relapsed chronic lymphocytic leukemia is influenced by disease and response variables.


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10.1007/978-3-319-92216-4_18

Novel treatments for advanced cholangiocarcinoma


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