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Patient Derived sentence examples within anti tumor effect



Synergetic delivery of triptolide and Ce6 with light-activatable liposomes for efficient hepatocellular carcinoma therapy



Translational Strategies for Repotrectinib in Neuroblastoma.


Patient Derived sentence examples within induced pluripotent stem



Microglial exosomes: taking messaging to new spheres



Lung Organoids And Other Preclinical Models Of Pulmonary Fibrosis.


Patient Derived sentence examples within invasive growth accompanying



Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice



OTME-13. Integration of metabolic and transcriptional signatures of glioblastoma invasion reveals extracellular matrix reorganization and vasculature remodeling




Patient Derived sentence examples within Primary Patient Derived



Synthesis of a Novel Pyrano[2,3-C]pyrazole Enabling PKBβ/AKT2 Inhibitory and in Vitro Anti-Glioma Activity



Functional metabolic phenotyping of human pancreatic ductal adenocarcinoma


Patient Derived sentence examples within Cancer Patient Derived



Detection of Tumor-Specific PTPmu in Gynecological Cancer and Patient Derived Xenografts



Ultrastructural analysis of breast cancer patient-derived organoids


Patient Derived sentence examples within Atrxlos Patient Derived



ATRXLoss Increases Sensitivity to Proton Radiotherapy Compared to X-Ray Radiotherapy in Glioma Stem Cells via Secondary Necrosis.



ATRXLoss to impair glioma stem cell viability and self-renewal via proton radiotherapy induced necrosis.


Patient Derived sentence examples within Disease Patient Derived



Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease



Automated microfluidic cell culture of stem cell derived dopaminergic neurons


Patient Derived sentence examples within Different Patient Derived



HGG-24. PRECLINICAL EFFICACY OF THE BRAIN PENETRANT CYCLIN-DEPENDENT KINASE INHIBITOR ZOTIRACICLIB IN PEDIATRIC DIFFUSE MIDLINE GLIOMAS



Radiotherapy is Associated With Global Methylation Alterations in Patient Derived Glioblastoma Cell Lines.


Patient Derived sentence examples within Glioblastoma Patient Derived



13109 Phosphorylation state of Myristoylated Alanine-Rich C-Kinase Substrate Effector Domain mimetics determines its cytotoxicity in glioblastoma and macrophage model



20902 Elucidation of Cardioprotective Mechanisms via Human Models of Chemotherapy-Induced Cardiotoxicity


Patient Derived sentence examples within Human Patient Derived



IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts



Rodent Brain Tumor Models for Neuro-Oncology Research


Patient Derived sentence examples within patient derived xenograft



Abstract PS17-03: Recurrent activeESR1fusions render a diagnostic transcriptional signature in metastatic breast cancer



Detection of Tumor-Specific PTPmu in Gynecological Cancer and Patient Derived Xenografts


Patient Derived sentence examples within patient derived organoid



Pre-clinical modelling of rectal cancer to develop novel radiotherapy-based treatment strategies



The Diverse Applications of Pancreatic Ductal Adenocarcinoma Organoids


Patient Derived sentence examples within patient derived cell



Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243A>G mtDNA mutation



Microglial exosomes: taking messaging to new spheres


Patient Derived sentence examples within patient derived tumor



Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis



Synergetic delivery of triptolide and Ce6 with light-activatable liposomes for efficient hepatocellular carcinoma therapy


Patient Derived sentence examples within patient derived gbm



Selective induction of rapid cytotoxic effect in glioblastoma cells by oscillating magnetic fields



Activation of estrogen receptor beta signaling reduces stemness of glioma stem cells


Patient Derived sentence examples within patient derived human



O47: IKK-ALPHA AS A POTENTIAL NOVEL TARGET FOR TREATMENT OF COLORECTAL CANCER



Generation of functional human thymic cells from induced pluripotent stem cells.


Patient Derived sentence examples within patient derived fibroblast



A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis



Okur-Chung Neurodevelopmental Syndrome-linked CK2α mutations have reduced kinase activity


Patient Derived sentence examples within patient derived orthotopic



Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice



OTME-13. Integration of metabolic and transcriptional signatures of glioblastoma invasion reveals extracellular matrix reorganization and vasculature remodeling


Patient Derived sentence examples within patient derived primary



Arginine deprivation therapy induces apoptotic cell death in melanoma brain metastasis



Enhanced anti-cancer activity of andrographis with oligomeric proanthocyanidins through activation of metabolic and ferroptosis pathways in colorectal cancer


Patient Derived sentence examples within patient derived glioma



Radiotherapy is Associated With Global Methylation Alterations in Patient Derived Glioblastoma Cell Lines.



ATRXLoss Increases Sensitivity to Proton Radiotherapy Compared to X-Ray Radiotherapy in Glioma Stem Cells via Secondary Necrosis.


Patient Derived sentence examples within patient derived neuron



Enhanced detection of nucleotide repeat mRNA with hybridization chain reaction



Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease


Patient Derived sentence examples within patient derived tissue



One carbon metabolism in human lung cancer.



4 Taking account of tumour heterogeneity in systematic reviews


Patient Derived sentence examples within patient derived ipsc



Congenital X-linked Neutropenia with Myelodysplasia and Somatic Tetraploidy due to a Germline Mutation in SEPT6.



Establishment of a GFP::LMNB1 knockin cell line (CSUi002-A-1) from a dystonia patient-specific iPSC by CRISPR/Cas9 editing.


Patient Derived sentence examples within patient derived glioblastoma



Synthesis of a Novel Pyrano[2,3-C]pyrazole Enabling PKBβ/AKT2 Inhibitory and in Vitro Anti-Glioma Activity



IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts


Patient Derived sentence examples within patient derived model



Patient derived models of bladder cancer amplify tumor specific gene expression compared to surgical specimen while maintaining gene expression of molecular subtype and epithelial mesenchymal transition markers



Single EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer


Patient Derived sentence examples within patient derived hipsc



Reliable generation of glial enriched progenitors from human fibroblast-derived iPSCs



Reliable Generation of Glial Enriched Progenitors from Human Fibroblast-Derived iPSCs


Patient Derived sentence examples within patient derived culture



Impairing Proliferation of Glioblastoma Multiforme with CD44+ Selective Conjugated Polymer Nanoparticles



Impairing Proliferation of Glioblastoma Multiforme with CD44+ Selective Conjugated Polymer Nanoparticles


Patient Derived sentence examples within patient derived induced



Lung Organoids And Other Preclinical Models Of Pulmonary Fibrosis.



MAPRE2 mutations result in altered human cranial neural crest migration, underlying craniofacial malformations in CSC-KT syndrome.


Patient Derived sentence examples within patient derived cancer



The Small-Molecule Inhibitor MRIA9 Reveals Novel Insights into the Cell Cycle Roles of SIK2 in Ovarian Cancer Cells



Abstract 2973: Establishment of organoids and patient derived cancer cell lines from gastric cancer body fluids as preclinical models for personalized therapy


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10.1093/BJS/ZNAB117.047

O47: IKK-ALPHA AS A POTENTIAL NOVEL TARGET FOR TREATMENT OF COLORECTAL CANCER


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10.1158/1538-7445.SABCS20-PS17-03

Abstract PS17-03: Recurrent activeESR1fusions render a diagnostic transcriptional signature in metastatic breast cancer


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10.3390/cancers13040801

AKT3 Expression in Mesenchymal Colorectal Cancer Cells Drives Growth and Is Associated with Epithelial-Mesenchymal Transition


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10.1016/j.biomaterials.2021.121189

The safe and effective intraperitoneal chemotherapy with cathepsin B-specific doxorubicin prodrug nanoparticles in ovarian cancer with peritoneal carcinomatosis.


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10.3390/cancers13030581

BMI1-Inhibitor PTC596 in Combination with MCL1 Inhibitor S63845 or MEK Inhibitor Trametinib in the Treatment of Acute Leukemia



Pre-clinical modelling of rectal cancer to develop novel radiotherapy-based treatment strategies


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10.1186/s40478-021-01243-1

Defining tumor-associated vascular heterogeneity in pediatric high-grade and diffuse midline gliomas



Congenital X-linked Neutropenia with Myelodysplasia and Somatic Tetraploidy due to a Germline Mutation in SEPT6.


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10.21203/RS.3.RS-676413/V1

Antibody-Mediated Blockade for Galectin-3 Binding Protein in Tumor Secretome Abrogates PDAC Metastasis


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10.1158/1538-7445.SABCS20-PS5-24

Abstract PS5-24: Novel genomic variants and pathways associated with baseline serum thymidine kinase 1 levels in HR-positive HER2-negative MBC patients commencing palbociclib and letrozole


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10.1186/s12935-021-01991-z

Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis


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10.1038/s41598-021-85004-z

Protein network analyses of pulmonary endothelial cells in chronic thromboembolic pulmonary hypertension


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10.1016/s0090-8258(21)01171-9

Silencing ROR2 inhibits metastatic behavior of ovarian cancer cells


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10.21203/rs.3.rs-857731/v1

Methionine Aminopeptidase 2 as a Potential Target in Pancreatic Ductal Adenocarcinoma


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10.1101/2021.01.06.425640

Enhanced detection of nucleotide repeat mRNA with hybridization chain reaction


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10.1101/2021.05.03.442419

Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death


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10.1101/2021.07.01.450506

Gasdermin B over-expression arbitrates HER2-targeted therapy resistance by inducing protective autophagy


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10.1101/2021.02.10.430614

Patient derived models of bladder cancer amplify tumor specific gene expression compared to surgical specimen while maintaining gene expression of molecular subtype and epithelial mesenchymal transition markers


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10.1007/978-1-0716-1020-6_18

Ewing Sarcoma PDX Models.


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10.1101/2021.01.28.428602

Encephalitis patient derived monoclonal GABAA receptor antibodies cause catatonia and epileptic seizures


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10.1038/s41598-021-97928-7

Neuronal mitochondrial dysfunction in sporadic amyotrophic lateral sclerosis is developmentally regulated


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10.3390/cancers13153712

Mouse Models in Meningioma Research: A Systematic Review


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10.1016/j.jaci.2021.07.021

Generation of functional human thymic cells from induced pluripotent stem cells.


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10.1038/s42003-021-02562-8

Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma


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10.1101/2021.04.02.438239

Discovery of Latent Drivers from Double Mutations in Pan-Cancer Data Reveal their Clinical Impact


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10.1158/1538-7445.TME21-PO045

Abstract PO045: Impact of fibroblast mediated stromal protection on evolution of resistance to targeted therapies in NSCLC



The Establishment and Utilization of Patient Derived Xenograft Models of Central Nervous System Metastasis.


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10.1016/j.scr.2021.102458

Reliable generation of glial enriched progenitors from human fibroblast-derived iPSCs


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10.1158/1538-7445.AM2021-3025

Abstract 3025: PRMT5 inhibition reduces viability and stemness of pediatric high grade glioma


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10.3390/cancers13174393

Effective Oncoleaking Treatment of Pancreatic Cancer by Claudin-Targeted Suicide Gene Therapy with Clostridium perfringens Enterotoxin (CPE)


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10.1158/1538-7445.AM2021-2970

Abstract 2970: Lower PTIP expression in appendiceal cancer is linked to oxaliplatin based HIPEC therapy resistance in patient derived tumor organoids


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10.1101/2021.08.19.456939

MINK1 modulates 5FU resistance in OSCC through AKT/MDM2 mediated regulation of p53


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10.1101/2021.05.27.21257584

Ileal derived organoids from Crohns disease patients show unique transcriptomic and secretomic signatures


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10.33774/chemrxiv-2021-c7xz5-v2

Impairing Proliferation of Glioblastoma Multiforme with CD44+ Selective Conjugated Polymer Nanoparticles


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10.1016/j.ijrobp.2021.09.017

Radioresistance and transcriptional reprograming of invasive glioblastoma cells.


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10.3760/cma.j.cn.441530-20210705-00261

[Advances in basic and translational research in neuroendocrine neoplasms].


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10.37469/0507-3758-2021-67-4-463-473

Experimental models in the study of pathogenesis and the development of treatments for ovarian cancer (systematic review)


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10.1371/journal.pone.0252099

ALK is frequently phosphorylated in Merkel cell carcinoma and associates with longer survival



Activation of estrogen receptor beta signaling reduces stemness of glioma stem cells



Druggable genome and precision medicine in cancer: current challenges.



Osteosarcoma of the Breast in a Patient Derived Orthotopic Xenograft (PDOX) Mouse Model Is Arrested by both Cisplatinum and Eribulin


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10.1093/neuonc/noab195.061

Arginine deprivation therapy induces apoptotic cell death in melanoma brain metastasis



Patient Derived
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