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Selective Oropharyngeal Decontamination

Objective To determine the cost-effectiveness of selective digestive decontamination (SDD) as compared to selective oropharyngeal decontamination (SOD) in intensive care units (ICUs) with low levels of antimicrobial resistance.

Cost-effectiveness of selective digestive decontamination (SDD) versus selective oropharyngeal decontamination (SOD) in intensive care units with low levels of antimicrobial resistance: an individual patient data meta-analysis

Selective Oropharyngeal Decontamination

OBJECTIVES To quantify the effects of selective digestive tract decontamination (SDD) consisting of a mouth paste and gastro-enteral suspension, selective oropharyngeal decontamination with a mouth paste (SOD) and 1-2% chlorhexidine (CHX) mouthwash on eradication and acquisition of carriage of third generation cephalosporin-resistant Enterobacterales (3GCR-E) and carbapenem resistant Gram-negative bacteria (CR-GNB) in ICU patients.

The effects of topical antibiotics on eradication and acquisition of 3rd-generation cephalosporin and carbapenem resistant Gram-negative bacteria in ICU patients; a post-hoc analysis from a multicenter cluster-randomized trial.

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10.1136/bmjopen-2018-028876

Objective To determine the cost-effectiveness of selective digestive decontamination (SDD) as compared to selective oropharyngeal decontamination (SOD) in intensive care units (ICUs) with low levels of antimicrobial resistance.

Cost-effectiveness of selective digestive decontamination (SDD) versus selective oropharyngeal decontamination (SOD) in intensive care units with low levels of antimicrobial resistance: an individual patient data meta-analysis

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10.1016/j.cmi.2019.08.001

OBJECTIVES To quantify the effects of selective digestive tract decontamination (SDD) consisting of a mouth paste and gastro-enteral suspension, selective oropharyngeal decontamination with a mouth paste (SOD) and 1-2% chlorhexidine (CHX) mouthwash on eradication and acquisition of carriage of third generation cephalosporin-resistant Enterobacterales (3GCR-E) and carbapenem resistant Gram-negative bacteria (CR-GNB) in ICU patients.

The effects of topical antibiotics on eradication and acquisition of 3rd-generation cephalosporin and carbapenem resistant Gram-negative bacteria in ICU patients; a post-hoc analysis from a multicenter cluster-randomized trial.

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10.1093/jac/dky573

Multiple individual studies of selective digestive decontamination/selective oropharyngeal decontamination (SDD/SOD) among ICU patients appear to show potent infection prevention effects.

Is selective decontamination (SDD/SOD) safe in the ICU context?

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10.1093/jac/dkz300

BACKGROUND Selective digestive decontamination (SDD) and selective oropharyngeal decontamination (SOD) regimens appear protective against ICU-acquired overall bacteraemia.

Studies of selective digestive decontamination as a natural experiment to evaluate topical antibiotic prophylaxis and cephalosporin use as population-level risk factors for enterococcal bacteraemia among ICU patients.

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10.1371/journal.pone.0218372

78]), current sedation score (higher scores at increased risk), current selective oropharyngeal decontamination (HR 0.

Using flexible methods to determine risk factors for ventilator-associated pneumonia in the Netherlands

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Oropharyngeal Decontamination
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What is/are Oropharyngeal Decontamination?

Oropharyngeal Decontamination - Objective To determine the cost-effectiveness of selective digestive decontamination (SDD) as compared to selective oropharyngeal decontamination (SOD) in intensive care units (ICUs) with low levels of antimicrobial resistance. [1] OBJECTIVES To quantify the effects of selective digestive tract decontamination (SDD) consisting of a mouth paste and gastro-enteral suspension, selective oropharyngeal decontamination with a mouth paste (SOD) and 1-2% chlorhexidine (CHX) mouthwash on eradication and acquisition of carriage of third generation cephalosporin-resistant Enterobacterales (3GCR-E) and carbapenem resistant Gram-negative bacteria (CR-GNB) in ICU patients. [2] Multiple individual studies of selective digestive decontamination/selective oropharyngeal decontamination (SDD/SOD) among ICU patients appear to show potent infection prevention effects. [3] BACKGROUND Selective digestive decontamination (SDD) and selective oropharyngeal decontamination (SOD) regimens appear protective against ICU-acquired overall bacteraemia. [4] 78]), current sedation score (higher scores at increased risk), current selective oropharyngeal decontamination (HR 0. [5]

Selective Oropharyngeal Decontamination

Objective To determine the cost-effectiveness of selective digestive decontamination (SDD) as compared to selective oropharyngeal decontamination (SOD) in intensive care units (ICUs) with low levels of antimicrobial resistance. [1] OBJECTIVES To quantify the effects of selective digestive tract decontamination (SDD) consisting of a mouth paste and gastro-enteral suspension, selective oropharyngeal decontamination with a mouth paste (SOD) and 1-2% chlorhexidine (CHX) mouthwash on eradication and acquisition of carriage of third generation cephalosporin-resistant Enterobacterales (3GCR-E) and carbapenem resistant Gram-negative bacteria (CR-GNB) in ICU patients. [2] Multiple individual studies of selective digestive decontamination/selective oropharyngeal decontamination (SDD/SOD) among ICU patients appear to show potent infection prevention effects. [3] BACKGROUND Selective digestive decontamination (SDD) and selective oropharyngeal decontamination (SOD) regimens appear protective against ICU-acquired overall bacteraemia. [4] 78]), current sedation score (higher scores at increased risk), current selective oropharyngeal decontamination (HR 0. [5]