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Opioid Abuse sentence examples within postoperative pain control

postoperative pain control

With respect to the concerns regarding opioid abuse, muscle relaxants and non-gabapentinoid anticonvulsant drugs can be regarded as a safe option for postoperative pain control.

A Review of Studies on the Use of New Non-Gabapentinoid Anticonvulsants and Muscle Relaxants in the Control of Acute Postoperative Pain

postoperative pain control

ABSTRACT IMPACT: The importance of this study is to evaluate the responses following the exposure of opioid drugs in young adults to address the current opioid epidemics OBJECTIVES/GOALS: To compare the proportion of patients between 18 and 25 years of age, who develop an opioid abuse disorder following dental surgery, to those following other surgical procedures, when an opioid drug is used for acute postoperative pain control.

64180 The Proportion of Young Patients with Acute Surgical Pain and Development of Opiate Abuse Disorders

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Opioid Abuse sentence examples within Prescription Opioid Abuse

Prescription Opioid Abuse

Relapse is a major obstacle to curb the ongoing epidemic of prescription opioid abuse.

Incubation of Oxycodone Craving Following Adult-Onset and Adolescent-Onset Oxycodone Self-Administration in Male Rats

Prescription Opioid Abuse

This model could be useful for studying the neurobiological substrates specifically relevant to prescription opioid abuse.

Modeling features of addiction with an oral oxycodone self-administration paradigm

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Opioid Abuse sentence examples within Postoperative Opioid Abuse

Postoperative Opioid Abuse

The implications of this problem are especially important to consider, as postoperative opioid abuse can give rise to true addiction for surgical patients.

An Analgesic Regimen for Opioid Reduction in Elective Plastic Surgery: A Randomized Prospective Study

Postoperative Opioid Abuse

However, there is no consensus regarding postoperative pain control after ESS, and postoperative opioid abuse is a problem in many countries.

Preemptive analgesia for endoscopic sinus surgery: a retrospective study.

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Opioid Abuse sentence examples within opioid abuse disorder

opioid abuse disorder

ABSTRACT IMPACT: The importance of this study is to evaluate the responses following the exposure of opioid drugs in young adults to address the current opioid epidemics OBJECTIVES/GOALS: To compare the proportion of patients between 18 and 25 years of age, who develop an opioid abuse disorder following dental surgery, to those following other surgical procedures, when an opioid drug is used for acute postoperative pain control.

64180 The Proportion of Young Patients with Acute Surgical Pain and Development of Opiate Abuse Disorders

opioid abuse disorder

Discrepancies in medical care are well known to adversely affect patients with opioid abuse disorders (OUD), including management and outcomes of acute myocardial infarction (AMI) in patients with OUD.

Comparison of Hospitalization Trends and Outcomes in Acute Myocardial Infarction Patients with versus without Opioid Use Disorder.

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Opioid Abuse sentence examples within opioid abuse epidemic

opioid abuse epidemic

Pain is among the most widespread chronic health condition confronting society today and our inability to manage chronic pain contributes to the opioid abuse epidemic in America.

Can FDA-Approved Immunomodulatory Drugs be Repurposed/Repositioned to Alleviate Chronic Pain?

opioid abuse epidemic

the advantages of IT drug delivery may be relevant given the opioid abuse epidemic in the US, which has led to an excessive number of deaths (33,091 opioid-related overdose deaths in 2015).

ESRA19-0704 PRO

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Opioid Abuse sentence examples within opioid abuse risk

opioid abuse risk

Opioid abuse risk was determined and categorized using adaptations from the Opioid Risk Tool (ORT).

Exposure to Hurricane Sandy and Risk of Opioid Abuse

opioid abuse risk

, opioid abuse risk) were relatively less favorable.

A Preliminary Study of Provider Burden in the Treatment of Chronic Pain: Perspectives of Physicians and People with Chronic Pain.

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Opioid Abuse sentence examples within opioid abuse represent

opioid abuse represent

Opioid abuse represents a public health crisis that has significant associated morbidity and mortality.

A history of opioid abuse: Why buprenorphine is superior for the management of opioid use disorder and pain.

opioid abuse represent

Chronic neuropathic pain and prescription opioid abuse represent highly interconnected societal problems.

Peripheral nerve injury promotes morphine-seeking behavior in rats during extinction

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10.3390/ijms22126421

Opioid abuse has become a major public health crisis that affects millions of individuals across the globe.

Integrated Systems Analysis of Mixed Neuroglial Cultures Proteome Post Oxycodone Exposure

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10.4103/jrpp.JRPP_21_17

Objective: Opioid abuse is widespread throughout the world.

The Safety and Effectiveness of Pharmacotherapy for Opioid-Overdose Induced Aspiration Pneumonia in a Referral Poisoning Management University Hospital in Iran

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10.1016/j.jseint.2020.12.019

Furthermore, a majority agreed that opioids may lead to other substance abuse with 76% reporting the risk of harm to be great, and only 55% believing that opioid abuse may lead to overdose or death.

What do patients think about opioids? a survey of patient perceptions regarding pain control after shoulder surgery

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10.3171/2020.10.JNS203323

Opioids are the mainstay of treatment, but opioid abuse has led to an epidemic in the United States.

Anterior insula stimulation increases pain threshold in humans: a pilot study.

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10.1039/D1RA00760B

Opioid abuse is a significant public health problem.

Silver nanoparticle on zinc oxide array for label-free detection of opioids through surface-enhanced raman spectroscopy

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10.1254/fpj.20107

In US, the additional indication of opioids to chronic pain has led to prolongation and generalization of opioid use, which may contribute to "opioid crisis" in which opioid-related death strikingly increased due to opioid abuse and overdose-induced respiratory depression.

[Current status and issues in clinical use of opioids].

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10.1016/j.ajem.2021.06.065

INTRODUCTION Opioid abuse and overdose deaths have reached epidemic proportions in the last couple decades.

A practical review of buprenorphine utilization for the emergency physician in the era of decreased prescribing restrictions.

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10.14740/gr1400

The electronic medical record was queried for history of alcohol abuse, opioid abuse, polysubstance abuse, prescriptions for psychotropic or opioid medications and ASA classification.

The Role of Clinical Characteristics in Stratifying Sedation Risk: A Cohort Study

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10.1007/s11916-021-00963-2

In light of the ongoing opioid epidemic and increasing awareness of the potential for opioid abuse and addiction, clinicians are progressively turning to interventional therapies.

Interventional Therapies for Pain in Cancer Patients: a Narrative Review

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10.36076/ppj.2021.24.e231-e237

BACKGROUND Opioid abuse has been an increasing problem since the 1990s.

Factors Predicting Chronic Opioid Use after Orthopedic Surgical Procedures.

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10.1016/j.ntt.2021.107033

However, opioid abuse does not occur in isolation-pregnant individuals abusing opioids often have a significant history of adverse experiences in childhood, among other co-occurring factors.

Co-occurrence of preconception maternal childhood adversity and opioid use during pregnancy: Implications for offspring brain development.

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10.1080/10826084.2021.1912098

Opioid abuse risk was determined and categorized using adaptations from the Opioid Risk Tool (ORT).

Exposure to Hurricane Sandy and Risk of Opioid Abuse

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10.1016/j.pbb.2020.173077

Opioid abuse has devastating effects on patients, their families, and society.

Divergent profiles of fentanyl withdrawal and associated pain in mice and rats

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10.1016/j.bbrc.2021.04.053

This paper also emphasizes the interconnection between the severities of neuronal injury induced by ischemic stroke or opioid abuse to circadian system.

Increase of Cry 1 expression is a common phenomenon of the disturbed circadian clock in ischemic stroke and opioid addiction.

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10.1186/s12884-021-03954-8

Women with postoperative wound complications, third and fourth degree lacerations, cesarean hysterectomy, or a history of opioid abuse were excluded.

The impact of race on postpartum opioid prescribing practices: a retrospective cohort study

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10.22543/0796.241.1052

Additionally, the subsequent sensitivity analysis revealed that since 2015, when national attention started to divert to new health concerns (opioid abuse, for example), physical activity levels pulled back to 2009 levels.

Effects of States’ Laws on Youth Physical Activity Participation and Obesity Prevalence

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10.1007/s43440-021-00251-1

A global problem connected with opioid abuse also requires the search for effective pharmacotherapy for opioid addiction, which is another potential application of biased compounds.

Influence of G protein-biased agonists of μ-opioid receptor on addiction-related behaviors

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10.1016/j.drugalcdep.2021.108886

METHODS We used an observational cohort study design to analyze insurance claims data from 2011 to 2016 from persons aged 12-64 with an opioid abuse or opioid dependence diagnosis and OUD treatment claim.

An examination between treatment type and treatment retention in persons with opioid and co-occurring alcohol use disorders.

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10.1021/acschembio.1c00026

Collectively, these findings provide new insights into the development of immunotherapeutic strategies aimed at opioid abuse and overdose.

A Highly Efficacious Carfentanil Vaccine That Blunts Opioid-Induced Antinociception and Respiratory Depression.

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10.1007/s11481-021-09993-4

These findings reinforce previous research showing that opioid abuse is associated with dysbiosis, therefore, warranting additional future research to elucidate the complex interaction between the host and opioid abuse during HIV and SIV infection.

Chronic Opioid Administration is Associated with Prevotella-dominated Dysbiosis in SIVmac251 Infected, cART-treated Macaques.

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10.1523/ENEURO.0547-20.2021

About half the people infected with human immunodeficiency virus (HIV) have neurocognitive deficits that often include memory impairment and hippocampal deficits, which can be exacerbated by opioid abuse.

HIV-1 Tat and Morphine Differentially Disrupt Pyramidal Cell Structure and Function and Spatial Learning in Hippocampal Area CA1: Continuous versus Interrupted Morphine Exposure

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10.1093/pm/pnab256

Low medical evidence was associated with increased burden, as mediated through lower pain credibility and greater concerns about patient depression, opioid abuse, and learning pain management.

Community Perspectives on Patient Credibility and Provider Burden in the Treatment of Chronic Pain.

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10.1016/j.jpain.2021.04.009

, opioid abuse risk) were relatively less favorable.

A Preliminary Study of Provider Burden in the Treatment of Chronic Pain: Perspectives of Physicians and People with Chronic Pain.

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10.1016/J.ARRES.2021.100003

Conclusions Opioids remain useful in both acute and chronic pain management but should be used cautiously and at specific times aided by tools assessing patient's risk of opioid abuse and pain chronicity.

Towards a Comprehensive Theory of Non-Cancer Acute and Chronic Pain Management: The Critical Role of Reactive Oxygen and Nitrogen Species in Pain, and Opioid Dependence, Addiction, Hyperalgesia, and Tolerance

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10.5055/jom.2021.0641

Opioid abuse represents a public health crisis that has significant associated morbidity and mortality.

A history of opioid abuse: Why buprenorphine is superior for the management of opioid use disorder and pain.

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10.1016/j.bjane.2021.05.002

BACKGROUND Anesthetic and/or opioid abuse is more prevalent among anesthesiologists than in other medical specialties and it has been associated with high mortality.

Postmortem qualitative analysis of psychological, occupational and environmental factors associated with lethal anesthetic and/or opioid abuse among anesthesiologists: case series.

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10.1016/j.ntt.2021.107002

Such knowledge is fundamental for the design of safer pharmacological interventions for opioid abuse, minimizing deleterious effects in the developing nervous system.

Endogenous and exogenous opioid effects on oligodendrocyte biology and developmental brain myelination.

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10.1016/j.pbb.2020.173072

Opioid abuse and related overdose deaths continue to rise in the United States contributing to the national opioid crisis in the USA.

Progress in opioid reward research: From a canonical two-neuron hypothesis to two neural circuits

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10.5055/jom.2021.0629

BACKGROUND Currently, in the United States, there is an epidemic of opioid abuse.

Engaging the opioid epidemic head on: Improving proper disposal of unused opioid medications after surgery.

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10.3389/fphar.2021.729220

The increase in the use of kratom in the United States has coincided with the serious epidemic of opioid abuse and dependence.

Kratom Use Within the Context of the Evolving Opioid Crisis and the COVID-19 Pandemic in the United States

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10.1016/j.japh.2021.01.025

Individuals at the highest risk for abusing gabapentin include those with opioid abuse, mental illness, or previous history of prescription drug abuse.

Gabapentin controlled substance status.

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10.1007/s00540-020-02887-4

Given its long half-life and high oral bioavailability, methadone has had a primary role in the outpatient treatment of patients with a history of opioid abuse or addiction.

Methadone: applications in pediatric anesthesiology and critical care medicine

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10.1016/j.drugalcdep.2021.108658

BACKGROUND Opioid abuse poses significant risk to individuals in the United States and epigenetic changes are a leading potential biomarker of opioid abuse.

Epigenome-wide study of brain DNA methylation following acute opioid intoxication.

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10.1007/s11481-021-10000-z

Pain is among the most widespread chronic health condition confronting society today and our inability to manage chronic pain contributes to the opioid abuse epidemic in America.

Can FDA-Approved Immunomodulatory Drugs be Repurposed/Repositioned to Alleviate Chronic Pain?

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10.1001/jama.2021.15255

Main Outcomes and Measures Outcomes studied were all-cause mortality, cardiovascular events, fractures, constipation, delirium, falls, opioid abuse/dependence, and sleep disorders within 1 year after the first dispensation.

Association of Tramadol vs Codeine Prescription Dispensation With Mortality and Other Adverse Clinical Outcomes.

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10.1016/j.eclinm.2021.100889

MRF cohorts were separated into three categories: substance abuse (alcohol, tobacco/nicotine, opioid abuse); vascular disease (hypertension, dyslipidemia); and dietary factors (malnutrition, obesity).

The influence of modifiable risk factors on short-term postoperative outcomes following cervical spine surgery: A retrospective propensity score matched analysis

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10.1093/neuros/nyab061

Overprescribing may adversely contribute to opioid abuse, chronic use, and diversion.

Reducing Superfluous Opioid Prescribing Practices After Brain Surgery: It Is Time to Talk About Drugs.

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10.3390/ijerph18010341

Opioid abuse and misuse have led to an epidemic which is currently spreading worldwide.

Health(care) in the Crisis: Reflections in Science and Society on Opioid Addiction

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10.1016/j.amjcard.2020.12.077

Discrepancies in medical care are well known to adversely affect patients with opioid abuse disorders (OUD), including management and outcomes of acute myocardial infarction (AMI) in patients with OUD.

Comparison of Hospitalization Trends and Outcomes in Acute Myocardial Infarction Patients with versus without Opioid Use Disorder.

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10.1017/S1041610220001660

This new behavioral epidemic of loneliness has led to an unprecedented reduction in longevity and contributes to the markedly increasing rates of “deaths of despair,” such as those due to suicides and opioid abuse ( Jeste et al.

Wisdom as a potential antidote to loneliness in aging

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10.1097/j.pain.0000000000002423

In contrast, long-term opioid therapy (≥ 6 months) in CNCP may not be superior to non-opioids in improving pain or disability/pain-related function, but seems to be associated with more AEs, opioid abuse/dependence, and possibly an increase in all-cause mortality.

Efficacy and safety of strong opioids for chronic non-cancer pain and chronic low back pain: a systematic review and meta-analyses.

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10.36076/ppj.2021.24.309

OBJECTIVES Explain the importance of screening for perceived injustice in patients with pain following cancer treatment, its potential relevance for opioid abuse, and its potential impact on the management of pain following cancer.

Pain and Opioid Use in Cancer Survivors: A Practical Guide to Account for Perceived Injustice.

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10.1080/10826084.2021.1926514

Objective: The objective of this qualitative study was to understand how clinicians perceived and used risk mitigation strategies for opioid abuse/misuse and identify barriers to implementation.

How Do Clinicians of Different Specialties Perceive and Use Opioid Risk Mitigation Strategies? A Qualitative Study

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10.1016/j.ebiom.2020.103192

Novel tools to better comprehend dynamic molecular changes in the brain associated with the opioid abuse are limited.

Brain cell-derived exosomes in plasma serve as neurodegeneration biomarkers in male cynomolgus monkeys self-administrating oxycodone.

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10.1093/sleep/zsab072.839

Conclusion: Discussion/Conclusion With a diagnosis of Severe Mixed Apnea Predominant OSA as well as CSA noted during the study, the differential diagnosis included CHF, Chiari malformation, opioid abuse and idiopathic CSA as the cause.

842 PAP Therapy in a Pandemic: Management of Severe Mixed Apnea Predominant OSA & CSA during the COVID-19 Pandemic

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10.1016/j.jval.2020.12.002

OBJECTIVES To assess the cost-effectiveness of an opioid abuse-prevention program embedded in the Narcotics Information Management System ("the Network System to Prevent Doctor-Shopping for Narcotics") in South Korea.

Cost-Effectiveness of an Opioid Abuse-Prevention Program Using the Narcotics Information Management System in South Korea.

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10.1093/RFS/HHAB066

We investigate the effects of opioid abuse on municipal finance.

Opioid Crisis Effects on Municipal Finance

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10.1016/j.neubiorev.2021.06.038

While there is evidence for many overlapping neural mechanisms underlying cocaine and opioid abuse, there is also a breadth of evidence indicating divergent effects of the drugs on synaptic plasticity.

Behavioral sex differences in cocaine and opioid use disorders: The role of gonadal hormones

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10.17992/lbl.2021.10.654

With this rise in use of opioids the risk of side effects, opioid abuse and deaths linked to opioids have become more apparent.

[Changes in prescriptions on opioids in primary health care during the years 2008-2017].

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10.1111/SSQU.12945

The correlation is strongest for the youngest users, holds for multiple classes of property crime, and its magnitude suggests hundreds of thousands of excess property crimes over the study period resulting from even modest increases in opioid abuse.

Prescription Opioid Misuse and Property Crime

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10.1016/j.japh.2020.12.022

The survey participants were asked to self-identify their interest in telephone interviews, which were analyzed using thematic coding to assess the role of the pharmacist in combating public health issues such as opioid abuse through interprofessional collaboration.

Gap analysis of pharmacist communication with community-based oral health care providers.

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10.1016/j.artd.2020.12.021

Background As America’s third highest opioid prescribers, orthopedic surgeons have contributed to the opioid abuse crisis.

Postdischarge Opioid Use after Total Hip and Total Knee Arthroplasty

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10.1177/08971900211004832

SUMMARY A 40 year-old-man with a prior history of opioid abuse who presented to the emergency department after taking up to 100 tablets of loperamide 2 mg daily for 5 years to blunt opioid withdrawal symptoms and was subsequently admitted to the intensive care unit for altered mental status and hyperthermia.

Loperamide Induced Recurrent Torsades de Pointes: A Case Report.

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10.1007/s00213-021-05962-0

These results further our understanding of the long-term costs and risk of opioid abuse, extending across generations.

Preconception paternal morphine exposure leads to an impulsive phenotype in male rat progeny.

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10.4103/mmj.mmj_402_19

Background An increasing phenomenon of opioid abuse has been demonstrated in Egypt in the last 4 years.

Visual-evoked potential changes in opioid addiction

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10.1016/j.ntt.2021.106964

Opioid abuse continues to plague society, and in recent years, there has been an epidemic, leading to increased addiction and death.

Zebrafish (Danio rerio) larvae show behavioral and embryonic development defects when exposed to opioids at embryo stage.

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10.3390/ENCYCLOPEDIA1010012

The inheritance of substance abuse, including opioid abuse, may be influenced by genetic and non-genetic factors related to the environment, such as stress and socioeconomic status.

Generational Effects of Opioid Exposure

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10.1177/0018578719882324

The overuse of opioids is due to the challenging nature of pain management, drug diversion prevention, and opioid abuse, as well as difficulty in recognizing and implementing best practices regarding opioid stewardship.

Before It Is Too Late: Implementation Strategies of an Efficient Opioid and Pain Stewardship Program

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10.5055/jom.2021.0609

The increase in opioid abuse could be attributed to the extended lockdowns and the social distancing recommendations, hindering chronic pain patients' access to regular office visits and monitoring in addition to limited access to behavioral services like group therapies and other pain management interventions.

Opioid epidemics during the pandemic: Further insights to the same story.

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10.1096/FASEBJ.2021.35.S1.04678

Recently, an inflammation associated chemokine receptor, CC Chemokine Receptor 5 (CCR5), has been linked to opioid abuse.

The CC Chemokine Receptor 5 (CCR5) antagonist Maraviroc inhibits drug‐choice in Sprague Dawley rats

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10.1016/j.drugalcdep.2021.108598

BACKGROUND Opioid abuse is a chronic disorder likely involving stable neuroplastic modifications.

Repeated morphine exposure activates synaptogenesis and other neuroplasticity-related gene networks in the dorsomedial prefrontal cortex of male and female rats.

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10.2174/1574884716666210129100455

The increasing prevalence of opioid abuse in developing countries may be a reason for the growing incidence of MI in younger ages and individuals with no risk factors.

Opioid dependency and myocardial infarction: A systematic review and meta-analysis.

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10.1113/JP281254

Furthermore, development of opioid addiction following analgesic use may contribute to an increasing incidence of opioid abuse, overdose, and death in North America.

Ketamine: yay or neigh? Implications for cardiovascular regulation and considerations for field use

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10.1016/j.amjoto.2021.103267

OBJECTIVE In otolaryngology, it is important to minimize the use of opioids for post-operative analgesia given the rise in opioid abuse and mortality due to overdose in the United States.

Adequate short- and long-term pain control with non-opiate analgesics after microdirect laryngoscopy.

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10.7759/cureus.16213

Methods: This is a retrospective analysis of electronic health records (EHR) of patients with diagnoses of opioid abuse.

Analysis of Factors Associated With Length of Stay of Opioid-Related Emergency Department Visits

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10.1016/j.cps.2020.09.003

Perioperative pain control is of increasing importance as awareness regarding the risks of under-controlled pain and opioid abuse rise.

Moving Toward Opioid-Free Breast Surgery: Regional Blocks and a Novel Technique.

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10.1017/CTS.2021.753

METHODS/STUDY POPULATION: A national sample of Veterans coded as having opioid abuse or dependence were previously categorized as (1) high likelihood of OUD, (2) limited aberrant opioid use, and (3) prescribed opioid use with no evidence of aberrant use based on chart review.

29120 Classification of Individuals Across the Spectrum of Problematic Opioid Use: Clinical Correlates and Longitudinal Associations with Mortality

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10.1016/j.ygeno.2021.03.006

Opioid abuse during pregnancy can result in Neonatal Opioid Withdrawal Syndrome (NOWS).

Placental DNA methylation profiles in opioid-exposed pregnancies and associations with the neonatal opioid withdrawal syndrome.

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10.1080/08897077.2021.1876199

The question of who enters into treatment for their opioid abuse and under what circumstances is complex and shaped by multiple factors.

Understanding barriers to treatment among individuals not engaged in treatment who misuse opioids: A structural equation modeling approach.

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10.3390/healthcare9050585

An evaluation model was established to analyze the severity of the opioid abuse based on the entropy weight method (EWM) and rank sum ratio (RSR).

Evaluation of Policy Effectiveness by Mathematical Modeling for the Opioid Crisis with Spatial Study and Trend Analysis

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10.1080/1059924X.2021.1893882

The other health behaviors services (sun/UV exposure, physical activity, mental health, tobacco cessation, alcohol/substance abuse, and opioid abuse) fell in-between.

Health Behavior Resources Available to Farmers in Rural Ohio.

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10.5430/jha.v10n4p26

Results: During the four-year period, the percent of patients diagnosed with infective endocarditis and a diagnosis code associated with opioid abuse or dependence doubled (4.

Hospitalized patients co-diagnosed with infective endocarditis and opioid drug dependence in Florida, 2015-2018

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10.1016/j.bbr.2020.112953

Opioid abuse is a major health problem.

Use of home cage wheel running to assess the behavioural effects of administering a mu/delta opioid receptor heterodimer antagonist for spontaneous morphine withdrawal in the rat

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10.1002/psp4.12687

Methadone is a synthetic opioid used as an analgesic and for the treatment of opioid abuse disorder.

Pharmacokinetic modeling of R and S‐Methadone and their metabolites to study the effects of various covariates in post‐operative children

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10.1093/SLEEP/ZSAB072.349

79] and opioid abusers (OR 11.

350 Opioid Use and Abuse are Associated with Use of Sedative Hypnotic Medications

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10.2139/ssrn.3135264

is experiencing an epidemic of opioid abuse.

The Effects of Naloxone Access Laws on Opioid Abuse, Mortality, and Crime

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10.1080/17425255.2021.1944099

Anecdotal reports concerning the beneficial effects of ibogaine for the treatment of opioid abuse and other drug dependencies appeared starting in the early 1960s [2], while the World Health Assembly classified ibogaine as a ‘substance likely to cause dependency or endanger human health’ and the Food and Drug Administration (FDA) assigned ibogaine to Schedule I classification.

Evaluating the toxicity and therapeutic potential of ibogaine in the treatment of chronic opioid abuse

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10.5055/jom.2021.0607

OBJECTIVES Recently, opioid abuse and related overdoses have increased warranting the need for research directed against the opioid epidemic.

Zinc deficiency: A cause of opioid-induced physical dependence and addiction in post-operative total hip arthroplasty patients.

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10.1007/s11739-021-02633-y

, age, liver disease, and opioid abuse), on symptoms compatible with COVID-19 (fever, dyspnea, either fever, or dyspnea; binary dependent variable).

COVID-19 and related symptoms in patients under disulfiram for alcohol use disorder

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10.1111/maq.12629

Opioid abuse is an increasingly global phenomenon.

Can a Neighborhood Fall Sick? Opioid Addiction, Collective Violence and Currents of Death in Contemporary India.

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10.1016/j.urology.2021.09.023

METHODS The Healthcare Cost and Utilization Project's (HCUP) inpatient, ambulatory, and emergency department databases from four states were queried to identify associations with a primary diagnosis code related to kidney stones followed by a diagnosis of opioid abuse, dependence, or overdose between 2005 and 2015.

Stones and Moans: Higher number of nephrolithiasis related encounters increases the odds of opioid misuse.

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10.1016/j.jsxm.2021.08.009

BACKGROUND While there is an increasing burden of chronic postoperative opioid use and opioid abuse in the United States, opioid use following inflatable penile prosthesis (IPP) surgery has not been well described.

Factors Impacting Postoperative Opioid Use Among Patients Undergoing Implantation of Inflatable Penile Prosthesis.

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10.1152/jn.00017.2021

, the rate of death from opioid abuse since the early 1990's has grown disproportionally, prompting the classification as a nationwide "epidemic".

Neuronal Mechanisms Underlying Opioid Induced Respiratory Depression: Our Current Understanding.

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10.1016/j.jpurol.2021.07.006

INTRODUCTION Opioid abuse is a public health crisis, and often this starts postoperatively.

Postoperative pediatric urology opioid prescriptions at a tertiary academic medical center.

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10.1007/s40278-021-04462-9

The patient, who had a history of opioid abuse on buprenorphine/naloxone [Suboxone], received the first dose of COVID-19 vaccination with Tozinameran [BNT162b2 mRNA vaccine; dose received and route not stated] on 18 April 2021.

Tozinameran

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10.2106/JBJS.20.00573

BACKGROUND After spinal surgery and other orthopaedic procedures, most patients receive opioids for pain, leading to potential complications such as pseudarthrosis and opioid abuse associated with long-term use.

Effect of Postoperative Analgesic Exposure to the Cannabinoid Receptor Agonist WIN55 on Osteogenic Differentiation and Spinal Fusion in Rats.

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Keywords related to Opioid

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Opioid Abuse
Encyclopedia

What is/are Opioid Abuse?

Opioid Abuse - Opioid abuse has become a major public health crisis that affects millions of individuals across the globe. [1] Objective: Opioid abuse is widespread throughout the world. [2] Furthermore, a majority agreed that opioids may lead to other substance abuse with 76% reporting the risk of harm to be great, and only 55% believing that opioid abuse may lead to overdose or death. [3] Opioids are the mainstay of treatment, but opioid abuse has led to an epidemic in the United States. [4] Opioid abuse is a significant public health problem. [5] In US, the additional indication of opioids to chronic pain has led to prolongation and generalization of opioid use, which may contribute to "opioid crisis" in which opioid-related death strikingly increased due to opioid abuse and overdose-induced respiratory depression. [6] INTRODUCTION Opioid abuse and overdose deaths have reached epidemic proportions in the last couple decades. [7] The electronic medical record was queried for history of alcohol abuse, opioid abuse, polysubstance abuse, prescriptions for psychotropic or opioid medications and ASA classification. [8] In light of the ongoing opioid epidemic and increasing awareness of the potential for opioid abuse and addiction, clinicians are progressively turning to interventional therapies. [9] BACKGROUND Opioid abuse has been an increasing problem since the 1990s. [10] However, opioid abuse does not occur in isolation-pregnant individuals abusing opioids often have a significant history of adverse experiences in childhood, among other co-occurring factors. [11] Opioid abuse risk was determined and categorized using adaptations from the Opioid Risk Tool (ORT). [12] Opioid abuse has devastating effects on patients, their families, and society. [13] This paper also emphasizes the interconnection between the severities of neuronal injury induced by ischemic stroke or opioid abuse to circadian system. [14] Women with postoperative wound complications, third and fourth degree lacerations, cesarean hysterectomy, or a history of opioid abuse were excluded. [15] Additionally, the subsequent sensitivity analysis revealed that since 2015, when national attention started to divert to new health concerns (opioid abuse, for example), physical activity levels pulled back to 2009 levels. [16] A global problem connected with opioid abuse also requires the search for effective pharmacotherapy for opioid addiction, which is another potential application of biased compounds. [17] METHODS We used an observational cohort study design to analyze insurance claims data from 2011 to 2016 from persons aged 12-64 with an opioid abuse or opioid dependence diagnosis and OUD treatment claim. [18] Collectively, these findings provide new insights into the development of immunotherapeutic strategies aimed at opioid abuse and overdose. [19] These findings reinforce previous research showing that opioid abuse is associated with dysbiosis, therefore, warranting additional future research to elucidate the complex interaction between the host and opioid abuse during HIV and SIV infection. [20] About half the people infected with human immunodeficiency virus (HIV) have neurocognitive deficits that often include memory impairment and hippocampal deficits, which can be exacerbated by opioid abuse. [21] Low medical evidence was associated with increased burden, as mediated through lower pain credibility and greater concerns about patient depression, opioid abuse, and learning pain management. [22] , opioid abuse risk) were relatively less favorable. [23] Conclusions Opioids remain useful in both acute and chronic pain management but should be used cautiously and at specific times aided by tools assessing patient's risk of opioid abuse and pain chronicity. [24] Opioid abuse represents a public health crisis that has significant associated morbidity and mortality. [25] BACKGROUND Anesthetic and/or opioid abuse is more prevalent among anesthesiologists than in other medical specialties and it has been associated with high mortality. [26] Such knowledge is fundamental for the design of safer pharmacological interventions for opioid abuse, minimizing deleterious effects in the developing nervous system. [27] Opioid abuse and related overdose deaths continue to rise in the United States contributing to the national opioid crisis in the USA. [28] BACKGROUND Currently, in the United States, there is an epidemic of opioid abuse. [29] The increase in the use of kratom in the United States has coincided with the serious epidemic of opioid abuse and dependence. [30] Individuals at the highest risk for abusing gabapentin include those with opioid abuse, mental illness, or previous history of prescription drug abuse. [31] Given its long half-life and high oral bioavailability, methadone has had a primary role in the outpatient treatment of patients with a history of opioid abuse or addiction. [32] BACKGROUND Opioid abuse poses significant risk to individuals in the United States and epigenetic changes are a leading potential biomarker of opioid abuse. [33] Pain is among the most widespread chronic health condition confronting society today and our inability to manage chronic pain contributes to the opioid abuse epidemic in America. [34] Main Outcomes and Measures Outcomes studied were all-cause mortality, cardiovascular events, fractures, constipation, delirium, falls, opioid abuse/dependence, and sleep disorders within 1 year after the first dispensation. [35] MRF cohorts were separated into three categories: substance abuse (alcohol, tobacco/nicotine, opioid abuse); vascular disease (hypertension, dyslipidemia); and dietary factors (malnutrition, obesity). [36] Overprescribing may adversely contribute to opioid abuse, chronic use, and diversion. [37] Opioid abuse and misuse have led to an epidemic which is currently spreading worldwide. [38] Discrepancies in medical care are well known to adversely affect patients with opioid abuse disorders (OUD), including management and outcomes of acute myocardial infarction (AMI) in patients with OUD. [39] This new behavioral epidemic of loneliness has led to an unprecedented reduction in longevity and contributes to the markedly increasing rates of “deaths of despair,” such as those due to suicides and opioid abuse ( Jeste et al. [40] In contrast, long-term opioid therapy (≥ 6 months) in CNCP may not be superior to non-opioids in improving pain or disability/pain-related function, but seems to be associated with more AEs, opioid abuse/dependence, and possibly an increase in all-cause mortality. [41] OBJECTIVES Explain the importance of screening for perceived injustice in patients with pain following cancer treatment, its potential relevance for opioid abuse, and its potential impact on the management of pain following cancer. [42] Objective: The objective of this qualitative study was to understand how clinicians perceived and used risk mitigation strategies for opioid abuse/misuse and identify barriers to implementation. [43] Novel tools to better comprehend dynamic molecular changes in the brain associated with the opioid abuse are limited. [44] Conclusion: Discussion/Conclusion With a diagnosis of Severe Mixed Apnea Predominant OSA as well as CSA noted during the study, the differential diagnosis included CHF, Chiari malformation, opioid abuse and idiopathic CSA as the cause. [45] OBJECTIVES To assess the cost-effectiveness of an opioid abuse-prevention program embedded in the Narcotics Information Management System ("the Network System to Prevent Doctor-Shopping for Narcotics") in South Korea. [46] We investigate the effects of opioid abuse on municipal finance. [47] While there is evidence for many overlapping neural mechanisms underlying cocaine and opioid abuse, there is also a breadth of evidence indicating divergent effects of the drugs on synaptic plasticity. [48] With this rise in use of opioids the risk of side effects, opioid abuse and deaths linked to opioids have become more apparent. [49] The correlation is strongest for the youngest users, holds for multiple classes of property crime, and its magnitude suggests hundreds of thousands of excess property crimes over the study period resulting from even modest increases in opioid abuse. [50]

postoperative pain control

With respect to the concerns regarding opioid abuse, muscle relaxants and non-gabapentinoid anticonvulsant drugs can be regarded as a safe option for postoperative pain control. [1] ABSTRACT IMPACT: The importance of this study is to evaluate the responses following the exposure of opioid drugs in young adults to address the current opioid epidemics OBJECTIVES/GOALS: To compare the proportion of patients between 18 and 25 years of age, who develop an opioid abuse disorder following dental surgery, to those following other surgical procedures, when an opioid drug is used for acute postoperative pain control. [2] However, there is no consensus regarding postoperative pain control after ESS, and postoperative opioid abuse is a problem in many countries. [3]

Prescription Opioid Abuse

Relapse is a major obstacle to curb the ongoing epidemic of prescription opioid abuse. [1] This model could be useful for studying the neurobiological substrates specifically relevant to prescription opioid abuse. [2] Prescription opioid abuse is one of the key sources of this issue. [3] BACKGROUND Limited studies have investigated the medication profile of young adult dental patients despite the high prevalence of prescription opioid abuse in this population. [4] Chronic neuropathic pain and prescription opioid abuse represent highly interconnected societal problems. [5] To characterize how prescription opioid abuse develops, this study investigated the affective consequences of escalating prescription opioid use using intracranial self‐stimulation (ICSS) reward and oxycodone intravenous self‐administration (IVSA) models. [6] The economic burden of prescription opioid abuse is also substantial, with approximately $78. [7]

Postoperative Opioid Abuse

The implications of this problem are especially important to consider, as postoperative opioid abuse can give rise to true addiction for surgical patients. [1] However, there is no consensus regarding postoperative pain control after ESS, and postoperative opioid abuse is a problem in many countries. [2]

opioid abuse disorder

ABSTRACT IMPACT: The importance of this study is to evaluate the responses following the exposure of opioid drugs in young adults to address the current opioid epidemics OBJECTIVES/GOALS: To compare the proportion of patients between 18 and 25 years of age, who develop an opioid abuse disorder following dental surgery, to those following other surgical procedures, when an opioid drug is used for acute postoperative pain control. [1] Discrepancies in medical care are well known to adversely affect patients with opioid abuse disorders (OUD), including management and outcomes of acute myocardial infarction (AMI) in patients with OUD. [2] Methadone is a synthetic opioid used as an analgesic and for the treatment of opioid abuse disorder. [3] Independent predictors of readmission were having Medicaid insurance, a Charlson comorbidity index score ≥ 3, use of total parenteral nutrition, opioid abuse disorder, prior pancreatic cyst, chronic alcoholic pancreatitis, and other chronic pancreatitis. [4] Due to its high oral bioavailablity and long duration of clinical effect, methadone is used (along with buprenorphine) for medication-assisted treatment of opioid abuse disorder (oral methadone maintenance replacing intravenous diamorphine [heroin]). [5]

opioid abuse epidemic

Pain is among the most widespread chronic health condition confronting society today and our inability to manage chronic pain contributes to the opioid abuse epidemic in America. [1] the advantages of IT drug delivery may be relevant given the opioid abuse epidemic in the US, which has led to an excessive number of deaths (33,091 opioid-related overdose deaths in 2015). [2] In the era of opioid abuse epidemics, there is an increased demand for understanding how opioid receptors can be allosterically modulated to guide the development of more effective and safer opioid therapies. [3]

opioid abuse risk

Opioid abuse risk was determined and categorized using adaptations from the Opioid Risk Tool (ORT). [1] , opioid abuse risk) were relatively less favorable. [2]

opioid abuse represent

Opioid abuse represents a public health crisis that has significant associated morbidity and mortality. [1] Chronic neuropathic pain and prescription opioid abuse represent highly interconnected societal problems. [2]