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Observational Database sentence examples within Large Observational Database
Design: Cross-design synthesis: risk prediction model developed and validated in large observational database, treatment effect estimates from risk-based reanalysis of clinical trial data.
Design: Cross-design synthesis: risk prediction model developed and validated in large observational database, treatment effect estimates from risk-based reanalysis of clinical trial data.
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Instead, they argue that greater emphasis should be placed on large observational databases, which can be analysed using powerful algorithms to determine which treatments work and for whom.
Instead, they argue that greater emphasis should be placed on large observational databases, which can be analysed using powerful algorithms to determine which treatments work and for whom.
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Observational Database sentence examples within Hiv Observational Database
FUNDING
The CHU St Pierre Brussels HIV Cohort, The Austrian HIV Cohort Study, The Australian HIV Observational Database, The AIDS Therapy Evaluation in the Netherlands national observational HIV cohort, The EuroSIDA cohort, The Frankfurt HIV Cohort Study, The Georgian National AIDS Health Information System, The Nice HIV Cohort, The ICONA Foundation, The Modena HIV Cohort, The PISCIS Cohort Study, The Swiss HIV Cohort Study, The Swedish InfCare HIV Cohort, The Royal Free HIV Cohort Study, The San Raffaele Scientific Institute, The University Hospital Bonn HIV Cohort and The University of Cologne HIV Cohorts, ViiV Healthcare, and Gilead Sciences.
FUNDING
The CHU St Pierre Brussels HIV Cohort, The Austrian HIV Cohort Study, The Australian HIV Observational Database, The AIDS Therapy Evaluation in the Netherlands national observational HIV cohort, The EuroSIDA cohort, The Frankfurt HIV Cohort Study, The Georgian National AIDS Health Information System, The Nice HIV Cohort, The ICONA Foundation, The Modena HIV Cohort, The PISCIS Cohort Study, The Swiss HIV Cohort Study, The Swedish InfCare HIV Cohort, The Royal Free HIV Cohort Study, The San Raffaele Scientific Institute, The University Hospital Bonn HIV Cohort and The University of Cologne HIV Cohorts, ViiV Healthcare, and Gilead Sciences.
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Methods Our decision analytic microsimulation model randomly selected (with replacement) individuals from the TREAT Asia HIV Observational Database (data collected between 1/January/2013 and 1/September/2019).
Methods Our decision analytic microsimulation model randomly selected (with replacement) individuals from the TREAT Asia HIV Observational Database (data collected between 1/January/2013 and 1/September/2019).
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Observational Database sentence examples within Prospective Observational Database
METHODS
Five hundred and one patients, including 300 males and 201 females (mean age 58 + 39 years) were identified retrospectively from a prospective observational database at a Level I Trauma Center.
METHODS
Five hundred and one patients, including 300 males and 201 females (mean age 58 + 39 years) were identified retrospectively from a prospective observational database at a Level I Trauma Center.
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A single-center retrospective analysis from a prospective observational database assessing the incidence of acute kidney injury in children undergoing extracorporeal membrane oxygenation, the use of continuous renal replacement therapy and its association with outcomes was performed.
A single-center retrospective analysis from a prospective observational database assessing the incidence of acute kidney injury in children undergoing extracorporeal membrane oxygenation, the use of continuous renal replacement therapy and its association with outcomes was performed.
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Observational Database sentence examples within Existing Observational Database
The existing observational database of the regional-scale distribution of strong ground motions and measured building response for major earthquakes continues to be quite sparse.
The existing observational database of the regional-scale distribution of strong ground motions and measured building response for major earthquakes continues to be quite sparse.
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The existing observational database of near-field ground motion records is in fact too limited to constitute a comprehensive basis for full understanding of the potential range of structural response variability at different locations near a major fault.
The existing observational database of near-field ground motion records is in fact too limited to constitute a comprehensive basis for full understanding of the potential range of structural response variability at different locations near a major fault.
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Observational Database sentence examples within Designed Observational Database
METHODS
We analyzed 712 treatment-naive eyes (ANZ - 474; Switzerland - 321) starting anti-VEGF for nAMD in routine clinical practice between January 1, 2006 and December 31, 2008 tracked in the prospectively designed observational database - the Fight Retinal Blindness! Registry.
METHODS
We analyzed 712 treatment-naive eyes (ANZ - 474; Switzerland - 321) starting anti-VEGF for nAMD in routine clinical practice between January 1, 2006 and December 31, 2008 tracked in the prospectively designed observational database - the Fight Retinal Blindness! Registry.
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Observational Database sentence examples within Global Observational Database
By comparing the BrO/SO2 molar ratios collected from 13 eruptive phases to volcanic activity, this study aims to broaden the global observational database investigating their link.
By comparing the BrO/SO2 molar ratios collected from 13 eruptive phases to volcanic activity, this study aims to broaden the global observational database investigating their link.
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Estimates of global oceanic CCl4 uptake are derived from a range of model analyses, including prescribed parameterizations using reported values on hydrolysis and degradation, and analyses optimized using the global observational databases.
Estimates of global oceanic CCl4 uptake are derived from a range of model analyses, including prescribed parameterizations using reported values on hydrolysis and degradation, and analyses optimized using the global observational databases.
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Observational Database sentence examples within Retrospective Observational Database
METHODS
Retrospective observational database including all patients attending a cardiological preoperative assessment from the 1st of January 2016 to the 31st of December 2019.
METHODS
Retrospective observational database including all patients attending a cardiological preoperative assessment from the 1st of January 2016 to the 31st of December 2019.
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METHODS
A retrospective observational database study was conducted, reviewing the medical charts of 69 adult survivors with a history of a vascular ring, identified from the Dutch Congenital Cor vitia database.
METHODS
A retrospective observational database study was conducted, reviewing the medical charts of 69 adult survivors with a history of a vascular ring, identified from the Dutch Congenital Cor vitia database.
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Observational Database sentence examples within Within Observational Database
There is an opportunity to identify drug event patterns within observational databases for evaluating ontogenic-mediated adverse event mechanisms.
There is an opportunity to identify drug event patterns within observational databases for evaluating ontogenic-mediated adverse event mechanisms.
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There is an opportunity to design data mining methodologies to identify and evaluate drug event patterns within observational databases for ontogenic-mediated adverse event mechanisms.
There is an opportunity to design data mining methodologies to identify and evaluate drug event patterns within observational databases for ontogenic-mediated adverse event mechanisms.
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Observational Database sentence examples within U Observational Database
Observational Database sentence examples within observational database study
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10.1093/EUROPACE/EUAB116.151
METHODS
Retrospective observational database including all patients attending a cardiological preoperative assessment from the 1st of January 2016 to the 31st of December 2019.
METHODS
Retrospective observational database including all patients attending a cardiological preoperative assessment from the 1st of January 2016 to the 31st of December 2019.
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10.5194/egusphere-egu21-8225
The observational database includes altimetric and gravimetric satellite data as well as Argo floats.
The observational database includes altimetric and gravimetric satellite data as well as Argo floats.
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10.1093/pasj/psab024
We may have identified a candidate star in the observational database where elemental abundances and kinematic data are available.
We may have identified a candidate star in the observational database where elemental abundances and kinematic data are available.
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10.5194/EGUSPHERE-EGU21-6082
</p><p>The behaviour shown by the centennial reanalyses are likely caused by the increasing number of assimilated observations, changes in the observational databases used, and the different underlying numerical model systems.
</p><p>The behaviour shown by the centennial reanalyses are likely caused by the increasing number of assimilated observations, changes in the observational databases used, and the different underlying numerical model systems.
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10.1186/s13040-021-00264-9
There is an opportunity to identify drug event patterns within observational databases for evaluating ontogenic-mediated adverse event mechanisms.
There is an opportunity to identify drug event patterns within observational databases for evaluating ontogenic-mediated adverse event mechanisms.
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10.1109/TLA.2021.9443060
This work presents a methodology based on Markov chains for the generation of a global irradiance time series with one-minute temporal resolution using observational database acquired by a basic weather station.
This work presents a methodology based on Markov chains for the generation of a global irradiance time series with one-minute temporal resolution using observational database acquired by a basic weather station.
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10.1016/J.RESPE.2021.04.043
When randomized experiments are not feasible or available, causal effects are often estimated from observational databases.
When randomized experiments are not feasible or available, causal effects are often estimated from observational databases.
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10.1136/annrheumdis-2020-219765
Both studies used observational databases to examine the relationship between VKA use and OA and both found a positive association, one by examining acenocoumarol use and risk of incident and progressive knee and hip OA and the other examining warfarin use and risk of knee or hip replacement.
Both studies used observational databases to examine the relationship between VKA use and OA and both found a positive association, one by examining acenocoumarol use and risk of incident and progressive knee and hip OA and the other examining warfarin use and risk of knee or hip replacement.
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10.1101/2021.01.06.21249334
Design: Cross-design synthesis: risk prediction model developed and validated in large observational database, treatment effect estimates from risk-based reanalysis of clinical trial data.
Design: Cross-design synthesis: risk prediction model developed and validated in large observational database, treatment effect estimates from risk-based reanalysis of clinical trial data.
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10.1016/j.afjem.2020.09.016
Methods A retrospective analysis was performed on a prospectively collected observational database.
Methods A retrospective analysis was performed on a prospectively collected observational database.
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10.1101/2021.03.10.21253302
There is an opportunity to design data mining methodologies to identify and evaluate drug event patterns within observational databases for ontogenic-mediated adverse event mechanisms.
There is an opportunity to design data mining methodologies to identify and evaluate drug event patterns within observational databases for ontogenic-mediated adverse event mechanisms.
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10.1038/s41409-021-01435-2
However, when used to analyze observational databases with large sample sizes or highly stratified treatment groups such as in registry-related datasets, these programmes are inefficient or unable to generate confidence bands and simultaneous p values.
However, when used to analyze observational databases with large sample sizes or highly stratified treatment groups such as in registry-related datasets, these programmes are inefficient or unable to generate confidence bands and simultaneous p values.
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10.1186/s12894-021-00881-w
Methods This was a retrospective, descriptive, observational database study using UK Clinical Practice Research Datalink GOLD and linked databases.
Methods This was a retrospective, descriptive, observational database study using UK Clinical Practice Research Datalink GOLD and linked databases.
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10.1016/S2352-3018(21)00163-6
FUNDING
The CHU St Pierre Brussels HIV Cohort, The Austrian HIV Cohort Study, The Australian HIV Observational Database, The AIDS Therapy Evaluation in the Netherlands national observational HIV cohort, The EuroSIDA cohort, The Frankfurt HIV Cohort Study, The Georgian National AIDS Health Information System, The Nice HIV Cohort, The ICONA Foundation, The Modena HIV Cohort, The PISCIS Cohort Study, The Swiss HIV Cohort Study, The Swedish InfCare HIV Cohort, The Royal Free HIV Cohort Study, The San Raffaele Scientific Institute, The University Hospital Bonn HIV Cohort and The University of Cologne HIV Cohorts, ViiV Healthcare, and Gilead Sciences.
FUNDING
The CHU St Pierre Brussels HIV Cohort, The Austrian HIV Cohort Study, The Australian HIV Observational Database, The AIDS Therapy Evaluation in the Netherlands national observational HIV cohort, The EuroSIDA cohort, The Frankfurt HIV Cohort Study, The Georgian National AIDS Health Information System, The Nice HIV Cohort, The ICONA Foundation, The Modena HIV Cohort, The PISCIS Cohort Study, The Swiss HIV Cohort Study, The Swedish InfCare HIV Cohort, The Royal Free HIV Cohort Study, The San Raffaele Scientific Institute, The University Hospital Bonn HIV Cohort and The University of Cologne HIV Cohorts, ViiV Healthcare, and Gilead Sciences.
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10.5194/EGUSPHERE-EGU21-3894
By comparing to the observational database, these indicators allow us to better constrain the model ensemble, and demonstrate that the models with more efficient surface to deep transport are best aligned with current observations.
By comparing to the observational database, these indicators allow us to better constrain the model ensemble, and demonstrate that the models with more efficient surface to deep transport are best aligned with current observations.
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10.1016/J.EUJIM.2021.101342
Methods This observational database study was reported according to the RECORD guideline.
Methods This observational database study was reported according to the RECORD guideline.
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10.3960/jslrt.20056
The CLIMBER-DBR (Treatment practices and patient burden in chronic lymphocytic leukemia and mantle cell lymphoma patients in the real world: An observational database research in Japan) study examined the clinical characteristics, treatment patterns, and healthcare resource utilization of MCL in a real-world clinical setting in Japan.
The CLIMBER-DBR (Treatment practices and patient burden in chronic lymphocytic leukemia and mantle cell lymphoma patients in the real world: An observational database research in Japan) study examined the clinical characteristics, treatment patterns, and healthcare resource utilization of MCL in a real-world clinical setting in Japan.
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10.1038/s41467-021-21485-w
Using privacy preserving probabilistic linkage, we link these 975 records with two observational databases providing data on HIV events (Zurich Primary HIV Infection study and the Swiss HIV Cohort Study).
Using privacy preserving probabilistic linkage, we link these 975 records with two observational databases providing data on HIV events (Zurich Primary HIV Infection study and the Swiss HIV Cohort Study).
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10.1186/s12911-021-01543-5
Background In Japan, a multiple-hospital observational database system, the Medical Information Database Network (MID-NET®), was launched for post-marketing drug safety assessments.
Background In Japan, a multiple-hospital observational database system, the Medical Information Database Network (MID-NET®), was launched for post-marketing drug safety assessments.
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10.1371/journal.pone.0256926
Methods Our decision analytic microsimulation model randomly selected (with replacement) individuals from the TREAT Asia HIV Observational Database (data collected between 1/January/2013 and 1/September/2019).
Methods Our decision analytic microsimulation model randomly selected (with replacement) individuals from the TREAT Asia HIV Observational Database (data collected between 1/January/2013 and 1/September/2019).
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10.1002/eap.2356
In this analysis, we combined a literature review and effect-size meta-analysis with two large, independent, observational databases to assess how land use and management impact SOC stocks, primarily with regards to forest land uses.
In this analysis, we combined a literature review and effect-size meta-analysis with two large, independent, observational databases to assess how land use and management impact SOC stocks, primarily with regards to forest land uses.
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10.1097/EDE.0000000000001338
To illustrate the application of the autoencoder-based PS, we emulated the PRONOUNCE trial by applying the trial’s protocol elements within an observational database setting, comparing two chemotherapy regimens.
To illustrate the application of the autoencoder-based PS, we emulated the PRONOUNCE trial by applying the trial’s protocol elements within an observational database setting, comparing two chemotherapy regimens.
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10.1016/j.jbi.2021.103849
METHODS
We propose a two-stage workflow for solving an existing gap in Extraction, Transformation and Loading (ETL) procedures regarding observational databases.
METHODS
We propose a two-stage workflow for solving an existing gap in Extraction, Transformation and Loading (ETL) procedures regarding observational databases.
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10.1177/8755293020970980
The existing observational database of the regional-scale distribution of strong ground motions and measured building response for major earthquakes continues to be quite sparse.
The existing observational database of the regional-scale distribution of strong ground motions and measured building response for major earthquakes continues to be quite sparse.
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10.21203/RS.3.RS-257772/V1
Methods: This was a retrospective, descriptive, observational database study using UK Clinical Practice Research Datalink GOLD and linked databases.
Methods: This was a retrospective, descriptive, observational database study using UK Clinical Practice Research Datalink GOLD and linked databases.
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10.21203/RS.3.RS-227607/V1
Methods: We used five US observational databases to develop patient-level prediction models.
Methods: We used five US observational databases to develop patient-level prediction models.
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10.1016/j.jclinepi.2021.08.028
Observational databases are often used to study causal questions.
Observational databases are often used to study causal questions.
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10.1177/2047487320925639
This retrospective, observational database study examined the joint effect of obesity and cardiovascular risk status on HCRU and compared HCRU between body mass index (BMI) categories and CVD-risk categories in the UK.
This retrospective, observational database study examined the joint effect of obesity and cardiovascular risk status on HCRU and compared HCRU between body mass index (BMI) categories and CVD-risk categories in the UK.
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10.1080/03007995.2021.1913109
Objective This study aimed to determine rates of hospitalization and in-hospital mortality in the first year following amyloidosis diagnosis with cardiac involvement using observational databases.
Objective This study aimed to determine rates of hospitalization and in-hospital mortality in the first year following amyloidosis diagnosis with cardiac involvement using observational databases.
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10.1186/s12874-021-01370-2
We used five US observational databases to develop patient-level prediction models.
We used five US observational databases to develop patient-level prediction models.
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10.1080/09540121.2021.1884181
Using data from the Australian HIV Observational Database, we compared clinical characteristics of those with heterosexually-acquired (Het-HIV) to homosexually-acquired HIV (Hom-HIV) to investigate any differences and their implications for clinical management.
Using data from the Australian HIV Observational Database, we compared clinical characteristics of those with heterosexually-acquired (Het-HIV) to homosexually-acquired HIV (Hom-HIV) to investigate any differences and their implications for clinical management.
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10.28974/idojaras.2019.2.6
11° nominal resolutions) against the CARPATCLIM high resolution gridded observational database.
11° nominal resolutions) against the CARPATCLIM high resolution gridded observational database.
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10.1016/j.thromres.2018.12.010
RESULTS
Totally, 189,483 patients from 11 RCTs and 3 observational database studies were included in the analysis (119,188 patients with NOACs and 70,295 patients with vitamin K Antagonists or acetylsalicylic acid).
RESULTS
Totally, 189,483 patients from 11 RCTs and 3 observational database studies were included in the analysis (119,188 patients with NOACs and 70,295 patients with vitamin K Antagonists or acetylsalicylic acid).
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10.1093/humrep/dez199
Instead, they argue that greater emphasis should be placed on large observational databases, which can be analysed using powerful algorithms to determine which treatments work and for whom.
Instead, they argue that greater emphasis should be placed on large observational databases, which can be analysed using powerful algorithms to determine which treatments work and for whom.
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10.1016/j.wneu.2019.05.195
METHODS
Five hundred and one patients, including 300 males and 201 females (mean age 58 + 39 years) were identified retrospectively from a prospective observational database at a Level I Trauma Center.
METHODS
Five hundred and one patients, including 300 males and 201 females (mean age 58 + 39 years) were identified retrospectively from a prospective observational database at a Level I Trauma Center.
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10.1016/j.therap.2019.01.007
Studies based on observational databases are particularly useful for psychotropic drugs due to their important prevalence in populations, and their use over long period.
Studies based on observational databases are particularly useful for psychotropic drugs due to their important prevalence in populations, and their use over long period.
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10.1002/hon.158_2631
Here, we describe the case report of pt with refractory ENKL successfully treated with haploidentical transplantation (haploSCT) and provide the analysis of ENKL in Caucasian pts using the observational database of the Czech Lymphoma Study Group (CLSG).
Here, we describe the case report of pt with refractory ENKL successfully treated with haploidentical transplantation (haploSCT) and provide the analysis of ENKL in Caucasian pts using the observational database of the Czech Lymphoma Study Group (CLSG).
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10.1093/ofid/ofz360.2165
Methods HIV+ adults, suppressed to <50 copies/mL at RALQD initiation (7/1/2017–December 31/2017), were identified in the OPERA® Observational Database, a collaboration following 100,000 people living with HIV through electronic medical records.
Methods HIV+ adults, suppressed to <50 copies/mL at RALQD initiation (7/1/2017–December 31/2017), were identified in the OPERA® Observational Database, a collaboration following 100,000 people living with HIV through electronic medical records.
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10.1093/ofid/ofz360.2166
Methods ART-naïve adults, initiating a DTG- or EVG-based regimen and meeting all study eligibility criteria (Figure 1) were identified in the OPERA® Observational Database, a collaboration of HIV caregivers following 100,000+ people living with HIV (PLWH) through electronic medical records.
Methods ART-naïve adults, initiating a DTG- or EVG-based regimen and meeting all study eligibility criteria (Figure 1) were identified in the OPERA® Observational Database, a collaboration of HIV caregivers following 100,000+ people living with HIV (PLWH) through electronic medical records.
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10.1016/j.chest.2018.09.014
METHODS: CT scans and pulmonary function test results were acquired from an observational database for N = 12 patients with COPD and N = 12 control patients.
METHODS: CT scans and pulmonary function test results were acquired from an observational database for N = 12 patients with COPD and N = 12 control patients.
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10.1007/s11192-019-03291-w
Using abstracts presented from 2013 to 2016 at an annual meeting (International Workshop on HIV/Hepatitis Observational Databases), we determined how many were subsequently published in peer-reviewed journals.
Using abstracts presented from 2013 to 2016 at an annual meeting (International Workshop on HIV/Hepatitis Observational Databases), we determined how many were subsequently published in peer-reviewed journals.
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10.1093/jamia/ocz113
DISCUSSION
Race and ethnicity data are critical to support precision medicine initiatives and to determine healthcare disparities; however, the quality of this information in observational databases is concerning.
DISCUSSION
Race and ethnicity data are critical to support precision medicine initiatives and to determine healthcare disparities; however, the quality of this information in observational databases is concerning.
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10.1002/pst.1908
Networks of constellations of longitudinal observational databases, often electronic medical records or transactional insurance claims or both, are increasingly being used for studying the effects of medicinal products in real-world use.
Networks of constellations of longitudinal observational databases, often electronic medical records or transactional insurance claims or both, are increasingly being used for studying the effects of medicinal products in real-world use.
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10.1177/0391398819876294
A single-center retrospective analysis from a prospective observational database assessing the incidence of acute kidney injury in children undergoing extracorporeal membrane oxygenation, the use of continuous renal replacement therapy and its association with outcomes was performed.
A single-center retrospective analysis from a prospective observational database assessing the incidence of acute kidney injury in children undergoing extracorporeal membrane oxygenation, the use of continuous renal replacement therapy and its association with outcomes was performed.
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10.12783/shm2019/32124
The existing observational database of near-field ground motion records is in fact too limited to constitute a comprehensive basis for full understanding of the potential range of structural response variability at different locations near a major fault.
The existing observational database of near-field ground motion records is in fact too limited to constitute a comprehensive basis for full understanding of the potential range of structural response variability at different locations near a major fault.
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10.1097/IAE.0000000000002485
PURPOSE
To evaluate the accuracy of an observational database that tracks real-world treatment outcomes for neovascular age-related macular degeneration.
PURPOSE
To evaluate the accuracy of an observational database that tracks real-world treatment outcomes for neovascular age-related macular degeneration.
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10.1016/J.JAG.2019.05.023
The field observational database from the Spanish Ministry of Agriculture, Fisheries and Food was used for validation purposes.
The field observational database from the Spanish Ministry of Agriculture, Fisheries and Food was used for validation purposes.
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10.1080/14397595.2019.1660028
Such observational databases, which reflect the reality of daily clinical practice, will become increasingly important and may provide a model for similar research in other disease areas.
Such observational databases, which reflect the reality of daily clinical practice, will become increasingly important and may provide a model for similar research in other disease areas.
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10.1016/j.ajo.2019.03.001
DESIGN
Retrospective analysis from a prospectively designed observational database.
DESIGN
Retrospective analysis from a prospectively designed observational database.
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10.1158/1538-7445.SABCS18-P4-14-05
Confirmation of the TAILORx 21-gene expression trial using a real world observational database [abstract].
Confirmation of the TAILORx 21-gene expression trial using a real world observational database [abstract].
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10.1007/s00345-019-02648-3
Methods The study consists on an observational database designed with the view to analyse the incidence and characteristics of HAIs in Urology.
Methods The study consists on an observational database designed with the view to analyse the incidence and characteristics of HAIs in Urology.
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10.15562/bmj.v8i1.977
Methods: The population was HIV-infected children who were registered in 2006-2014 Sanglah hospital’s TApHOd (Treat Asia Pediatric HIV Observational Database) cohort.
Methods: The population was HIV-infected children who were registered in 2006-2014 Sanglah hospital’s TApHOd (Treat Asia Pediatric HIV Observational Database) cohort.
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10.1080/23744235.2018.1544423
ARCA (antiviral response cohort analysis) is a public observational database created for surveillance of HIV drug resistance and for the implementation of models predictive of virological response to antiviral treatment.
ARCA (antiviral response cohort analysis) is a public observational database created for surveillance of HIV drug resistance and for the implementation of models predictive of virological response to antiviral treatment.
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10.5194/ACP-19-4615-2019
A total of 40 thermally driven downslope events are selected from an observational database spanning the summer 2017 period by using an objective and systematic algorithm that accounts for a weak synoptic forcing and local downslope wind direction.
A total of 40 thermally driven downslope events are selected from an observational database spanning the summer 2017 period by using an objective and systematic algorithm that accounts for a weak synoptic forcing and local downslope wind direction.
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10.5194/ACP-19-2497-2019
These comparisons aimed to provide a
comprehensive overview of typical uncertainties in the observational database
that could be considered in the future in observational and modelling studies.
These comparisons aimed to provide a
comprehensive overview of typical uncertainties in the observational database
that could be considered in the future in observational and modelling studies.
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10.1017/S0033291719003295
We identified multiple factors that fuel the controversy: certainty of evidence is low to moderate; modest efficacy on top of strong placebo effects allows critics to focus on small net efficacy and advocates on large gross efficacy; ADM withdrawal symptoms masquerade as relapse/recurrence; lack of association between ADM treatment and long-term outcome in observational databases.
We identified multiple factors that fuel the controversy: certainty of evidence is low to moderate; modest efficacy on top of strong placebo effects allows critics to focus on small net efficacy and advocates on large gross efficacy; ADM withdrawal symptoms masquerade as relapse/recurrence; lack of association between ADM treatment and long-term outcome in observational databases.
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10.1029/2018GB006110
The model can reproduce both these observational databases; however, substantial dissolution of aragonite above the aragonite saturation horizon is required to do so.
The model can reproduce both these observational databases; however, substantial dissolution of aragonite above the aragonite saturation horizon is required to do so.
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10.1038/s41467-019-11597-9
Here we map global SOC turnover times (τ) in the subsoil layer at 1 km resolution using observational databases.
Here we map global SOC turnover times (τ) in the subsoil layer at 1 km resolution using observational databases.
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10.1007/978-3-030-41032-2_33
The same subset, but based on observational database E-OBS, is taken from the open archive ClimData and used as reference.
The same subset, but based on observational database E-OBS, is taken from the open archive ClimData and used as reference.
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10.3851/IMP3298
METHODS
Analyses were based on patients recruited to the TREAT Asia HIV Observational Database (TAHOD), consisting of 21 sites in 12 countries.
METHODS
Analyses were based on patients recruited to the TREAT Asia HIV Observational Database (TAHOD), consisting of 21 sites in 12 countries.
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10.1080/13696998.2019.1643354
Methods: This retrospective, observational database study analyzed claims data from the Truven MarketScan databases.
Methods: This retrospective, observational database study analyzed claims data from the Truven MarketScan databases.
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10.3389/feart.2019.00132
By comparing the BrO/SO2 molar ratios collected from 13 eruptive phases to volcanic activity, this study aims to broaden the global observational database investigating their link.
By comparing the BrO/SO2 molar ratios collected from 13 eruptive phases to volcanic activity, this study aims to broaden the global observational database investigating their link.
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10.1080/01621459.2020.1864382
Finally, we explore finite-sample properties via simulation, and apply the methods to an observational database used to assess the effects of right heart catheterization.
Finally, we explore finite-sample properties via simulation, and apply the methods to an observational database used to assess the effects of right heart catheterization.
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10.4103/jesnt.jesnt_16_19
Patients and methods A prospective, observational database was undertaken at a tertiary referral hematological and oncological center hospital.
Patients and methods A prospective, observational database was undertaken at a tertiary referral hematological and oncological center hospital.
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10.3390/atmos10100594
This analysis is motivated by the implementation of an atmospheric chemistry model with an advanced data assimilation system that will use the observational database over NEB with the model to overcome high uncertainties in the model results induced by still unvalidated emission inventories.
This analysis is motivated by the implementation of an atmospheric chemistry model with an advanced data assimilation system that will use the observational database over NEB with the model to overcome high uncertainties in the model results induced by still unvalidated emission inventories.
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10.1029/2018GL080612
Estimates of global oceanic CCl4 uptake are derived from a range of model analyses, including prescribed parameterizations using reported values on hydrolysis and degradation, and analyses optimized using the global observational databases.
Estimates of global oceanic CCl4 uptake are derived from a range of model analyses, including prescribed parameterizations using reported values on hydrolysis and degradation, and analyses optimized using the global observational databases.
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10.1136/bmjopen-2018-024928
Design Observational database study.
Design Observational database study.
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10.1055/a-0859-7561
METHODS
This was an analysis of a prospective observational database from the German Hepatitis C Registry (DHC-R) covering a period from May 2014 to September 2015.
METHODS
This was an analysis of a prospective observational database from the German Hepatitis C Registry (DHC-R) covering a period from May 2014 to September 2015.
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10.1016/j.ajo.2019.10.007
METHODS
We analyzed 712 treatment-naive eyes (ANZ - 474; Switzerland - 321) starting anti-VEGF for nAMD in routine clinical practice between January 1, 2006 and December 31, 2008 tracked in the prospectively designed observational database - the Fight Retinal Blindness! Registry.
METHODS
We analyzed 712 treatment-naive eyes (ANZ - 474; Switzerland - 321) starting anti-VEGF for nAMD in routine clinical practice between January 1, 2006 and December 31, 2008 tracked in the prospectively designed observational database - the Fight Retinal Blindness! Registry.
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10.2147/COPD.S214061
Methods This was a historical observational database study.
Methods This was a historical observational database study.
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10.1213/ANE.0000000000003829
For our first study, we established a multicenter observational database to characterize the analgesic strategies used to manage pediatric patients undergoing MIRPE.
For our first study, we established a multicenter observational database to characterize the analgesic strategies used to manage pediatric patients undergoing MIRPE.
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10.1089/neu.2018.6153
A prospective, observational database of severe TBI survivors from a single institution was analyzed.
A prospective, observational database of severe TBI survivors from a single institution was analyzed.
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10.1214/18-AOAS1207
For this, we analyze data from a cohort study on kidney disease and from a large observational database on neurodegenerative diseases.
For this, we analyze data from a cohort study on kidney disease and from a large observational database on neurodegenerative diseases.
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10.1111/dom.13509
FDA recently reviewed the article titled, "Comparative effectiveness of canagliflozin, SGLT2 inhibitors and non-SGLT2 inhibitors on the risk of hospitalization for heart failure and amputation in patients with type 2 diabetes mellitus: A real-world meta-analysis of 4 observational databases (OBSERVE-4D)1 ," and had the following comment back to Janssen: We acknowledge that we reviewed multiple revisions of the protocol for this voluntary study; however, we did not reach final agreement on the protocol prior to initiation of the study.
FDA recently reviewed the article titled, "Comparative effectiveness of canagliflozin, SGLT2 inhibitors and non-SGLT2 inhibitors on the risk of hospitalization for heart failure and amputation in patients with type 2 diabetes mellitus: A real-world meta-analysis of 4 observational databases (OBSERVE-4D)1 ," and had the following comment back to Janssen: We acknowledge that we reviewed multiple revisions of the protocol for this voluntary study; however, we did not reach final agreement on the protocol prior to initiation of the study.
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10.1007/s10198-019-01122-6
Conclusions Combining the strengths of randomised controlled trials and observational databases in cost-effectiveness models can generate policy-relevant results to allow well-informed decision-making.
Conclusions Combining the strengths of randomised controlled trials and observational databases in cost-effectiveness models can generate policy-relevant results to allow well-informed decision-making.
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10.1016/J.BRAT.2019.103412
The major challenges in this proposed approach are that treatment are not randomly assigned in observational databases and that these databases often lack measures of key prescriptive predictors and mental disorder treatment outcomes.
The major challenges in this proposed approach are that treatment are not randomly assigned in observational databases and that these databases often lack measures of key prescriptive predictors and mental disorder treatment outcomes.
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10.1161/JAHA.118.010198
We sought to explore the prognostic impact of AVA in asymptomatic patients with severe AS in a large observational database.
We sought to explore the prognostic impact of AVA in asymptomatic patients with severe AS in a large observational database.
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10.1016/j.jstrokecerebrovasdis.2019.06.041
However, given the potential for bias with observational databases, case reports and case series, extreme caution is warranted in applying these results to routine clinical practice.
However, given the potential for bias with observational databases, case reports and case series, extreme caution is warranted in applying these results to routine clinical practice.
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10.1097/iae.0000000000002679
METHODS
Retrospective analysis of data from a prospectively designed, multicenter, observational database.
METHODS
Retrospective analysis of data from a prospectively designed, multicenter, observational database.
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10.1016/j.scitotenv.2019.05.109
We describe the AIRTREE model framework, accuracy and sensitivity by comparing modeling results against long-term continuous Eddy Covariance measurements of ozone, water, and CO2 fluxes in a Mediterranean Holm oak forest, and we discuss potential application of AIRTREE for ozone-risk assessment in view of availability of a large observational database from ecosystems distributed worldwide.
We describe the AIRTREE model framework, accuracy and sensitivity by comparing modeling results against long-term continuous Eddy Covariance measurements of ozone, water, and CO2 fluxes in a Mediterranean Holm oak forest, and we discuss potential application of AIRTREE for ozone-risk assessment in view of availability of a large observational database from ecosystems distributed worldwide.
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