Introduction to Novel Focal

Author summary Our novel Focal Adhesion Filament Cross-correlation Kit (FAFCK) allows for fast, reliable, unbiased, and systematic detection of focal adhesions and actin stress fibers in cells and their mutual correlation.

Taken together, a novel focal adhesion related gene signature can be used for prognostic prediction in HCC, which may be a therapeutic alternative.

A novel focal plane is employed that is optimized to observe both the UV fluorescence signal from extensive air showers (EASs) and the optical Cherenkov signals from EASs.

We aimed to develop a novel focal stroke model using a microcatheter and zirconium dioxide that is non-magnetic under fluoroscopic guidance, which can monitor MCA occlusion and can improve hemorrhagic complications.

The tumor exhibited a novel focal micropapillary architecture, in addition to the previously described microscopic features.

In the present work we have developed a novel focal EAE model to further study the effect of innate signaling on demyelinating pathology.

We aimed to develop a novel focal stroke model using a cell-im.

Moreover, we propose a novel Focal Triplet Loss to make the model focus more on hard examples than the easy ones.

We aimed to develop a novel focal stroke model using a microcatheter and zirconium dioxide that is non-magnetic under fluoroscopic guidance, which can monitor MCA occlusion and can improve hemorrhagic complications.

To overcome this problem, we developed a novel focal EPT approach utilizing nanocomposite hydrogels composed of a poly(dl-lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(dl-lactide-co-glycolide) (PLGA-PEG-PLGA) copolymer, LAPONITE, and β-galactosidase (β-gal).

In addition, many novel focal patterns occurred with tunable intensity distribution.

Besides, novel focal amplifications/deletions involving ZBTB7B, SLC4A4, TBX18, CYSLTR2 and EFNA5 were frequently present in tumors.

present the development of a novel focal plane array for laser gated viewing at SWIR wavelengths.

This interesting paper describes a Phase-1 study on a novel focal treatment modality.

A novel focal plane design is optimized to observe the UV air fluorescence signal from extensive air showers (EASs) in a stereoscopic UHECR observation mode and the Cherenkov signals from EASs from UHECRs and neutrino-induced τ-leptons in an Earth-limb viewing mode.

In addition to, some novel focal intensity distributions appeared.

Objective To describe the clinical and histopathological characteristics of a novel focal epilepsy in Boerboel dogs.

2) transfer learning: we show how transfer learning along with intelligent pre-processing can result in better Alzheimer's diagnosis using a much smaller training set 3) data imbalance: we show how our novel focal Tversky loss function can provide better segmentation results taking into account the imbalanced nature of segmentation datasets.

To increase the robustness of the training and improve segmentation, we introduce a novel focal loss function.

The inhibitory effects of NCTD on invasiveness were compared with those of a novel focal adhesion kinase (FAK) kinase inhibitor, PF-562271.

A series of 7H-pyrrolo[2,3-d]pyrimidine derivatives possessing a dimethylphosphine oxide moiety were designed, synthesized and evaluated as novel Focal adhesion kinase (FAK) inhibitors.

Our results also suggest potential novel focal points for future therapeutic interventions in alcohol use disorder.

Here, we review novel focal prostate cancer treatments and their associated recent clinical data, with a particular focus on data reported within the last 24 months.

,This paper provides new and important insight into the nature of EI within a novel focal group.

Here, we identified β8 integrin in a high-throughput knockdown screen in three-dimensional (3D), ECM-based cell cultures for novel focal adhesion protein targets as a critical determinant of PDAC cell radiochemoresistance.

Many novel focal patterns including flattop profile, focal hole axially separated focal spots and focal spot with long focal depth are evolved considerably for the suitable beam parameters.

Objective This study aimed to develop a preclinical model of prostate cancer (CaP) for studying focal/hemiablation of the prostate (IDEAL stage 0), and to use the information from the stage 0 investigation to design a novel focal surgical treatment approach—the precision prostatectomy (IDEAL stage 1/2a).

A series of 2,7-disubstituted-thieno[3,2-d]pyrimidine derivatives were designed, synthesized and evaluated as novel focal adhesion kinase (FAK) inhibitors.

In addition, we propose a novel Focal-Hinge loss to alleviate the class imbalance of semantics in the training stage.