Introduction to Non Transfusion Dependent
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The management of several patients with non transfusion dependent thalassaemia (NTDT) committed to receive regular blood transfusions may be cumbersome because of the occurrence of severe post-transfusion reactions and/or the development of irregular antibodies.
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Hemoglobin E beta thalassemia (HbE β thalassemia), a compound heterozygous state, result in a very variable phenotype ranging from thalassemia trait, Non Transfusion dependent Thalassemia (NTDT), to Transfusion dependent Thalassemia (TDT).
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