Introduction to Non Neuronal Cholinergic
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Perturbations in non-neuronal cholinergic signaling mechanisms are associated with periodontitis; however, their role in generalized aggressive periodontitis (GAgP) is unknown.
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Whereas prior studies have demonstrated an important immunomodulatory role for the neuronal cholinergic system in the heart, the role of the non-neuronal cholinergic system is not well understood.
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In recent years a non-neuronal cholinergic system has been described in immune cells, which is often usually activated during the course of inflammatory processes.
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However, the study of the non-neuronal cholinergic system has focused on lymphocyte cholinergic mechanisms, with less attention to its role of innate cells.
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