Introduction to Non Inferiority Randomized

Methods The current study protocol outlines a plan to conduct the first non-inferiority randomized controlled trial aimed to explore the efficacy of BWRT compared to treatment as usual (TAU), operationalized as any evidence-based trauma treatment method administered in Norwegian out-patient clinics.

METHODS In this non-inferiority randomized controlled trial, 108 patients undergoing general anaesthesia were randomly allocated to receive either LPP or CP during LMA insertion.

Methods: We conducted a non-inferiority randomized controlled trial comparing between 30-minute pressure support ventilation (PSV) and 30-minute T-piece in ventilated patients with EFL who got ready to wean.

Methods: This paper outlines the protocol for a multi-center, three-arm, parallel, non-inferiority randomized controlled trial (RCT) of an evidence-based manualized psychological intervention, ACT-Adjust.

We present a study protocol for a prospective non-inferiority randomized clinical trial, comparing the efficacy and safety of CO 2 laser versus physiotherapy for treatment in women with SUI.

Recently non-inferiority randomized controlled trials by French [5] and Japanese group [6] have shown equivalent survival and long-term functional outcome in SLN biopsy and elective neck dissection (END) group.

The aim was to assess complication rates following transradial coronary procedures and to compare two radial compression devices in a non-inferiority randomized controlled trial.

We conducted this open-labeled non-inferiority randomized controlled trial in a tertiary level teaching hospital in India from May 2017 to March 2018.

Methods: A non-inferiority randomized controlled trial was adopted in this study.

Methods A multi-center, open label, non-inferiority randomized controlled trial has been designed to identify if SLN mapping alone is not inferior to pelvic lymphadenectomy on prognosis of patients with intermediate-high-risk EC clinically confined to uterus.

RESULTS The efficacy of hypofractionated radiotherapy, compared to conventional radiotherapy, regarding biochemical control, was evaluated in five superiority and four non-inferiority randomized phase III studies.

The goal of this non-inferiority randomized controlled trial (RCT) was to compare the short and long-term efficacy of a stepped care CBT-I (StepCBT-I) to a standard face-to-face CBT-I (StanCBT-I).

Non-inferiority randomized controlled trial (RCT) effectiveness may erode when results favour the active control over time, and when a decreasingly effective control arm is used in serial trials.

METHODS: We conducted a non-inferiority randomized controlled trial at the Mayo Clinic, Rochester, Minnesota.

Non-inferiority randomized controlled trial, having included adult patients with ax-SpA fulfilling ASAS criteria, already treated by anti-TNF, and in stable low disease activity for at least 6 m (current and at least 6 m old BASDAI<4/10), who were randomized into 2 groups: either keeping on their usual treatment with stable doses (“unchanged” group), or progressive spacing of injections of their treatment (“spacing” group).

It is not easy to research and publish ‘‘cheaper IR’’; for example, to reveal cheaper IR that has similar efficacy to existing standard treatments, a non-inferiority randomized controlled trial is needed [2], but this is extremely difficult in reality.

Trial design: Pilot multicenter non-inferiority randomized clinical trial.

Methods We conducted a parallel non-inferiority randomized control trial using a variable block randomization to a 10-min training session on either a toilet paper or commercial mannequin trainer.

We then present the findings of our non-inferiority randomized controlled trial of a pharmacist-led osteoporosis group clinic.

Method In a non-inferiority randomized controlled trial, unselected primary healthcare patients (≥ 18 years old) were given a brief introduction and asked to log on to the study website to fill in the 3-item version of the Alcohol Use Disorders Identification Test.

INTRODUCTION AND OBJECTIVES The Stents Coated With the Biodegradable Polymer on Their Abluminal Faces and Elution of Sirolimus Versus Biolimus Elution for the Treatment of de Novo Coronary Lesions - DESTINY Trial is a non-inferiority randomized study that compared the Inspiron™ sirolimus-eluting stent (SES) with the control Biomatrix™ Flex biolimus-eluting stent (BES).

METHODS Non-inferiority randomized, clinical trial involving patients presenting with acute respiratory failure conducted in the ED of a local hospital.

METHOD this is a non-inferiority randomized clinical trial, with two parallel arms.

Methods The REMICRUSH (Remifentanil for Rapid Sequence Induction of Anaesthesia) study is a multicenter, single-blinded, non-inferiority randomized controlled trial comparing remifentanil (3 to 4 μg/kg) with rapid-onset paralytic agents (succinylcholine or rocuronium 1 mg/kg) for rapid sequence induction in 1150 adult surgical patients requiring tracheal intubation during general anesthesia.

A non-inferiority randomized controlled design was used.

We present a study protocol for a prospective non-inferiority randomized clinical trial, comparing the efficacy and safety of CO2 laser versus physiotherapy for treatment in women with SUI.

Recently, lenvatinib showed similar results in terms of survival in a non-inferiority randomized trial study considering the same subset of patients.

METHODS  We designed a multi-centre, non-inferiority randomized trial comparing daily oral eltrombopag starting 3 weeks pre-operatively, and IVIG administered 1 week pre-operatively for patients with ITP requiring a platelet count increase prior to surgery.

METHODS A prospective, open-label, parallel, and non-inferiority randomized controlled trial was performed involving critically ill adults in 6 university hospitals in China between September 2017 and May 2019.

Cerebrovascular Drug-Eluting Stent versus Bare-Metal Stent in the Treatment of Vertebral Artery Stenosis: A Non-Inferiority Randomized Clinical Trial.

Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid: a pragmatic non-inferiority randomized controlled trial.

Methods/designThe EOF after total laparoscopic radical gastrectomy (SOFTLY) study is a single-center, parallel-arm, non-inferiority randomized controlled trial which will enroll 200 patients who are pathologically diagnosed with gastric cancer and undergo laparoscopic radical gastrectomy.

Dear Editor Our published manuscript, entitled “A multi-center, open-label, two-arm parallel group non-inferiority randomized controlled trial evaluating the effect of pitavastatin, compared to atorvastatin, on glucose metabolism in prediabetics with hypertension and dyslipidemia: rationale and design for the China hemoglobin A1c Metabolism Protection Union Study (CAMPUS),” has received a request from Mr.

METHODS: This was a non-inferiority randomized trial, comparing prostate-cancer detection rate between transperineal and transrectal MRI-US fusion targeted fusion biopsies.

DESIGN Non-inferiority randomized controlled trial.

Methods: In this multicenter open-label non-inferiority randomized controlled trial, patients fulfilling ACR-EULAR 2010 criteria for RA were included if they were 1) treated with ABA or TCZ for ≥ 1 year (monotherapy or in combination with csDMARD, corticosteroid allowed at a dose ≤ 5 mg/day), 2) in DAS28VS remission (DAS28 <2.

Trial design Multicentric Open labelled, non-inferiority randomized controlled phase III trial.

DesignRe-evaluation based on data from a multicenter non-inferiority randomized clinical trial (RCT).

Recently, lenvatinib showed similar results in terms of survival in a non-inferiority randomized trial study considering the same subset of patients.

of a non-inferiority randomized clinical trial on the waitand-see strategy performed in the Netherlands [3], present a series of reasons in support of the respective views, but the complexity and heterogeneity of factors involved in decision-making in this setting [4] support the need for further considerations to facilitate a balanced view of this notsimple clinical topic.

This phase III non-inferiority randomized clinical trial enrolled patients at 17 sites between September 2010 and May 2013.

Methods and findings This multicentre, non-inferiority randomized clinical trial randomly assigned 530 adult patients with CT-confirmed uncomplicated acute appendicitis to appendectomy or antibiotic treatment at six Finnish hospitals.

Methods and Results: The CIBIS-J trial is a multicenter, open-label, non-inferiority randomized controlled trial of bisoprolol vs.

Design Samples were obtained from an unblinded, non-inferiority randomized controlled trial where participants were recruited on a rolling basis for the first six months of the study, then followed-up for 12 months with samples collected at enrollment, quarterly, and during sick visits.

DESIGN A single centre prospective, open label, non-inferiority randomized controlled trial.

BACKGROUND In a double-blind, non-inferiority randomized controlled trial injectable hydromorphone, a licensed short acting opioid analgesic, was shown to be as effective as diacetylmorphine for the treatment of severe opioid use disorder.

The study was an open-label non-inferiority randomized controlled trial.

We conducted a blinded non-inferiority randomized controlled trial including infants aged less than 12 months old, hospitalized for a moderate bronchiolitis.