Introduction to Neonatal Septic

Conclusions: Antimicrobial surveillance of neonatal septicaemia is required to know the antibiotic sensitivity pattern and thus to formulate policies on use of antibiotics and to know the changing spectrum of antimicrobial sensitivity patterns.

BACKGROUND Neonatal septicaemia is a bacterial infection with positive blood culture in first four weeks of life.

The diagnosis of neonatal septicemia is occasionally complicated by unusual clinical presentations.

Background: Neonatal septicemia is a clinical syndrome characterized by signs and symptoms of infection with or without accompanying bacteremia in the first month of life.

The incidence of neonatal septicemia varies widely between the developed world anddeveloping countries.

Functional echocardiographic preload markers are evaluated in children and adults, but there is no data in neonatal septic shock.

Introduction: Neonatal septicaemia is one of the most common leading causes of neonatal morbidity and mortality in developing countries.

Objective: To investigate the predictive value of lactate concentration within 1 h after admission combined with lactate clearance rate (LC) at 6 h after fluid resuscitation in prognosis of neonatal septic shock.

The early diagnosis of neonatal septicemia still poses great difficulties.

Background Group B Streptococcus (GBS) was identified as the leading cause of neonatal septic factor and a major factor in female genital infections.

Background Neonatal septic shock is a significant cause of morbidity and mortality.

Antimicrobial prescription for neonatal septicaemia (NS) should be wisely used depending on the regional spectra of infecting microbes and their antimicrobial resistance (AMR) patterns which vary over time, place and host factors.

Our study describes how OXA-48-like carbapenemases in neonatal septicemic Klebsiella pneumoniae shows remarkable diversity in the genomes of the strains and relatedness with strains from other parts of world and also to some neonatal outbreak strains.

com Background: Accurate and rapid diagnosis of neonatal septicemia is highly warranted because of high associated morbidity and mortality.

Listeria monocytogenes is a cause of infectious food-borne disease in humans, characterized by neurological manifestations, abortion, and neonatal septicemia.

Most of the studies evaluating serum PCT as a diagnostic marker for neonatal septicemia have been carried out in peripheral venous blood with smaller sample sizes with inclusion of neonates without considering perinatal sepsis score.

cloacae outbreak of fulminant neonatal septic shock, we conducted a study to determine whether septic shock severity and its lethal consequence are related to structural features of the endotoxin (lipopolysaccharide [LPS]) of the strains isolated from hospitalized infants and more specifically its lipid A region.

This study investigates susceptibility toward three fluoroquinolones (ciprofloxacin, levofloxacin, moxifloxacin), multiple fluoroquinolone-resistance mechanisms, and epidemiological relationship of neonatal septicaemic Acinetobacter baumannii.

Primary diseases were severe asphyxia in 6 cases, neonatal septicemia in 5 cases, congenital hereditary metabolic disease in 2 cases, traumatic asphyxia in 1 case, and liver failure in 1 case.

Neonatal septicemia either acquired from the mother (vertical transmission) or nosocomial (horizontal transmission) is a forbidable problem encountered in the neonatal unit and is the commonest primary cause of morbidity and mortality among neonates.

Introduction: Neonatologists face a perpetual challenge in managing neonatal septicaemia due to changing patterns of the microbial flora and their antibiotic sensitivity.

OBJECTIVE To delineate the pattern of joint involvement in neonatal septic arthritis, assess the prognosis, and determine significant predictors of unfavorable outcome.

Background: Staphylococcus epidermidis has emerged as the pathogen from neonatal septicemia.

Background The term early onset neonatal septicaemia (EONS) refers to invasive bacterial infections that primarily involve the blood stream of neonates during the first 3 days of life.

Background The aim of this study was to evaluate the diagnostic value of C-reactive protein (CRP) test in detecting neonatal septicemia.

Background: Neonatal septicemia signifies a generalized bacterial infection documented by a positive blood culture and is one of the leading causes of neonatal mortality and morbidity in India.

Conclusion: The importance of procalcitonin in diagnosing neonatal septicaemia cannot be denied.

A minimum lethal dose on mice for five bacterial pathogens were identified with PCR of neonatal septicemia of Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa, Citrobacter freundii and Moraxella catarrhalis were studied.

Background: Neonatal septicemia is a major health problem.

Neonatal septicemia constitutes a significant cause of neonatal mortality & morbidity in developing countries.

OBJECTIVE  To examine the use of therapeutic plasma exchange (TPE) as adjunctive therapy in neonatal septic shock.

OBJECTIVE This study aimed to investigate the predictive value of joint detection of serum amyloid A (SAA), plasma procalcitonin (PCT), and whole blood hypersensitive C-reactive protein (hs-CRP) in the diagnosis and efficacy of neonatal septicemia.

Over the past decade, Klebsiella species, especially ESBL producers have emerged as an important cause of neonatal septicemia.

CRP measurement also helps in differential diagnosis, in the management of neonatal septicaemia and meningitis where standard microbiological investigations are very much time-consuming.

A minimum lethal dose on mice for five bacterial pathogens were identified with PCR of neonatal septicemia of Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa, Citrobacter freundii and Moraxella catarrhalis were studied.

We report a case of neonatal septicemia by multidrug-resistant vancomycin-resistant Enterococcus faecium (VRE), the source of infection being the mother’s gut.

Objective To study the predictive value of hemodynamic monitoring in the responsiveness of fluid therapy in neonatal septic shock.

RESULTS: The incidence of neonatal septicemia due to Acinetobacter species was 13.

Introduction: Antimicrobials are the mainstay treatment in neonatal septicemia (NS).

Conclusion The importance of procalcitonin in diagnosing neonatal septicaemia becomes more useful when it is used along with other investigations.

Nowadays Coagulase-Negative Staphylococci (CoNS) has become one of the major pathogen for neonatal septicemia as a result of increased use of intravascular devices and other invasive procedures.

Multivariate Logistic regression was used to analyze the effects of various factors on the occurrence of neonatal septic shock.

Background & Objectives: Neonatal septicemia is responsible for 1.

Background Neonatal septicemia is one of the most common leading reasons for neonatal morbidity and mortality in developing countries.

In pregnant patients, infections tied to Capnocytophaga species from human flora have been associated with preterm labor, chorioamnionitis, and neonatal septicemia.

Early neonatal septic shock detection and polymyxin B–immobilized fiber column direct hemoperfusion induction may improve the prognosis of affected infants.

Septic arthritis is already studied, but there is under reporting of neonatal septic arthritis from under developed regions.

coli isolates causing neonatal septicemia.

The Enterococcus fecalis is a kind of nosocomial opportunistic pathogen and can cause neonatal septicemia with high mortality.

Conditional logistic regression analysis demonstrated statistically significant associations of neonatal septicemia (odds ratio [OR] = 4.

Objective To investigate the diagnostic value of lactate level in arterial blood for the prognosis of neonatal septic shock.

Introduction: Acinetobacter species are opportunistic pathogen, which are gaining importance in hospital acquired neonatal septicemia due to multidrug resistance and causing increased morbidity as well as mortality.

This study aims to provide some insight into the level of risk associated with typical indications for neonatal septic workup at our institution.

All these subjects were suspected to have neonatal septicaemia.

Bacteriological profile of neonatal septicaemia.

Introduction: Neonatal septicemia is defined as “a clinical syndrome of bacteremia with systemic signs and symptoms of infection in the first four weeks of life”.

Neonatal septicemia lacks typical manifestations.