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Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism



Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Familial Parkinson’s Disease Patients Display α-Synuclein Pathology and Abnormal Mitochondrial Morphology


Midbrain Dopaminergic sentence examples within neurodegenerative disorder characterized



Deficiency of miR-29 a/b1 Leads to Premature Aging and Dopaminergic Neuroprotection in Mice



Lactiplantibacillus plantarum PS128 Alleviates Exaggerated Cortical Beta Oscillations and Motor Deficits in the 6-Hydroxydopamine Rat Model of Parkinson’s Disease


Midbrain Dopaminergic sentence examples within Mouse Midbrain Dopaminergic



Cell-type-specific disruption of PERK-eIF2α signaling in dopaminergic neurons alters motor and cognitive function



Small-Molecule Inhibitors of the RNA M6A Demethylases FTO Potently Support the Survival of Dopamine Neurons



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Midbrain Dopaminergic sentence examples within Ventral Midbrain Dopaminergic



Novel insights in the pathophysiology of α-synuclein dysregulation on D2 receptor activity contributing to the vulnerability of dopamine neurons



α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability


Midbrain Dopaminergic sentence examples within midbrain dopaminergic neuron



Where Dopaminergic and Cholinergic Systems Interact: A Gateway for Tuning Neurodegenerative Disorders



The Development of the Mesoprefrontal Dopaminergic System in Health and Disease


Midbrain Dopaminergic sentence examples within midbrain dopaminergic neuronal



Chronic–Progressive Dopaminergic Deficiency Does Not Induce Midbrain Neurogenesis



The intestinal luminal sources of α-synuclein: a gastroenterologist perspective.


Midbrain Dopaminergic sentence examples within midbrain dopaminergic system



The Dopamine Hypothesis of Autism Spectrum Disorder Revisited: Current Status and Future Prospects



GDNF and alcohol use disorder


Midbrain Dopaminergic sentence examples within midbrain dopaminergic afferent



Make a Left Turn: Cortico-Striatal Circuitry Mediating the Attentional Control of Complex Movements.



The Cerebellar Dopaminergic System


Midbrain Dopaminergic sentence examples within midbrain dopaminergic cell



Optogenetic stimulation of glutamatergic neurons in the cuneiform nucleus controls locomotion in a mouse model of Parkinson’s disease



Optogenetic stimulation of glutamatergic neurons in the cuneiform nucleus controls locomotor movements in a mouse model of Parkinson’s disease



Where Dopaminergic and Cholinergic Systems Interact: A Gateway for Tuning Neurodegenerative Disorders



The Development of the Mesoprefrontal Dopaminergic System in Health and Disease



Chronic–Progressive Dopaminergic Deficiency Does Not Induce Midbrain Neurogenesis



The factors for the early and late development of midbrain dopaminergic neurons segregate into two distinct evolutionary clusters



Interaction Between Coxsackievirus B3 Infection and α-Synuclein in Parkinson’s Disease



Make a Left Turn: Cortico-Striatal Circuitry Mediating the Attentional Control of Complex Movements.


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10.1016/j.neulet.2021.135676

Generation of region-specific and high-purity neurons from human feeder-free iPSCs


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10.1097/MD.0000000000025585

SORL1 mutations are associated with parkinsonian and psychiatric features in Alzheimer disease



Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease



Phasic Responses of Mesolimbic Dopamine Neurons are Recruited in Parallel to Sensorimotor Pathways Mediating Cued Approach



The intestinal luminal sources of α-synuclein: a gastroenterologist perspective.



Aging is associated with a degeneration of noradrenergic-, but not dopaminergic-neurons, in the short-lived killifish Nothobranchius furzeri



Cellular and synaptic mechanisms for Parkinson’s disease-related chronic pain



Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk



Compartmentalized microfluidic chambers enable long-term maintenance and communication between human pluripotent stem cell-derived forebrain and midbrain neurons.


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10.1016/j.neuropharm.2021.108705

Blockade of pre-synaptic and post-synaptic GABAB receptors in the lateral habenula produces different effects on anxiety-like behaviors in 6-hydroxydopamine hemiparkinsonian rats



Midbrain dopaminergic innervation of the hippocampus is sufficient to modulate formation of aversive memories



Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk


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10.1007/978-1-0716-1495-2_8

Differentiation of Midbrain Dopaminergic Neurons from Human iPS Cells.


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10.1146/annurev-psych-032921-050951

Memory and Reward-Based Learning: A Value-Directed Remembering Perspective.



Impaired dopamine metabolism is linked to fatigability in mice and fatigue in Parkinson’s disease patients



Dopaminergic regulation of vestibulo-cerebellar circuits through unipolar brush cells


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10.1016/j.pnpbp.2021.110406

Characterisation of methylphenidate-induced excitation in midbrain dopamine neurons, an electrophysiological study in the rat brain



Methods to Induce Small-Scale Differentiation of iPS Cells into Dopaminergic Neurons and to Detect Disease Phenotypes.



Optogenetic stimulation of glutamatergic neurons in the cuneiform nucleus controls locomotion in a mouse model of Parkinson’s disease



Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration



Cell-attached and Whole-cell Patch-clamp Recordings of Dopamine Neurons in the Substantia Nigra Pars Compacta of Mouse Brain Slices.



What Is the Role of Thalamostriatal Circuits in Learning Vocal Sequences?



Primary motor cortex in Parkinson’s disease: Functional changes and opportunities for neurostimulation



Subcellular proteomics of dopamine neurons in the mouse brain reveals axonal enrichment of proteins encoded by Parkinson’s disease-linked genes



Mouse Embryonic Stem Cells Expressing GDNF Show Enhanced Dopaminergic Differentiation and Promote Behavioral Recovery After Grafting in Parkinsonian Rats



Generation of Cortical, Dopaminergic, Motor, and Sensory Neurons from Human Pluripotent Stem Cells.


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10.1016/j.neulet.2021.136045

Nurr1 downregulation is caused by CREB inactivation in a Parkinson’s disease mouse model



Chromatin architecture in addiction circuitry elucidates biological mechanisms underlying cigarette smoking and alcohol use traits



Subcellular and regional localization of mRNA translation in midbrain dopamine neurons


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10.1523/JNEUROSCI.2694-20.2021

Cell Type-Specific Decrease of the Intrinsic Excitability of Motor Cortical Pyramidal Neurons in Parkinsonism


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10.1523/JNEUROSCI.0267-20.2020

Abnormal Cortico-Basal Ganglia Neurotransmission in a Mouse Model of l-DOPA-Induced Dyskinesia


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10.1523/JNEUROSCI.2770-20.2021

VGLUT2 Is a Determinant of Dopamine Neuron Resilience in a Rotenone Model of Dopamine Neurodegeneration



The dopamine dip amplitude is a quantitative measure of disappointment


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10.1016/j.celrep.2021.109697

The transcription factor BCL11A defines distinct subsets of midbrain dopaminergic neurons.



Embryoid Body Formation from Mouse and Human Pluripotent Stem Cells for Transplantation to Study Brain Microenvironment and Cellular Differentiation.



The Cerebellar Dopaminergic System



Comparison of Rat Primary Midbrain Neurons Cultured in DMEM/F12 and Neurobasal Mediums



Current State-of-the-Art and Unresolved Problems in Using Human Induced Pluripotent Stem Cell-Derived Dopamine Neurons for Parkinson’s Disease Drug Development



Synapsin III Controls Early Phases of Dopaminergic Neurons Development in Fishes and Mammals by Acting Upstream of BDNF and Cdk5 Signaling



Chinese Medicine PaBing-II Protects Human iPSC Derived Dopaminergic Neurons from Oxygen Stress



Genetic Imaging of Neuroinflammation in Parkinson’s Disease: Recent Advancements



Optogenetic stimulation of glutamatergic neurons in the cuneiform nucleus controls locomotor movements in a mouse model of Parkinson’s disease



Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor dysfunction and cortical atrophy, independent of protein aggregation



Long non-coding RNA repertoire and open chromatin regions constitute midbrain dopaminergic neuron - specific molecular signatures



The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling



Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson’s disease patients



α-Conotoxin TxIB: A Uniquely Selective Ligand for α6/α3β2β3 Nicotinic Acetylcholine Receptor Attenuates Nicotine-Induced Conditioned Place Preference in Mice



Chloroquine modulates inflammatory autoimmune responses through Nurr1 in autoimmune diseases


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10.1016/B978-0-12-815305-5.00017-8

The experimental evidence for photobiomodulation-induced cellular and behavioral changes in animal models of Parkinson’s disease: a template for translation to patients



Neural circuits and nicotinic acetylcholine receptors mediate the cholinergic regulation of midbrain dopaminergic neurons and nicotine dependence



GDNF and alcohol use disorder



Complementary motivational roles of nigroaccumbens and nigrostriatal dopaminergic pathways


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10.1016/j.chembiol.2019.02.002

Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite.



Biophysical Properties of Somatic and Axonal Voltage-Gated Sodium Channels in Midbrain Dopaminergic Neurons



Crosstalk of Intercellular Signaling Pathways in the Generation of Midbrain Dopaminergic Neurons In Vivo and from Stem Cells



Laminin α2 controls mouse and human stem cell behaviour during midbrain dopaminergic neuron development



Intranigral Injection of Endotoxin Suppresses Proliferation of Hippocampal Progenitor Cells



Quantitative analysis on secretion level of CDNF regulated by two key α‐helices in CDNF protein



A30P mutant α-synuclein impairs autophagic flux by inactivating JNK signaling to enhance ZKSCAN3 activity in midbrain dopaminergic neurons



LIR-dependent LMX1A/LMX1B autophagy crosstalk shapes human midbrain dopaminergic neuronal resilience



Characterization of AN317, a novel selective agonist of α6β2-containing nicotinic acetylcholine receptors.


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10.1016/j.neuron.2019.08.036

Learning from Action: Reconsidering Movement Signaling in Midbrain Dopamine Neuron Activity



High Fat Diet Suppresses Peroxisome Proliferator-Activated Receptors and Reduces Dopaminergic Neurons in the Substantia Nigra



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