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10.1016/J.MSEC.2019.05.004

Ethanol treatment after microsphere formation significantly increased β-sheet and silk II structure (high crystallinity) of the microspheres, significantly reducing the burst release and resulting in zero-order sustained release of octreotide over 102 days, and the data could be fit to the diffusion-driven release model.

Control of octreotide release from silk fibroin microspheres.

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10.1002/jcp.28687

We proceeded to show that both si‐MALAT1 and miR‐20b‐5p‐mimic attenuated microsphere formation and self‐renewal capacity, decreased the proportion of CSCs, and downregulated the expression of proteins associated with tumor cell stemness maintenance (Oct4, Nanog, sex‐determining region Y‐box 2, and Notch1) and cellular metabolism (glucose transporter 1, lactate dehydrogenase B, hexokinase 2, and pyruvate kinase isozyme M2) in HCT‐116 cells in vitro.

Long noncoding RNA MALAT1 mediates stem cell‐like properties in human colorectal cancer cells by regulating miR‐20b‐5p/Oct4 axis

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10.3760/CMA.J.ISSN.1001-9030.2019.11.017

The stem cell characteristics of breast cancer cells was analyzed by microsphere formation assay.

Effect of p21-activated protein kinase 4 on proliferation and stem cell characteristics of breast cancer cells

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Microsphere Formation - Ethanol treatment after microsphere formation significantly increased β-sheet and silk II structure (high crystallinity) of the microspheres, significantly reducing the burst release and resulting in zero-order sustained release of octreotide over 102 days, and the data could be fit to the diffusion-driven release model. [1] We proceeded to show that both si‐MALAT1 and miR‐20b‐5p‐mimic attenuated microsphere formation and self‐renewal capacity, decreased the proportion of CSCs, and downregulated the expression of proteins associated with tumor cell stemness maintenance (Oct4, Nanog, sex‐determining region Y‐box 2, and Notch1) and cellular metabolism (glucose transporter 1, lactate dehydrogenase B, hexokinase 2, and pyruvate kinase isozyme M2) in HCT‐116 cells in vitro. [2] The stem cell characteristics of breast cancer cells was analyzed by microsphere formation assay. [3]