Introduction to Metastatic Malignancy

Methods: Patients treated with immunotherapy for metastatic malignancy in MMUH between March 2013 and September 2020 were retrospectively drawn.

The differential diagnosis of ring-enhancing brain lesions in a patient with metastatic malignancy may initially seem straightforward, and easily attributed to brain metastases.

Advances in cancer immunotherapy treatments have shown promising results in patients with metastatic malignancy who have been refractory to prior treatments.

Agents targeting the epidermal growth factor receptor (EGFR) are administered in patients with advanced, recurrent, and metastatic malignancy.

While we were focusing on tapering of the immunosuppressive medication as a possible trigger, this episode was most likely triggered by the possible metastatic malignancy – especially given the lag of almost 2 years between reduction in hydroxychloroquine and steroids and development of symptoms.

Out of 293 biopsies, 246 patients were found to have malignancy (84%), including 210 (72%) patients with metastatic malignancy and 36 with primary hepatic malignancies (20 HCC and 16 others).

The second patient had a history of metastatic malignancy and presented with a large sellar mass with suprasellar extension causing displacement of the optic chiasm.

Methods In this cross-sectional study of ED patients with end-stage disease (eg, palliative care, metastatic malignancy, home oxygen, dialysis) conducted during purposefully sampled random accrual times we performed a standardized, timed review of available health records, including accompanying transfer documents.

Anti-programmed cell death-1 (PD-1) and PD-1 ligand (PD-L1) inhibitors such as pembrolizumab have shown promising results as second-line therapy for patient with metastatic malignancy.

Aim and Objectives: This retrospective research analyzes the cytological features of hepatic masses, with particular reference to pattern assessment, cellular and nuclear details along with background characteristics of note which could define differentiating characteristics of hepatocellular carcinoma from metastatic malignancy.

Other causes of unexplained ALI were detected by computed tomography (CT) imaging and included newly diagnosed significant atherosclerotic disease (19%), embolism from isolated proximal large vessel thrombus (10%) and metastatic malignancy (10%).

INTRODUCTION Although the diagnostic utility of lymph node fine-needle aspiration (FNA) is well established in the evaluation of metastatic malignancy, its value in the diagnosis of lymphoma is more controversial; yet, there is a growing trend among practitioners towards less-invasive procedures such as FNA and core needle biopsy (CNB).

Myocarditis: 2 case reports In a case series, two female patients aged 46-68 years were described, who developed drug-related myocarditis during treatment with sintilimab or pembrolizumab for beast cancer or metastatic malignancy of supraclavicular lymph node, respectively.

Methods and Objectives: This was a single institution retrospective study that evaluated the impact of antibiotics on outcomes of patients with advanced or metastatic malignancy who were treated with ICB.

We aimed to evaluate short term outcomes of percutaneous coronary intervention (PCI) with drug-eluting stents (DES) in patients with localized and metastatic malignancy.

Nodules known to be inflammatory or associated with a metastatic malignancy were excluded.

Further evaluation of a painless subcutaneous lesion is imperative to rule out rare conditions and the possibility of recurrent or metastatic malignancy.

Oral metastatic lesions have a wide differential diagnosis, and awareness of this rare presentation can help clinicians maintain an index of suspicion for an underlying metastatic malignancy.

It can mimic metastatic malignancy especially when it presents at old age.

Firstly, a wide differential diagnosis including infection (Listeria cerebritis), extra-articular manifestations of her rheumatoid arthritis (RA), including rheumatoid vasculitis, metastatic malignancy or a lymphoproliferative disorder.

We describe a case of a 71-year-old woman where the initial presentation of destructive arthropathy and spinal masses secondary to axial gout was mistaken for a metastatic malignancy.

Multivariable conditional logistic regression analysis was performed and there was a large variation in the influence of different risk factors associated with ICU-admission, renal disease, liver disease, metastatic malignancy, substance abuse, and congestive heart failure showed the strongest associations.

Patients were subsequently divided based on local malignancy and metastatic malignancy.

PURPOSE/OBJECTIVE(S) Use of local therapy such as stereotactic body radiation therapy (SBRT) to treat oligometastatic malignancy is a well-established paradigm, but whether benefit extends to the oligoprogressive setting remains unclear.

Methods: In this phase 1 study, Chinese patients with advanced, recurrent or metastatic malignancy that were histologically or cytologically confirmed and harboring FGF/ FGFR 1-3 variation were enrolled.

卵巢转移瘤合并原发瘤（ovarian metastatic malignancy with primary tumor，OMMPT）是一种罕见现象，指卵巢转移瘤伴发卵巢原发性肿瘤。本组1例为卵巢转移性结肠腺癌伴成年型颗粒细胞瘤（AGCT），另1例为子宫体子宫内膜样癌（EC）转移至卵巢成熟性囊性畸胎瘤（MCT），并复习文献以提高对该病的认识，为治疗及预后提供依据。.

However, avoidance is recommended in patients with a history of melanoma, lymphoma, or metastatic malignancy.

80%), and 2 cases of metastatic malignancy (0.

Background Ovarian cancer, a highly metastatic malignancy, has benefited tremendously from advances in modern human genomics.

Haematogenous tumour spread is a hallmark of metastatic malignancy and a key factor in cancer recurrence and prognosis.

Conclusion: MFI combined with DLA provides a potential tool to assist in cytological diagnosis of metastatic malignancy in body fluid samples.

1% (n=8) did not have serum calcium measured at any point; two of which had lung cancer (including one metastatic malignancy).

Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic malignancy.

The majority of vPEGs were for patients with obstruction secondary to locally advanced or metastatic malignancy (n=21/27, 77.

Since SLR is known to occur in several neoplasias and occasionally causes lymphadenopathy and mimics metastatic malignancy, it needs to be considered whether lymphadenopathy is due to metastasis or SLR for the choice of cancer treatment.

Regarding serology, the titer of anti-echinococcal antibodies was positive (22, n = 11) Conclusions: Clinical presentation and radiologic imaging findings of disseminated alveolar echinococcosis can mimic metastatic malignancy, and diagnosis can be challenging in atypically advanced cases.

BACKGROUND Patients with acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) suffer from a significant symptom burden and psychological, spiritual, social needs comparable to patients with solid metastatic malignancy.

Introduction: Frozen section (FS) is an important and rapid intra-operative tool to assess primary pathology/ malignancy, diagnose metastatic malignancy and to ensure negative resection margins during the respective surgeries for gastric and gastrooesophageal malignancies, which can subsequently impact patient prognosis and management.

The sample showed metastatic malignancy 3.

Metastatic malignancy to the epidural or leptomeningeal spaces is more common than primary cord tumors.

Background: Central airway obstruction (CAO) is defined as obstruction of the airway lumen in the trachea or mainstem bronchi, most commonly due to primary or metastatic malignancy; and is classified as extraluminal, endoluminal, or mixed.

These patients were palliative with widespread metastatic malignancy.

5%) and metastatic malignancy (2.

Here, we report a case of eosinophilic granulomatosis with polyangiitis in a patient with disseminated non-tuberculous mycobacterial infection in multiple sites mimicking metastatic malignancy and describe the associated PET/CT scan findings before and after treatment.

We emphasize a discussion of future directions for research on these cytokines, to bring them to fruition as major contributors for the treatment of metastatic malignancy.

Incidental finding of appendiceal pathology at time of laparoscopy for endometriosis is not uncommon; however, the finding of metastatic malignancy is far rarer.

We excluded patients who had domiciliary ventilation, survival-limiting comorbidities (such as metastatic malignancy), and a primary reason for admission other than AECOPD.

Adrenocortical carcinoma or a metastatic malignancy was high on the differential diagnoses list.

Subsequent computed tomography of the chest, abdomen, and pelvis showed metastatic malignancy, and in the context of a significantly elevated serum cancer antigen 19-9, we suspected a pancreatic primary cancer.

Patients with metastatic malignancy of breast.

Breast cancer is the most common orbital metastatic malignancy and as the prevalence of breast cancer rises, the incidence of orbital metastasis is expected to increase concomitantly.

Mediastinal mass with lesions disseminated throughout the body is an unusual presentation of extranodal RDD that calls for a challenging differential diagnosis to rule out the suspicion of metastatic malignancy.

Inhibiting components of these circuits defines new therapeutic opportunities for melanoma with metastatic malignancy.

Patients with metastatic malignancy of the breast 2.

In 1993, we experienced laparoscopic partial liver resection for both of primary and metastatic malignancy, with liver cirrhosis occasionally.

INTRODUCTION The lymphangitic carcinomatosis (LC) pattern of metastatic malignancy is associated with a poor prognosis but is currently not well defined in malignant pleural mesothelioma (MPM).

This case was an excellent exercise in therapeutic decision-making amidst a dynamic disease process that required integration of numerous clinical and diagnostic data points, including empiric anticoagulation with high clinical suspicion of acute pulmonary embolism, review of contraindications to anticoagulation and thrombolysis in metastatic malignancy, and the decision to pursue mechanical thrombectomy in the setting of contraindications to catheter-directed thrombolysis.

Overall, use of IVC filters was more common in cancer patients who developed bleeding complications on anticoagulation and with metastatic malignancy.

Results: Primary lung cancer was diagnosed in 64 patients and metastatic malignancy in 3 patients.

Main outcome measures Prostate cancer diagnosis, age of onset, and androgen deprivation therapy (serving as proxy for advanced or metastatic malignancy).

The current description confirms the rarity of metastatic malignancy of the hand and its poor prognosis.

4 We present the case of a child with an undifferentiated, metastatic malignancy showing rhabdoid and neuroendocrine features exhibiting a partial response to carboplatin, etoposide phosphate, and atezolizumab.

PURPOSE To analyze clinical factors that were associated with inadequate pain control in cancer patients with metastatic malignancy and moderate to severe baseline pain.

Chemoradiation was selected to treat 15% of patients, especially those with lymphoma (93%), metastatic malignancy (93%), and urothelial carcinoma (69%).

Acute viral hepatitis and thrombosis of the portal system were excluded in complementary investigation, as well as sepsis, metastatic malignancy and other liver diseases, setting a RUCAM score of 6.