Introduction to Long Term Systemic
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Long Term Systemic sentence examples within long term systemic effect
Anti-VEGF therapies are implemented worldwide despite insufficient knowledge of choice of drug, dosage and long term systemic effects.
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The soluble lipid forms of the pesticides in the organophosphate group, especially, can lead to long term systemic effects by accumulating in the liver and brain (6).
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Hair cortisol concentration (HCC) is a marker of long-term systemic cortisol production.
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The only curative treatment is surgery; however, most patients are diagnosed with metastatic disease, therefore, preclinical and clinical research have investigated the molecular pathways associated with NETs development, which lead to discovering multiple long-term systemic therapeutic options.
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As such, 25 research priorities
have been identified with a view to addressing recovery challenges and informing long-term systemic change.
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The presence of persistent technical inefficiency arising from long-term systemic problems and government-related regulatory constraints does not appear to have been addressed.
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Furthermore, we do not yet have any experience with the long-term systemic effects of the treatment.
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The long-term systemic use of antibiotics may lead to antibiotic resistance and has limited effects on eradicating local biofilms.
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(1) Establish long-term systemic environmental and human health objectives and indicators.
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This study evaluated the timetable of SIOH and steroid-induced posterior subcapsular cataract (SI-PSC) occurrences in children with systemic autoimmune diseases (SAD) undergoing long-term systemic corticosteroid treatment.
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This case report elaborates on the risks of the development of opportunistic ocular infections in patients receiving long-term systemic immunosuppressants and the need for regular ocular examinations in such cases.
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This concept is also the reason why my colleagues and I have for several years administered long-term systemic maintenance immunotherapy for patients with vitreoretinal lymphoma”.
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To understand the impact of adversity on the HPA-axis, we examined associations between early-life and recent adversity with hair cortisol concentration, an indicator of long-term systemic cortisol levels.
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This concept is also the reason why my colleagues and I have for several years administered long-term systemic maintenance immunotherapy for patients with vitreoretinal lymphoma [5].
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4 % of patients were able to discontinue GC therapy, consistent with earlier studies suggesting that IVIG therapy might help to reduce long-term systemic GC administration [8, 9].
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Using orthotopic murine models humanized for CD40 and Fcγ receptors, we demonstrate that intravesical treatment with a fully human, Fc-enhanced anti-CD40 agonist antibody (2141-V11) induces robust antitumor activity in both treatment-naïve and treatment-refractory settings, driving long-term systemic antitumor immunity with no evidence of systemic toxicity.
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This study explored long-term systemic toxicity, effects on the endocrine system, and toxicokinetic behavior after repeated subcutaneous administration of butylparaben to Sprague-Dawley rats.
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The current standard treatment requires high-dose and long-term systemic corticosteroids, which may lead to adverse effects and intolerability of patients.
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The use of neoadjuvant chemotherapy prior to resection may increase the likelihood of long-term systemic disease control.
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The results were consistent across different subgroups of patients, including male gender, ages more than 40 years, and those receiving long-term systemic disease-modifying antirheumatic drugs and phototherapies.
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Methods and analysis This review will be among the first to summarise literature on the psychological issues in the growing group of advanced cancer patients undergoing long-term systemic treatment.
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The existing fracture-related infection treatment algorithm combined with long-term systemic antifungal therapy has an anecdotal value and needs more extensive studies to be validated.
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Compared with other patients with BP, those with BP and comorbid AD and AR were more frequently managed by adjuvant drugs and long-term systemic and topical corticosteroids and had decreased all-cause mortality.
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PURPOSE
Dexamethasone (Dex) is a widely used drug for the treatment of inflammatory and autoimmune conditions, however, long-term systemic use of Dex is associated with serious adverse effects.
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BACKGROUND
Rheumatoid arthritis is a long-term systemic disease that primarily affects multiple synovial joints throughout the body.
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13% benzalkonium chloride (BAC) to assess the effect of dermal absorption on long-term systemic exposure to BAC.
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Current clinical practice relies on long-term systemic immunosuppression, leading to severe adverse events.
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They also provide recommendations which reflect the coordination of work by teachers and teacher educators that address researched-based practices for long-term systemic change.
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Providing an account of the policy response to COVID-19 in England, this book analyses the political and long-term systemic factors associated with the failures to control the first wave of the pandemic during 2020 It explores the part played by key policy actors, particularly politicians and scientists, and focuses on two difficult policy issues during the first wave: the establishment of a 'test, trace and isolate' system and responses to the high death rate in care homes for older people Drawing on a wide range of documentary evidence, including parliamentary papers and SAGE minutes, this book draws attention to the importance of longstanding structural problems in public health and the care sector, especially the impact of outsourcing and privatisation © 2020 Bristol University Press.
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The commonly used antibiotic therapy cannot effectively treat these diseases within a short time, and also bring about adverse effects such as drug resistance and immune system damage during long-term systemic treatment.
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Main Outcomes and Measures
Poor control was defined as polyp recurrence (polyp growth in >1 sinus area on a single side), use of long-term systemic therapy (biologic therapy or ≥3 consecutive months of oral corticosteroids), and revision surgery involving polypectomy.
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Anesthesia providers should therefore be cognizant of immediate, and long-term systemic effects of cancer therapies (organ toxicities), and the effects of chemo-radiation on nutrition, fatigue, anemia, and physical deconditioning all of which could influence the recovery profile after major surgery.
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Fontan-associated liver disease (FALD) caused by long-term systemic venous congestion following the Fontan procedure may eventually lead to hepatocellular carcinoma (HCC).
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Early treatment for PD is efficient; however, long-term systemic medication commonly leads to deleterious side-effects.
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Low-carbon transitions demand long-term systemic transformations and meaningful societal engagement.
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Functional analysis of these genes reveals possible long-term systemic effects of the infection, such as vascular remodelling and fibrosis.
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Findings from this review assume that influenza vaccine works safely and efficiently among patients with long-term systemic corticosteroid therapy at a low dose, 10mg/day might be a boundary value.
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Over years many therapeutic regimens such as local and long-term systemic steroids (10 mg/day) and PUVAphotochemotherapy combined with acitretin (approved treatment option in Germany) were used without sufficient effect.
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Female gender, presence of bronchiectasis, low BMI and long-term systemic corticosteroid treatment were independent risk factors associated with NTM-PD.
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Among CLE-alone patients, females and those taking long-term systemic corticosteroids (a proxy for extensive disease) were associated with non-SLE autoimmune diseases after adjusting for the number of repeated autoimmune laboratory tests.
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We assume that approximately 8% of subjects randomized to the PSMA PET arm will be found to have M1 disease and thus will be more appropriate candidates for long-term systemic or multimodal therapy, rather than curative intent dRT.
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No short- or long-term systemic or local complications were observed following TVA in any of the mares used in this study.
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With the presence of long-term systemic comorbidities, the incidence of pathological conditions also increases.
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This review addresses the acute and long-term systemic and coronary hemodynamic effects of tobacco, with an emphasis of the impact on coronary blood flow and pathophysiologic mechanisms.
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Low Intensity Laser therapy doesn’t affect hyperuricemia or guarantee long-term systemic anti-inflammatory effect, but help to additionally relieve pain in joints and thus enhance treatment effect and quality of patients’ life.
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Design/methodology/approach
This study uses constructivist grounded theory (Charmaz and Belgrave, 2012) to create a long-term systemic analysis of university innovation efforts.
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However, long-term systemic neutralization of IL-1β by Canakinumab may cause severe adverse events such as serious upper respiratory tract infections and inflammation, thereby decreasing the quality of life of patients.
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We assume that approximately 8% of subjects randomized to the PSMA PET arm will be found to have M1 disease and thus will be more appropriate candidates for long-term systemic or multimodal therapy, rather than curative intent dRT.
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Stable period periostin levels were significantly higher in eosinophilic patients and eosinophilic patients without long-term systemic steroid therapy had higher IL-13 levels.
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Of the patients who were on long term systemic steroids, 35.
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BBackground and Rationale: From the medicolegal point of view, long term systemic consequences of scald injury should be identified for proper compensation and legal action, especially for scald injury involving skin full-thickness in 20% of total body surface area (TBSA) which is known to have long term grave consequences on general health.
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Anti-VEGF therapies are implemented worldwide despite insufficient knowledge of choice of drug, dosage and long term systemic effects.
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While the INTACT project and collaborative navigation projects both achieved respectable performance during their respective testing, the individual systems had notable drawbacks, such as requiring illumination within the environment to be relatively high for proper operation of the visual odometry within the INTACT system, and the long term systemic drift of the collaborative navigation systems when the entire team was isolated from absolute position reference for an extended period of time.
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The soluble lipid forms of the pesticides in the organophosphate group, especially, can lead to long term systemic effects by accumulating in the liver and brain (6).
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