Lipofibromatous Hamartoma in a Sentence

What is/are Lipofibromatous Hamartoma?

Lipofibromatous Hamartoma - CASE Lipofibromatous hamartoma (LFH) is a rare benign tumor of the peripheral nerves, which often affects upper extremity. ^[1] Lipofibromatous Hamartoma of the Upper Extremity: Report of Two Cases. ^[2] Lipofibromatous hamartoma (LFH) is a benign tumor that causes nerve enlargement due to fatty adipose tissue infiltration around bundles of peripheral nerves. ^[3] Lipofibromatous hamartoma is an uncommon tumor that causes nerve enlargement due to fatty adipose tissue infiltration in peripheral nerves being the median nerve at the carpal tunnel the most commonly affected site, typically associated with macrodactyly. ^[4] If surgery is undertaken, our case report suggests that unlike radical excision of infiltrating nerve tumours, for example neurofibromas or lipofibromatous hamartomas, neuritis ossificans can potentially be completely enucleated from the ulnar nerve without resulting in neurological deficits. ^[5] The lipofibromatous hamartoma refers to the benign proliferation of mature adipocytes within peripheral nerves, infiltrating the endoneurium, perineurium, and epineurium, and resulting in fusiform nerve enlargement. ^[6] Lipofibromatous Hamartoma (LFH) is a rare tumour affecting the peripheral nerves, mostly the median nerve. ^[7] Results: All 43 pathologies were benign, and histopathologic diagnoses were 10 lipomas, 8 ganglions, 5 giant cell tumor of the tendon sheath, 4 schwannomas, 3 hemangiomas, 3 palmar fibromatosis, 2 epidermal cysts, 2 neurofibroma, 1 angiolymphoid hyperplasia with eosinophilia, 1 granuloma, 1 calcifying aponeurotic fibroma, 1 digital fibroma, 1 foreign body granuloma, and 1 lipofibromatous hamartoma. ^[8] As a matter of fact, lipomatosis of nerves have been reported in literature with a variety of definitions, as macrodystrophia lipomatosa, fibrolipoharmartoma, lipofibromatous hamartoma, fibrofatty tumor, lipofibroma, or lipofibromatous hamartoma. ^[9] Lipofibromatous hamartoma is a rare fibro-fatty tumor. ^[10] Lipofibromatous hamartoma (LFH) is a rare, benign tumor found in the peripheral nerves which is challenging to diagnose. ^[11] Besides the term lipomatosis of nerve,which has been proposed byWHO in 2002 [2], many other terms are regularly used including fibrolipomatous hamartoma, lipofibromatous hamartoma, neural lipoma, and macrodystrophia lipomatosa, for a spectrum of pathologies. ^[12]