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Chemically Designed Nanoscale Materials for Controlling Cellular Processes.



Molecular Mechanisms of Borrelia burgdorferi Phagocytosis and Intracellular Processing by Human Macrophages



Caveolae-Mediated Endocytosis Drives Robust siRNA Delivery of Polymeric Nanoparticles to Macrophages.



Multispectral Fingerprinting Resolves Dynamics of Nanomaterial Trafficking in Primary Endothelial Cells.



A high-throughput Galectin-9 imaging assay for quantifying nanoparticle uptake, endosomal escape and functional RNA delivery



Two-Pore Channels Regulate Expression of Various Receptors and Their Pathway-Related Proteins in Multiple Ways



The SARS-CoV-2 envelope and membrane proteins modulate maturation and retention of the spike protein, allowing assembly of virus-like particles



Unlocking the potential of antibody–drug conjugates for cancer therapy



Phagocytosis and the antigen-processing abilities of macrophages derived from monocytes in spinal tuberculosis patients


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10.3390/pharmaceutics13070945

Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles


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10.22541/AU.161417238.80994704/V1

In vivo cleavage of solubility tags as a tool to enhance the levels of soluble recombinant proteins in Escherichia coli


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10.1016/j.chembiol.2021.07.016

Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter.



Functions of the (pro)renin receptor (Atp6ap2) at molecular and system levels: pathological implications in hypertension, renal and brain development, inflammation, and fibrosis.



Is It Time to Use Modeling of Cellular Transporter Homeostasis to Inform Drug-Drug Interaction Studies: Theoretical Considerations.



Molecular markers of brain cholesterol homeostasis are unchanged despite a smaller brain mass in a mouse model of cholesteryl ester storage disease.



Giantin is required for intracellular N-terminal processing of type I procollagen



Targeting Non-Canonical Pathways as a Strategy to Modulate the NIS Symporter



Rational design for controlled release of Dicer-substrate siRNA harbored in phi29 pRNA-based nanoparticles



In vivo cleavage of solubility tags as a tool to enhance the levels of soluble recombinant proteins in Escherichia coli


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10.1016/j.chembiol.2019.09.008

Responsive Antibody Conjugates Enable Quantitative Determination of Intracellular Bond Degradation Rate.



Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells.



Structural deciphering of the NG2/CSPG4 proteoglycan multifunctionality



TOWARDS THE RATIONAL DESIGN AND APPLICATION OF POLYMERS FOR GENE THERAPY: INTERNALIZATION AND INTRACELLULAR FATE



Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages



C1R Mutations Trigger Constitutive Complement 1 Activation in Periodontal Ehlers-Danlos Syndrome



Nanocarriers and immune cells



Induction of MET Receptor Tyrosine Kinase Down-regulation through Antibody-mediated Receptor Clustering



Congenital hypofibrinogenemia associated with a novel heterozygous nonsense mutation in the globular C-terminal domain of the γ-chain (p.Glu275Stop)



Misfolded proinsulin impairs processing of precursor of insulin receptor and insulin signaling in β cells



Supraphysiological vitamin B12 serum concentrations without supplementation: the pitfalls of interpretation



Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability



Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity



Familial early-onset hyperuricemia and gout associated with a newly identified dysfunctional variant in urate transporter ABCG2



Clearance by Microglia Depends on Packaging of Phagosomes into a Unique Cellular Compartment.



FGF23 Synthesis and Activity



Norepinephrine-Transporter-Targeted and DNA-Co-Targeted Theranostic Guanidines.



Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor


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10.1158/1078-0432.CCR-18-1976

HER2-Overexpressing/Amplified Breast Cancer as a Testing Ground for Antibody–Drug Conjugate Drug Development in Solid Tumors



How thyroid hormones and their inhibitors affect cartilage growth and shape in the frog Xenopus laevis



Endocytosis Controls Small Interfering RNA Efficiency: Implications for Small Interfering RNA Delivery Vehicle Design and Cell-Specific Targeting.



A Systems Pharmacology Model for Drug Delivery to Solid Tumors by Antibody-Drug Conjugates: Implications for Bystander Effects


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