Insulin Igf Signaling in a Sentence

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10.1093/genetics/iyaa037

Mutations of the Drosophila melanogaster insulin/IGF signaling system slow aging, while also affecting growth and reproduction.

Aging modulated by the Drosophila insulin receptor through distinct structure-defined mechanisms

10.1038/s41467-021-23856-9

We observed similar changes in long-lived mouse models of reduced insulin/IGF signaling.

Regulation of the one carbon folate cycle as a shared metabolic signature of longevity

10.1016/j.ibmb.2021.103611

Further investigation revealed that miR-8 promotes cell growth independent of insulin/IGF signaling.

MicroRNA miR-8 promotes cell growth of corpus allatum and juvenile hormone biosynthesis independent of insulin/IGF signaling in Drosophila melanogaster.

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10.3389/fevo.2021.735924

Here, I review two conserved hormonal pathways, insulin/IGF signaling (IIS) and nuclear hormone receptor signaling (NHR), and their role in regulating diapause across three animal phyla.

Hormonal Regulation of Diapause and Development in Nematodes, Insects, and Fishes

10.1039/d0fo02974b

elegans via insulin/IGF signaling and SKN-1 pathways.

Rhodiola extract promotes longevity and stress resistance of Caenorhabditis elegans via DAF-16 and SKN-1.

10.1007/s00592-021-01750-6

We aimed to investigate the effect of the type 2 diabetes-specific insulin/IGF signaling genetic variants on the hippocampal volume and their relationships with episodic memory in Chinese patients with type 2 diabetes.

Effects of INSR genetic polymorphism on hippocampal volume and episodic memory in chinese type 2 diabetes

10.3390/nu13103468

The LKO mice exhibited a significant gain in body weight compared to Floxed controls at 23 weeks of age and impaired systemic glucose metabolism, which was accompanied by diminished insulin/IGF signaling.

Hepatocyte-Specific Phgdh-Deficient Mice Culminate in Mild Obesity, Insulin Resistance, and Enhanced Vulnerability to Protein Starvation

10.33160/yam.2021.02.009

Recently, we showed that term SGA infants have abnormal insulin/IGF signaling in cord blood.

Cord Blood from SGA Preterm Infants Exhibits Increased GLUT4 mRNA Expression.

10.1039/d0fo03300f

1 act collaboratively with the insulin/IGF signaling pathway (IIS) in a daf-16-independent mode.

HSF-1 and SIR-2.1 linked insulin-like signaling is involved in goji berry (Lycium spp.) extracts promoting lifespan extension of Caenorhabditis elegans.

10.1101/2021.06.07.447366

We show that four irld genes affect starvation resistance by regulating insulin/IGF signaling.

Natural variation in the irld gene family affects insulin/IGF signaling and starvation resistance

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Insulin Igf Signaling - Mutations of the Drosophila melanogaster insulin/IGF signaling system slow aging, while also affecting growth and reproduction. [1] We observed similar changes in long-lived mouse models of reduced insulin/IGF signaling. [2] Further investigation revealed that miR-8 promotes cell growth independent of insulin/IGF signaling. [3] Here, I review two conserved hormonal pathways, insulin/IGF signaling (IIS) and nuclear hormone receptor signaling (NHR), and their role in regulating diapause across three animal phyla. [4] elegans via insulin/IGF signaling and SKN-1 pathways. [5] We aimed to investigate the effect of the type 2 diabetes-specific insulin/IGF signaling genetic variants on the hippocampal volume and their relationships with episodic memory in Chinese patients with type 2 diabetes. [6] The LKO mice exhibited a significant gain in body weight compared to Floxed controls at 23 weeks of age and impaired systemic glucose metabolism, which was accompanied by diminished insulin/IGF signaling. [7] Recently, we showed that term SGA infants have abnormal insulin/IGF signaling in cord blood. [8] 1 act collaboratively with the insulin/IGF signaling pathway (IIS) in a daf-16-independent mode. [9] We show that four irld genes affect starvation resistance by regulating insulin/IGF signaling. [10]