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Role of epigenetic mechanisms in structural and functional plasticity in the CNS: focus on spinal sensitization



A genetic compensatory mechanism regulated by c-Jun and Mef2d modulates the expression of distinct class IIa HDACs to ensure peripheral nerve myelination and repair


Iia Histone sentence examples within iia histone deacetylase



Role of epigenetic mechanisms in structural and functional plasticity in the CNS: focus on spinal sensitization



Novel late-stage radiosynthesis of 5-[18F]-trifluoromethyl-1,2,4-oxadiazole (TFMO) containing molecules for PET imaging


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10.11588/HEIDOK.00029995

Role of epigenetic mechanisms in structural and functional plasticity in the CNS: focus on spinal sensitization


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10.1038/s41598-021-90069-x

Novel late-stage radiosynthesis of 5-[18F]-trifluoromethyl-1,2,4-oxadiazole (TFMO) containing molecules for PET imaging


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10.1101/2021.09.20.461026

A genetic compensatory mechanism regulated by c-Jun and Mef2d modulates the expression of distinct class IIa HDACs to ensure peripheral nerve myelination and repair


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10.1016/j.jmgm.2021.107937

Discovery of novel isoform-selective histone deacetylases 5 and 9 inhibitors through combined ligand-based pharmacophore modeling, molecular mocking, and molecular dynamics simulations for cancer treatment.


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10.1101/2021.04.15.439900

Wilson disease: intersecting DNA methylation and histone acetylation regulation of gene expression in a mouse model of hepatic copper accumulation


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10.1016/j.yjmcc.2021.09.001

Histone deacetylase 4 deletion broadly affects cardiac epigenetic repression and regulates transcriptional susceptibility via H3K9 methylation.


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10.1016/j.yjmcc.2021.08.007

Post-translational modifications talk and crosstalk to class IIa histone deacetylases.


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10.3390/ijms22179509

Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation


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10.1016/j.bmcl.2018.11.009

Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor.


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10.15252/emmm.201809127

Nuclear receptor corepressor 1 represses cardiac hypertrophy


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10.1016/j.cellsig.2019.109357

mAKAPβ signalosomes - A nodal regulator of gene transcription associated with pathological cardiac remodeling.


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10.1152/physiolgenomics.00043.2019

Epigenomic mechanisms of alcohol-induced impaired differentiation of skeletal muscle stem cells; role of Class IIA histone deacetylases.



Conformational dynamics and allosteric effect modulated by the unique zinc-binding motif in class IIa HDACs.


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10.1007/s10048-019-00569-2

Rs10230207 genotype confers changes in HDAC9 and TWIST1, but not FERD3L in lymphoblasts from patients with intracranial aneurysm


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10.3390/ijms20133219

Salt Inducible Kinase Signaling Networks: Implications for Acute Kidney Injury and Therapeutic Potential


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10.1096/fj.201801067RR

Selective inhibition of class IIa histone deacetylases alleviates renal fibrosis


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10.1080/19382014.2019.1617621

Class IIa HDACs do not influence beta-cell function under normal or high glucose conditions


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10.1074/jbc.RA118.007312

Effects of histone deacetylase inhibitor Scriptaid and parathyroid hormone on osteocyte functions and metabolism


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10.3389/fcell.2019.00191

Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling


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10.1016/j.isci.2019.100766

Metastatic Phosphatase PRL-3 Induces Ovarian Cancer Stem Cell Sub-population through Phosphatase-Independent Deacetylation Modulations


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10.1016/j.cr.2018.11.001

Nuclear-cytoplasmic shuttling of class IIa histone deacetylases regulates somatic cell reprogramming


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10.1016/j.celrep.2019.09.023

HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70.


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10.1038/s41467-019-11409-0

Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription


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10.3390/ijms21010238

The Selective Class IIa Histone Deacetylase Inhibitor TMP195 Resensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs



HDAC4 mutations cause diabetes and induce β‐cell FoxO1 nuclear exclusion


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10.1074/jbc.RA119.011519

mTORC2 links growth factor signaling with epigenetic regulation of iron metabolism in glioblastoma


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