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10.3390/ijms20153775

It is well-established that endothelial dysfunction precedes the onset of cardiovascular disease, therefore NOX are important molecular links between type 2 diabetes and vascular complications.

Endothelial Dysfunction: Is There a Hyperglycemia-Induced Imbalance of NOX and NOS?

10.17140/tfmoj-4-128

Our recent report showed in a rat model of renal transplantation that mitochondrial dysfunction precedes compromised proteasome function and this results in a vicious cycle of mitochondrial injury and proteasome dysfunction.

A Cycle of Altered Proteasome and Reactive Oxygen Species Production in Renal Proximal Tubular Cells

10.25177/JNMS.2.1.RV.532

Background: Numerous published studies indicate that microvascular endothelial dysfunction precedes cognitive decline in Alzheimer's disease, and that preservation of a healthy cerebrovascular endothelium can be an important.

NANOTHERAPY TO DELAY COGNITIVE IMPAIRMENT: USING COLLOIDAL NANOCARRIERS TO BLOCK AMYLOID-β-INDUCED DAMAGE IN BRAIN CELL MEMBRANES

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10.1016/j.diabet.2019.12.005

CONCLUSION Reduced lung function precedes and significantly predicts the future development of T2D independently of obesity, smoking and inflammation in community-dwelling middle-aged and elderly people.

Lung function as a predictor of incident type 2 diabetes in community-dwelling adults: A longitudinal finding over 12 years from the Korean Genome and Epidemiology Study.

10.1101/760306

Rods contribute crucially to human vision and their dysfunction precedes cones’ in several retinal diseases.

Optoretinography: optical measurements of human cone and rod photoreceptor responses to light

10.1016/j.atherosclerosis.2019.11.017

BACKGROUND AND AIMS Endothelial dysfunction precedes atherosclerosis and smoking is a well-known risk factor for the development of endothelial dysfunction.

Influence of smoking and smoking cessation on biomarkers of endothelial function and their association with mortality.

10.18585/INABJ.V11I2.576

Long-term hyperglycemia conditions promote endothelial dysfunction precedes to the development of multiple organ dysfunctions.

The Number and Potency of Endothelial Progenitor Cells in Type 2 Diabetes Mellitus Patients

10.1007/s11357-019-00139-2

Here, we review compelling evidence from two lines of inquiry: one that links microvascular rarefaction with insulin-like growth factor 1 (IGF-1) deficiencies, and another which posits that vascular dysfunction precedes hypertension.

The role of exercise in the reversal of IGF-1 deficiencies in microvascular rarefaction and hypertension

10.1139/apnm-2019-0445

These findings indicate that brachial artery dysfunction precedes an inefficient functional sympatholysis.

Impact of High Sodium Intake on Blood Pressure and Functional Sympatholysis during Rhythmic Handgrip Exercise.

10.1007/s12035-019-1550-1

However, ALS is being redefined as a distal axonopathy, in that neuromuscular junction dysfunction precedes and may even influence motoneuron loss.

Overview of Impaired BDNF Signaling, Their Coupled Downstream Serine-Threonine Kinases and SNARE/SM Complex in the Neuromuscular Junction of the Amyotrophic Lateral Sclerosis Model SOD1-G93A Mice

10.2147/DMSO.S211253

Conclusions Our findings suggest that HFD-induced microvascular dysfunction precedes the decline in renal function, and could be related to antioxidant machinery defects and inflammation activation in the kidney.

High-fat diet-induced kidney alterations in rats with metabolic syndrome: endothelial dysfunction and decreased antioxidant defense

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Function Precedes - It is well-established that endothelial dysfunction precedes the onset of cardiovascular disease, therefore NOX are important molecular links between type 2 diabetes and vascular complications. [1] Our recent report showed in a rat model of renal transplantation that mitochondrial dysfunction precedes compromised proteasome function and this results in a vicious cycle of mitochondrial injury and proteasome dysfunction. [2] Background: Numerous published studies indicate that microvascular endothelial dysfunction precedes cognitive decline in Alzheimer's disease, and that preservation of a healthy cerebrovascular endothelium can be an important. [3] CONCLUSION Reduced lung function precedes and significantly predicts the future development of T2D independently of obesity, smoking and inflammation in community-dwelling middle-aged and elderly people. [4] Rods contribute crucially to human vision and their dysfunction precedes cones’ in several retinal diseases. [5] BACKGROUND AND AIMS Endothelial dysfunction precedes atherosclerosis and smoking is a well-known risk factor for the development of endothelial dysfunction. [6] Long-term hyperglycemia conditions promote endothelial dysfunction precedes to the development of multiple organ dysfunctions. [7] Here, we review compelling evidence from two lines of inquiry: one that links microvascular rarefaction with insulin-like growth factor 1 (IGF-1) deficiencies, and another which posits that vascular dysfunction precedes hypertension. [8] These findings indicate that brachial artery dysfunction precedes an inefficient functional sympatholysis. [9] However, ALS is being redefined as a distal axonopathy, in that neuromuscular junction dysfunction precedes and may even influence motoneuron loss. [10] Conclusions Our findings suggest that HFD-induced microvascular dysfunction precedes the decline in renal function, and could be related to antioxidant machinery defects and inflammation activation in the kidney. [11]