Introduction to Fluorescence Molecular

Multimodal measurements of fluorescence molecular tomography (FMT) and magnetic resonance imaging (MRI) were performed on IVD whole organ culture model using an in-house built FMT system and a high-field MRI scanner.

The intravenous injection of HFn nanoprobes enabled the imaging of tumor cells as early as two days after tumor implantation, and the triple-modality imaging techniques, namely, near-infrared fluorescence molecular imaging (NIR-FMI), magnetic resonance imaging (MRI), and photoacoustic imaging (PAI), ensured the accuracy of detection.

Fluorescence molecular tomography (FMT) is a new type of medical imaging technology that can quantitatively reconstruct the three-dimensional distribution of fluorescent probes in vivo.

Fluorescence molecular tomography (FMT), which is used to visualize the three-dimensional distribution of fluorescence probe in small animals via the reconstruction method, has become a promising imaging technique in preclinical research.

The intravenous injection of HFn nanoprobes enabled the imaging of tumor cells as early as two days after tumor implantation, and the triple-modality imaging techniques, namely, near-infrared fluorescence molecular imaging (NIR-FMI), magnetic resonance imaging (MRI), and photoacoustic imaging (PAI), ensured the accuracy of detection.

Objective: To evaluate the effect of quantitative analysis of optical signal in the near infrared fluorescence molecular navigation surgery for oral squamous cell carcinoma (OSCC).

Here we present an intravital mesoscopic fluorescence molecular tomography (henceforth IFT) approach that is capable of tracking fluorescently labeled tumor cells in a quantitative manner inside the mammary gland of living mice.

We propose a novel Time-Resolved Mesoscopic Fluorescence Molecular Tomography (TR-MFMT) system based around a supercontinuum laser across visible to NIR range and a customized Single-Photon Avalanche Diode (SPAD) array.

Herein, the in vivo two-color fluorescence molecular imaging of an important immune cell, myeloid-derived suppressor cell (MDSC), was realized by using quantum dot (QD)-based nanoprobes with non-overlap emission in the second near-infrared window (NIR-II, 1,000-1,700 nm).

For dual‐color fluorescence molecular imaging, we synthesized fluorescent, recombinant‐protein‐conjugated, NIR‐emitting quantum dots (QDs), in which the recombinant protein consists of enhanced green fluorescent protein (EGFP) and the immunoglobulin binding domain (B1) of protein G.

The wide temperature sensing range especially for 1 implies that they could act as promising ratiometric fluorescence molecular thermometers.

A novel ratiometric fluorescence molecularly imprinted sensor based on a dual-emission quantum dot hybrid was fabricated and used as an alternative analytical tool for the detection of tetracycline.

Ex vivo fluorescence molecular imaging of the surgically removed plaque specimen was performed and correlated with histopathology.

A higher adiponectin content in the STZD heart tissues was further confirmed by ex vivo fluorescence molecular tomography (FMT) imaging, immunohistochemistry and western blot analysis.

Multimodal measurements of fluorescence molecular tomography (FMT) and magnetic resonance imaging (MRI) were performed on IVD whole organ culture model using an in-house built FMT system and a high-field MRI scanner.

Fluorescence molecular tomography (FMT) is a promising technique for three-dimensional (3D) visualization of biomarkers in small animals.

头颈部肿瘤的完全切除目前仍依赖于术中视诊、触诊和冰冻病理检查。在邻近重要结构的部位实现阴性切缘通常是有困难的，而头颈部肿瘤切缘阳性的患者术后复发风险高，预后差。近红外荧光分子成像（fluorescence molecular imaging，FMI）技术是一项新的技术，可实现肿瘤的术中可视化，帮助外科医生区分肿瘤组织和正常组织，推动手术领域向前发展。在这篇综述中，我们重点讨论FMI引导手术在头颈部肿瘤治疗中的最新进展和潜在的应用价值。.

The intravenous injection of HFn nanoprobes enabled the imaging of tumor cells as early as two days after tumor implantation, and the triple-modality imaging techniques, namely, near-infrared fluorescence molecular imaging (NIR-FMI), magnetic resonance imaging (MRI), and photoacoustic imaging (PAI), ensured the accuracy of detection.

Two novel fluorescence molecular rotors DpIn and NaIn were designed and synthesized involving of indolium units linked with meta-diphenol or ortha-naphthalenediol moiety, respectively.

All the studied dyes demonstrated good fluorescence molecular rotor (FMR) properties.

The results of fluorescence molecular probe and radical trapping experiments proved that hydroxyl radical, singlet oxygen, and sulfate radical were primary reactive oxygen species in VUV/Fe2+/PMS.

Tuning the excited state properties with external stimuli will lead to versatile functional materials; a representative example is the fluorescence molecular probes, in which the singlet excited states are controlled by the external stimuli, i.

If suitable targets are available, fluorescence molecular endoscopy might be promising to improve early detection.

Secondary objectives are: (1) To identify the optimal tracer dose for imaging of PitNET tissue during transsphenoidal surgery for further development in a phase 2 fluorescence molecular endoscopy trial.

The purpose of this study is to provide a simple and reliable genetic typing approach for molecular drug susceptibility test of Mycobacterium tuberculosis, through the developing of fluorescence molecular marker of rifampicin resistance gene rpoB.

In this study, the closely linked fluorescence molecular marker PM-Xa7 of  Xa7  gene was developed on the basis of sequence difference between the resistant variety ‘IRBB7’ containing  Xa7  and other nine bacterial blight susceptible rice varieties, and combine with PARMS technology (Penta-primer amplification refractory mutation system).