Introduction to First Meta Analysis

This is the first meta-analysis on risk factors and survival of HCC; however, the degree of heterogeneity of the studies was very high for some variables and it was not possible to include in this analysis other risk factors that could affect the prognosis.

METHODS We systematically searched the Medline and Embase databases between January 2012 (the date of the first meta-analysis) and December 2020 for prospective studies examining T2D risk and baseline rice intake.

We aimed to conduct the first meta-analysis to summarize current evidence on effects of cranberry supplementation on Helicobacter pylori eradication in H.

Given the role of the HPA axis in the pathophysiology of PTSD, the aim of this study was to provide the first meta-analysis of Hydrocortisone as a potential treatment for this condition.

Thus, we conducted the first meta-analysis to get a more accurate estimation of the relationship between CTLA-4 genotype and the above end points.

Conclusions This is the first meta-analysis to find an effect of ERI on the onset of T2DM incidence.

Conclusion: This is the first meta-analysis to prove that DM is an independent risk factor of CA-AKI in patients.

Conclusions This is the first meta-analysis investigating the features of Fregoli syndrome in primary and secondary psychosis.

Conclusions This is the first meta-analysis to summarize the graded quality of evidence for all RCT interventions designed to reduce the risk of AL following esophagectomy.

Conclusion This is the first meta-analysis that shows that anemia is associated with higher risk of PD when compared with patients without anemia.

This is the first meta-analysis to look at the use virtual reality in young children undergoing vascular access procedures, providing weak to moderate evidence for its use.

We conducted the first meta-analysis on body image flexibility and its correlates.

This study achieved the first meta-analysis to determine ETSP values for upland soils in China.

Accordingly, in this study we attempt to quantify diachronic Mediterranean mobility and migration by undertaking the first meta-analysis of the burgeoning radiogenic isotope datasets now available from the Mediterranean.

To the best of our knowledge, this was the first meta-analysis assessment of the relationship between the M129V SNP of the PRNP gene and susceptibility to sporadic CJD.

Methodology/principal findings Literature related to bTB in China was retrieved from China National Knowledge Infrastructure (CNKI), PubMed, ScienceDirect, VIP Chinese Journals Database, and Wan Fang Database to build the first meta-analysis for estimating the prevalence and infection moderators of bTB in dairy cattle in China.

This is the first meta-analysis examining for the effect of EMDR comparing to various control modalities on depression with dose-response.

CONCLUSION This was the first meta-analysis that specifically compared the diagnostic accuracy of 11C-Methionine and 18F-Fluorocholine PET for parathyroid localization in patients with primary hyperparathyroidism.

CONCLUSION This first meta-analysis of human BPA concentrations highlights a widespread population exposure to BPA.

Here we perform the first meta-analysis comparing SSNM with farmers’ fertilizer practice for maize, rice and wheat using 61 published papers across 11 countries.

This is the first meta-analysis of circulating GSH-Px and SOD levels in PWE and healthy controls.

Focusing on studies employing event-related brain potential methods, which offer a direct measurement of neural activity in functionally well-characterized brain networks, we present the first meta-analysis to explore acute effects of alcohol on the human brain.

Even though tobacco-induced sleep disturbances (TISDs) have been reported in previous studies, the present article is the first meta-analysis quantitatively assessing the impact of tobacco on sleep parameters.

recently published the first meta-analysis aimed at assessing D3 shortand longterm outcomes of patients with right colon cancers [2].

SIGNIFICANCE OF THE STUDY To our knowledge, this is the first meta-analysis to estimate the global prevalence of MRSA isolated from bovine mastitis cases.

Among other analyses, the authors provide the first meta-analysis of clustering and switching on semantic fluency in patients with chronic schizophrenia, reporting that patients display significantly smaller “mean cluster sizes” compared to healthy subjects.

Conclusions This is the first meta-analysis to reveal the incidence of CAL was associated with IVIG resistance in KD patients.

This is the first meta-analysis to confirm that patients with DTC are at a high risk for developing AF, which may be attributed to a state of iatrogenic hyperthyroidism due to long-term thyrotropin suppression therapy.

Conclusions : This is the first meta-analysis show that miRNAs may be used as novel biomarkers for detecting KD, especially for distinguishing KD from other febrile diseases.

This is the first meta-analysis to report the relationship between CD109 expression and prognosis in cancer patients.

Objective: This constitutes the first meta-analysis investigating whether patients with and without comorbid personality disorders can equally benefit from psychotherapy for PTSD.

To the best of our knowledge this is the first meta-analysis in the field of metaheuristics.

The first meta-analysis included was published in March, while the last one was on the 31st of October.

CONCLUSIONS This work presents the first meta-analysis of the value of iopMRI in epilepsy surgery.

CONCLUSIONS This first meta-analysis characterizing CRS patients and comparing CRS definitions revealed a lack of consistent implementation of a CRS definition from guidelines into clinical trials, compromising the replicability of the results and their applicability in clinical practice.

The aim of this study was to performed the first meta-analysis focusing on the prognostic value of sarcopenia in patients with advanced cancer who were treated with ICIs comprehensively.

CONCLUSIONS This is the first meta-analysis to quantify the risk factors for NSCLBP in nurses.

Conclusions: This is the first meta-analysis to examine the use of opioid receptor modulators in IBS, and few adverse events were reported in the available trials.

This is the first meta-analysis to clarify the expression of PD-L1 on CTCs at baseline affects the prognosis of cancer patients.

This is the first meta-analysis to demonstrate that CME/LND3 has superior long-term survival outcomes compared to NCME/LND2, hence a strong case can be made for incorporating CME/LND3 into standard care practice.

To the best of our knowledge, this is the first meta-analysis of GWAS and GO enrichment across countries for milk production traits in Holstein cows.

INTRODUCTION To determine whether renin-angiotensin system inhibitor (RASI) prescription is associated with better survival after transcatheter aortic valve implantation (TAVI), we performed the first meta-analysis of currently available studies.

This study provides the first meta-analysis on this relationship.

Introduction: Due to the diversity of reports and on the rates of medications errors (MEs) in Saudi Arabia, we performed the first meta-analysis to determine the rate of medications errors in Saudi Arabia using meta-analysis in the hospital settings.

Conclusions This is the first meta-analysis that is a head-to-head comparison examining the performance of the novel multiplex PCR-based tests Luminex xTAG GPP and FilmArray GI panel in detecting each pathogen.

OBJECTIVE We sought to produce the first meta-analysis (of medical trainee competency improvement in nutrition counseling) informing the first cohort study of patient diet improvement through medical trainees and providers counseling patients on nutrition.

With a mandate to increase the capacity to support global mental health, this is the first meta-analysis with the aim of examining where the field stands in understanding the effectiveness of psychological interventions created for, and implemented with, children in African countries who experience stress and trauma.

To identify possible sources of this discrepancy, the present study focused on executive function demands and pre-test cognitive performance, and performed the first meta-analysis of individual participant data (IPD meta-analysis) in this area of research.

CONCLUSIONS This is the first meta-analysis quantifying the association between POD and cognitive outcomes.

CONCLUSIONS Statistical evidence for five genes was obtained in this first meta-analysis of germline mutations and PCa progression.

The current study is the first meta-analysis comparing the overall sensitivity, and specificity of newly developed ultrasensitive Plasmodium falciparum malaria RDT (Alere™ Ultra-sensitive Malaria Ag P.

To the best of our knowledge, this is the first meta-analysis conducted to gauge the efficacy and safety of dotinurad.

CONCLUSION The present study is the first meta-analysis which thoroughly reveals that adjuvant HT is a risk factor of secondary DM in primary female BC patients.

Conclusion: This is probably the first meta-analysis highlighting the importance of treating patients with T2D to a target HbA1C of 7 to 7.

Conclusion This first meta-analysis on KDSS versus KD represents a basis for future works on KDSS and opens the opportunity for future multicenter studies in the search of causal relationships between presenting elements and the eventual complications of KDSS.

CONCLUSION This first meta-analysis from a developing country revealed a high prevalence of polypharmacy and PIM use in the Ethiopian older population.

This is the first meta-analysis to determine the strength of the stress-eating relationship in healthy adults and to explore the impact of potential moderators.

As the first meta-analysis of the prospective relationships between social support and PTSD, this study synthesized the available longitudinal data (75 samples including 32,402 participants) on these two constructs with a random-effects model.

It is correct that it is the first meta-analysis performed in the field, however some years ago our team performed twice a systematic review and an update of it, respectively, analysing the role of singlesite port robotic-assisted hysterectomy [2, 3].

In this work, we performed the first meta-analysis of publicly available RNA-Seq datasets to identify differentially expressed genes in the gills under different salinity conditions.

This is the first meta-analysis to reveal the optimal therapeutic range of vancomycin trough in children.

Here, we present the first meta-analysis to quantify the general response of two major arthropod taxa, terrestrial isopods and millipedes to urbanization and to reveal the underlying mechanisms.

This is the first meta-analysis focusing on histological subtypes of CP.

This appears to be the first meta-analysis assessing the accuracy of rapid direct-to-PCR in the detection of SARS-CoV-2.

To investigate the genetic architecture of litter size, we report the first meta-analysis of genome-wide association studies (GWAS) using 522 ewes and 564,377 SNPs from six sheep breeds.

This is the first meta-analysis on the topic, systematically reviewing the most relevant available evidence, comparing RT and SRS-GK as primary treatments of BS-LGGs, focusing on survival, clinical outcome, oncological control, and complications.

ADVANCES IN KNOWLEDGE This is the first meta-analysis attempting to systemically determine the cause of heterogeneity in the diagnostic accuracy and complication rate of PTNB for subsolid pulmonary nodules.

The present work provides the first meta-analysis of this growing literature to delineate brain substrates of conditioned fear-generalization and formulate a working neural model.

CONCLUSION This was the first meta-analysis that specifically assessed the impact of refeeding syndrome on mortality.

This is the first meta-analysis to prove a positive effect of the interaction between GSTM1 null genotype and smoking status on the risk of CHD.

The first meta-analysis results for 106 cycles in five studies showed no significant differences in the live birth rate between the testicular sperm group and the ejaculated sperm group (risk ratio: 0.

The first meta-analysis by Rustagi and Njei showed a 27% decrease in pain-free participants along with a reduction in narcotic usage, concluding that AOT is clinically beneficial to use.

We aim to present the current evidence on C-IONM utility for thyroid surgery by conducting the first meta-analysis on this technique.

Conclusions and Relevance: This is the first meta-analysis proving the diagnostic utility of p53-Abs for cancer patients in predicting poorer outcomes.

STRENGTH & LIMITATIONS This is the first meta-analysis defining pooled prevalence estimates and correlates of ED and DL in KS.

We performed a meta-analysis of all existing studies investigating the association between statin use and the risk of developing cholangiocarcinoma (CCA), which to the best of our knowledge is the first meta-analysis on this issue.

To address this, we present results from the first meta-analysis of the relationship between R/S and health among sexual minorities.

To our knowledge, this is the first meta-analysis related to this topic.

Conclusions Despite several limitations, this was the first meta-analysis to focus on the treatment of post-stroke spasticity using fire needle acupuncture compared with conventional acupuncture.

In the first meta-analysis (i.

As the first meta-analysis study to systematically review this topic, we followed previous conceptual discussions to evaluate the relations between four types of identity and environmental concern, which was measured by the new environmental paradigm.

Conclusion: This is possibly the first meta-analysis conducted exclusively in patients with T2D and NAFLD which presents a strong signal that GLP1-RA, improve liver function and histology by improving glycaemia, reducie body weight and hepatic fat, which in turn reduces hepatic inflammation.

In this paper, we study such externalities and their drivers by conducting the first meta-analysis of the social returns to education literature.

Conclusion: To the best of our knowledge, this is the first meta-analysis that evaluates the relationship between the NPY rs16139 polymorphism and the risk of alcoholism.

This is the first meta-analysis of objective cognitive outcomes across multiple domains from randomized MBP studies of adults.

This is the first meta-analysis to explore the connection between the HLA-G 3' UTR + 3142C/G (rs1063320) genetic variant and the risk of HPV infection.

This is the first meta-analysis examining the effects of melatonin on plants, edible plant products, and algae, and offers a scientific and technical roadmap facilitating sustainable food and feed production through the application of exogenous melatonin.

Conclusions: To the best of our knowledge, this is the first meta-analysis to focus solely on combination assays of multiple biomarkers in HCC.

Here, we present the first meta-analysis of rtfMRI-NF for psychiatric disorders, evaluating its impact on brain and behavioral outcomes.

RESULTS A total of 15 studies involving 1,161,979 patients were eventually included in the first meta-analysis, and the pooled results indicated that female patients with breast cancer showed a significantly higher risk of developing subsequent lung cancer (SIR=1.

So, we conducted the first meta-analysis to evaluate the long-term efficacy and safety of the Dumon stent for benign tracheal stenosis.

The first meta-analysis about COVID-19 disease was published on February 26, 2020, and the number of meta-analyses has grown rapidly since then.

In this first meta-analysis to quanitfy the impacts of land-use change to bioenergy on on biodiversity and amenity,  we have demonsrated  improved farm-scale biodiversity on agricultural land but also demonstrated the lack of knowledge concerning public response to bioenergy crops which could prove crucial to the political feasibility of bioenergy policies such as BECCS.

CONCLUSION This is the first meta-analysis to compare the effects of IC-CCRT or CCRT-CCT versus CCRT alone.

It is the first meta-analysis assessing the predictive utility of the DECAF score for in-hospital mortality among patients with AECOPD.

We provide the first meta-analysis on the existence and magnitude of parochialism in cooperation among pre-adults.

This is the first meta-analysis to investigate the association between preoperative HbA1c and postoperative complications in this unique population.

The first meta-analysis concluded that preoperative anti-TNF therapy increases the occurrence of overall postoperative complications, and particularly infectious complications.

This is the first meta-analysis to provide evidence that combined physical, specifically when moderately intense, and cognitive training has the capacity to improve inhibitory control, particularly when delivered to healthy individuals and those experiencing age-related decline.

Our evidence-based study is the first meta-analysis on the efficacy of MST in anti-depressive treatment and its effect on cognitive function.