Introduction to Double Blind Trials

2 We conducted a pooled analysis from three published 6-week, fixed dose, randomized, double-blind trials to explore whether polypharmacy using low-dose SGAs plus low-dose FGAs had efficacy and safety comparable with monotherapy using therapeutic-dose SGA in the acute treatment of 270 schizophrenia patients.

METHODS We conducted two prospective, randomized, double-blind trials: one involving children and the other involving adolescents and adults.

At six months, seven double-blind trials had gaps of at least 10% in at least one PRO between arms; in four trials, these gaps favored the control arm (median difference = 11.

METHODS Twenty-one cyclists performed the following three double-blind trials: 1) ingestion of 0.

We will include randomized double-blind trials comparing magnesium (at any dose, frequency, or route of administration) with placebo using participant-reported pain assessment.

Methods Results of 2 multicenter, randomized, double-blind trials of 1510 adults with ABSSSI were pooled for this analysis.

There were two randomized, placebo-controlled, double-blind trials and populations drawn from two main cohort studies (i.

MethodsPatients aged ≥ 9 years with primary axillary hyperhidrosis were randomized 2:1 (glycopyrronium tosylate: vehicle, once daily) in the double-blind trials.

This study included 610 patients with COPD, a subset of the Intent-to-treat (ITT) populations in two phase III double-blind trials assessing the efficacy and safety of mepolizumab, METREX (NCT02105948) and METREO (NCT02105961).

All studies were designed as longitudinal investigations, 2, in particular, were of high quality, being randomized, double-blind trials (RCTs).

All studies were designed as longitudinal investigations, 2, in particular, were of high quality, being randomized, double-blind trials.

Its FDA approval was based on 2 large, randomized, double-blind trials, ZOE-50 and ZOE-70 (7, 8).

DiscussionThis trial’s pragmatic research design avoids the significant costs associated with double-blind trials whilst optimising rigour in other areas of trial delivery.

METHODS MEDLINE, Embase, CENTRAL were searched until August 2017 for randomized, double-blind trials of dual combination therapy vs.

BACKGROUND A prespecified integrated safety analysis was conducted for 3 doravirine (DOR) double-blind trials (phase 2b: P007 [NCT01632345]; phase 3: DRIVE-FORWARD [NCT02275780] and DRIVE-AHEAD [NCT02403674]).

The stimulation protocol consisted of 12 three-minute, sham-controlled, double-blind trials.

Eligible trials were randomized double-blind trials comparing lithium with placebo in patients with mood disorders who were not already on lithium before randomization in order to avoid withdrawal effects in the placebo group.

Therefore, more prospective, randomized, double-blind trials are warranted to evaluate the efficacy of adjunctive steroid therapy in treating adult bacterial meningitis in Taiwan.

Eligibility criteria Randomised double-blind trials with ≥1000 patient-years of follow-up, comparing any antihypertensive agent against placebo.

Methods: Randomized clinical double-blind trials were conducted in Dr.

SELECTION CRITERIA Randomized, controlled, double-blind trials of pharmacological interventions, of any dose and by any route, compared to placebo or any active comparator, for the treatment (not prevention) of painful sickle cell VOC in adults.

SELECTION CRITERIA We included randomised, double-blind trials of two weeks' duration or longer, comparing pregabalin (any route of administration) with placebo or another active treatment for neuropathic pain, with participant-reported pain assessment.

We searched Medline, EMBASE, and the Cochrane Library to identify all randomized controlled double-blind trials investigating biological (b) and targeted synthetic DMARDs in RA.

Eleven resistance-trained men completed 2 randomized, double-blind trials: capsaicin condition or a placebo condition.

We note that the concept of full blinding and partial blinding is different from double-blind trial, and the level of blinding is relevant in both single-blind and double-blind trials.