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10.1038/s41598-021-86802-1

Fourteen linkage disequilibrium-independent SNPs were associated with each disorder separately (p < 5 × 10–4) and in the cross-disorder meta-analysis (p < 5 × 10–8).

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10.1136/jmedgenet-2021-107953

Cross-disorder meta-analysis reveals multiple risk loci that appear pleiotropic across MG and correlated disorders.

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10.3389/fgene.2021.687687

Cross-disorder meta-analysis of OA and MD identified 56 genomic risk loci (Pmeta ≤ 5 × 10–8), which show heightened expression of the associated genes in the brain and pituitary.

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Disorder Meta Analysis

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Jul 02, 2022

What is/are Disorder Meta Analysis?

Disorder Meta Analysis - Fourteen linkage disequilibrium-independent SNPs were associated with each disorder separately (p < 5 × 10–4) and in the cross-disorder meta-analysis (p < 5 × 10–8). ^[1] Cross-disorder meta-analysis reveals multiple risk loci that appear pleiotropic across MG and correlated disorders. ^[2] Cross-disorder meta-analysis of OA and MD identified 56 genomic risk loci (Pmeta ≤ 5 × 10–8), which show heightened expression of the associated genes in the brain and pituitary. ^[3]