Introduction to Crossover Interference

What is/are Crossover Interference?

Crossover Interference - Crossover frequency varies along chromosomes and crossover interference limits the coincidence of closely spaced crossovers. ^[1] Intrinsic implications of this metric include the fact that r¯ is larger when crossovers are more evenly spaced, which suggests a selective advantage of crossover interference. ^[2] We infer that levels of crossover interference are significantly lower in honeybees compared to bumblebees, which may be one mechanism that contributes to higher recombination rates in honeybees. ^[3] Crossover interference, whereby a crossover reduces the probability of a neighboring crossover, contributes to this homogeneity. ^[4] The translocation trivalent did not differ from the normal bivalents of metacentric chromosomes for the number and distribution of recombination sites as well as for the degree of centromeric and crossover interference. ^[5] One genomic interval shapes the relationship between SC length and recombination rate, likely modulating the strength of crossover interference. ^[6] Crossover frequency varies along chromosomes and crossover interference limits the coincidence of closely spaced crossovers. ^[7] Further analyses indicate that the elevated conservation of the crossover landscape is explained by a near-subtelomeric crossover preference in both yeasts, which we find to be attributable at least in part to crossover interference. ^[8] We compare desiccation stress effects on recombination rate and crossover interference in chromosome 3 between desiccation-sensitive and desiccation-tolerant Drosophila lines. ^[9]

genetic studies yet

Simulations of relatives and identical by descent (IBD) segments are common in genetic studies, yet nearly all past efforts have utilized sex averaged genetic maps while ignoring crossover interference, thus omitting factors known to affect the breakpoints of IBD segments. ^[1] Simulations of close relatives and identical by descent (IBD) segments are common in genetic studies, yet most past efforts have utilized sex averaged genetic maps and ignored crossover interference, thus omitting features known to affect the breakpoints of IBD segments. ^[2] Simulations of close relatives and identical by descent (IBD) segments are common in genetic studies, yet most past efforts have utilized sex averaged genetic maps and ignored crossover interference, thus omitting features known to affect the breakpoints of IBD segments. ^[3]

Ignored Crossover Interference

Simulations of close relatives and identical by descent (IBD) segments are common in genetic studies, yet most past efforts have utilized sex averaged genetic maps and ignored crossover interference, thus omitting features known to affect the breakpoints of IBD segments. ^[1] Simulations of close relatives and identical by descent (IBD) segments are common in genetic studies, yet most past efforts have utilized sex averaged genetic maps and ignored crossover interference, thus omitting features known to affect the breakpoints of IBD segments. ^[2]

crossover interference limit

Crossover frequency varies along chromosomes and crossover interference limits the coincidence of closely spaced crossovers. ^[1] Crossover frequency varies along chromosomes and crossover interference limits the coincidence of closely spaced crossovers. ^[2]