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Rationally Designed Anti-CRISPR Nucleic Acid Inhibitors of CRISPR-Cas9



Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus


Crispr Rna sentence examples within Short Crispr Rna



A type III-A CRISPR-Cas system employs degradosome nucleases to ensure robust immunity



Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage


Crispr Rna sentence examples within Small Crispr Rna



Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci



Live-cell single-particle tracking photoactivated localization microscopy of Cascade-mediated DNA surveillance.




Crispr Rna sentence examples within Single Crispr Rna



CRISPR/Cas12a Multiplex Genome Editing of Saccharomyces cerevisiae and the Creation of Yeast Pixel Art.



The application of CRISPR-Cas for single species identification from environmental DNA.


Crispr Rna sentence examples within Mature Crispr Rna



Mycobacterium tuberculosis type III‐A CRISPR/Cas system crRNA and its maturation have atypical features



Endogenous CRISPR-Cas System-Based Genome Editing and Antimicrobials: Review and Prospects


Crispr Rna sentence examples within Activating Crispr Rna



Prediction and diversity of tracrRNAs from type II CRISPR-Cas systems



An Agrobacterium‐delivered CRISPR/Cas9 system for targeted mutagenesis in sorghum


Crispr Rna sentence examples within Iv Crispr Rna



Structural basis of Type IV CRISPR RNA biogenesis by a Cas6 endoribonuclease



Structural basis of Type IV CRISPR RNA biogenesis by a Cas6 endoribonuclease.


Crispr Rna sentence examples within crispr rna spacer



CRISPR-Cas molecular beacons as tool for studies of assembly of CRISPR-Cas effector complexes and their interactions with DNA.



Functionally diverse type V CRISPR-Cas systems


Crispr Rna sentence examples within crispr rna detect



Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence



Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence


Crispr Rna sentence examples within crispr rna processing



Cas3 Mediated Target DNA Recognition and Cleavage is Independent of the Composition and Architecture of Cascade Surveillance Complex



Seq2DFunc: 2-dimensional convolutional neural network on graph representation of synthetic sequences from massive-throughput assay


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10.1002/adma.201905751

Dual-Locking Nanoparticles Disrupt the PD-1/PD-L1 Pathway for Efficient Cancer Immunotherapy.


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10.1016/bs.mie.2018.10.026

CRISPR-Cas molecular beacons as tool for studies of assembly of CRISPR-Cas effector complexes and their interactions with DNA.


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10.1186/s13578-019-0298-7

CRISPR Cpf1 proteins: structure, function and implications for genome editing


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10.1124/jpet.119.257287

CRISPR/Cas System for Genome Editing: Progress and Prospects as a Therapeutic Tool


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10.1016/j.molcel.2019.02.001

Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry.


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10.1016/j.biotechadv.2018.10.013

CRISPR-Cpf1-mediated genome editing and gene regulation in human cells.


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10.1073/pnas.1909400116

Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4



A Universal Proximity CRISPR Cas12a Assay for Ultrasensitive Detection of Nucleic Acids and Proteins


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10.1016/j.cell.2018.10.052

Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference


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10.1186/s13046-019-1229-5

Efficient disruption of bcr-abl gene by CRISPR RNA-guided FokI nucleases depresses the oncogenesis of chronic myeloid leukemia cells



Activities and specificities of CRISPR/Cas9 and Cas12a nucleases for targeted mutagenesis in maize


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10.1080/15476286.2018.1495492

Defining the seed sequence of the Cas12b CRISPR-Cas effector complex


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10.1021/jacs.9b09211

Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic Acid Targets.


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10.1038/s41422-019-0151-x

Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry



Systematic analysis of Type I‐E Escherichia coli CRISPR‐Cas PAM sequences ability to promote interference and primed adaptation



Primed adaptation tolerates extensive structural and size variations of the CRISPR RNA guide in Haloarcula hispanica


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10.1038/s41586-019-1849-0

Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system



Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence


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10.1038/s41587-019-0065-7

Precise gene replacement in rice by RNA transcript-templated homologous recombination



Recent advances in structural studies of the CRISPR-Cas-mediated genome editing tools



High-throughput and all-solution phase African Swine Fever Virus (ASFV) detection using CRISPR-Cas12a and fluorescence based point-of-care system


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10.1080/15476286.2018.1493334

The ribonuclease activity of Csm6 is required for anti-plasmid immunity by Type III-A CRISPR-Cas systems


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10.1016/j.jmb.2018.06.029

Molecular Mechanisms of RNA Targeting by Cas13-containing Type VI CRISPR-Cas Systems.


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10.1089/crispr.2019.0013

RNA-Guided Recombinase-Cas9 Fusion Targets Genomic DNA Deletion and Integration.



Massively parallel CRISPRi assays reveal concealed thermodynamic determinants of dCas12a binding


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10.1016/j.molcel.2019.09.013

Programmable Inhibition and Detection of RNA Viruses Using Cas13.



Single transcript unit CRISPR 2.0 systems for robust Cas9 and Cas12a mediated plant genome editing


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10.1016/j.chom.2019.05.004

Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.



Cas3 Mediated Target DNA Recognition and Cleavage is Independent of the Composition and Architecture of Cascade Surveillance Complex


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10.1101/2019.12.22.886085

Seq2DFunc: 2-dimensional convolutional neural network on graph representation of synthetic sequences from massive-throughput assay


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10.1016/j.ymeth.2019.07.015

Approaches to Study CRISPR RNA Biogenesis and the Key Players Involved.


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10.1146/annurev-biochem-013118-111730

Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases.


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10.1093/femsle/fnz106

Cas3-stimulated runaway replication of modified ColE1 plasmids in Escherichia coli is temperature dependent.


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10.1126/science.aav7271

Functionally diverse type V CRISPR-Cas systems


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10.1016/j.celrep.2019.02.094

High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage.


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10.18063/C+.V1I3.240

Application of Clustered Regularly Interspaced Short Palindromic Repeat - Cas12a System in Cancer Research and its Structural Basis



Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence


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