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Confirmatory Trials sentence examples within Larger Confirmatory Trials



Fostamatinib for the treatment of hospitalized adults with COVD-19 A randomized trial.



Fostamatinib for the treatment of hospitalized adults with COVD-19 A randomized trial.


Confirmatory Trials sentence examples within Required Confirmatory Trials



Pharmacovigilance, drug interactions, pharmacogenetics and therapeutic drug monitoring of anticancer agents: a valuable support for clinical practice



Pharmacovigilance, drug interactions, pharmacogenetics and therapeutic drug monitoring of anticancer agents: a valuable support for clinical practice


Confirmatory Trials sentence examples within Randomized Confirmatory Trials



Precision Dosing of Targeted Therapies is Ready for Prime Time.



Precision Dosing of Targeted Therapies is Ready for Prime Time.




Confirmatory Trials sentence examples within Perform Confirmatory Trials



Response to: ‘Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study’’ by Charles



Response to: ‘Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study’’ by Charles


Confirmatory Trials sentence examples within Cancer Confirmatory Trials



Methods and Designs of Modern Breast Cancer Confirmatory Trials



Methods and Designs of Modern Breast Cancer Confirmatory Trials


Confirmatory Trials sentence examples within Controlled Confirmatory Trials



Are Supplemental Branched-Chain Amino Acids Beneficial During the Oncological Peri-Operative Period: A Systematic Review and Meta-Analysis



Are Supplemental Branched-Chain Amino Acids Beneficial During the Oncological Peri-Operative Period: A Systematic Review and Meta-Analysis


Confirmatory Trials sentence examples within Prospective Confirmatory Trials



Polymorphisms in SLC44A1 are associated with cognitive improvement in children diagnosed with fetal alcohol spectrum disorder: an exploratory study of oral choline supplementation.



Polymorphisms in SLC44A1 are associated with cognitive improvement in children diagnosed with fetal alcohol spectrum disorder: an exploratory study of oral choline supplementation.


Confirmatory Trials sentence examples within Iv Confirmatory Trials



FDA conditionally approves controversial Alzheimer’s drug despite uncertainty over effectiveness



FDA conditionally approves controversial Alzheimer’s drug despite uncertainty over effectiveness


Confirmatory Trials sentence examples within confirmatory trials published



Methods and Designs of Modern Breast Cancer Confirmatory Trials



Methods and Designs of Modern Breast Cancer Confirmatory Trials


Confirmatory Trials sentence examples within confirmatory trials failed



Pharmacovigilance, drug interactions, pharmacogenetics and therapeutic drug monitoring of anticancer agents: a valuable support for clinical practice



Pharmacovigilance, drug interactions, pharmacogenetics and therapeutic drug monitoring of anticancer agents: a valuable support for clinical practice


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10.1158/1078-0432.CCR-20-4555

Precision Dosing of Targeted Therapies is Ready for Prime Time.


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10.1158/1078-0432.CCR-20-4555

Precision Dosing of Targeted Therapies is Ready for Prime Time.



Statistical considerations in clinical trial design with event-free survival as the primary efficacy endpoint.



Statistical considerations in clinical trial design with event-free survival as the primary efficacy endpoint.


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10.1136/annrheumdis-2021-220164

Response to: ‘Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study’’ by Charles



Adaptive designs for clinical trials


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10.1136/annrheumdis-2021-220164

Response to: ‘Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study’’ by Charles



Adaptive designs for clinical trials



Assessing efficacy in important subgroups in confirmatory trials: An example using Bayesian dynamic borrowing



Assessing efficacy in important subgroups in confirmatory trials: An example using Bayesian dynamic borrowing


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10.1007/s40265-021-01512-2

Casimersen: First Approval


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10.1007/s40265-021-01512-2

Casimersen: First Approval



Methods and Designs of Modern Breast Cancer Confirmatory Trials



Methods and Designs of Modern Breast Cancer Confirmatory Trials


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10.1186/s13063-021-05160-5

Systematic review of outcome domains and instruments used in designs of clinical trials for interventions that seek to restore bilateral and binaural hearing in adults with unilateral severe to profound sensorineural hearing loss (‘single-sided deafness’)


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10.1186/s13063-021-05160-5

Systematic review of outcome domains and instruments used in designs of clinical trials for interventions that seek to restore bilateral and binaural hearing in adults with unilateral severe to profound sensorineural hearing loss (‘single-sided deafness’)


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10.1007/s00122-021-03909-9

From gene banks to farmer’s fields: using genomic selection to identify donors for a breeding program in rice to close the yield gap on smallholder farms


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10.1007/s00122-021-03909-9

From gene banks to farmer’s fields: using genomic selection to identify donors for a breeding program in rice to close the yield gap on smallholder farms


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10.1158/2159-8290.CD-ND2021-0106

Immunotherapy Withdrawals Put Spotlight on Accelerated Approval.


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10.1158/2159-8290.CD-ND2021-0106

Immunotherapy Withdrawals Put Spotlight on Accelerated Approval.



Are Supplemental Branched-Chain Amino Acids Beneficial During the Oncological Peri-Operative Period: A Systematic Review and Meta-Analysis



Are Supplemental Branched-Chain Amino Acids Beneficial During the Oncological Peri-Operative Period: A Systematic Review and Meta-Analysis



Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Glucokinase Activator PB-201 and its Effects on the Glucose Excursion Profile in Drug-Naive Chinese Patients with Type 2 Diabetes: A Randomised Controlled, Crossover Trial



Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Glucokinase Activator PB-201 and its Effects on the Glucose Excursion Profile in Drug-Naive Chinese Patients with Type 2 Diabetes: A Randomised Controlled, Crossover Trial



Polymorphisms in SLC44A1 are associated with cognitive improvement in children diagnosed with fetal alcohol spectrum disorder: an exploratory study of oral choline supplementation.



Polymorphisms in SLC44A1 are associated with cognitive improvement in children diagnosed with fetal alcohol spectrum disorder: an exploratory study of oral choline supplementation.



FDA conditionally approves controversial Alzheimer’s drug despite uncertainty over effectiveness



Fostamatinib for the treatment of hospitalized adults with COVD-19 A randomized trial.



FDA conditionally approves controversial Alzheimer’s drug despite uncertainty over effectiveness



Fostamatinib for the treatment of hospitalized adults with COVD-19 A randomized trial.


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10.36118/pharmadvances.2021.13

Pharmacovigilance, drug interactions, pharmacogenetics and therapeutic drug monitoring of anticancer agents: a valuable support for clinical practice


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10.1101/2021.06.02.21257838

Prospective comparison of Bayesian and frequentist adaptive clinical trials : The SHADOW - SHINE project


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10.36118/pharmadvances.2021.13

Pharmacovigilance, drug interactions, pharmacogenetics and therapeutic drug monitoring of anticancer agents: a valuable support for clinical practice


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10.1101/2021.06.02.21257838

Prospective comparison of Bayesian and frequentist adaptive clinical trials : The SHADOW - SHINE project


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10.1177/02698811211008567

Can pragmatic research, real-world data and digital technologies aid the development of psychedelic medicine?


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10.1177/02698811211008567

Can pragmatic research, real-world data and digital technologies aid the development of psychedelic medicine?


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10.1245/s10434-021-10847-9

Vacuum-Assisted Breast Biopsy After Neoadjuvant Systemic Treatment for Reliable Exclusion of Residual Cancer in Breast Cancer Patients


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10.1245/s10434-021-10847-9

Vacuum-Assisted Breast Biopsy After Neoadjuvant Systemic Treatment for Reliable Exclusion of Residual Cancer in Breast Cancer Patients


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10.1186/s12998-019-0253-z

Guideline implementation in the Canadian chiropractic setting: a pilot cluster randomized controlled trial and parallel study



Cardiac dysautonomia in depression – heart rate variability biofeedback as a potential add-on therapy


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10.1016/j.jpainsymman.2019.06.024

Prophylactic Fentanyl Sublingual Spray for Episodic Exertional Dyspnea in Cancer Patients: A Pilot Double-Blind Randomized Controlled Trial.


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10.1186/s13054-019-2388-7

Safety and efficacy of volume-based feeding in critically ill, mechanically ventilated adults using the ‘Protein & Energy Requirements Fed for Every Critically ill patient every Time’ (PERFECT) protocol: a before-and-after study


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10.1136/bmjopen-2018-023659

Effectiveness and safety of nicotine patches combined with e-cigarettes (with and without nicotine) for smoking cessation: study protocol for a randomised controlled trial



Randomized comparison between interscalene and costoclavicular blocks for arthroscopic shoulder surgery


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10.1016/J.JCYT.2019.03.398

Designing regulatory strategies for accelerating regenerative products innovation and patient access in Taiwan



Effects of gamma radiation on the survival of four species of thrips (Thysanoptera: Thripidae)


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10.1001/jamainternmed.2019.0462

Assessment of the Clinical Benefit of Cancer Drugs Receiving Accelerated Approval.


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10.1373/clinchem.2019.310912

Tumor-Associated Release of Prostatic Cells into the Blood after Transrectal Ultrasound-Guided Biopsy in Patients with Histologically Confirmed Prostate Cancer.



University of Pennsylvania 11th annual conference on statistical issues in clinical trials: Estimands, missing data and sensitivity analysis (afternoon panel session)



Treatment policy estimands for recurrent event data using data collected after cessation of randomised treatment.



Defining Efficacy Estimands in Clinical Trials: Examples Illustrating ICH E9(R1) Guidelines.


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10.1007/s40258-019-00527-x

Time to Review Authorisation and Funding for New Cancer Medicines in Europe? Inferences from the Case of Olaratumab


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10.1001/jamainternmed.2018.6037

Coordinating Clinical Trials to Confirm Drug Safety and Efficacy-Resolving Uncertainty.



Bayesian Phase II optimization for time-to-event data based on historical information


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10.1097/SLA.0000000000003471

Total Neoadjuvant Therapy in Rectal Cancer: A Systematic Review and Meta-analysis of Treatment Outcomes.


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10.1016/B978-0-12-816577-5.00009-0

Statistical considerations of parasiticide screening tests and confirmation trials


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10.1001/jamainternmed.2018.5705

Assessment of Pregabalin Postapproval Trials and the Suggestion of Efficacy for New Indications: A Systematic Review



Diaphragm-sparing nerve blocks for shoulder surgery, revisited



Quantitative facial expression analysis revealed the efficacy and time course of oxytocin in autism.


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10.1016/j.eururo.2018.09.005

Radiofrequency-induced Thermo-chemotherapy Effect Versus a Second Course of Bacillus Calmette-Guérin or Institutional Standard in Patients with Recurrence of Non-muscle-invasive Bladder Cancer Following Induction or Maintenance Bacillus Calmette-Guérin Therapy (HYMN): A Phase III, Open-label, Random



Intrathecal liposomal cytarabine plus systemic therapy versus systemic chemotherapy alone for newly diagnosed leptomeningeal metastasis from breast cancer.


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10.1136/esmoopen-2019-000491

Tolerability of BRAF/MEK inhibitor combinations: adverse event evaluation and management


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10.1007/s40430-019-1913-6

Thermogenesis mitigation using ultrasonic actuation during bone grinding: a hybrid approach using CEM43°C and Arrhenius model



Influencing Side-Effects to Medicinal Treatments: A Systematic Review of Brief Psychological Interventions



Pre‐marketing is a type of marketing


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10.1007/s00701-019-04082-1

How much “real world” data is needed for clinical decision-making?



Choosing Estimands in Clinical Trials: Putting the ICH E9(R1) Into Practice.



Dose Finding in the Clinical Development of 60 US Food and Drug Administration–Approved Drugs Compared With Learning vs. Confirming Recommendations



Evolution not revolution: the future of the randomised controlled trial in intensive care research


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