Introduction to Clinical Value
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Clinical Value sentence examples within present study aimed
Purpose The present study aimed to evaluate the clinical value of the combined detection of soluble T cell immunoglobulinand mucin domain molecule 3 (sTim-3) and pepsinogen (PG) in sera for gastric cancer (GC) diagnosis.
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The present study aimed to evaluate the distribution pattern and clinical value of the 21-gene RS in patients with MBC.
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Clinical Value sentence examples within receiver operating characteristic
Receiver operating characteristic (ROC) analysis in the combination of subsets and function of lymphocytes presented a superior clinical value with an area under the curve (AUC) of 0.
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The potential clinical value of DN T cells was then assessed by the receiver operating characteristic (ROC) curves.
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Clinical Value sentence examples within magnetic resonance imaging
OBJECTIVES
To evaluate the clinical value of supine magnetic resonance imaging (MRI) for tumor localization in breast cancer patients with large or multifocal tumors detected by prone MRI, scheduled for oncoplastic breast conserving surgery (OBCS).
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OBJECTIVES
To assess the clinical value of periventricular white matter hyperintensity (PWMH) found on brain magnetic resonance imaging (MRI) in patients with sudden sensorineural hearing loss (SSNHL).
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Clinical Value sentence examples within positron emission tomography
Whole-body multiparameter MRI and positron emission tomography (PET) with specific tracers, such as prostate-specific membrane antigen (PSMA), fluciclovine, fluorodeoxyglucose (FDG), and so on, has demonstrated promising clinical value for treatment response monitoring of patients with metastatic CRPC.
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2-deoxy-2-[18F]fluoro-D-glucose (FDG) positron emission tomography/computed tomography (FDG PET/CT) has an established clinical value in the diagnosis and initial staging of multiple myeloma (MM).
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Clinical Value sentence examples within contrast enhanced ultrasound
The objective was to explore the clinical value of contrast-enhanced ultrasound (CEUS) in locating the sentinel lymph node (SLN) in patients with early breast cancer.
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Objective To assess the clinical value of contrast-enhanced ultrasound (CEUS) technology in predicting axillary lymph nodes status before surgery, and to explore the feasibility of sentinel lymph nodes (SLNs) localization guided by CEUS combined with 125I implantation for breast cancer.
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Clinical Value sentence examples within non small cell
BACKGROUND
Long noncoding RNAs (LncRNA) ADAMTS9-AS2 was recognized as a novel tumor suppressor and it plays an important role in the initiation and progression of malignant behavior in human cancers, but its plasma expression and clinical value in patients with non-small cell lung cancer (NSCLC) remain unknown.
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Objective: This study aims to investigate the expression and clinical value of long non-coding RNA (lncRNA) HEIH in peripheral blood of patients with non-small cell lung cancer (NSCLC).
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Clinical Value sentence examples within acute myocardial infarction
This study was to explore the feasibility of immunofluorescence based on fluorescent nanoparticles (FNP) in the detection of acute myocardial infarction (AMI) marker Cardiac troponin I (cTnI), and analyze the clinical value of optimized rescue measures in the emergency treatment of
AMI.
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The present study investigated the clinical value of myocardial contrast-delayed enhancement (DE) with multidetector computed tomography (MDCT) without iodine re-injection immediately after primary percutaneous coronary intervention (PCI) for predicting future cardiovascular events after acute myocardial infarction (AMI).
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Clinical Value sentence examples within pancreatic ductal adenocarcinoma
In this research, by detecting the expression of KLK7 in pancreatic cancer tissues and analyzing its relationship between clinicopathological characteristics and prognosis of patients with resectable pancreatic ductal adenocarcinoma (PDAC) as well as explore its clinical value in pancreatic cancer.
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BACKGROUND
The clinical value and predictors of a favorable histological response to preoperative chemoradiotherapy (CRT) in pancreatic ductal adenocarcinoma (PDAC) remains undefined.
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Clinical Value sentence examples within single photon emission
Introduction The objective was to evaluate whether hybrid imaging combining single photon emission tomography with computed tomography (SPECT/CT) provides additional clinical value for dectection of sentinel lymph nodes (SLNs) compared with intraoperative combined mapping in uterine and cervical malignancies.
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We explored the clinical value of 99mTc-Galacto-RGD2 single-photon emission computed tomography (SPECT/CT) in patients with lung cancer, Integrin αvβ3 expression, and neovascularization in lung cancer subtypes was also addressed.
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Clinical Value sentence examples within next generation sequencing
This prospective study addressed the clinical value of a targeted-gene amplicon-based plasma next-generation sequencing (NGS) assay to detect actionable mutations in ctDNA in patients with newly diagnosed advanced lung adenocarcinoma.
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This case highlights the clinical value of up-front next-generation sequencing in metastatic pancreatic cancer and the ability of pancreatic cancer with actionable molecular variants to develop atypical sites of disease and adaptive resistance.
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Clinical Value sentence examples within squamous cell carcinoma
OBJECTIVE
To evaluate the clinical value of postreatment plasmatic levels of the squamous cell carcinoma antigen (SCC-Ag) as a survival independent prognostic factor in patients with LACC.
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Objective: The goal of this study was to confirm the clinical value of pretreatment serum squamous cell carcinoma antigen (SCC-Ag) in the administration of consolidation chemotherapy in patients with cervical cancers undergoing postoperative extended-field radiotherapy (EFRT) and concurrent chemotherapy (CCRT).
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Clinical Value sentence examples within clear cell renal
N6-methyladenosine (m6A) has been involved in diverse biological processes in cancer, but its function and clinical value in clear cell renal cell carcinoma (ccRCC) remain largely unknown.
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Background: This study aimed to explore N6-methyladenosine (m6A) methylation-related immune biomarkers and their clinical value in clear cell renal cell carcinoma (ccRCC).
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Clinical Value sentence examples within dual energy computed
OBJECTIVES
To determine the optimal kiloelectron volt of noise-optimized virtual monoenergetic images [VMI (+)] for visualization of nasopharyngeal carcinoma (NPC) and nasopharyngeal lymphoma (NPL), and to explore the clinical value of quantitative parameters derived from dual-energy computed tomography (DECT) for distinguishing the two entities.
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PURPOSE
This study assesses the clinical value of dual-energy computed tomography (DECT) in the early diagnosis of intracranial hemorrhage and evaluates the risk of hemorrhagic transformation in patients with acute ischemic stroke (AIS) after mechanical thrombectomy.
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Clinical Value sentence examples within coronary artery disease
The clinical value of positive family history of premature coronary artery disease (CAD) in risk prediction of cardiovascular diseases is controversial.
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To investigate the clinical value of acoustic cardiography in the diagnosis of coronary artery disease (CAD) and post‐percutaneous coronary intervention (PCI) early asymptomatic left ventricular systolic dysfunction.
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Clinical Value sentence examples within tumor infiltrating immune
The clinical value of the model was verified using survival analysis, clinicopathological characteristics, presence of tumor-infiltrating immune cells, and chemotherapy efficacy evaluation.
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The clinical value of the model was verified through the analysis of patient survival rates, clinicopathological characteristics, presence of tumor-infiltrating immune cells, and chemotherapy efficacy evaluation.
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Clinical Value sentence examples within metastatic colorectal cancer
In order to analyze the serum tumor markers (CEA, β2-MG) combined serum CA50, AFP predict the clinical value of liver metastatic colorectal cancer, 80 cases of colorectal cancer patients with postoperative pathologic results were divided into control group and observation group, control group of 50 cases of liver metastasis in patients, observation group of 30 cases of patients with liver metastases.
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Previous studies have linked elevated NLR to worse long-term survival outcomes among patients with metastatic colorectal cancer (mCRC), but its clinical value in the management of patients with resectable colorectal liver metastases (CRLM) remains unproven.
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Clinical Value sentence examples within sentinel lymph node
To evaluate the feasibility and clinical value of the combination of carbon nanoparticles (CNPs) and indocyanine green (ICG) for identifying sentinel lymph nodes (SLNs) in endometrial cancer.
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STUDY OBJECTIVES
To explore the technique and clinical value of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) in hysterectomy and sentinel lymph node (SLN) mapping for endometrial cancer by comparing its perioperative outcomes with those of laparoscopic staging.
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Clinical Value sentence examples within enhanced computed tomography
Background To explore the clinical value of enhanced computed tomography (enhanced CT), magnetic resonance imaging (MRI), carcinoembryonic antigen (CEA), and cancer antigen 199 (CA199) in the diagnosis of rectal cancer (RC).
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The purpose of the study was to evaluate the clinical value of quantitative liver perfusion parameters and corresponding histogram parameters derived from traditional triphasic enhanced computed tomography (CT) scans in predicting histological grade of HCC.
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Clinical Value sentence examples within acute kidney injury
PURPOSE
To investigate the clinical value of urine interleukin-18 (IL-8), neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) for the early diagnosis of acute kidney injury (AKI) in patients with ureteroscopic lithotripsy (URL) related urosepsis.
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To discuss the clinical value of detecting urinary retinol binding protein (RBP) and kidney injury molecule 1 (KIM-1) in early diagonsis of cisplatin-induced acute kidney injury.
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Clinical Value sentence examples within predict patient survival
The disease control remains heterogeneous and consequently, the ability to predict patient survival would be of great clinical value.
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Conclusions Our results delineated immune landscape and subtypes in OSCC, consolidated their clinical values as robust biomarkers to predict patient survival and therapeutic benefits and reinforced key roles of TIIs and tumor-immune interactions underlying oral tumorigenesis, ultimately facilitating development of tailed immunotherapeutic strategies.
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Clinical Value sentence examples within triple negative breast
The ROC curve was also used to evaluate the clinical value of EGFR and SMC4 in the diagnosis of triple-negative breast cancer.
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METHODS
Therefore formalin fixed paraffin embedded tissue samples from 114 triple negative breast cancer patients and blood samples from 124 healthy donors were genotyped and subsequently extensive statistical analysis was performed in order to investigate the clinical value of this polymorphism in triple negative breast cancer.
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Clinical Value sentence examples within fecal microbiota transplantation
In the context, we also speculated the promising manipulation of gut microbiota in OA management, such as exercise and fecal microbiota transplantation (FMT), highlighting the clinical values of gut microbiota.
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In recent years, fecal microbiota transplantation attracted more attention since many studies have demonstrated that fecal microbiota transplantation has great clinical value in the treatment of inflammatory bowel disease, autoimmune disease, irritable bowel syndrome, metabolic syndrome and other diseases.
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Clinical Value sentence examples within acute ischemic stroke
However, the clinical value of SII in acute ischemic stroke (AIS) patients had not been further investigated.
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Recently, this scoring system have been demonstrated to have clinical value for predicting the severity of infarction and long-term clinical outcomes in acute ischemic stroke but the evidence is not strong enough due to limited numbers and single center data.
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Clinical Value sentence examples within independent prognostic factor
1007/s00428-020-02878-6) studied the clinical value of microsatellite instability (MSI) in gastric cancer and found MSI-low (L) as independent prognostic factor with respect to disease-free but not overall survival in the setting of neoadjuvant chemotherapy.
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In addition, lncRNA CASC9 demonstrated a clinical value in predicting efficacy on patients and acted as one independent prognostic factor for PFS in patients with ACC.
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Clinical Value sentence examples within dynamic contrast enhanced
The purpose of this article is to explore the clinical value of dynamic contrast-enhanced (DCE)-MRI in distinguishing benign and malignant tongue lesions and the internal heterogeneity of a tumour.
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OBJECTIVE
To investigate the clinical value of dynamic contrast enhanced ultrasound (D-CEUS) in predicting the microvascular invasion (MVI) of hepatocellular carcinoma (HCC).
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Clinical Value sentence examples within cell lung cancer
To confirm the hypothesis and provide clinical value for the finding, we collected 18F-FDG PET images of breast cancers and non–small-cell lung cancers, where we measured the distance from the point of maximum activity to the tumor centroid, normalizing it by a surrogate of the volume.
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This study was to evaluate the clinical value of serum TUM2‐PK in early‐stage non–small cell lung cancer (NSCLC) patients.
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Clinical Value sentence examples within acute heart failure
Efficacy of lung ultrasound-guided pulmonary congestion management for patients with acute heart failure is well documented, however, more evidence is needed to establish the clinical value of pulmonary congestion detection by lung ultrasound examination in patients with chronic heart failure.
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OBJECTIVE
To investigate clinical value for the risk model of acute heart failure index (AHFI) combined with emergency heart failure mortality risk grade (EHMRG) in evaluating clinical outcomes and prognosis of patients with acute heart failure (AHF).
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Clinical Value sentence examples within chronic health evaluation
For patients admitted to the emergency medical department, rapid emergency medicine score, modified early warning score and acute physiology and chronic health evaluation II score have certain clinical value in predicting the prognosis of patients at 28 d and the value of acute physiology and chronic health evaluation II score is relatively high.
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Clinical Value sentence examples within gelsolin plasma concentration
AIM: The aim of this work is to investigate the clinical value of gelsolin plasma concentration in the diagnosis of sepsis and investigate the relationship between gelsolin plasma concentration and the severity of organ dysfunction assessed by the acute physiology and chronic health evaluation (APACHE II) and SOFA scores, and to study the mortality predictive power of gelsolin plasma concentration.
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Clinical Value sentence examples within Potential Clinical Value
circRNA expression could be associated with prognostic factors and drug responses, consolidating the potential clinical value in melanoma.
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It significantly improves on previous state-of-the-art and the achieved performance has potential clinical values considering the large multi-user variability in this challenging task.
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Clinical Value sentence examples within Great Clinical Value
This review provides additional insight into carcinogenesis and will be of great clinical value for developing novel early detection and treatment strategies for this deadly disease.
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