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Clinical Developments sentence examples within New Clinical Developments
The bibliographic documentation is analyzed and the most relevant aspects that highlight engineering and its contribution to new clinical developments are shown.
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A platform such as the Dutch Melanoma Treatment Registry, in which melanoma centers collaborate and have insight in variation in treatment patterns and outcomes between centers, results in fast implementation of new clinical developments across all Dutch melanoma centers.
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Clinical Developments sentence examples within Future Clinical Developments
Clinical Developments sentence examples within Further Clinical Developments
Further clinical developments are expected, comprising 1) combination therapies of new agents with cytotoxic chemotherapies; 2) ‘novel-novel’ combinations; 3) immune therapies, including chimeric antigen receptor T-cell therapy; and 4) predictive marker analysis.
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Further clinical developments during follow up, central precocious puberty and testicular tumor with calcification, led the diagnosis of LCCSCT, a CNC related tumor.
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Clinical Developments sentence examples within Potential Clinical Developments
In this review, we summarize the pre-clinical and clinical findings defining the characteristics of ESR1 mutant breast cancer, and highlight the potential clinical developments in this field.
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Therefore, clarifying the biological basis of interactions between NSCs and GBM cells is crucial for future potential clinical developments.
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Clinical Developments sentence examples within Recent Clinical Developments
Recent clinical developments in antitumor immunotherapy involving T-cell related therapeutics have led to a renewed interest for human leukocyte antigen class I (HLA-I) binding peptides, given their potential use as peptide vaccines.
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RECENT CLINICAL DEVELOPMENTS
Although MTC is curable by surgery only, owing to its radio- and chemoresistance, the disease will often progress only slowly, and even patients with metastases will frequently survive 10 years or longer.
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Clinical Developments sentence examples within clinical developments related
This article summarizes recent clinical developments related to mithramycin and postulates a role for the use of mithramycin, or its analog, in the treatment of platinum-resistant ovarian cancer.
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Following the development of the electrocardiograph, his theories on VF in humans were eventually accepted, but there were no clinical developments related to his pioneering resuscitation work over the following decades.
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Clinical Developments sentence examples within clinical developments regarding
The focus of this review is to summarise recent clinical developments regarding the key voltage-gated potassium (KV) family-related epilepsies, which now encompasses approximately 12 established disease-associated genes, from the KCNA-, KCNB-, KCNC-, KCND-, KCNV-, KCNQ- and KCNH-subfamilies.
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The aim of the present review was mainly to cover the clinical developments regarding the use of ibrutinib in the treatment of CLL/SLL, as well as its safety and toxicity profile.
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In this review, we present clinical experiences and preclinical developments of CED in the setting of high-grade gliomas.
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Tumor immunotherapy is currently subject of intense scientific and clinical developments.
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CONCLUSIONS
Our recent experience would lead us to believe that sPRS patients have greater morbidities and challenging clinical developments that, when properly evaluated, can be managed by MDO.
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This review article discusses these ongoing clinical developments, including biological rationale as well as preliminary toxicity and efficacy, and provides an outlook for future developments.
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We review the current experimental preclinical and clinical developments of immunotherapies in CNS lymphoma as well as the effects of targeted therapies on the brain microenvironment.
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Here, we review the latest clinical developments of exosome biotechnology for diagnostic and therapeutic purposes, including the most recent COVID‐19‐related exosome‐based clinical trials.
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OBJECTIVE
The main objective is to perform an overview of experimental and clinical developments in somatic cell therapy and tissue engineering targeting the treatment of pressure injuries.
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This review highlights the advancements in the field of mRNA-based cancer therapeutics, providing insights into key preclinical developments and the evolving clinical landscape.
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In this work the author explores some recent theoretical-clinical developments in psychoanalysis rendered necessary by a real paradigm shift in the conception of the mindbody relationship.
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Evidence has indicated that As exposure induces alterations that coincide with most of the biochemical, pathological, and clinical developments of AD.
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The bibliographic documentation is analyzed and the most relevant aspects that highlight engineering and its contribution to new clinical developments are shown.
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We examined BMI trends from one year prior to one year post surgery, rates of nutrition consults, and post-op complications defined as abnormal clinical developments such as, but not limited to, infection and delayed wound healing.
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The vesicle-dependent differences between progressive and relapsing-remitting forms of the disease are relevant for clinical developments.
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Meanwhile, applications of RWE may also be used for drug discovery and repurposing, for clinical developments and post-marketing studies.
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The special issue “Homologous Recombination Repair Deficiency (HRD): from Biology to Clinical exploitation” highlights recent progress in the field and provides an overview on scientific and clinical developments.
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A platform such as the Dutch Melanoma Treatment Registry, in which melanoma centers collaborate and have insight in variation in treatment patterns and outcomes between centers, results in fast implementation of new clinical developments across all Dutch melanoma centers.
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This could increase success rates, reduce clinical trial size, and significantly impact future clinical developments of immunomodulatory therapeutics.
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Although the participants were optimistic on the clinical developments of HD research, they emphasised the need for awareness and knowledge on a societal and practical level.
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These observations suggest that targeting the HSR- or HSPA-mediated adaptive mechanisms may be a promising strategy for further preclinical developments.
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While clinical developments have significantly improved patient prognosis, effective treatment is often obstructed by limited response rates, intrinsic or acquired resistance to therapy, and adverse events.
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This article summarizes recent clinical developments related to mithramycin and postulates a role for the use of mithramycin, or its analog, in the treatment of platinum-resistant ovarian cancer.
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It tackles recent scientific and clinical developments surrounding stem cells, exploring their enormous therapeutic potential to treat diseases, such as macular degeneration, diabetes, and Parkinson’s disease.
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OBJECTIVE
In this article, we aimed to outline the current preclinical and clinical developments of non-viral delivery systems for therapeutic transgene delivery in malignant gliomas.
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In this brief review, we discuss some of the successful preclinical developments in the field and the major challenges that are yet to be addressed.
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Furthermore, we have highlighted the insights gained from current research that are entering the preclinical evaluation and information about initial clinical developments, shaping the future for next generation cancer therapeutics.
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In this review, we discuss recent clinical developments in basic and clinical research regarding acute or chronic GVHD.
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Despite numerous clinical trials and pre-clinical developments, the treatment of glioblastoma (GB) remains a challenge.
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Evidence has indicated that As exposure induces alterations that coincide with most of the biochemical, pathological, and clinical developments of AD.
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Clinical developments over the past 30 years have altered the fundamental relationship with the Lancaster Plain communities: research has become more collaborative, and the knowledge imparted by these studies is now being harnessed to provide cutting‐edge translational medicine to the very community of vulnerable individuals who need it most.
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A variety of visual aids have been developed to help clinicians spot anomalies in the oral mucosa and in recent years, scientific and clinical developments have aided in the early detection and treatment of this disease.
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These results represent a proof of principle for further clinical developments of DMHCA delivery systems.
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SBL-105, a novel DHODH inhibitor, identified using computational and in vitro analysis, was effective controlled AML cells and needs attention for further preclinical developments.
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This review provides an overview of the current scientific data as well as new clinical developments in various fields.
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With greater insight, recent clinical developments of galectin-targeting drugs could potentially also be of benefit to the clinical management of many blinding diseases.
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NCT04869592), and the superior broad neutralization performances against SARS-CoV-2 support the mutI tri-RBD as a more promising vaccine candidate for further clinical developments.
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Recent preclinical and clinical developments and outline perspectives for the radiometals are highlighted in each section.
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In this work, a systematic analysis is being carried out depending on the factors such as compatible designs, control aspects, training modes, actuation methods, and clinical developments of the devices.
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We also discussed the most promising drugs from clinical trials and preclinical developments to date.
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Our results support further preclinical and clinical developments for the use of H5K1 in the treatment of patients in need.
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In this review, we present clinical experiences and preclinical developments of CED in the setting of high-grade gliomas.
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In view of current clinical developments of potent STAT3 and Mcl-1 inhibitors, a combination of conventional treatments with these inhibitors might thus constitute a new therapeutic strategy in CLL.
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This review will explore LAG-3 modulation as an anticancer therapy, highlighting recent clinical developments.
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Lastly, we highlight a selection of promising clinical developments in the field, including various novel strategies to increase CAR-T therapy efficacy while mitigating toxicity.
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In order to provide some help for clinical treatment, in this article, we reviewed relevant literature and new clinical developments to compare various kinds of functional digestive tract reconstruction methods after proximal gastrectomy mainly from perioperative outcomes, postoperative quality of life and survival outcomes aspects.
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Various drug candidates under different stages of pre-clinical or clinical developments give us hope for the development of COVID-19 therapeutics, but there is no approved drug so far to treat this disease.
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The following steps were followed: identification of scheduled patients, reading of clinical developments in electronic medical records, individual assessment to define whether or not appointment would remain, telephone contact to inform about unscheduling.
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In parallel to the clinical developments, there are still preclinical issues to be tackled (e.
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Conclusion: Cord blood-derived CD3+CD56+ NKT-like cells may represent a powerful tool to screen and evaluate the immunoregulatory potential of biological or chemical compounds for clinical developments and applications.
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The focus of this review is to summarise recent clinical developments regarding the key voltage-gated potassium (KV) family-related epilepsies, which now encompasses approximately 12 established disease-associated genes, from the KCNA-, KCNB-, KCNC-, KCND-, KCNV-, KCNQ- and KCNH-subfamilies.
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Here we review the biology and clinical developments that enable melanoma immunotherapy today and in the future.
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The unknown immune stimulation by nucleic acid nanoparticles (NANPs) has become one of the major impediments to a broad spectrum of clinical developments of this novel technology.
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Here, we review the recent advances in the biological activity of triptolide and its analogs, their mechanisms of actions, and their clinical developments.
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Despite significant scientific and clinical developments in research on several other viruses discovered and linked to cancer risk much later, our understanding of EBV as a carcinogen and a possible target for therapeutic interventions remains limited.
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Here we present the status quo of the PT, recent regulatory, and clinical developments as well as new perspectives for its wider application in clinical medicine.
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Herein we provide an overview of recent preclinical and clinical developments in cancer immunotherapies and discuss the perspectives for future immunotherapies in PCa.
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Further clinical developments are expected, comprising 1) combination therapies of new agents with cytotoxic chemotherapies; 2) ‘novel-novel’ combinations; 3) immune therapies, including chimeric antigen receptor T-cell therapy; and 4) predictive marker analysis.
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Herein, we provide an overview of preclinical and clinical developments of mRNA therapeutics for liver diseases.
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PURPOSE OF REVIEW
This review will provide an update on the most recent clinical developments in immuno-oncology in advanced gynecologic cancers and will also highlight ongoing studies in this field.
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