Introduction to Childbearing Potential
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Depot medroxyprogesterone acetate is an injectable hormonal contraceptive, widely used by women of childbearing potential living with HIV and/or tuberculosis.
Depot medroxyprogesterone acetate is an injectable hormonal contraceptive, widely used by women of childbearing potential living with HIV and/or tuberculosis.
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Efavirenz is recommended as a preferred first-line drug for women of childbearing potential living with human immunodeficiency virus.
Efavirenz is recommended as a preferred first-line drug for women of childbearing potential living with human immunodeficiency virus.
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10.14734/pn.2021.32.2.67
Birth data including total number of births, crude birth rate (CBR), total fertility rate (TFR), and maternal statistics including women''s first marriage age, number of women of childbearing potential, distribution of maternal age at birth, maternal age by birth order, and birth weight by maternal age were reviewed.
Birth data including total number of births, crude birth rate (CBR), total fertility rate (TFR), and maternal statistics including women''s first marriage age, number of women of childbearing potential, distribution of maternal age at birth, maternal age by birth order, and birth weight by maternal age were reviewed.
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10.1136/ijgc-2020-001740
Introduction To evaluate oncological and obstetrical outcomes of early stage cervical cancer patients who underwent conservative management to retain childbearing potential.
Introduction To evaluate oncological and obstetrical outcomes of early stage cervical cancer patients who underwent conservative management to retain childbearing potential.
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10.1080/17512433.2021.1959317
In women of childbearing potential, VPA should be avoided.
In women of childbearing potential, VPA should be avoided.
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10.1213/ANE.0000000000005465
CONCLUSIONS: Two years after designating sugammadex as antagonist of choice, physician and nurse anesthesia providers reported seldom inquiring about contraceptive use among women of childbearing potential and rarely discussing potential risk of contraceptive failure from sugammadex exposure.
CONCLUSIONS: Two years after designating sugammadex as antagonist of choice, physician and nurse anesthesia providers reported seldom inquiring about contraceptive use among women of childbearing potential and rarely discussing potential risk of contraceptive failure from sugammadex exposure.
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10.1101/2021.03.30.437698
Pharmaceuticals that are intended for use in patients of childbearing potential need to be tested for teratogenicity before marketing.
Pharmaceuticals that are intended for use in patients of childbearing potential need to be tested for teratogenicity before marketing.
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10.24875/AIDSRev.M21000042
It is recommended in international and national guidelines in a wide variety of clinical scenarios for persons living with human immunodeficiency virus (HIV) (PLWHIV), including treatment-naïve, first-line NNRTI treatment failure, simplification switch in suppressed patients, pregnancy, women with childbearing potential, adolescents and children over 6 years of age.
It is recommended in international and national guidelines in a wide variety of clinical scenarios for persons living with human immunodeficiency virus (HIV) (PLWHIV), including treatment-naïve, first-line NNRTI treatment failure, simplification switch in suppressed patients, pregnancy, women with childbearing potential, adolescents and children over 6 years of age.
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10.1016/j.yebeh.2020.107540
The final questionnaire focused on three independent sections: the decision to commence ASM in different clinical situations, the choice of initial monotherapy depending on the type of epilepsy and the patient's age/sex (including childbearing potential), and the choice of initial monotherapy depending on comorbidity.
The final questionnaire focused on three independent sections: the decision to commence ASM in different clinical situations, the choice of initial monotherapy depending on the type of epilepsy and the patient's age/sex (including childbearing potential), and the choice of initial monotherapy depending on comorbidity.
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10.1186/s13063-021-05139-2
Eligible female participants of childbearing potential and male participants with a partner of childbearing potential not willing to use highly effective contraceptive measures during the trial and within the time point specified following last trial treatment dose.
Eligible female participants of childbearing potential and male participants with a partner of childbearing potential not willing to use highly effective contraceptive measures during the trial and within the time point specified following last trial treatment dose.
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10.1016/j.reprotox.2021.05.007
Together with the safety profile in nonpregnant people, this ICH-compliant nonclinical safety data supports study of BNT162b2 in women of childbearing potential and pregnant and lactating women.
Together with the safety profile in nonpregnant people, this ICH-compliant nonclinical safety data supports study of BNT162b2 in women of childbearing potential and pregnant and lactating women.
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10.1101/2021.01.11.21249585
50% of women of childbearing potential were seropositive.
50% of women of childbearing potential were seropositive.
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10.1002/cpt.2324
Depot medroxyprogesterone acetate is an injectable hormonal contraceptive, widely used by women of childbearing potential living with HIV and/or tuberculosis.
Depot medroxyprogesterone acetate is an injectable hormonal contraceptive, widely used by women of childbearing potential living with HIV and/or tuberculosis.
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10.1016/j.yebeh.2021.107928
For example, antiseizure medications (ASMs) are among the most common teratogens prescribed to women of childbearing potential.
For example, antiseizure medications (ASMs) are among the most common teratogens prescribed to women of childbearing potential.
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10.18332/ejm/142571
At the same time, women of childbearing potential belong to a digitally literate generation comprising frequent users of digital tools, internet services, and social media, although disparities are, of course, present, with various determinants affecting the ability to access and use said tools and services.
At the same time, women of childbearing potential belong to a digitally literate generation comprising frequent users of digital tools, internet services, and social media, although disparities are, of course, present, with various determinants affecting the ability to access and use said tools and services.
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10.1080/14737175.2021.1931126
In women of childbearing potential, levetiracetam (LEV) should represent the first-choice treatment.
In women of childbearing potential, levetiracetam (LEV) should represent the first-choice treatment.
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10.1016/j.ejso.2021.01.016
Fertility-sparing treatment for International Federation of Gynaecology and Obstetrics (FIGO) Stage IA/IC CCOC seems to be an acceptable treatment option for selected premenopausal women who strongly wish to preserve their childbearing potential.
Fertility-sparing treatment for International Federation of Gynaecology and Obstetrics (FIGO) Stage IA/IC CCOC seems to be an acceptable treatment option for selected premenopausal women who strongly wish to preserve their childbearing potential.
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10.1111/dth.14931
Lack of safety data on pregnant women determines difficulty in choosing the correct biologic agent to treat psoriasis in women of childbearing potential.
Lack of safety data on pregnant women determines difficulty in choosing the correct biologic agent to treat psoriasis in women of childbearing potential.
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10.1192/bjo.2021.243
To better reflect these findings in clinical practice in 2018 the Pharmacovigilance Risk Assessment Committee recommended Sodium Valproate should not be used in pregnancy unless they have a form of epilepsy unresponsive to other anti-epileptic drugs, and all with childbearing potential should be enrolled in a pregnancy prevention programme (PPP).
To better reflect these findings in clinical practice in 2018 the Pharmacovigilance Risk Assessment Committee recommended Sodium Valproate should not be used in pregnancy unless they have a form of epilepsy unresponsive to other anti-epileptic drugs, and all with childbearing potential should be enrolled in a pregnancy prevention programme (PPP).
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10.1111/trf.16459
Ideally, all prehospital blood products would be RhD-negative to avoid potentially sensitizing females of childbearing potential to the RhD antigen, with the potential for causing hemolytic disease of the fetus and newborn (HDFN) during subsequent pregnancies.
Ideally, all prehospital blood products would be RhD-negative to avoid potentially sensitizing females of childbearing potential to the RhD antigen, with the potential for causing hemolytic disease of the fetus and newborn (HDFN) during subsequent pregnancies.
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10.1080/14740338.2021.1933429
Although >70% of the respondents identified valproate to be contraindicated in any woman of childbearing potential unless the conditions of the PPP are fulfilled, experience implementing key elements in practice varied.
Although >70% of the respondents identified valproate to be contraindicated in any woman of childbearing potential unless the conditions of the PPP are fulfilled, experience implementing key elements in practice varied.
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10.1093/ajcp/aqab061
METHODS
From 2016 to 2018, there were 102 patients (women of childbearing potential: < 50 years) at Henry Ford Hospital that had serologic D discrepant testing.
METHODS
From 2016 to 2018, there were 102 patients (women of childbearing potential: < 50 years) at Henry Ford Hospital that had serologic D discrepant testing.
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10.5507/bp.2020.063
Patients of childbearing potential with evidence of NBCCS should be informed of the increased likelihood of the disease in the offspring.
Patients of childbearing potential with evidence of NBCCS should be informed of the increased likelihood of the disease in the offspring.
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10.1111/trf.16380
Evaluation of hospital practices regarding females of childbearing potential show significant variability with some hospitals transfusing O positive, with others choosing to restrict this population to O negative LTOWB or only O negative RBC component therapy.
Evaluation of hospital practices regarding females of childbearing potential show significant variability with some hospitals transfusing O positive, with others choosing to restrict this population to O negative LTOWB or only O negative RBC component therapy.
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10.1016/S2214-109X(21)00181-9
Eligible patients were adults (aged 18-60 years) with newly diagnosed DLBCL, an Eastern Cooperative Oncology Group performance status of 0-2, a CD4 count of 100 cells per μL or higher (if HIV-positive), measurable disease by physical examination, an absolute neutrophil count of 1000 × 109 cells per L or higher, a platelet count of 100 × 109 platelets per L or higher, a serum creatinine concentration of 132·60 μmol/L or less, a total bilirubin concentration of 34·21 μmol/L or less, a negative urine pregnancy test in women of childbearing potential, and no previous cytotoxic therapy.
Eligible patients were adults (aged 18-60 years) with newly diagnosed DLBCL, an Eastern Cooperative Oncology Group performance status of 0-2, a CD4 count of 100 cells per μL or higher (if HIV-positive), measurable disease by physical examination, an absolute neutrophil count of 1000 × 109 cells per L or higher, a platelet count of 100 × 109 platelets per L or higher, a serum creatinine concentration of 132·60 μmol/L or less, a total bilirubin concentration of 34·21 μmol/L or less, a negative urine pregnancy test in women of childbearing potential, and no previous cytotoxic therapy.
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10.1186/s13063-021-05190-z
INCLUSION: Patients age ≥ 18 years at screening Patients with mild or moderate COVID-19 pneumonia, defined as Grade 3 or 4 severity by the WHO COVID-19 Ordinal Scale Patients meeting criteria: Hospitalization AND SARS-CoV2 infection (clinically suspected or laboratory confirmed) AND Radiological change consistent with COVID-19 disease CRP ≥ 30mg/L at any time point Informed consent from patient or personal or professional representative Agreement to abstain from sexual intercourse or use contraception that is >99% effective for all participants of childbearing potential for 42 days after the last dose of study drug.
INCLUSION: Patients age ≥ 18 years at screening Patients with mild or moderate COVID-19 pneumonia, defined as Grade 3 or 4 severity by the WHO COVID-19 Ordinal Scale Patients meeting criteria: Hospitalization AND SARS-CoV2 infection (clinically suspected or laboratory confirmed) AND Radiological change consistent with COVID-19 disease CRP ≥ 30mg/L at any time point Informed consent from patient or personal or professional representative Agreement to abstain from sexual intercourse or use contraception that is >99% effective for all participants of childbearing potential for 42 days after the last dose of study drug.
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10.1136/ANNRHEUMDIS-2021-EULAR.3040
5 millions and the a lot of them are women of childbearing potential.
5 millions and the a lot of them are women of childbearing potential.
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10.1159/000519144
CZP is the safest biologic therapy during pregnancy, so there is low risk in prescribing it in women with childbearing potential.
CZP is the safest biologic therapy during pregnancy, so there is low risk in prescribing it in women with childbearing potential.
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10.1111/tme.12819
CONCLUSION
All patients in the study were D negative females, in which 18 were considered by guidelines to be of childbearing potential (2-42 years old) and 2 were >50 years old.
CONCLUSION
All patients in the study were D negative females, in which 18 were considered by guidelines to be of childbearing potential (2-42 years old) and 2 were >50 years old.
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10.1007/s11695-021-05482-y
Data on demographics, pre-surgery weight, body mass index (BMI), types of bariatric surgery, weight at conception, weight gain during pregnancy, type of delivery and the health of the baby were collected and analysed to study the weight loss pattern and pregnancy outcomes in female patients of childbearing potential.
Data on demographics, pre-surgery weight, body mass index (BMI), types of bariatric surgery, weight at conception, weight gain during pregnancy, type of delivery and the health of the baby were collected and analysed to study the weight loss pattern and pregnancy outcomes in female patients of childbearing potential.
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10.2139/SSRN.3798543
Participants (Group 1, women in TSL; Group 2, non-pregnant women of childbearing potential) were randomised 1:1 via validated GSK internal software: Group 1, oxytocin 240 IU (400 μg) IH or oxytocin 10 IU (17 μg) IM immediately after delivery; Group 2, intravenous (IV) oxytocin 5 IU (8·5 μg) and oxytocin 240 IU (400 μg) IH at two separate dosing sessions in a cross-over design.
Participants (Group 1, women in TSL; Group 2, non-pregnant women of childbearing potential) were randomised 1:1 via validated GSK internal software: Group 1, oxytocin 240 IU (400 μg) IH or oxytocin 10 IU (17 μg) IM immediately after delivery; Group 2, intravenous (IV) oxytocin 5 IU (8·5 μg) and oxytocin 240 IU (400 μg) IH at two separate dosing sessions in a cross-over design.
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10.1186/s13063-021-05282-w
0%, despite treatment) (5) Unsuitable serious complications based on the assessment of either the principal investigator or the sub-investigator (6) Hemophiliac or patients with a marked hemorrhagic tendency (7) Severe diarrhea (8) Hypersensitivity to the investigational drug (9) Breastfeeding or pregnancy (10) With childbearing potential and rejecting contraceptive methods during the study period from the initial administration of the investigational drug (11) Receiving rifampicin within the previous 2 weeks (12) Participated in other clinical trials and received drugs within the previous 12 weeks (13) Undergoing treatment for HIV infection (14) History of SARS-CoV-2 vaccination or wishes to be vaccinated against SARS-CoV-2 (15) Deemed inappropriate (for miscellaneous reasons) based on the assessment of either the principal investigator or the sub-investigator Intervention and comparator Patients who meet the inclusion criteria and do not meet any of the exclusion criteria will be randomized to either the nelfinavir group or the symptomatic treatment group.
0%, despite treatment) (5) Unsuitable serious complications based on the assessment of either the principal investigator or the sub-investigator (6) Hemophiliac or patients with a marked hemorrhagic tendency (7) Severe diarrhea (8) Hypersensitivity to the investigational drug (9) Breastfeeding or pregnancy (10) With childbearing potential and rejecting contraceptive methods during the study period from the initial administration of the investigational drug (11) Receiving rifampicin within the previous 2 weeks (12) Participated in other clinical trials and received drugs within the previous 12 weeks (13) Undergoing treatment for HIV infection (14) History of SARS-CoV-2 vaccination or wishes to be vaccinated against SARS-CoV-2 (15) Deemed inappropriate (for miscellaneous reasons) based on the assessment of either the principal investigator or the sub-investigator Intervention and comparator Patients who meet the inclusion criteria and do not meet any of the exclusion criteria will be randomized to either the nelfinavir group or the symptomatic treatment group.
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10.1080/16078454.2021.1905395
OBJECTIVES
To determine the rate of RhD-alloimmunization in injured RhD-negative patients in the age range of childbearing potential who were transfused with at least one unit of RhD-positive red blood cells (RBC) or low titer group O whole blood (LTOWB).
OBJECTIVES
To determine the rate of RhD-alloimmunization in injured RhD-negative patients in the age range of childbearing potential who were transfused with at least one unit of RhD-positive red blood cells (RBC) or low titer group O whole blood (LTOWB).
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10.1007/s00405-021-06794-6
According to the statements with strong consensus otorhinolaryngologists—head and neck surgeons who are pregnant, breastfeeding, or with childbearing potential should have the opportunity to receive SARS-Cov-2 vaccination.
According to the statements with strong consensus otorhinolaryngologists—head and neck surgeons who are pregnant, breastfeeding, or with childbearing potential should have the opportunity to receive SARS-Cov-2 vaccination.
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10.1192/bjo.2021.502
Aims Recent MHRA guidelines, state that Valproate medicines must no longer be used in women or girls of childbearing potential due to its highly teratogenic effects unless a Pregnancy Prevention Programme is in place.
Aims Recent MHRA guidelines, state that Valproate medicines must no longer be used in women or girls of childbearing potential due to its highly teratogenic effects unless a Pregnancy Prevention Programme is in place.
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10.1371/journal.pone.0251552
Given the lack of data for tenofovir alafenamide (TAF) in pMTCT, rates of early viral suppression with TAF and TDF were evaluated in women of childbearing potential (WOCBP) participating in 2 randomized, double-blind, Phase 3 studies in chronic HBV.
Given the lack of data for tenofovir alafenamide (TAF) in pMTCT, rates of early viral suppression with TAF and TDF were evaluated in women of childbearing potential (WOCBP) participating in 2 randomized, double-blind, Phase 3 studies in chronic HBV.
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10.1111/bcp.14956
METHODS
Healthy men, and women of non-childbearing potential, were enrolled to receive single and multiple ascending inhaled doses of AZD8154 in parts 1 and 3 of the study, respectively, while part 2 characterised the systemic PK after a single intravenous (IV) dose.
METHODS
Healthy men, and women of non-childbearing potential, were enrolled to receive single and multiple ascending inhaled doses of AZD8154 in parts 1 and 3 of the study, respectively, while part 2 characterised the systemic PK after a single intravenous (IV) dose.
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10.1111/vox.13065
A risk assessment model for predicting the risk of haemolytic disease of the fetus and newborn (HDFN) in future pregnancies following the transfusion of Rh(D)‐positive red blood cell (RBC)‐containing products to females of childbearing potential (FCP) was developed, accounting for the age that the FCP is transfused in various countries.
A risk assessment model for predicting the risk of haemolytic disease of the fetus and newborn (HDFN) in future pregnancies following the transfusion of Rh(D)‐positive red blood cell (RBC)‐containing products to females of childbearing potential (FCP) was developed, accounting for the age that the FCP is transfused in various countries.
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10.1016/j.tranon.2021.101040
hile the expression of HERV-K in the human placenta clearly warants caution when considering HERV-K directed immunotherapies for omen of childbearing potential, we must argue that a potential imune reaction against the placenta cannot be a sufficient argument o withhold cancer treatment for those accepting not to have further hildren.
hile the expression of HERV-K in the human placenta clearly warants caution when considering HERV-K directed immunotherapies for omen of childbearing potential, we must argue that a potential imune reaction against the placenta cannot be a sufficient argument o withhold cancer treatment for those accepting not to have further hildren.
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10.1093/ECCO-JCC/JJAB073.092
Within studies in the ozanimod clinical development program, female participants of childbearing potential were required to use effective contraception while receiving and up to 3 months after discontinuing ozanimod; treatment discontinuation was required if pregnancy was confirmed.
Within studies in the ozanimod clinical development program, female participants of childbearing potential were required to use effective contraception while receiving and up to 3 months after discontinuing ozanimod; treatment discontinuation was required if pregnancy was confirmed.
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10.1007/s40278-021-92564-3
Women of childbearing potential who were diagnosed with acne and initiated a study drug within 7 days were included.
Women of childbearing potential who were diagnosed with acne and initiated a study drug within 7 days were included.
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10.1002/jmd2.12172
In four phase 2 and 3 eliglustat trials of 393 adults with GD1, women of childbearing potential were required to use contraception, have monthly pregnancy tests, and discontinue eliglustat promptly if pregnant.
In four phase 2 and 3 eliglustat trials of 393 adults with GD1, women of childbearing potential were required to use contraception, have monthly pregnancy tests, and discontinue eliglustat promptly if pregnant.
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10.21203/RS.3.RS-363121/V1
According to the statements with strong consensus Otorhinolaryngologists – Head & Neck Surgeons who are pregnant, breastfeeding or with childbearing potential should have the opportunity to receive SARS-Cov-2 vaccination.
According to the statements with strong consensus Otorhinolaryngologists – Head & Neck Surgeons who are pregnant, breastfeeding or with childbearing potential should have the opportunity to receive SARS-Cov-2 vaccination.
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10.1093/molehr/gaab015
Due to increasing prevalence of hypercholesterolemia, more women of childbearing potential are taking cholesterol-lowering medications called statins.
Due to increasing prevalence of hypercholesterolemia, more women of childbearing potential are taking cholesterol-lowering medications called statins.
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10.1002/jcph.1957
Fifteen adult male and 3 adult female (of non-childbearing potential) participants were randomized to receive MK-8507 200 mg (n = 6), MK-8507 800 mg (n = 6), or placebo (n = 6).
Fifteen adult male and 3 adult female (of non-childbearing potential) participants were randomized to receive MK-8507 200 mg (n = 6), MK-8507 800 mg (n = 6), or placebo (n = 6).
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10.1007/s40262-021-00985-4
The safety of inflammatory bowel disease medications during lactation is of significant relevance to women of childbearing potential.
The safety of inflammatory bowel disease medications during lactation is of significant relevance to women of childbearing potential.
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10.4269/ajtmh.20-1578
Human anti-Zika virus immunoglobulin (ZIKV-Ig) is being developed for prophylaxis of ZIKV in at-risk populations, including women of childbearing potential and pregnant women.
Human anti-Zika virus immunoglobulin (ZIKV-Ig) is being developed for prophylaxis of ZIKV in at-risk populations, including women of childbearing potential and pregnant women.
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10.1186/s13063-020-04964-1
Current pregnancy or lactation (women with childbearing potential should have a negative pregnancy test result at the time of study enrolment).
Current pregnancy or lactation (women with childbearing potential should have a negative pregnancy test result at the time of study enrolment).
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10.1002/cpdd.953
As women of childbearing potential may be prescribed insomnia drugs, a drug‐drug interaction study was conducted.
As women of childbearing potential may be prescribed insomnia drugs, a drug‐drug interaction study was conducted.
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10.1111/ddg.14414
Women of childbearing potential were required to use effective birth control and provide a confirmed negative blood test for pregnancy prior to treatment.
Women of childbearing potential were required to use effective birth control and provide a confirmed negative blood test for pregnancy prior to treatment.
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10.1186/s13063-021-05373-8
Women of childbearing potential will be excluded due to the teratogenic properties of VPA.
Women of childbearing potential will be excluded due to the teratogenic properties of VPA.
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10.1016/j.seizure.2020.12.005
Following recent European Medication Agency restrictions on valproate (VPA) use in girls and women of childbearing potential (WOCP), the Commission on Epilepsy and Gender of the Italian League against Epilepsy integrated current literature and legislative data in order to provide clinicians with guidance on antiseizure medication (ASM) prescription for Idiopathic Generalized Epilepsies (IGEs) in this population, avoiding VPA.
Following recent European Medication Agency restrictions on valproate (VPA) use in girls and women of childbearing potential (WOCP), the Commission on Epilepsy and Gender of the Italian League against Epilepsy integrated current literature and legislative data in order to provide clinicians with guidance on antiseizure medication (ASM) prescription for Idiopathic Generalized Epilepsies (IGEs) in this population, avoiding VPA.
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10.1017/cts.2019.99
Pregnant women, nursing mothers and women of childbearing potential not using contraception known to be highly effective.
Pregnant women, nursing mothers and women of childbearing potential not using contraception known to be highly effective.
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10.26226/morressier.58e389afd462b80292384b8f
In women of childbearing potential, 68% of patients (15/22) were taking hormonal contraceptives; in six people the diagnosis was immediately preceded by inflammation.
In women of childbearing potential, 68% of patients (15/22) were taking hormonal contraceptives; in six people the diagnosis was immediately preceded by inflammation.
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10.1007/s11739-019-02175-4
Patients on thrice-weekly hemodialysis who met the following criteria were included: (1) age above 18 years; (2) history of itch for more than 6 weeks as per the definition of chronic itch by the International Forum for the Study of Itch [3]; (3) female subjects had to be willing to use adequate contraception; (4) a negative serum pregnancy test at initial screening of female subjects with childbearing potential.
Patients on thrice-weekly hemodialysis who met the following criteria were included: (1) age above 18 years; (2) history of itch for more than 6 weeks as per the definition of chronic itch by the International Forum for the Study of Itch [3]; (3) female subjects had to be willing to use adequate contraception; (4) a negative serum pregnancy test at initial screening of female subjects with childbearing potential.
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10.1093/ofid/ofz360.2200
Background In the context of medication safety, women with HIV who are of childbearing potential represent a particular challenge given the prevalence of unplanned pregnancies.
Background In the context of medication safety, women with HIV who are of childbearing potential represent a particular challenge given the prevalence of unplanned pregnancies.
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10.1007/s40264-019-00881-8
Background Women of childbearing potential are often treated with monoclonal antibodies to control chronic and debilitating inflammatory diseases.
Background Women of childbearing potential are often treated with monoclonal antibodies to control chronic and debilitating inflammatory diseases.
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10.1213/ANE.0000000000004305
In contrast, clinical evidence guiding its use during pregnancy, in women of childbearing potential, and in lactating women, is sparse.
In contrast, clinical evidence guiding its use during pregnancy, in women of childbearing potential, and in lactating women, is sparse.
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10.1016/j.jaip.2019.08.054
RESULTS
Among females of childbearing potential, 369 of 695 responded to the survey and 322 met inclusion criteria.
RESULTS
Among females of childbearing potential, 369 of 695 responded to the survey and 322 met inclusion criteria.
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10.1080/14656566.2018.1550073
ABSTRACT Introduction: Counseling for women with epilepsy of childbearing potential surrounding pregnancy issues is of the utmost importance and should be done when antiepileptic medications are prescribed and reviewed regularly at clinic visits.
ABSTRACT Introduction: Counseling for women with epilepsy of childbearing potential surrounding pregnancy issues is of the utmost importance and should be done when antiepileptic medications are prescribed and reviewed regularly at clinic visits.
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10.1136/bmj.l4831
The World Health Organization has recommended that the HIV drug dolutegravir (DTG) be the preferred first line and second line treatment for all populations, after new evidence showed that potential risks to pregnant women and those of childbearing potential is lower than previously thought.
The World Health Organization has recommended that the HIV drug dolutegravir (DTG) be the preferred first line and second line treatment for all populations, after new evidence showed that potential risks to pregnant women and those of childbearing potential is lower than previously thought.
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10.1002/cpt.1231
A statistically significant change in rank ordering of AEDs was observed for women of childbearing potential who were prescribed monotherapy for generalized or unclassified epilepsy.
A statistically significant change in rank ordering of AEDs was observed for women of childbearing potential who were prescribed monotherapy for generalized or unclassified epilepsy.
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10.1016/b978-0-12-818550-6.00001-5
In the 1990s women of childbearing potential fought for inclusion.
In the 1990s women of childbearing potential fought for inclusion.
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10.1080/10717544.2019.1622609
As ATZ may cause harm to the fetus, use of effective contraception has to be assured in women of childbearing potential.
As ATZ may cause harm to the fetus, use of effective contraception has to be assured in women of childbearing potential.
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10.1016/S1473-3099(18)30710-2
First, current safety concerns for dolutegravir use in women of childbearing potential require alternative solutions.
First, current safety concerns for dolutegravir use in women of childbearing potential require alternative solutions.
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10.1016/j.jaad.2018.10.023
Its risk in women of childbearing potential is conflicting.
Its risk in women of childbearing potential is conflicting.
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10.1016/j.jbspin.2018.09.002
Rituximab in these indications is not less effective than cyclophosphamide and is particularly useful in patients with refractory or relapsing disease, women of childbearing potential, and patients previously treated with cyclophosphamide.
Rituximab in these indications is not less effective than cyclophosphamide and is particularly useful in patients with refractory or relapsing disease, women of childbearing potential, and patients previously treated with cyclophosphamide.
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10.1017/cts.2019.193
For women, this is the result of Food and Drug Administration (FDA) action in 1977 which restricted women with childbearing potential from participating in phase I and early phase II CTs after thousands of birth defects resulted from thalidomide usage during pregnancy.
For women, this is the result of Food and Drug Administration (FDA) action in 1977 which restricted women with childbearing potential from participating in phase I and early phase II CTs after thousands of birth defects resulted from thalidomide usage during pregnancy.
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10.1016/j.euroneuro.2019.09.007
METHODS
A panel of experts on the pharmacological treatment of BD conducted a non-systematic review of the scientific literature and clinical guidelines until March 2019, and provided specific evidence-based and experience-based clinical recommendations for VPA switching/discontinuation in BD women of childbearing potential.
METHODS
A panel of experts on the pharmacological treatment of BD conducted a non-systematic review of the scientific literature and clinical guidelines until March 2019, and provided specific evidence-based and experience-based clinical recommendations for VPA switching/discontinuation in BD women of childbearing potential.
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10.1200/jco.2019.37.27_suppl.252
252Background: Screening appropriate female patients of childbearing potential for pregnancy prior to cancer therapy is crucial, but who and when to screen is unclear.
252Background: Screening appropriate female patients of childbearing potential for pregnancy prior to cancer therapy is crucial, but who and when to screen is unclear.
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10.1016/S1474-4422(18)30495-2
Effective contraception is particularly important for women with epilepsy of childbearing potential because of antiepileptic drug-related teratogenicity and hormonal interactions; although studies reveal many women do not receive contraceptive and preconceptual counselling.
Effective contraception is particularly important for women with epilepsy of childbearing potential because of antiepileptic drug-related teratogenicity and hormonal interactions; although studies reveal many women do not receive contraceptive and preconceptual counselling.
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10.18203/2320-1770.IJRCOG20193633
Today however an increasing number of women are choosing not to undergo hysterectomy for reasons of personal identity, perceived sexual satisfaction or childbearing potential.
Today however an increasing number of women are choosing not to undergo hysterectomy for reasons of personal identity, perceived sexual satisfaction or childbearing potential.
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10.1007/s13187-018-1468-8
Saving childbearing potential after cancer treatment is of high importance to cancer survivors.
Saving childbearing potential after cancer treatment is of high importance to cancer survivors.
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10.5414/CP203483
MATERIALS AND METHODS
This was a phase I, open-label, fixed-sequence, two-period study conducted in healthy women (18 - 65 years old) of non-childbearing potential (protocol number: MK-8228 035).
MATERIALS AND METHODS
This was a phase I, open-label, fixed-sequence, two-period study conducted in healthy women (18 - 65 years old) of non-childbearing potential (protocol number: MK-8228 035).
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10.1093/milmed/usz399
6%) serving on active duty are women of childbearing potential.
6%) serving on active duty are women of childbearing potential.
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10.1136/annrheumdis-2019-eular.7108
However biologicals are frequently prescribed in patients of childbearing potential and many patients become pregnant while using these drugs.
However biologicals are frequently prescribed in patients of childbearing potential and many patients become pregnant while using these drugs.
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10.1136/archdischild-2019-316982
Objective To analyse offspring data reported in clinical trials in pregnant women with diabetes, HIV infection or hypertension (three of the most common diseases in women of childbearing potential) and either treated prior to pregnancy for these chronic diseases or diagnosed and treated during pregnancy.
Objective To analyse offspring data reported in clinical trials in pregnant women with diabetes, HIV infection or hypertension (three of the most common diseases in women of childbearing potential) and either treated prior to pregnancy for these chronic diseases or diagnosed and treated during pregnancy.
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10.1111/trf.15569
C onventional teaching and practice indicates that females of childbearing potential (FCP) whose RhD (D) type is either unknown or who are Dshould receive Dcellular blood products.
C onventional teaching and practice indicates that females of childbearing potential (FCP) whose RhD (D) type is either unknown or who are Dshould receive Dcellular blood products.
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10.1016/j.ygyno.2019.04.007
OBJECTIVE
To evaluate the long-term outcomes of young early stage cervical cancer patients wishing to preserve their childbearing potential.
OBJECTIVE
To evaluate the long-term outcomes of young early stage cervical cancer patients wishing to preserve their childbearing potential.
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10.5603/GP.2019.0010
CONCLUSIONS
A very small percentage of women with epilepsy of childbearing potential used hormonal contraception.
CONCLUSIONS
A very small percentage of women with epilepsy of childbearing potential used hormonal contraception.
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10.1038/s41398-019-0420-y
Efavirenz is recommended as a preferred first-line drug for women of childbearing potential living with human immunodeficiency virus.
Efavirenz is recommended as a preferred first-line drug for women of childbearing potential living with human immunodeficiency virus.
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10.1188/19.CJON.S1.35-41
Unique to pediatric and young adult survivors of childbearing potential are implications for post‐treatment fertility.
Unique to pediatric and young adult survivors of childbearing potential are implications for post‐treatment fertility.
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10.1002/bdr2.1579
CONCLUSIONS
Our findings reinforce that all women of childbearing potential should consume at least 400 μg FA/day to protect against NTDs.
CONCLUSIONS
Our findings reinforce that all women of childbearing potential should consume at least 400 μg FA/day to protect against NTDs.
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10.1007/s40278-019-65758-8
The multiple sclerosis medicine, fingolimod (Gilenya), is now contraindicated in pregnant women and in women of childbearing potential who are not using effective contraception, says the EMA.
The multiple sclerosis medicine, fingolimod (Gilenya), is now contraindicated in pregnant women and in women of childbearing potential who are not using effective contraception, says the EMA.
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10.17749/2077-8333.2019.11.2.110-123
According to these documents, medications containing VA should no longer be used in female patients of childbearing potential, except in cases where other treatments for epilepsy are ineffective or contraindicated.
According to these documents, medications containing VA should no longer be used in female patients of childbearing potential, except in cases where other treatments for epilepsy are ineffective or contraindicated.
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10.1001/jamadermatol.2019.1388
The rate of pregnancy for females of childbearing potential was between 0.
The rate of pregnancy for females of childbearing potential was between 0.
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10.1007/s40278-019-70592-6
"Updated guidelines from the World Health Organization in July 2019 now recommend that dolutegravir can be prescribed in all women of childbearing potential, including those planning pregnancy as well as during pregnancy, provided the woman is fully informed of the potential increased risk of NTDs (at conception and until the end of the first trimester).
"Updated guidelines from the World Health Organization in July 2019 now recommend that dolutegravir can be prescribed in all women of childbearing potential, including those planning pregnancy as well as during pregnancy, provided the woman is fully informed of the potential increased risk of NTDs (at conception and until the end of the first trimester).
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10.1007/s40290-019-00304-0
Highest knowledge (≥ 75%) was for knowing that mycophenolate is contraindicated in women of childbearing potential not using highly effective contraception (80.
Highest knowledge (≥ 75%) was for knowing that mycophenolate is contraindicated in women of childbearing potential not using highly effective contraception (80.
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10.1001/jamanetworkopen.2018.6606
Meaning The findings of this study corroborate that counseling is appropriate for the use of valproate in pregnancy and in women of childbearing potential.
Meaning The findings of this study corroborate that counseling is appropriate for the use of valproate in pregnancy and in women of childbearing potential.
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10.1111/epi.16407
The aim of our study was to investigate the relationship between VPA avoidance/switch and seizure outcome in women of childbearing potential.
The aim of our study was to investigate the relationship between VPA avoidance/switch and seizure outcome in women of childbearing potential.
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10.1007/s40263-018-00602-2
Treatment of JME in women of childbearing potential must consider multiple factors such as desire for pregnancy, use of contraception, seizure control and previously used antiepileptic drugs (AEDs).
Treatment of JME in women of childbearing potential must consider multiple factors such as desire for pregnancy, use of contraception, seizure control and previously used antiepileptic drugs (AEDs).
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10.6002/ect.MESOT2018.O42
RESULTS
Of 750 female kidney transplant recipients within childbearing potential, there were 82 pregnancies (10.
RESULTS
Of 750 female kidney transplant recipients within childbearing potential, there were 82 pregnancies (10.
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10.5114/pjp.2019.90402
In case of Sertoli Leydig cell tumors, especially in young women of childbearing potential, special attention should be paid to Anti-Mullerian hormone testing before surgery, as well as genetic diagnostics to exclude disorders of sex development.
In case of Sertoli Leydig cell tumors, especially in young women of childbearing potential, special attention should be paid to Anti-Mullerian hormone testing before surgery, as well as genetic diagnostics to exclude disorders of sex development.
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10.1097/WCO.0000000000000659
Available information now permits a more rational AED selection in women of childbearing potential, and evidence-based counseling on optimization of AED treatment before conception.
Available information now permits a more rational AED selection in women of childbearing potential, and evidence-based counseling on optimization of AED treatment before conception.
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10.1177/2042098619865413
Prior to being approved, the medicinal product will have been evaluated in a population pool containing fewer than 5,000 patients and in a predesigned environment where several factors may be lacking, such as the absence of women of childbearing potential, geriatric patients and paediatric patients.
Prior to being approved, the medicinal product will have been evaluated in a population pool containing fewer than 5,000 patients and in a predesigned environment where several factors may be lacking, such as the absence of women of childbearing potential, geriatric patients and paediatric patients.
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10.5694/mja2.50246
To avoid common adverse effects of valproate, such as weight gain, metabolic syndrome, hair loss and gastrointestinal disturbance, epileptologists have since also reduced prescribing valproate to women without childbearing potential and to men.
To avoid common adverse effects of valproate, such as weight gain, metabolic syndrome, hair loss and gastrointestinal disturbance, epileptologists have since also reduced prescribing valproate to women without childbearing potential and to men.
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10.1684/epd.2019.1105
The risks associated with use of antiepileptic drugs during pregnancy are a major concern for all women with epilepsy with childbearing potential.
The risks associated with use of antiepileptic drugs during pregnancy are a major concern for all women with epilepsy with childbearing potential.
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10.14744/epilepsi.2019.67209
Valproic acid (VPA) is one of the most frequently prescribed antiepileptic drugs for idiopathic generalized epilepsy, chronic or migraine headache, and bipolar disorder; however concerns about teratogenic effects have resulted in limited usage of the drug in women of childbearing potential.
Valproic acid (VPA) is one of the most frequently prescribed antiepileptic drugs for idiopathic generalized epilepsy, chronic or migraine headache, and bipolar disorder; however concerns about teratogenic effects have resulted in limited usage of the drug in women of childbearing potential.
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10.1007/s40290-019-00278-z
use in women of childbearing potential) and for recommendations that are not standard medical practice in Canada (e.
use in women of childbearing potential) and for recommendations that are not standard medical practice in Canada (e.
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10.1016/j.ygyno.2019.07.002
Total hysterectomy with or without bilateral salpingo-oophorectomy is the standard treatment if fertility is completed, whereas myomectomy alone can be taken into consideration in young patients who desire to preserve childbearing potential.
Total hysterectomy with or without bilateral salpingo-oophorectomy is the standard treatment if fertility is completed, whereas myomectomy alone can be taken into consideration in young patients who desire to preserve childbearing potential.
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