Introduction to Cervical Brachytherapy

What is/are Cervical Brachytherapy?

Cervical Brachytherapy - The University of Mississippi Medical Center (UMMC) has initiated an MRI-based cervical brachytherapy program and has treated 18 patients to date; our experience confirms the above findings. ^[1] Intracavitary cervical brachytherapy delivers high doses of radiation to the target tissue and a portion of these doses will also hit the rectal organs due to their close proximity. ^[2] PURPOSE/OBJECTIVE(S) Intracavitary cervical brachytherapy (BT) has transitioned from a two-dimensional non-volumetric (NV) dosimetry system to three-dimensional (3D) CT and/or MRI-based planning techniques. ^[3] Purpose To develop and validate a preliminary machine learning (ML) model aiding in the selection of intracavitary (IC) versus hybrid interstitial (IS) applicators for high-dose-rate (HDR) cervical brachytherapy. ^[4] Sub-optimal placement of both intracavitary devices and interstitial needles is a relatively common occurrence in cervical brachytherapy, which may reduce the accuracy of dose distribution and contribute to adverse toxicities. ^[5] There is a crucial unmet need for an accessible economical soft-tissue imaging modality in cervical brachytherapy. ^[6] This study compares the planned with in vivo doses measured with MOSkin and PTW 9112 rectal probe in patients undergoing CT based HDR cervical brachytherapy with Co-60 source. ^[7] Eighty-four percent agree/strongly agree that cervical brachytherapy is underutilized, and 46. ^[8] In cervical brachytherapy the radiation dose is delivered using an applicator. ^[9] CONCLUSIONS MRI-to-CT deformable image registration using a cervix-controlling region of interest can aid clinical target delineation in cervical brachytherapy and potentially improve brachytherapy implant quality and clinical workflow. ^[10] Our patient, a 32-year old woman with a 5 cm FIGO IIB cervical cancer, had a uterus Didelphys and was therefore not suitable for intracervical brachytherapy. ^[11]

Intracavitary Cervical Brachytherapy

Intracavitary cervical brachytherapy delivers high doses of radiation to the target tissue and a portion of these doses will also hit the rectal organs due to their close proximity. ^[1] PURPOSE/OBJECTIVE(S) Intracavitary cervical brachytherapy (BT) has transitioned from a two-dimensional non-volumetric (NV) dosimetry system to three-dimensional (3D) CT and/or MRI-based planning techniques. ^[2]