Introduction to Cancer Cohort
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Cancer Cohort sentence examples within small cell lung
Cancer Cohort sentence examples within prospective cohort study
METHODS
In this nationwide, population-based, prospective cohort study, we analysed data from the China Cardiometabolic Disease and Cancer Cohort Study, which recruited adults aged 40 years or older during 2011-12 (baseline) and invited participants to attend follow-up visits in 2014-16.
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Design, Setting, and Participants
The China Cardiometabolic Disease and Cancer Cohort Study was a nationwide, population-based, prospective cohort study of 20 communities from various geographic regions in China.
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Cancer Cohort sentence examples within predicted overall survival
The signature successfully predicted overall survival rates in 6 cancer cohorts (n = 3050): bladder (P = 0.
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ResultsThe 45-gene signature predicted overall survival in three liver cancer cohorts: hazard ratio (HR) = 1.
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Cancer Cohort sentence examples within non small cell
The number of patients achieving an objective response was three (7%; 95% CI 1·5-19·9) of 41 in the gastric or gastro-oesophageal junction adenocarcinoma cohort, eight (30%; 13·8-50·2) of 27 in the non-small-cell lung cancer cohort, and three (13%, 2·7-32·4) in the urothelial carcinoma cohort.
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We evaluated the use and survival effect of preoperative invasive mediastinal nodal staging in a population-based non-small cell lung cancer cohort.
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Cancer Cohort sentence examples within log rank test
Survival rates and curves in a breast cancer cohort of 109 patients were determined by the Kaplan-Meier method and the comparison of survival differences was evaluated by using the log-rank test.
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The Kaplan–Meier method and log-rank test were performed based on the expression level of TP73 in a cervical cancer cohort from the TCGA database, and showed that TP73 expression was positively correlated with overall survival time in cervical cancer patients.
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Cancer Cohort sentence examples within triple negative breast
Higher gene expression score of ESM-1 gene was strongly associated with worse overall survival (OS) in the triple-negative breast cancer (TNBC) and hormonal receptor (HR)-positive/HER2-negative subtype in METABRIC cohort, HER2+ subtype in TCGA-BRCA and SCAN-B breast cancer cohorts.
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In a basket design phase I/II study, sacituzumab govitecan demonstrated promising single agent therapeutic activity in multiple cancer cohorts, leading to accelerated approval by the United States FDA of sacituzumab govitecan-hziy (TRODELVY) for the treatment of patients with metastatic triple-negative breast cancer who had received at least 2 prior therapies in the metastatic setting.
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Cancer Cohort sentence examples within Breast Cancer Cohort
In this study, we apply quantitative automated image processing and computational methods to profile the subcellular distribution of the multi-functional transcriptional regulator, Kaiso ( ZBTB33 ), in the tumors of a large racially diverse breast cancer cohort from a designated health disparities region in the United States.
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php?p=background) which showed that that an increased expression of SIKs was associated with good prognosis in the breast cancer cohort (p Citation Format: Ling Xin, Chang Liu, Yinhua Liu, Robert E.
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Cancer Cohort sentence examples within Lung Cancer Cohort
8% of patients in the lung cancer cohort that had targeted next-generation gene panel analysis demonstrated presence of at least one mutation.
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Cancer Cohort sentence examples within Prostate Cancer Cohort
Cancer Cohort sentence examples within Colorectal Cancer Cohort
Methods In April 2020, 4984 patients included in the nationwide Prospective Dutch Colorectal Cancer cohort were invited to complete a COVID-19–specific questionnaire, together with the validated European Organisation for Research and Treatment of Cancer Core Quality of Life Questionnaire (QLQ-C30), De Jong Gierveld, and Hospital Anxiety and Depression Scale.
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In TCGA colorectal cancer cohort, the median PD-L1 expression was significantly higher in the LOF group (1.
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Cancer Cohort sentence examples within Ovarian Cancer Cohort
Two DDR gene expression clusters correlating with treatment response were identified, with PARP10 identified as a novel marker of platinum response, which was confirmed in The Cancer Genome Atlas (TCGA) ovarian cancer cohort.
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Cancer Cohort sentence examples within Gastric Cancer Cohort
EPLIN transcript expression, in conjunction with patient clinicopathological information and responsiveness to neoadjuvant chemotherapy (NAC), was explored in two gastric cancer cohorts collected from the Beijing Cancer Hospital.
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High treatment heterogeneity in the gastric cancer cohort and lack of a homogeneous quartile for comparisons limited the ability to evaluate HCRU by different levels of treatment variability.
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Cancer Cohort sentence examples within Cervical Cancer Cohort
Methods: From the cervical cancer cohorts of two tertiary hospitals, patients with 2009 FIGO stage IB-IIA who underwent primary RH between 2010 and 2018 were identified.
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4% for the cervical cancer cohort, suggesting a subset of patients may harbor mutations which that are targetable.
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Cancer Cohort sentence examples within Pancreatic Cancer Cohort
Methods To estimate survival after PD, a nomogram was developed using the Tongji Pancreatic cancer cohort comprising 355 PHDAC patients who underwent PD.
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METHODS
We developed a neural network that quantified the tissue components at the L3 vertebral body level using data from the Liver Tumor Challenge (LiTS) and a pancreatic cancer cohort.
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Cancer Cohort sentence examples within Colon Cancer Cohort
Methods Analysis of CMTM6 mRNA levels, gene ontology enrichment analysis and single-sample gene set enrichment analysis were performed in a The Cancer Genome Atlas colon cancer cohort.
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Methods Stromal scores were calculated based on the expression profiles of a colon cancer cohort from TCGA database applying the ESTIMATE algorithm.
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Cancer Cohort sentence examples within Bladder Cancer Cohort
This newly identified bladder hypoxic matrisome signature will be evaluated further in plasma samples from a bladder cancer cohort as a potential biomarker for patient stratification to identify those likely to benefit from hypoxia-modifying treatments.
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Methods The published single-cell RNA sequencing data of 49,869 bladder cancer cells and 15,827 normal bladder mucosa cells and The Cancer Genome Atlas (TCGA) bladder cancer cohort data were used to explore the mRNA expression of SLC16A3 in bladder cancer.
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Cancer Cohort sentence examples within Liver Cancer Cohort
The “estimate” package and the CIBERSORT algorithm were used to evaluate tumor purity and the proportion of CD8+ T lymphocytes in the liver cancer cohort.
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Results: Raman spectral signatures obtained by Raman spectroscopy of liver tissue samples of healthy normal liver versus liver cancer cohorts exhibited complete discrimination of healthy ones from the affected diseased counterparts with high accuracy classification.
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Cancer Cohort sentence examples within Large Cancer Cohort
This study aimed to investigate and compare the prevalence of malnutrition using the GLIM, European Society for Clinical Nutrition and Metabolism (ESPEN) and International Statistical Classification of Diseases version 10 (ICD-10) criteria; compare the level of agreement between these criteria; and identify the predictive validity of each set of criteria with respect to 30-day outcomes in a large cancer cohort.
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The variant frequencies in the sequence units were highly reproducible between two large cancer cohorts.
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Cancer Cohort sentence examples within Three Cancer Cohort
Multivariable Cox regression models were used to study the association between HF and dementia compared to each of three cancer cohorts.
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The increased TMB, antitumor immune activity, and PD-L1 expression indicated a favorable response to immune checkpoint inhibitors (ICIs) in EP300-mutated cancers, as evident in three cancer cohorts treated with ICIs.
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Cancer Cohort sentence examples within Multiple Cancer Cohort
In a basket design phase I/II study, sacituzumab govitecan demonstrated promising single agent therapeutic activity in multiple cancer cohorts, leading to accelerated approval by the United States FDA of sacituzumab govitecan-hziy (TRODELVY) for the treatment of patients with metastatic triple-negative breast cancer who had received at least 2 prior therapies in the metastatic setting.
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Interestingly, the top 3 identified genes; Microtubule-associated protein tau (MAPT), Toll-like receptor 9 (TLR9) and Tyrosyl-DNA phosphodiesterase 1 (TDP1) were observed to be over expressed in multiple cancer cohorts and were associated with poor prognoses of the patients.
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Cancer Cohort sentence examples within Thyroid Cancer Cohort
Cancer Cohort sentence examples within Multicenter Cancer Cohort
A total of 11,632 patients without self-reported diabetes mellitus and colorectal polyps’ history were identified in the Korean Multicenter Cancer Cohort (1993–2005).
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Methods: We conducted a nested case–control study consisting of 238 gastric cancer cases and 238 matched controls within the Korean Multicenter Cancer Cohort.
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Cancer Cohort sentence examples within Uterine Cancer Cohort
Here we present data from the ovarian and uterine cancer cohorts of the Phase I atezolizumab monotherapy study (PCD4989g).
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Methods: The clinicopathologic information and RNA-Seq expression data of DNMT3A/3B of 544 endometrial cancers were derived from The Cancer Genome Atlas (TCGA) uterine cancer cohort in May 2018.
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Cancer Cohort sentence examples within Urothelial Cancer Cohort
We used Ancer, an immunoinformatic CD8, CD4, and regulatory T cell neoepitope screening system, to perform an advanced neoantigen analysis of genomic data derived from the urothelial cancer cohort of The Cancer Genome Atlas.
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Methods A pooled analysis based on 10 randomized controlled trials was conducted to evaluate the clinical benefit of atezolizumab versus standard therapy in patients stratified by liver metastatic status, followed by biomarker-based individual analyses of the non-small cell lung cancer (NSCLC) cohort (OAK and POPLAR studies) and urothelial cancer cohort (IMvigor210 study).
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Cancer Cohort sentence examples within Five Cancer Cohort
Cancer Cohort sentence examples within Human Cancer Cohort
Cancer Cohort sentence examples within Endometrial Cancer Cohort
Cancer Cohort sentence examples within Adult Cancer Cohort
Background High-quality evidence supports the integration of exercise to mitigate treatment-related side effects in a wide range of paediatric and adult cancer cohorts.
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The PCAWG adult cancer cohort yielded different significant SNV-expression associations from the CBTTC pediatric brain tumor cohort.
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Cancer Cohort sentence examples within Tcga Cancer Cohort
By modeling properties of cell surface proteins from TCGA datasets we seek to identify optimal targets across all TCGA cancer cohorts that when used in CAB-CAR-T therapies will provide the greatest number of treatment options for patients across all cancer malignancies.
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Bacterial diversity correlates with tumor stage and survival in stomach and lung TCGA cancer cohorts [abstract].
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Cancer Cohort sentence examples within Childhood Cancer Cohort
Survivors were eligible if they received a diagnosis of cancer according to the 12 main groups of the International Classification of Childhood Cancer, 3rd edition, or Langerhans cell histiocytosis; were aged ≤18 years at the time of diagnosis; were residents of the respective country at the time of diagnosis; had survived ≥5 years after cancer diagnosis; were aged ≥18 years at the time of the questionnaire survey; and did not refuse to registration in the national or local childhood cancer cohort.
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We prospectively evaluated parental occupational exposures and risk of childhood leukemia and central nervous system (CNS) tumors in the International Childhood Cancer Cohort Consortium.
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Cancer Cohort sentence examples within Rectal Cancer Cohort