Introduction to Blind Randomized

What is/are Blind Randomized?

Blind Randomized - MATERIALS AND METHODS A prospective, double-blind randomized controlled trial was performed in 51 patients scheduled to undergo same-day bilateral TKAs. ^[1] Additionally, a triple-blind randomized controlled trial was conducted with 41 hospitalized patients who tested positive for COVID-19. ^[2] METHODS In this double-blind randomized controlled trial, women who sustained obstetric anal sphincter injuries were randomized to receive self-administered vaginal electrical stimulation using a commercial device or sham therapy with an identical device. ^[3] Strength of Recommendation: There is 'Fair' to 'Good' evidence from 2 level 1b single-blind randomized control studies and 1 level 2b pre-post test control design study supporting the inclusion of exercise programs targeting scapular kinematics and stability to decrease chronic neck pain severity. ^[4] Methods This single-blind randomized clinical trial was performed over the period between February 2019 and March 2020 in the neonatal intensive care unit of Babol Rouhani Hospital, Iran. ^[5] This is a prospective, interventional, comparative, double-blind randomized control study which was done at a tertiary care center to compare outcomes of conventional and carved conchal cartilage (vertical strut) type III Tympanoplasty in terms of graft uptake and hearing gain. ^[6] METHODS We conducted a double-blind randomized clinical trial to evaluate the effects of probiotics administered to patients with mild acute pancreatitis at a tertiary medical center. ^[7] Methods: This study was a single-blind randomized controlled trial on fixed orthodontic appliance candidates (n = 90), assigned into a control group (n = 30) and two different study groups (n = 30 each). ^[8] Design Single‐site double‐blind randomized controlled superiority trial comparing CBD with placebo. ^[9] Methodology: A double-blind randomized cohort study was carried out in three districts of Luwuk, South Luwuk, and North Luwuk, Banggai Regency with a total sample of 19 pregnant women given MMN supplementation and IFA supplementation. ^[10] In order to shed light on this topic, 40 young Italian adults were involved in a single-blind randomized counterbalanced crossover experiment, in which we asked them to report on a series of visuo-analogue scales their physiological (i. ^[11] Double-blind randomized controlled studies are necessary to help elucidate the effects of rTMS in the different symptoms in BPD and establish efficacy and the best cortical targets and stimulation protocols. ^[12] Danilo Arnone and colleagues conducted a review of double-blind randomized controlled studies investigating the use of onabotulinumtoxinA compared to placebo in the treatment of major depression. ^[13] Method/design In a single-blind randomized controlled trial (RCT), 80 female opioid and/or methamphetamine users will be recruited from an addiction recovery program providing an alternative to incarceration for women with substance use-related offenses. ^[14] This double-blind randomized clinical trial was conducted on 56 people with multiple sclerosis relapse who had undergone methylprednisolone for 5 days. ^[15] Methods: The study is designed as a double-blind randomized control trial. ^[16] Premedication with gabapentin for laryngoscopy: a double-blind randomized control trial in hypertensive patients. ^[17] We did a secondary analysis of a double-blind randomized trial of pneumococcal conjugate vaccine (PCV) to examine its impact on human coronavirus (CoV) infections before the pandemic. ^[18] Methods: This is a double-blind randomized multicenter study in 36 centers in the U. ^[19] Methods We conducted a single-blind randomized controlled trial among 250 dyads recruited from Baltimore-Washington DC (2012–2016) with a dementia diagnosis and clinically significant agitation/aggression. ^[20] In a phase 3 double-blind randomized trial, eculizumab, a humanized monoclonal antibody that inhibits C5, the terminal complement protein, led to lower risk of relapse compared to placebo. ^[21] STUDY DESIGN Double-blind randomized controlled trial. ^[22] Methods In this double-blind randomized controlled trial, 24 healthy, young men ingested 30 g specifically produced, intrinsically l-[1-13C]-phenylalanine and l-[1-13C]-leucine labeled lesser mealworm– or milk-derived protein after a unilateral bout of resistance-type exercise. ^[23] In this prospective double-blind randomized control trial study, we evaluated the efficacy of the ondansetron, a serotonin receptor antagonist, on the incidence of spinal anesthesia-induced shivering, hypotension, nausea, vomiting and other possible complications in elective caesarean sections. ^[24] METHODS We conducted a double-blind randomized clinical trial. ^[25] Methods A double-blind randomized clinical trial was conducted on 40 patients aged 40 - 70 years under spinal anesthesia candidate for total knee arthroplasty in Golestan hospital, Ahwaz, Iran, in 2017-2018. ^[26] With a robust double‐blind randomized controlled protocol to investigate the efficacy, these trials should provide significant and definitive results. ^[27] Methods: A single-blind randomized controlled experimental study was conducted with a total of 60 postpartum women in the reflexology application (n = 30) and control groups (n = 30). ^[28] To test the developed model, a double-blind randomized study was performed. ^[29] We evaluated the efficacy, tolerability and safety of double-blind randomized controlled trials involving only adult participants comparing combination therapy (CT: ≥ 2 drugs) to placebo and/or at least one other comparator with NP indication. ^[30] LEVEL OF EVIDENCE I, Bayesian network meta-analysis of double-blind randomized clinical trials. ^[31] Purpose Two previous independent double-blind randomized studies demonstrated that thermal neuromodulation using high temperature pulsed heat reduced pain in subjects with chronic low back pain. ^[32] METHODS A 2-arm, single-blind randomized controlled trial was employed to estimate the effects of the intervention on smoking cessation in comparison to treatment as usual. ^[33] We used the explanatory sequential design, with a pilot two-group single-blind randomized controlled trial (N = 50) followed by in-depth interviews with all trial participants. ^[34] To investigate this, we administered 20 mg escitalopram or placebo for 1-week to 60 healthy female participants undergoing concurrent functional magnetic resonance imaging and sequence motor training in a double-blind randomized controlled design. ^[35] 8 g·h-1 casein hydrolysate or placebo-water during exercise (60-80 minutes) comprising an incremental test to exhaustion, steady-state exercise (70% Vmax or 60% peak power output, 87 ± 4% HRmax), and 20-minute time trial (TT) in a double-blind randomized crossover design, with p < 0. ^[36] A triple-blind randomized controlled trial was designed to evaluate the effects of these medications on the COVID-19 progression. ^[37] Methods In this single-blind randomized clinical trial, thirty-two female athletes with PFP (mean age 26. ^[38] METHODS In a single-blind randomized clinical trial, 148 vital teeth with an indication for conventional endodontic therapy for prosthetic purposes were treated by five specialists following a pre-established protocol. ^[39] METHODS A 2-arm, single-blind randomized controlled trial was employed to estimate the effects of the intervention on smoking cessation in comparison to treatment as usual. ^[40] METHODS This study was a double-blind randomized controlled trial. ^[41] Method: This was a double-blind randomized clinical trial. ^[42] Materials and Methods A single-blind randomized control trial involving 78 individuals with sub-acute and chronic stroke. ^[43] Methods This was a single-blind randomized controlled trial. ^[44] Methods A single-blind randomized controlled trial with baseline and follow-up assessments was conducted at two community centers in Singapore. ^[45] A single-blind randomized controlled trial was used to compare the effects of CSE and STE on balance, pain, and trunk muscle activity patterns in 38 CLBP patients with CLI. ^[46] Methods: This double-blind randomized clinical trial was performed from February 20, to June 22, 2019, on 72 older adults with KO referring to the office of a physician in Kashan, Iran. ^[47] METHODS A cost-utility analysis at 28 days was carried out using data from the French COPOUSEP multicenter, double-blind randomized controlled non-inferiority trial and the statutory health insurance reimbursement database. ^[48] Methods A single-blind randomized clinical trial was conducted on 98 patients in Besat Educational Hospital, Hamadan, Iran. ^[49] In this secondary analysis of data from a double‐blind randomized controlled trial (clinicaltrials. ^[50]

controlled clinical trial

MethodsIn this double-blind randomized placebo controlled clinical trial, 81 mild to moderate hospitalized COVID-19 patients with inclusion criteria were randomly divided to treatment (n=42) group to receive melatonin tablet 3 mg, three times daily for 2 weeks or placebo (n=39) group. ^[1] METHODS: Double-blind randomized controlled clinical trial was conducted in 50 HIV patients who took regular ARV therapy. ^[2] Methods In a double-blind randomized controlled clinical trial study, 204 patients undergoing elective cesarean section with class 1 and 2 anesthesia (ASA) were enrolled. ^[3] This double-blind randomized controlled clinical trial aimed to evaluate the effect of a violet light emission diode (LED) (405nm) system, used in-office, on tooth whitening, sensitivity, use of medication after whitening and quality of life. ^[4] Patients and methods This double-blind randomized controlled clinical trial with two parallel arms will be conducted between January 2021 and July 2022. ^[5] Methods: This single blind randomized controlled clinical trial study was conducted on ShahidDastgheib Health center in Yasuj, from May to September 2016. ^[6] Large double-blind randomized placebo-controlled clinical trials (DBRPCTs) are considered to be the standard for demonstrating efficacy and safety for common diseases. ^[7] To determine the benefits of vitamin D supplementation in pregnancy would require further evaluation through large, multicenter double-blind randomized controlled clinical trials, with a focus on specific adverse pregnancy outcomes. ^[8] METHODS This double-blind randomized controlled clinical trial was conducted in 50 patients with ischemic HF. ^[9] A split-mouth single-blind randomized-controlled clinical trial study was designed to investigate the effect of local and systemic vitamin C administration on extraction wound healing. ^[10] “Pneumatic dilation for persistent dysphagia after ant reflux surgery, a multicentre single-blind randomized sham-controlled clinical trial” was critically reviewed by our expert Dr. ^[11] Methods: This single blind randomized controlled clinical trial was conducted on the patients with MS in April-June 2020, Kashan, Iran. ^[12] Materials and Methods: This single-blind randomized controlled clinical trial was conducted on 120 women who were referred to Hamadan health centers in 2019. ^[13] Methods: In this single-blind randomized controlled clinical trial, 54 old individuals in Shiraz nursing homes during November 2018-March 2019 were selected randomly and then allocated to three groups of 18, based on block randomization. ^[14] This single-blind randomized controlled clinical trial was conducted on 100 retired older adults. ^[15]

placebo controlled trial

The CATCH study is a phase IIB double-blind randomized placebo-controlled trial. ^[1] In an investigator-initiated double-blind randomized placebo-controlled trial the effect of 18 weeks of treatment with liraglutide on diastolic function was assessed in type 2 diabetes patients and echocardiographic signs of diastolic dysfunction (echo-Doppler determined E/e'≥9 or/and lateral e'≤10 cm/sec). ^[2] Materials and Methods: This double-blind randomized placebo-controlled trial in four month was conducted on 120 angiography candidates in Valiasr hospital, Birjand, Iran. ^[3] Experimental Design: In a double-blind randomized placebo-controlled trial performed in the Amsterdam University Medical Center, we assigned 24 cachectic patients with metastatic HER2-negative gastroesophageal cancer to either allogenic FMT (healthy obese donor) or autologous FMT, prior to palliative chemotherapy (capecitabine and oxaliplatin). ^[4] The recent double-blind randomized placebo-controlled trial (DBRPCT) reported that adjunctive melatonin administration was not superior to placebo in improving the mania scale scores of patients who received mood stabilizers or antipsychotics. ^[5] Methods: This study was a single-blind randomized placebo-controlled trial. ^[6] OBJECTIVE The journal received a request to retract a paper reporting the results of a triple-blind randomized placebo-controlled trial. ^[7] Methods: A double-blind randomized placebo-controlled trial with two parallel groups was conducted in women scheduled to undergo vaginal delivery at the Maternity Teaching Hospital, Erbil City, Kurdistan region, Iraq. ^[8] Materials and Methods: A multi-center, double-blind randomized, placebo controlled, trial was conducted at three centers of Central Council for Research in Homoeopathy. ^[9] MATERIALS AND METHODS In a double-blind randomized parallel-arm placebo-controlled trial, 40 stage III/IV periodontitis patients received steps 1 and 2 of periodontal treatment in two sessions within 7 days. ^[10] We performed a 12-wk double-blind randomized placebo-controlled trial in patients with severe obesity and MS recruited from Edmonton’s Bariatric Clinic from 2018 to 2019. ^[11] Here we outline the protocol for a double-blind randomized placebo-controlled trial evaluating the efficacy of adjunctive mangosteen pericarp (1,000 mg/day), compared to placebo, in the treatment of schizophrenia. ^[12] Methods A double-blind randomized placebo-controlled trial. ^[13]

placebo controlled double

METHODS N = 50 healthy participants performed antisaccade, Eriksen flanker and Simon tasks in a within-subjects, placebo-controlled, double-blind randomized design. ^[1] MATERIAL AND METHODS A short-term prospective placebo-controlled double blind randomized study of the effect of emoxypine, reamberin, mexidol on the dynamics of reduction of anxiety and depression clinical symptoms in the course of a 14-day day hospital treatment of AWS was conducted. ^[2] METHODS This multicenter placebo-controlled double-blind randomized phase III trial (ClinicalTrials. ^[3] Methods We describe a multicenter, placebo-controlled, double blind randomized clinical trial to assess the effect of calcium chloride on the need for inotropic support among adult patients during weaning from CPB. ^[4] Reference: [1] Clinical Efficacy of Leflunomide/Hydroxychloroquine Combination Therapy in Patients with Primary Sjogren’s Syndrome: Results of a Placebo-Controlled Double-Blind Randomized Clinical Trial. ^[5] We have conducted a placebo-controlled double blind randomized controlled trial [CTRI/2018/03/012897] to evaluate the effectiveness and safety of this product. ^[6]

placebo controlled study

The first stage; a double-blind randomized placebo-controlled study will focus on identifying the optimal dose to achieve meaningful change in GSH and Glu during short-term (4 weeks) NAC treatment in 36 women aged 16–24 years with NSSI. ^[1] Methods This double-blind randomized placebo-controlled study will investigate the efficacy of probiotics to prevent radiation-induced enteropathy in patients with gynecologic or urologic cancer who received pelvic radiotherapy. ^[2] The study was a double-blind randomized placebo-controlled study of five adults (3 on pitolisant and 2 on placebo), 4 men, with long-duration T1D. ^[3] Methods: This was a double-blind randomized placebo-controlled study on the efficacy and safety of intravenous TXA in reducing blood loss in women undergoing vaginal delivery in a tertiary hospital. ^[4] The pharmacological treatment of both complex interwoven mental diseases is still challenging given the inconsistent results of open and double-blind randomized placebo-controlled studies with approved and open label medications. ^[5] This single-blind randomized placebo-controlled study examined 122 young healthy women. ^[6]

clinical trial study

In the current double-blind randomized clinical trial study, we designed a new Verbal Working Memory-Balance (VWM-B) program which was carried out using a portable robotic device. ^[1] In the current double-blind randomized clinical trial study, we have designed a new Verbal Working Memory-Balance (VWM-B) program, and a portable robotic device was adopted and developed to perform the program. ^[2] Methods: A double-blind randomized clinical trial study was carried out on patients referred to emergency departments (EDs) due to isolated limb traumatic injuries. ^[3] Methods: This double-blind randomized clinical trial study was performed on 120 patients undergoing cesarean section at Hamadan Fatimah Hospital in 2019. ^[4] A double-blind randomized clinical trial study was carried out in 24 patients (i. ^[5] METHODS This double-blind randomized clinical trial study was conducted in 2017 to compare the therapeutic effects of intradermal sterile water with those of intravenous morphine on patients with renal colic presenting to the emergency departments (ED) of Imam Khomeini and Golestan Hospitals in Ahvaz, Iran. ^[6]

sham controlled trial

METHODS We performed a single-blind randomized sham-controlled trial with two parallel arms in an outpatient clinic of physical medicine and rehabilitation at a teaching hospital. ^[1] Methods We conducted a two-site pilot double-blind randomized sham-controlled trial, combining active MBSR with either active or sham tDCS. ^[2] This article presents the data of a double-blind randomized sham-controlled trial investigating the effect of prefrontal tDCS on knot-tying performance [7]. ^[3] Therefore, we performed a double-blind randomized sham-controlled trial in which rTMS was applied to the left dorsolateral prefrontal cortex of aMCI patients recruited from a community near the Third Hospital Affiliated to Sun Yat-sen University, China. ^[4] STUDY DESIGN Multicenter double-blind randomized sham-controlled trial. ^[5] Cruff J, Khandwala S, A Double-Blind Randomized Sham-Controlled Trial to Evaluate the Efficacy of Fractional Carbon Dioxide Laser Therapy on Genitourinary Syndrome of Menopause. ^[6]

controlled trial conducted

DESIGN AND PARTICIPANTS This was a double-blind randomized controlled trial conducted on 73 patients suffering from major depressive disorder in Shiraz, Iran, in 2016. ^[1] Methods: A double blind randomized controlled trial conducted among children undergoing adenotonsillectomy at a tertiary hospital in Korea from November 2018 to June 2019. ^[2] METHODS Single-blind randomized controlled trial conducted at Unidade Recomeço Helvétia (URH), a public ambulatory treatment program for persons who use crack and live in the "Crackland" region in downtown São Paulo, Brazil. ^[3] Method This is a multicenter, single-blind randomized controlled trial conducted in four Danish chiropractic clinics, 2015–2019. ^[4] METHODS This was a post hoc analysis of the ViKCoVaC (effect of Vitamin-K1 and Colchicine on Vascular Calcification activity in subjects with Diabetes Mellitus) double-blind randomized controlled trial conducted in Perth, Western Australia. ^[5] This was a double-blind randomized controlled trial conducted at a single tertiary academic center between 2019 and 2020 on adult patients undergoing elective laparoscopic TAPP inguinal hernia repair. ^[6]

single center parallel

This was a single-center, parallel group, single-blind randomized controlled trial. ^[1] A single center parallel double-blind randomized clinical trial with 6 months of follow-up was performed in patients with persistent IGT after 12 months of treatment with metformin and lifestyle; patients were randomized to continue with metformin 850 mg twice daily (M group, n = 12) or linagliptin/metformin 2. ^[2] Methods: In a single-center, parallel group, double-blind randomized controlled trial, patients >50 years of age with calcific aortic stenosis (peak aortic jet velocity >2. ^[3] METHODS A single center parallel double-blind randomized clinical trial with 24 months of follow-up in patients with impaired glucose tolerance plus two T2D risk factors which were randomized to linagliptin 5 mg + metformin 1700 mg daily + lifestyle (LM group) or metformin 1700 mg daily + lifestyle (M group). ^[4]

clinical trial conducted

METHODS Quadruble-blind randomized clinical trial conducted between November 2019 and September 2020 involving 76 patients undergoing cervical dilatation prior to surgical hysteroscopy at teaching hospitals in Pernambuco, Brazil. ^[1] This double blind randomized clinical trial conducted on 150 women undergoing cesarean section. ^[2] METHODS This is a single blind randomized clinical trial conducted at surgery main operation theatre, surgery indoor wards for a duration of 2 years. ^[3] Methods This was a double-blind randomized clinical trial conducted on 36 patients hospitalized in Ahvaz Imam Khomeini Hospital for coronary artery bypass graft. ^[4]

controlled trial comparing

Method An assessor-blind randomized controlled trial comparing the MCT-OCD (n = 39) to a care as usual control condition (n = 40) was conducted. ^[1] Patients and methods  We performed a single-blind randomized controlled trial comparing music with no music in children aged 2 to 18 years. ^[2] A fully powered single-blind randomized controlled trial comparing VRT to CBT is underway. ^[3] MethodsWe conducted a pilot double blind randomized controlled trial comparing Gelfoam with Embospheres in women undergoing UAE. ^[4]

controlled pilot trial

METHODS This single-blind randomized controlled pilot trial was conducted between 23/8/2019 and 10/1/2020. ^[1] To determine if combined therapy of bilateral tDCS and ocular occlusion improves visual function in adults with amblyopia, we conducted a double blind randomized, controlled pilot trial in volunteers with amblyopia (ClinicalTrials. ^[2] Methods In a single blind randomized controlled pilot trial (RCT), twenty participants with BMI between 20 and 40 kg/m2 were randomized to consume a 20 fluid ounce soda (SSB, 248 kcal) or the equivalent in solid form (SSS; similar to thick gelatin or gummy candy) daily. ^[3] METHODS A double blind randomized controlled pilot trial was designed. ^[4]

single center double

NAFLD patients without type 2 diabetes mellitus were enrolled in this single center double-blind randomized prospective study, and allocated to receive either dapagliflozin (SGLT2i) or teneligliptin (DPP4i) for 12 weeks. ^[1] Methods: This study will be a prospective, single-center, double-blind randomized controlled trial. ^[2] Current study is a single center double blind randomized control equivalence trial comparing efficacy of shorter duration (3 doses) of peri-operative antibiotics versus 9 doses in preventing infective complications after live liver donor hepatectomy. ^[3] HI-PRO is a single-center, double-blind randomized trial. ^[4]

patients undergoing elective

METHODS This double-blind randomized clinical trial was conducted in patients undergoing elective oesophagogastroduodenoscopy, who met the inclusion criteria. ^[1] Methods: This double-blind randomized clinical trial investigated 46 hands (23 patients) undergoing elective orthopedic surgery referring to our hospital from May to September 2017. ^[2] Material and Methods: A prospective, double-blind randomized clinical trial involving adult patients undergoing elective hip surgery, performed under subarachnoid block. ^[3]

sufficiently powered double

Conclusions: a novel 5-day-protocol to safely and effectively cure COVID-19 using repurposed immunomodulatory safe and inexpensive FDA approved drugs is illustrated and we recommend performing sufficiently powered double-blind randomized clinical trials. ^[1] Finally, we repeat our previous call to adopt our observational study that used these drugs in sufficiently powered double blind randomized clinical trials. ^[2] A novel 5-day-protocol to safely and effectively cure COVID-19 using repurposed immunomodulatory safe and inexpensive FDA approved drugs is illustrated and we recommend performing sufficiently powered double blind randomized clinical trials against any current standard protocol. ^[3]

controlled trial study

Methods: A single blind randomized controlled trial study was conducted in a stroke unit of a tertiary hospital in a Bangkok setting. ^[1] Materials and methods: Forty-five women of reproductive age with at least one endometriotic cyst were recruited into this single-blind randomized controlled trial study and randomly divided equally into three groups. ^[2] Methods In this triple-blind randomized controlled trial study, fifty 20–45-year-old infertile men with idiopathic abnormal sperm parameters were selected among men referring to the infertility clinic of Al Zahra-Iran Hospital, and randomly allocated into two groups. ^[3]

single center single

Methods For this single-center, single-blind randomized controlled clinical trial, 10 male and 87 female participants with RA, aged 50–75 years, who underwent unilateral primary TKA were recruited. ^[1] Methods/design This is a prospective single-center single-blind randomized controlled trial. ^[2] Study design The LImited access Aortic valve Replacement (LIAR) trial is a single-center, single blind randomized controlled clinical trial comparing 2 arms of 80 patients undergoing limited access SAVR via J-shaped upper hemi-sternotomy (UHS) or conventional SAVR through FMS. ^[3]

left dorsolateral prefrontal

Methods: In this double-blind randomized sham-controlled study, 30 subjects received either active iTBS treatment (10 sessions, two sessions a day) or sham treatment over the left dorsolateral prefrontal cortex. ^[1] METHODS Forty-four CUD patients were randomly assigned to complete the 2-week double-blind randomized controlled trial (acute phase) [Sham (n=20, 2 female) and Active (n=24, 4 female)], in which they received 2 daily sessions of rTMS on the left dorsolateral prefrontal cortex. ^[2]

clinical trial aimed

OBJECTIVE The present double-blind randomized clinical trial aimed to compare the efficacy of conservative treatment and articular lavage, either alone or combined, to reduce joint pain and improve mandibular opening. ^[1] This double‐blind randomized clinical trial aimed to investigate impact of Cornus mas L. ^[2]

controlled trial evaluating

METHODS A single blind randomized controlled trial evaluating sixty-six healthy participants including 58 females and 8 males aged between 40 and 65 years. ^[1] Objective This is the first double-blind randomized controlled trial evaluating the efficacy and safety of IV immunoglobulin (IVIG) vs placebo in patients with idiopathic small fiber neuropathy (I-SFN). ^[2]

Double Blind Randomized

METHODS A double blind randomized controlled trial was conducted at the oral and maxillofacial surgery OPD at DUHS, Karachi. ^[1] Methods This is a double blind randomized controlled trial on 105 HD patients was conducted at a large educational hospital in Iran, Hamadan province between January and September 2017. ^[2] Subjek dan Metode: Penelitian double blind randomized control trial pada 36 pasien yang memenuhi kriteria. ^[3] Methods A double blind randomized trial. ^[4] 6 years) were studied in a double blind randomized-sequence cross-over study, in which they underwent tests for cognitive function (digit span, verbal/word fluency, and Stroop), neuromuscular performance (sharpened Romberg and dart throwing), and exercise performance (estimated aerobic capacity, hand-grip strength, vertical jump, and push-up) after acute ingestion of huperzine A (200 mcg) or placebo. ^[5] Finally, we repeat our previous call to adopt our observational study that used these drugs in sufficiently powered double blind randomized clinical trials. ^[6] We carry out a double blind randomized online experiment with a sample of N=4000 Americans to study (i) whether two nudges can increase the level of support for a COVID pass for international traveling, (ii) the relationship between the effects of the nudges, and (iii) if these nudges have a negative spillover on the intention to get vaccinated. ^[7] This double blind randomized clinical trial conducted on 150 women undergoing cesarean section. ^[8] METHODS In this prospective, noninferiority, double blind randomized controlled efficacy trial, patients received either OO-based or SO-based IVLE after providing consent. ^[9] The purpose of this prospective double blind randomized clinical trial was to evaluate the combined effect of oral premedication with ibuprofen and dexamethasone on the success rate of inferior alveolar nerve block in