Introduction to Barrier Response

Data from RNA-sequencing combined with reporter line and mutant studies identified essential roles for reactive oxygen species, ethylene and auxin signalling during the barrier response.

Genetic disruption of ACh synthesis by murine ILC2s resulted in increased parasite burdens, lower numbers of ILC2s, and reduced lung and gut barrier responses to Nippostrongylus brasiliensis infection.

The in-depth research on SC barrier, its disruption in the pathogenesis of diseases, as well as on barrier responses to environmental insults, has enabled the development of modern therapeutics and topical care routines.

Bi-directional crosstalk between IAV-exposed epithelial cells and eosinophils occurred after IAV infection and cross-regulation promoted barrier responses to improve antiviral defenses in airway epithelial cells.

Utilizing changes in transendothelial electricial resistance (TEER) to measure endothelial cell barrier responses, we demonstrate that EVL expression regulates endothelial cell responses to both sphingosine-1-phospate (S1P), a vascular barrier-enhancing agonist, and to thrombin, a barrier-disrupting stimulus.

Mechanistic evidence linking gut microbial changes and host mucosal barrier responses in patients with Crohn’s disease (CD) is lacking.

were mainly determined by barrier response to the Holocene transgression and changes in storminess.

The signatures of runup and pile-up mechanisms are thoroughly analyzed, in terms of flow features and barrier responses.

Numerical simulations of barrier response to bimodal storm conditions, which are a common occurrence in many parts of the UK were also investigated.

Correctly and carefully developed numerical simulations give unique insight into the impact mechanism and allows for comprehensive understanding of barrier responses.

The dynamic impact and the corresponding non-linear barrier response require numerical models.

Polyolefins are considered among the most difficult polymeric materials to treat because they have poor adhesive properties and high chemical barrier responses.

The mechanosensor Piezo1, a plasma membrane cation channel, was inducibly deleted in endothelial cells of mice (Piezo1iEC-/-), which allowed us to study its role in regulating the endothelial barrier response to alveolar stretch.

In addition, the effects of boulder size, impact position, barrier inclination, and barrier initial slack on barrier response in a parametric study are investigated.

The proposed scheme and dimensions are tested using geomorphological data from barrier response to distinct disturbances, over different temporal scales that range from event to multi-decadal ones.

Barrier responses to interferon-γ of intestinal organoids with and without epithelial cell-specific deletion of the interferon-γ-receptor 2 gene were used as a model system.

Developing innovative products that preserve and improve skin barrier function requires a thorough understanding of the mechanisms underlying barrier response to topical applications.

T cells expressing invariant γδ antigen receptors (γδ T cells) bridge innate and adaptive immunity and facilitate barrier responses to pathogens.

The impact kinematics and barrier responses, such as mobilized structural forces and elongation of cables, were recorded synchronously.