Introduction to Antibiotic Allergy

What is/are Antibiotic Allergy?

Antibiotic Allergy - BACKGROUND Antibiotic allergy labels (AALs), reported by up to 25% of hospitalized patients, are a significant barrier to appropriate prescribing and a focus of antimicrobial stewardship (AMS) programmes. ^[1] We evaluated the feasibility and outcomes of an antibiotic allergy evaluation program prior to allogeneic HCT. ^[2] Results Among 2153 SOT (65%) and HCT (35%) recipients, 634 (29%) reported any antibiotic allergy and 347 (16%) reported BLAs (Figure 1). ^[3] Nowadays, it is mandatory to rigorously confirm or exclude a diagnosis of antibiotic allergy to improve patient safety by using the most appropriate antibiotic depending on the infection to be treated and avoid alternative often more expensive, favoring antibiotic resistance. ^[4] The relationship between hematological malignancy and chemotherapy on the prevalence of antibiotic allergy label (AAL) is ill-defined. ^[5] BACKGROUND Antibiotic allergy labels have a direct impact on individual patient care and on the consumption of broad-spectrum antibiotics. ^[6] Purpose To assess the prevalance and characteristics of antibiotic allergy and to differentiate cases where the allergic nature of drug raction can be excluded/or has weak grounding. ^[7] 2019;7(3):975–982 To examine whether antibiotic allergy labeling has a significant impact on clinical outcomes in children. ^[8] Antibiotic allergy labels result in displacement of first-line therapies for antibiotic prophylaxis and treatment. ^[9] We sought to evaluate if there is a relationship between patients with an antibiotic allergy label and prevalence of MRSA or VRE colonization. ^[10] Antibiotic allergy labels (AALs) are reported by approximately 20% of hospitalized patients, yet over 85% will be negative on formal allergy testing. ^[11] The general search terms used were oncology, cancer, hematologic malignancy, antimicrobial stewardship, antibiotic stewardship, febrile neutropenia, neutropenic fever, de-escalation, discontinuation, prophylaxis, practice guidelines, clinical pathway, rapid diagnostics, Filmarray, Verigene, MALDI-TOF, antibiotic allergy, and antimicrobial resistance. ^[12] Background Limited data are available on non-β-lactam (NBL) antibiotic allergy labeling in children. ^[13] However, there is a paucity of studies investigating the impact of an antibiotic allergy label in childhood. ^[14] AIM A comparative evaluation of the efficacy and safety of Canephron N and Cystone as monotherapy in women with acute uncomplicated cystitis and antibiotic allergy or intolerance was performed. ^[15] Busy clinicians seldom have time to explore the history of suspected antibiotic allergies in detail; an important role of the antibiotic allergy service is to do just this, including gathering contemporaneous notes, charts, and correspondence where necessary. ^[16] Antibiotic allergy de‐labeling using penicillin allergy skin testing (PAST) can reduce the use and cost of alternative, non‐β‐lactam antibiotics in general inpatient populations. ^[17] We designed an accessible app to bring antibiotic prescribing and antibiotic allergy decision-making to prescribers at point of care. ^[18] Conclusion We identified an antibiotic allergy point prevalence rate of 49. ^[19] Recent attention has focused on antibiotic allergy labels and the benefits of delabelling. ^[20] RESULTS Among 2153 SOT (65%) and HCT (35%) recipients, 634 (29%) reported any antibiotic allergy and 347 (16%) reported BLA. ^[21] Within the broad category of adverse drug reactions in children, there has been a recent focus specifically on the evaluation of children with antibiotic allergy, in particular, beta-lactam allergy. ^[22]

assess oral cephalosporin

We aimed to assess oral cephalosporin antibiotic allergy in children through the use of a graded oral challenge (GOC). ^[1] We aimed to assess oral cephalosporin antibiotic allergy in children through the use of a graded oral challenge (GOC). ^[2] We aimed to assess oral cephalosporin antibiotic allergy in children through the use of a graded oral challenge (GOC). ^[3]

Lactam Antibiotic Allergy

The girl was admitted to a paediatric allergy clinic due to a suspicion of β-lactam antibiotic allergy (current presentation). ^[1] This study aimed to evaluate the impact of common β-lactam antibiotic allergy labels (AALs) on hospital treatment, focussing on length of stay and appropriateness of antibiotic prescribing. ^[2] BACKGROUND Clarithromycin hypersensitivity is reported as the most common cause of non-β-lactam antibiotic allergy in children. ^[3] The validation of a beta-lactam antibiotic allergy assessment allows non-allergists to effectively phenotype patient-reported antibiotic allergies and direct them to appropriate 'de-labeling' stratergies. ^[4]

Cephalosporin Antibiotic Allergy

We aimed to assess oral cephalosporin antibiotic allergy in children through the use of a graded oral challenge (GOC). ^[1] We aimed to assess oral cephalosporin antibiotic allergy in children through the use of a graded oral challenge (GOC). ^[2] We aimed to assess oral cephalosporin antibiotic allergy in children through the use of a graded oral challenge (GOC). ^[3]

Reported Antibiotic Allergy

Few studies have examined the relationship between a reported antibiotic allergy and risk of SSI and to what extent this relationship is modified by the antibiotic class given for prophylaxis. ^[1] BACKGROUND Reported antibiotic allergy in hospitalized patients seems to be related to more adverse events, the use of reserve antibiotics and longer hospitalizations. ^[2]

antibiotic allergy label

This study aimed to evaluate the impact of common β-lactam antibiotic allergy labels (AALs) on hospital treatment, focussing on length of stay and appropriateness of antibiotic prescribing. ^[1] Background Suboptimal antibiotic prescriptions in patients with an antibiotic allergy label lead to increased incidence of adverse events and antimicrobial resistance (AMR). ^[2] Up to 10% of hospitalized patients have an antibiotic allergy label in their medical file, most frequently concerning penicillins. ^[3] BACKGROUND Antibiotic allergy labels (AALs), reported by up to 25% of hospitalized patients, are a significant barrier to appropriate prescribing and a focus of antimicrobial stewardship (AMS) programmes. ^[4] The relationship between hematological malignancy and chemotherapy on the prevalence of antibiotic allergy label (AAL) is ill-defined. ^[5] BACKGROUND Antibiotic allergy labels have a direct impact on individual patient care and on the consumption of broad-spectrum antibiotics. ^[6] Antibiotic allergy labels result in displacement of first-line therapies for antibiotic prophylaxis and treatment. ^[7] We sought to evaluate if there is a relationship between patients with an antibiotic allergy label and prevalence of MRSA or VRE colonization. ^[8] Antibiotic allergy labels (AALs) are reported by approximately 20% of hospitalized patients, yet over 85% will be negative on formal allergy testing. ^[9] However, there is a paucity of studies investigating the impact of an antibiotic allergy label in childhood. ^[10] Results The prevalence of BL allergy labels in hospitalized HK Chinese was 5%, which was associated with female gender and concomitant non-BL antibiotic allergy labels. ^[11] Background Antibiotic allergy labels lead to excess exposure to broad-spectrum antibiotics and can result in patient harm. ^[12] Recent attention has focused on antibiotic allergy labels and the benefits of delabelling. ^[13]

antibiotic allergy evaluation

Targeted antibiotic allergy evaluations are increasingly recognized as an important strategy for optimization of antimicrobial stewardship. ^[1] We evaluated the feasibility and outcomes of an antibiotic allergy evaluation program prior to allogeneic HCT. ^[2]

antibiotic allergy labeling

2019;7(3):975–982 To examine whether antibiotic allergy labeling has a significant impact on clinical outcomes in children. ^[1] Background Limited data are available on non-β-lactam (NBL) antibiotic allergy labeling in children. ^[2]

antibiotic allergy testing

Part-1: Determine the cost per effectively delabeled patient for Penicillin Allergy Delabeling Program inpatients (PADP cohort) compared to Outpatient Antibiotic Allergy Testing Service outpatients (OAATS cohort). ^[1] AIMS The aims of this study were to characterize antibiotic choices for perioperative total knee arthroplasty (TKA) and total hip arthroplasty (THA) prophylaxis, assess antibiotic allergy testing efficacy, and determine rates of prosthetic joint infection (PJI) based on perioperative antibiotic regimen. ^[2]

antibiotic allergy assessment

Aims To determine whether non-allergy specialist health-care workers can use an antibiotic allergy assessment tool (AAAT) to correctly phenotype and manage reported penicillin allergy. ^[1] The validation of a beta-lactam antibiotic allergy assessment allows non-allergists to effectively phenotype patient-reported antibiotic allergies and direct them to appropriate 'de-labeling' stratergies. ^[2]